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ARVO Annual Meeting Abstract June 2022

Transcriptomic and metabolomic analyses of Fuchs endothelial corneal dystrophy and bullous keratopathy

Takefumi Yamaguchi; Yukari Yagi-Yaguchi; Takanori Suzuki; Hirotsugu Kasamatsu; Kazunari Higa; Masahiro Sugimoto; Hisashi Noma; Jun Shimazaki

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2279. doi:

Articles September 2021

Aqueous Cytokine Levels Are Associated With Progression of Peripheral Anterior Synechiae After Descemet Stripping Automated Endothelial Keratoplasty

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Yuki Kusano; Takefumi Yamaguchi; Sota Nishisako; Takehiro Matsumura; Masaki Fukui; Kazunari Higa; Toshihiro Inoue; Jun Shimazaki
TAGS: cytokine, descemet stripping endothelial keratoplasty, isolated tumor cells, peripheral anterior synechiae, protein measurement, total, eye
Trans. Vis. Sci. Tech.. 2021; 10(11):12. doi: https://doi.org/10.1167/tvst.10.11.12

Includes: Supplemental Content

Cornea September 2019

Effects of Amniotic Membrane–Derived Fibroblast Supernatant on Corneal Epithelium

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Kazunari Higa; Junko Higuchi; Reona Kimoto; Yoshiyuki Satake; Takefumi Yamaguchi; Daisuke Tomida; Jun Shimazaki
TAGS: amnion, cornea, corneal epithelium, epithelium, fibroblasts, wound healing, oryctolagus cuniculus, antibodies, flow cytometry
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3718-3726. doi: https://doi.org/10.1167/iovs.19-27041

ARVO Annual Meeting Abstract July 2019

Preoperative cytokine levels in aqueous humor and prognosis of corneal transplantation in bullous keratopathy following glaucoma filtration surgery

Takefumi Yamaguchi; Kazunari Higa; Yukari Yagi-Yaguchi; Daisuke Tomida; Jun Shimazaki

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3816. doi:

ARVO Annual Meeting Abstract July 2019

Human limbal organoid transplantation in a rabbit limbal deficiency model

Kazunari Higa; Junko Higuchi; Reona Kimono; Hideyuki Miyashita; Jun Shimazaki; Kazuo Tsubota; Shigeto Shimmura

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4129. doi:

Articles November 2018

Comparison of Artificial Anterior Chamber Internal Pressures and Cutting Systems for Descemet's Stripping Automated Endothelial Keratoplasty

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Sota Nishisako; Dai Aoki; Chiaki Sasaki; Kazunari Higa; Jun Shimazaki
TAGS: anterior chamber of eye, cornea, donors, endothelial cells, endothelium, keratoplasty, pressure-physical agent, tissue transplants, descemet stripping endothelial keratoplasty, significance
Trans. Vis. Sci. Tech.. 2018; 7(6):11. doi: https://doi.org/10.1167/tvst.7.6.11

ARVO Annual Meeting Abstract July 2018

Long-term Outcomes of Cultivated Epithelial Sheet Transplantation for Chemical or Thermal Burns of the Cornea

Jun Shimazaki; Kazunari Higa; Yoshiyuki Satake

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2278. doi:

ARVO Annual Meeting Abstract July 2018

Proteomic analysis of the aqueous humor: Complement activation is the major pathway in the Aqueous humor in eyes with complicated pseudophakic bullous keratopathy

Takefumi Yamaguchi; Koji Ueda; Kazunari Higa; Yoshiyuki Satake; Kazuo Tsubota; Jun Shimazaki

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2905. doi:

ARVO Annual Meeting Abstract July 2018

Effects of amniotic membrane mesenchymal stem cells for the corneal epithelial proliferation and differentiation

Kazunari Higa; Junk Higuchi; Yoshiyuki Satake; Takefumi Yamaguchi; Daisuke Tomida; Jun Shimazaki

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4356. doi:

Cornea March 2018

The Role of 2% Rebamipide Eye Drops Related to Conjunctival Differentiation in Superoxide Dismutase-1 ( Sod1 ) Knockout Mice

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Takashi Kojima; Cem Simsek; Ayako Igarashi; Kazue Aoki; Kazunari Higa; Takahiko Shimizu; Murat Dogru; Kazuo Tsubota; Jun Shimazaki
TAGS: conjunctiva, eyedrops, mice, rebamipide, sod1 gene, superoxide dismutase 1, rna, messenger, epithelium, mice, knockout, goblet cells
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1675-1681. doi: https://doi.org/10.1167/iovs.17-23213

