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ARVO Annual Meeting Abstract July 2019

Change of baseline visual acuity in eyes with age-related macular degeneration from 2006-201 5

Tomoko Sawada; Tsutomu Yasukawa; Hiroko Imaizumi; Hisashi Mastubara; Kazuhiro Kimura; Hiroto Terasaki; Hiroto Ishikawa; Tomoya Murakami; Masaru Takeuchi; Yoshinori Mitamura; Mariko Yamashita; Yoshihiro Takamura; Toshinori Murata; Jiro Kogo; Taiji Sakamoto; Masahito Ohji

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1160. doi:

ARVO Annual Meeting Abstract July 2019

Vascular endothelial growth factor secretion induced by endogenous danger signals in retinal pigment epithelial cells

Makoto Hatano; Masaaki Kobayashi; Sho-Hei Uchi; Yuka Kobayashi; Chiemi Yamashiro; Kazuhiro Tokuda; Ryoji Yanai; Kazuhiro Kimura

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1933. doi:

ARVO Annual Meeting Abstract July 2019

Suppression of TGF-β2-induced RPE cells contraction by RAR-α agonist

Yuka Kobayashi; Chiemi Yamashiro; Makoto Hatano; Masaaki Kobayashi; Sho-Hei Uchi; Kazuhiro Tokuda; Ryoji Yanai; Kazuhiro Kimura

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2375. doi:

ARVO Annual Meeting Abstract July 2019

Co-culture with corneal epithelial cells decreases transformation of tenon`s capsule fibroblasts into myofibroblasts by benzalkonium chloride.

Chiemi Yamashiro; Kazuhiro Tokuda; Yuka Kobayashi; Makoto Hatano; Masaaki Kobayashi; Sho-Hei Uchi; Shinichiro Teranishi; Kazuhiro Kimura

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):255. doi:

ARVO Annual Meeting Abstract July 2019

Change in 1-year visual acuity gain with age-related macular degeneration from 2006 and 2015

Sachi Nishino; Tsutomu Yasukawa; Hiroko Imaizumi; Hisashi Mastubara; Hiroto Ishikawa; Kazuhiro Kimura; Hiroto Terasaki; Yoshinori Mitamura; Toshinori Murata; Mariko Yamashita; Jiro Kogo; Masaru Takeuchi; Yoshihiro Takamura; Tomoya Murakami; Taiji Sakamoto; Masahito Ohji

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):92. doi:

Retina February 2019

Suppression of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells by an MRTF-A Inhibitor

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Masaaki Kobayashi; Kazuhiro Tokuda; Yuka Kobayashi; Chiemi Yamashiro; Sho-Hei Uchi; Makoto Hatano; Kazuhiro Kimura
TAGS: fibrosis, cell motility, choroidal neovascularization, gelatin, gelatinase a, immunoblotting, mice, proteins, epithelial to mesenchymal transition, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):528-537. doi: 10.1167/iovs.18-25678

ARVO Annual Meeting Abstract July 2018

Quantification of Vitreous Opacity by a Newly Developed Method Based on Analysis of Interframe Differences in Slitlamp Movies

Chiemi Yamashiro; Ayana Nishimoto; Yuka Kobayashi; Syohei Uchi; Makoto Hatano; Masaaki Kobayashi; Tomoko Orita; Kazuhiro Tokuda; Ryu Takabatake; Makiko Takahashi; Kazuhiko Yamauchi; Eiji Uchino; Kazuhiro Kimura

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1686. doi:

ARVO Annual Meeting Abstract July 2018

Inhibitional effect of TGF-β2-induced EMT in RPE cells by an RAR-γ agonist

Yuka Kobayashi; Tomoko Orita; Chiemi Yamashiro; Syohei Uchi; Makoto Hatano; Masaaki Kobayashi; Kazuhiro Tokuda; Ryoji Yanai; Atsunobu Takeda; Tatsuro Ishibashi; Koh-hei Sonoda; Kazuhiro Kimura

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4003. doi:

