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Cornea April 2022

Repressed miR-34a Expression Dictates the Cell Fate to Corneal Endothelium Failure

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Junji Hamuro; Kazuko Asada; Morio Ueno; Tomoko Yamashita; Atsushi Mukai; Tomoko Fujita; Eiko Ito; Nao Hiramoto; Munetoyo Toda; Chie Sotozono; Shigeru Kinoshita
TAGS: cd44 antigens, cells, corneal endothelium, gelatinase a, homing-associated cell adhesion molecule, micrornas, mitochondria, patient simulation, prostate health index, protected health information
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):22. doi: https://doi.org/10.1167/iovs.63.4.22

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Mitochondria as platforms for dictating differentiation/maturation of human corneal endothelial cells with distinct energy metabolism and metabolomic signatures

Kohsaku Numa; Morio Ueno; Munetoyo Toda; Atsushi Mukai; Kazuko Asada; Asako Uehara; Chie Sotozono; Shigeru Kinoshita; Jyunji Hamuro

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3450. doi:

Cornea April 2017

Production of Homogeneous Cultured Human Corneal Endothelial Cells Indispensable for Innovative Cell Therapy

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Munetoyo Toda; Morio Ueno; Asako Hiraga; Kazuko Asada; Monty Montoya; Chie Sotozono; Shigeru Kinoshita; Junji Hamuro
TAGS: cd44 antigens, cell therapy, cornea, endothelial cells, homing-associated cell adhesion molecule, homogeneity, donors, small patella syndrome, sodium polystyrene sulfonate, stiff-person syndrome
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):2011-2020. doi: https://doi.org/10.1167/iovs.16-20703

Cornea October 2016

MicroRNA Profiles Qualify Phenotypic Features of Cultured Human Corneal Endothelial Cells

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Morio Ueno; Kazuko Asada; Munetoyo Toda; Asako Hiraga; Monty Montoya; Chie Sotozono; Shigeru Kinoshita; Junji Hamuro
TAGS: cornea, endothelial cells, micrornas, phenotype, small patella syndrome, sodium polystyrene sulfonate, stiff-person syndrome, cd44 antigens, homing-associated cell adhesion molecule, patient simulation
Invest. Ophthalmol. Vis. Sci.. 2016; 57(13):5509-5517. doi: https://doi.org/10.1167/iovs.16-19804

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Profiles of cytokines in the aqueous humor and serum of bullous keratopathy patients

Morio Ueno; Munetoyo Toda; Asako Hiraga; Koichi Wakimasu; Noriko Koizumi; Naoki Okumura; Kazuko Asada; Chie Sotozono; Junji Hamuro; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):898. doi:

ARVO Annual Meeting Abstract September 2016

Regulation of mitochondrial respiration under cell culture stress in human corneal endothelial cells

Shigeru Kinoshita; Morio Ueno; Kazuko Asada; Munetoyo Toda; Kazue Nagata; Chie Sotozono; Nobuyoshi Kosaka; Takahiro Ochiya; Junji Hamuro

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

The role of dysregulated expression of miRs in the pathogenesis of bullous keratopathy and Fuchs’ endothelial corneal dystrophy

Kazuko Asada; Morio Ueno; Munetoyo Toda; Asako Hiraga; Monty Montoya; Chie Sotozono; Shigeru Kinoshita; Junji Hamuro

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4927. doi:

ARVO Annual Meeting Abstract September 2016

Metabolic plasticity in the cell-state homeostasis and differentiation of cultured human corneal endothelial cells

Junji Hamuro; Morio Ueno; Kazuko Asada; Munetoyo Toda; Monty Montoya; Chie Sotozono; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5278. doi:

ARVO Annual Meeting Abstract September 2016

The cell homogeneity is indispensable for regenerative medicine by cultivated human corneal endothelial cells

