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ARVO Annual Meeting Abstract June 2022

Cell Autonomous Lipid Handling Defects in Stargardt iPS Cell-Derived Retinal Pigment Epithelium Cells

Mitra Farnoodian-Tedrick; Devika Bose; Indumathi Mariappan; Maria M Campos; Rafael Villasmil; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):462. doi:

ARVO Annual Meeting Abstract June 2022

Senescent Macrophage Lead to Age Related Macular Degeneration-Like Phenotype in an in vitro 3D RPE/Choroid Model

Russell Quinn; Eric Nguyen; Tea Soon Park; Congxiao Zhang; Amir Ali; Rishabh Hirday; Devika Bose; Robert N Fariss; Marc Ferrer; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):24. doi:

ARVO Annual Meeting Abstract June 2022

Generation of choroid and RPE cells from iPSC with CFH knockout for modeling of AMD

Tea Soon Park; Russell Quinn; Rishabh Hirday; Amir Ali; Eric Nguyen; Devika Bose; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1474. doi:

ARVO Annual Meeting Abstract June 2022

CRISPR -Cas9-mediated gene correction in Induced Pluripotent Stem Cells derived from Oculocutaneous Albinism Type 2 patients rescues pigmentation defect in Retinal Pigment Epithelium

Arnold Leigh; Tyler Pfister; Aman George; Ruchi Sharma; Mones Abu-Asab; Kapil Bharti; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1472. doi:

ARVO Annual Meeting Abstract June 2022

DEVELOPMENT OF AN RPE-SPECIFIC IN VITRO STARGARDT DISEASE MODEL

Devika Bose; Mitra Farnoodian; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2435 – F0379. doi:

ARVO Annual Meeting Abstract June 2022

Derivation of iPSC monocyte to study immune reaction of early AMD using isogenic 3D choroid/RPE model

Rishabh Hirday; Tea Soon Park; Russell Quinn; Amir Ali; Eric Nguyen; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2434 – F0378. doi:

ARVO Annual Meeting Abstract June 2022

iPSC-RPE with CFH Y402H risk variant show higher disease propensity compared to the non-risk CFH variant

Ruchi Sharma; Malika Nimmagadda; Davide Ortolan; Kelcy Klein; Jair Montford; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2431 – F0375. doi:

ARVO Annual Meeting Abstract June 2022

Automatic retinal layer segmentation in OCT images of a laser induced porcine model for retinal injury

Rohan Gupta; Samuel Heaps; Bruno Alvisio; Francesca BARONE; Arvydas Maminishkis; Juan Amaral; Irina Bunea; Kristi Creel; Mitra Farnoodian; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2081 – F0070. doi:

ARVO Annual Meeting Abstract June 2022

Targeted deletion of interferon regulatory factor 5 gene in mice triggers choroidal neovascularization

Congxiao Zhang; Russell Quinn; Eric Nguyen; Nilisha Fernando; Joys Annika G David; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3477. doi:

ARVO Annual Meeting Abstract June 2022

3D-Bioprinted Outer Blood Retinal Barrier Model to Characterize the Role of Senescent Fibroblasts in Driving RPE Dysfunction

Amir Ali; Eric Nguyen; Rishabh Hirday; Russell Quinn; Devika Bose; Minhye Kwak; Jair Montford; Tea Soon Park; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3154 – F0428. doi:

ARVO Annual Meeting Abstract June 2022

Retinal Pigment Epithelium Modulates Endothelial Cell, Fibroblast, and Pericyte Gene Expression Patterns in 3D Bioprinted Tissues

Eric Nguyen; Min Jae Song; Russell Quinn; Tea Soon Park; Yu-Chi Chen; Claire Malley; Carlos Tristan; Devika Bose; Ruchi Sharma; Roba Dejene; Amir Ali; Rishabh Hirday; Arvydas Maminishkis; Ilyas Singec; Marc Ferrer; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3027 – F0398. doi:

ARVO Annual Meeting Abstract June 2022

Cellular transformation and polarization in differentiating iPSC-derived retinal pigment epithelium

Zander Esh; Davide Ortolan; Jair Montford; Malika Nimmagadda; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3741 – F0347. doi:

ARVO Annual Meeting Abstract June 2022

Morphometric analysis of the human retinal pigment epithelium indicates regional susceptibilities to disease

Sharanya Suresh; Davide Ortolan; Ruchi Sharma; Andrei Volkov; Arvydas Maminishkis; Nathan Hotaling; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4623 – F0415. doi:

ARVO Annual Meeting Abstract June 2022

Single cell resolution map of retinal pigment epithelium helps discover subpopulations with differential disease sensitivity