ARVO Annual Meeting Abstract June 2017

Synergistic attenuation of choroidal neovascularization by dietary intake of ω-3 long-chain polyunsaturated fatty acids and lutein in mice

Ryoji Yanai; Shang Chen; Sho-hei Uchi; Tomoaki Nanri; Kazuhiro Kimura

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2304. doi:

Cornea April 2017

Suppression by an RAR-γ Agonist of Collagen Degradation Mediated by Corneal Fibroblasts

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Kazuhiro Kimura; Hongyan Zhou; Tomoko Orita; Masaaki Kobayashi; Teruo Nishida; Koh-Hei Sonoda
TAGS: fibroblast, collagen, oryctolagus cuniculus, cornea, agonists, catabolism
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):2250-2257. doi: 10.1167/iovs.15-18701

Retina April 2016

Vascular Normalization by ROCK Inhibitor: Therapeutic Potential of Ripasudil (K-115) Eye Drop in Retinal Angiogenesis and Hypoxia

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Muneo Yamaguchi; Shintaro Nakao; Ryoichi Arita; Yoshihiro Kaizu; Mitsuru Arima; Yedi Zhou; Takeshi Kita; Shigeo Yoshida; Kazuhiro Kimura; Tomoyuki Isobe; Yoshio Kaneko; Koh-hei Sonoda; Tatsuro Ishibashi
TAGS: angiogenesis, vascular endothelial growth factor a, hypoxia, mice, retina, eyedrops
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):2264-2276. doi: 10.1167/iovs.15-17411

Includes: Supplemental Content

Immunology and Microbiology November 2015

Distinct Profiles of Soluble Cytokine Receptors Between B-Cell Vitreoretinal Lymphoma and Uveitis

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Atsunobu Takeda; Hiroshi Yoshikawa; Takako Fukuhara; Shin-Ichi Hikita; Kuniaki Hijioka; Takaaki Otomo; Ryoichi Arita; Toshio Hisatomi; Kazuhiro Kimura; Shigeo Yoshida; Yo-Ichi Kawano; Koh-Hei Sonoda; Tatsuro Ishibashi
TAGS: cytokine, b-lymphocytes, lymphoma, receptors, cytokine, uveitis, vitreous body, squamous intraepithelial lesion, pmel17
Invest. Ophthalmol. Vis. Sci.. 2015; 56(12):7516-7523. doi: 10.1167/iovs.15-17465

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Relation between acute intraocular pressure elevation after intravitreal injection of an anti-VEGF drug and optic nerve head circulation

Makiko Wakuta; Miho Fukumura; Tomoko Orita; Ryoji Yanai; Kazuhiro Kimura; Koh-hei Sonoda

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3711. doi:

ARVO Annual Meeting Abstract June 2015

Coordinated Regulation of Palladin and α-Smooth Muscle Actin by Transforming Growth Factor-β in Human Corneal Fibroblast

Naoyuki Morishige; Shizuka Murata; Haruya Azumi; Ryutaro Shin-gyou-uchi; Yukiko Morita; Kazuhiro Kimura; Koh-hei Sonoda

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1937. doi:

Cornea December 2014

Quantitative Analysis of Collagen Lamellae in the Normal and Keratoconic Human Cornea by Second Harmonic Generation Imaging Microscopy

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Naoyuki Morishige; Ryutaro Shin-gyou-uchi; Haruya Azumi; Hiroaki Ohta; Yukiko Morita; Naoyuki Yamada; Kazuhiro Kimura; Atsushi Takahara; Koh-Hei Sonoda
TAGS: collagen, cornea, diagnostic imaging, harmonics
Invest. Ophthalmol. Vis. Sci.. 2014; 55(12):8377-8385. doi: 10.1167/iovs.14-15348

Glaucoma July 2014

Inhibition by All- Trans -Retinoic Acid of Transforming Growth Factor-β–Induced Collagen Gel Contraction Mediated by Human Tenon Fibroblasts

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Yang Liu; Kazuhiro Kimura; Tomoko Orita; Shinichiro Teranishi; Katsuyoshi Suzuki; Koh-Hei Sonoda
TAGS: fibroblasts, collagen, gel, tretinoin
Invest. Ophthalmol. Vis. Sci.. 2014; 55(7):4199-4205. doi: 10.1167/iovs.13-13572