Munetoyo Toda; Morio Ueno; Asako Hiraga; Kazuko Asada; Monty Montoya; Chie Sotozono; Junji Hamuro; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5281. doi:

Cornea September 2016

Cell Homogeneity Indispensable for Regenerative Medicine by Cultured Human Corneal Endothelial Cells

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Junji Hamuro; Munetoyo Toda; Kazuko Asada; Asako Hiraga; Ursula Schlötzer-Schrehardt; Monty Montoya; Chie Sotozono; Morio Ueno; Shigeru Kinoshita
TAGS: cd44 antigens, cornea, donors, endothelial cells, homing-associated cell adhesion molecule, homogeneity, patient simulation, regenerative medicine, small patella syndrome, sodium polystyrene sulfonate
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4749-4761. doi: https://doi.org/10.1167/iovs.16-19770

Cornea August 2016

Metabolic Plasticity in Cell State Homeostasis and Differentiation of Cultured Human Corneal Endothelial Cells

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Junji Hamuro; Morio Ueno; Kazuko Asada; Munetoyo Toda; Monty Montoya; Chie Sotozono; Shigeru Kinoshita
TAGS: cd44 antigens, cornea, endothelial cells, glucose, homeostasis, metabolites, patient simulation, small patella syndrome, sodium polystyrene sulfonate, starvation
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4452-4463. doi: https://doi.org/10.1167/iovs.16-19807

Cornea August 2016

Concomitant Evaluation of a Panel of Exosome Proteins and MiRs for Qualification of Cultured Human Corneal Endothelial Cells

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Morio Ueno; Kazuko Asada; Munetoyo Toda; Kazue Nagata; Chie Sotozono; Nobuyoshi Kosaka; Takahiro Ochiya; Shigeru Kinoshita; Junji Hamuro
TAGS: cd44 antigens, cornea, endothelial cells, exosomes, homing-associated cell adhesion molecule, proteins, micrornas, donors
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4393-4402. doi: https://doi.org/10.1167/iovs.16-19805

Cornea August 2016

Gene Signature–Based Development of ELISA Assays for Reproducible Qualification of Cultured Human Corneal Endothelial Cells

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Morio Ueno; Kazuko Asada; Munetoyo Toda; Ursula Schlötzer-Schrehardt; Kazue Nagata; Monty Montoya; Chie Sotozono; Shigeru Kinoshita; Junji Hamuro
TAGS: cornea, cytokine, endothelial cells, enzyme-linked immunosorbent assay, gene expression profiling, genes, micrornas, polymerase chain reaction, small patella syndrome, sodium polystyrene sulfonate
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4295-4305. doi: https://doi.org/10.1167/iovs.16-19806

ARVO Annual Meeting Abstract June 2015

The different binding properties of cultured human corneal endothelial cell subpopulations to Descemet’s membrane components

Munetoyo Toda; Morio Ueno; Asako Hiraga; Kazuko Asada; Takahiro Nakamura; Michio Hagiya; Naoki Okumura; Noriko Koizumi; Junji Hamuro; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1144. doi:

ARVO Annual Meeting Abstract June 2015

Analysis of cytokines in serum and aqueous humor in patients with bullous keratopath

Morio Ueno; Munetoyo Toda; Asako Hiraga; Naomi Tobita; Hiroko Nakagawa; Chie Sotozono; Noriko Koizumi; Kazuko Asada; Junji Hamuro; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4018. doi:

ARVO Annual Meeting Abstract April 2014

Distinct energy metabolism between cultured mature human corneal endothelial cells and their phenotype transitioned cells

Kazuko Asada; Munetoyo Toda; Morio Ueno; Michiko Ujihara; Atsushi Mukai; Michio Hagiya; Naoki Okumura; Noriko Koizumi; Junji Hamuro; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2052. doi:

ARVO Annual Meeting Abstract April 2014

Identification of differentiated mature cultured human corneal endothelial cells and their distinct cell propensity from other immature subpopulations