Davide Ortolan; Ruchi Sharma; Andrei Volkov; Arvydas Maminishkis; Nathan Hotaling; Laryssa Huryn; Stefano Di Marco; Silvia Bisti; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4616 – F0408. doi:

ARVO Annual Meeting Abstract June 2022

TLR3 and TLR4 regulate complement-induced AMD cellular phenotype in iPSC-derived retinal pigment epithelium

Joys Annika G David; Congxiao Zhang; Andrew Fausey; Ruchi Sharma; Mitra Farnoodian; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4614 – F0406. doi:

ARVO Annual Meeting Abstract June 2021

Using Adaptive Optics to Evaluate Photoreceptor Regularity in a Porcine Laser Model Mimicking Age-Related Macular Degeneration

Rishabh Gupta; Francesca BARONE; Dara Baker; Devika Bose; Haig Pakhchanian; Irina Bunea; Arvydas Maminishkis; Davide Ortolan; Joe Phillips; Ruchi Sharma; Juan Amaral; David Gamm; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):11. doi:

ARVO Annual Meeting Abstract June 2021

Modeling the outer blood-retina barrier using microfluidic chips and iPSC-derived RPE and endothelial cells

Tea Soon Park; Eric Nguyen; Haig Pakhchanian; Davide Ortolan; Nikhil Vettikatu; Roba Dejene; Devika Bose; Genqing Liang; Ruchi Sharma; Arvydas Maminishkis; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2192. doi:

ARVO Annual Meeting Abstract June 2021

Human retinal pigment epithelium secretes insulin-like growth factor 2 in vitro

Charles DeYoung; Tyler Pfister; Congxiao Zhang; Aman George; Kapil Bharti; Tiziana Cogliati; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2991. doi:

ARVO Annual Meeting Abstract June 2021

The human retinal pigment epithelium has five morphometrically distinct subpopulations which present differential disease vulnerability

Davide Ortolan; Ruchi Sharma; Andrei Volkov; Arvydas Maminishkis; Jorge Ferrari Escoto; Nathan Hotaling; Stefano Di Marco; Silvia Bisti; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2717. doi:

ARVO Annual Meeting Abstract June 2021

Interaction between CTRP5 & AdipoR1 and its implication to Late-onset retinal degeneration (L-ORD)

Andrew Fausey; Congxiao Zhang; Malika Nimmagadda; Kiyoharu Joshua Miyagishima; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3062. doi:

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Cell Autonomous Lipid Handling Defects in Stargardt iPS Cell-Derived Retinal Pigment Epithelium Cells

Senescent Macrophage Lead to Age Related Macular Degeneration-Like Phenotype in an in vitro 3D RPE/Choroid Model

Generation of choroid and RPE cells from iPSC with CFH knockout for modeling of AMD

CRISPR -Cas9-mediated gene correction in Induced Pluripotent Stem Cells derived from Oculocutaneous Albinism Type 2 patients rescues pigmentation defect in Retinal Pigment Epithelium

DEVELOPMENT OF AN RPE-SPECIFIC IN VITRO STARGARDT DISEASE MODEL

Derivation of iPSC monocyte to study immune reaction of early AMD using isogenic 3D choroid/RPE model

iPSC-RPE with CFH Y402H risk variant show higher disease propensity compared to the non-risk CFH variant

Automatic retinal layer segmentation in OCT images of a laser induced porcine model for retinal injury

Targeted deletion of interferon regulatory factor 5 gene in mice triggers choroidal neovascularization

3D-Bioprinted Outer Blood Retinal Barrier Model to Characterize the Role of Senescent Fibroblasts in Driving RPE Dysfunction

Retinal Pigment Epithelium Modulates Endothelial Cell, Fibroblast, and Pericyte Gene Expression Patterns in 3D Bioprinted Tissues

Cellular transformation and polarization in differentiating iPSC-derived retinal pigment epithelium

Morphometric analysis of the human retinal pigment epithelium indicates regional susceptibilities to disease

Single cell resolution map of retinal pigment epithelium helps discover subpopulations with differential disease sensitivity

TLR3 and TLR4 regulate complement-induced AMD cellular phenotype in iPSC-derived retinal pigment epithelium

Using Adaptive Optics to Evaluate Photoreceptor Regularity in a Porcine Laser Model Mimicking Age-Related Macular Degeneration

Modeling the outer blood-retina barrier using microfluidic chips and iPSC-derived RPE and endothelial cells

Human retinal pigment epithelium secretes insulin-like growth factor 2 in vitro

The human retinal pigment epithelium has five morphometrically distinct subpopulations which present differential disease vulnerability

Interaction between CTRP5 & AdipoR1 and its implication to Late-onset retinal degeneration (L-ORD)

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