ARVO Annual Meeting Abstract April 2014

Role of female sex hormones in collagen gel contraction mediated by retinal pigment epithelial cells

Tomoko Orita; Kazuhiro Kimura; Koh-hei Sonoda

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):380. doi:

Retinal Cell Biology April 2014

Inhibition by Female Sex Hormones of Collagen Gel Contraction Mediated by Retinal Pigment Epithelial Cells

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Kazuhiro Kimura; Tomoko Orita; Youichiro Fujitsu; Yang Liu; Makiko Wakuta; Naoyuki Morishige; Katsuyoshi Suzuki; Koh-Hei Sonoda
TAGS: fibronectins, estradiol, collagen, gel, gonadal steroid hormones, progesterone, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2014; 55(4):2621-2630. doi: 10.1167/iovs.13-13501

ARVO Annual Meeting Abstract June 2013

Effect of prostaglandin E2 on collagen gel contraction in mouse retinal pigment epithelium cells

Tomoko Orita; Kazuhiro Kimura; Koh-hei Sonoda

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2008. doi:

Cornea April 2013

Protection of Human Corneal Epithelial Cells From TNF-α–Induced Disruption of Barrier Function by Rebamipide

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Kazuhiro Kimura; Yukiko Morita; Tomoko Orita; Junpei Haruta; Yasuhiro Takeji; Koh-Hei Sonoda
TAGS: tumor necrosis factors, dry eye syndromes, cornea, rebamipide, corneal epithelial cells
Invest. Ophthalmol. Vis. Sci.. 2013; 54(4):2752-2760. doi: 10.1167/iovs.12-11294

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Change of baseline visual acuity in eyes with age-related macular degeneration from 2006-201 5

Vascular endothelial growth factor secretion induced by endogenous danger signals in retinal pigment epithelial cells

Suppression of TGF-β2-induced RPE cells contraction by RAR-α agonist

Co-culture with corneal epithelial cells decreases transformation of tenon`s capsule fibroblasts into myofibroblasts by benzalkonium chloride.

Change in 1-year visual acuity gain with age-related macular degeneration from 2006 and 2015

Suppression of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells by an MRTF-A Inhibitor

Quantification of Vitreous Opacity by a Newly Developed Method Based on Analysis of Interframe Differences in Slitlamp Movies

Inhibitional effect of TGF-β2-induced EMT in RPE cells by an RAR-γ agonist

Synergistic attenuation of choroidal neovascularization by dietary intake of ω-3 long-chain polyunsaturated fatty acids and lutein in mice

Suppression by an RAR-γ Agonist of Collagen Degradation Mediated by Corneal Fibroblasts

Vascular Normalization by ROCK Inhibitor: Therapeutic Potential of Ripasudil (K-115) Eye Drop in Retinal Angiogenesis and Hypoxia

Distinct Profiles of Soluble Cytokine Receptors Between B-Cell Vitreoretinal Lymphoma and Uveitis

Relation between acute intraocular pressure elevation after intravitreal injection of an anti-VEGF drug and optic nerve head circulation

Coordinated Regulation of Palladin and α-Smooth Muscle Actin by Transforming Growth Factor-β in Human Corneal Fibroblast

Quantitative Analysis of Collagen Lamellae in the Normal and Keratoconic Human Cornea by Second Harmonic Generation Imaging Microscopy

Inhibition by All- Trans -Retinoic Acid of Transforming Growth Factor-β–Induced Collagen Gel Contraction Mediated by Human Tenon Fibroblasts

Role of female sex hormones in collagen gel contraction mediated by retinal pigment epithelial cells

Inhibition by Female Sex Hormones of Collagen Gel Contraction Mediated by Retinal Pigment Epithelial Cells

Effect of prostaglandin E2 on collagen gel contraction in mouse retinal pigment epithelium cells

Protection of Human Corneal Epithelial Cells From TNF-α–Induced Disruption of Barrier Function by Rebamipide

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