Munetoyo Toda; Morio Ueno; Michiko Ujihara; Kazuko Asada; Michio Hagiya; Takahiro Nakamura; Naoki Okumura; Noriko Koizumi; Junji Hamuro; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2073. doi:

ARVO Annual Meeting Abstract April 2014

The integral analysis of senescence-associated secretory pathway and microRNA secretion of cultured human corneal endothelial cells relating to their functions, cell senescence, and epithelial-mesenchymal transition

Morio Ueno; Kazuko Asada; Munetoyo Toda; Michio Hagiya; Naoki Okumura; Noriko Koizumi; Junji Hamuro; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2076. doi:

ARVO Annual Meeting Abstract June 2013

Proliferation Propensity of Cultured Human Corneal Endothelial Cells and Their Plasticity Dictated by Culture Microenvironments

Munetoyo Toda; Kana Nakata; kazuko asada; Michio Hagiya; Morio Ueno; Naoki Okumura; Noriko Koizumi; Junji Hamuro; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1691. doi:

ARVO Annual Meeting Abstract June 2013

Integral Analysis of Gene Signatures and MicroRNA Expression of Cultured Human Corneal Endothelial Cells in Relation to Their Functions, Cell Senescence, Epithelial-Mesenchymal Transition, and Fibrosis

Kazuko Asada; Munetoyo Toda; Michio Hagiya; Kana Nakata; Morio Ueno; Naoki Okumura; Noriko Koizumi; Junji Hamuro; Shigeru Kinoshita

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3227. doi:

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Repressed miR-34a Expression Dictates the Cell Fate to Corneal Endothelium Failure

Mitochondria as platforms for dictating differentiation/maturation of human corneal endothelial cells with distinct energy metabolism and metabolomic signatures

Production of Homogeneous Cultured Human Corneal Endothelial Cells Indispensable for Innovative Cell Therapy

MicroRNA Profiles Qualify Phenotypic Features of Cultured Human Corneal Endothelial Cells

Profiles of cytokines in the aqueous humor and serum of bullous keratopathy patients

Regulation of mitochondrial respiration under cell culture stress in human corneal endothelial cells

The role of dysregulated expression of miRs in the pathogenesis of bullous keratopathy and Fuchs’ endothelial corneal dystrophy

Metabolic plasticity in the cell-state homeostasis and differentiation of cultured human corneal endothelial cells

The cell homogeneity is indispensable for regenerative medicine by cultivated human corneal endothelial cells

Cell Homogeneity Indispensable for Regenerative Medicine by Cultured Human Corneal Endothelial Cells

Metabolic Plasticity in Cell State Homeostasis and Differentiation of Cultured Human Corneal Endothelial Cells

Concomitant Evaluation of a Panel of Exosome Proteins and MiRs for Qualification of Cultured Human Corneal Endothelial Cells

Gene Signature–Based Development of ELISA Assays for Reproducible Qualification of Cultured Human Corneal Endothelial Cells

The different binding properties of cultured human corneal endothelial cell subpopulations to Descemet’s membrane components

Analysis of cytokines in serum and aqueous humor in patients with bullous keratopath

Distinct energy metabolism between cultured mature human corneal endothelial cells and their phenotype transitioned cells

Identification of differentiated mature cultured human corneal endothelial cells and their distinct cell propensity from other immature subpopulations

The integral analysis of senescence-associated secretory pathway and microRNA secretion of cultured human corneal endothelial cells relating to their functions, cell senescence, and epithelial-mesenchymal transition

Proliferation Propensity of Cultured Human Corneal Endothelial Cells and Their Plasticity Dictated by Culture Microenvironments

Integral Analysis of Gene Signatures and MicroRNA Expression of Cultured Human Corneal Endothelial Cells in Relation to Their Functions, Cell Senescence, Epithelial-Mesenchymal Transition, and Fibrosis

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