Cornea February 2018

Preoperative Aqueous Cytokine Levels are Associated With Endothelial Cell Loss After Descemet's Stripping Automated Endothelial Keratoplasty

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Hiroyuki Yazu; Takefumi Yamaguchi; Naohiko Aketa; Kazunari Higa; Terumasa Suzuki; Yukari Yagi-Yaguchi; Yoshiyuki Satake; Takayuki Abe; Kazuo Tsubota; Jun Shimazaki
TAGS: cytokine, descemet stripping endothelial keratoplasty, endothelial cells, keratoplasty, preoperative care, postoperative care, endothelium, proteins
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):612-620. doi: https://doi.org/10.1167/iovs.17-23049

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Elevated aqueous inflammatory cytokine levels in eyes with ocular surface disease

Naohiko Nakayama; Takefumi Yamaguchi; Yukari Yagi-Yaguchi; Terumasa Suzuki; Kazunari Higa; Daisuke Tomida; Koji Kakisu; Seika Den; Yoshiyuki Satake; Jun Shimazaki

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):984. doi:

ARVO Annual Meeting Abstract June 2017

Elevation of aqueous IL-12 and IFNγ is associated with progressive endothelial cell loss after penetrating keratoplasty

Takefumi Yamaguchi; Terumasa Suzuki; Kazunari Higa; Naohiko Nakayama; Yukari Yagi-Yaguchi; Yoshiyuki Satake; Jun Shimazaki

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3794. doi:

Special Issue May 2017

Iris Damage Is Associated With Elevated Cytokine Levels in Aqueous Humor

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Naohiko Aketa; Takefumi Yamaguchi; Terumasa Suzuki; Kazunari Higa; Yukari Yagi-Yaguchi; Yoshiyuki Satake; Kazuo Tsubota; Jun Shimazaki
TAGS: cytokine, immune reconstitution inflammatory syndrome, iris, proteins, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO42-BIO51. doi: https://doi.org/10.1167/iovs.17-21421

Includes: Supplemental Content

Cornea November 2016

Elevated Cytokine Levels in the Aqueous Humor of Eyes With Bullous Keratopathy and Low Endothelial Cell Density

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Takefumi Yamaguchi; Kazunari Higa; Terumasa Suzuki; Naohiko Nakayama; Yukari Yagi-Yaguchi; Murat Dogru; Yoshiyuki Satake; Jun Shimazaki
TAGS: aqueous humor, cytokine, eye, endothelial cells, bullous keratopathy, proteins
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):5954-5962. doi: https://doi.org/10.1167/iovs.16-20187

ARVO Annual Meeting Abstract September 2016

The effect of 3% diquafosol sodium eye drops on the meibomian gland alterations of the superoxide dismutase-1 knockout mice

Keisuke Ikeda; Murat Dogru; Motoko Kawashima; Takashi Kojima; Kazunari Higa; Ayako Igarashi; Takefumi Yamaguchi; Seika Den-Shimazaki; Kazuo Tsubota; Jun Shimazaki

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2869. doi:

ARVO Annual Meeting Abstract September 2016

Rebamipide enhances the barrier function of human conjunctival epithelium

Yoshiyuki Satake; Kazunari Higa; Murat Dogru; Takefumi Yamaguchi; Jun Shimazaki

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3507. doi:

ARVO Annual Meeting Abstract September 2016

Spheroidal cultivation of the human limbal epithelial niche from small limbal tissue

Kazunari Higa; Hideyuki Miyashita; Jun Shimazaki; Kazuo Tsubota; Shigeto Shimmura

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4345. doi:

ARVO Annual Meeting Abstract September 2016

Neurogenic Homeostasis of Corneal Immunity; Peripheral Nerve Regulates Innate Immunity through Vasoactive Intestinal Peptide

Takefumi Yamaguchi; Kazunari Higa; Murat Dogru; Yoshiyuki Satake; Jun Shimazaki

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):335. doi:

ARVO Annual Meeting Abstract June 2015

Functional analysis of tissue engineered corneal endothelium from human skin derived precursors.

Emi Inagaki; Shin Hatou; Kazunari Higa; Hideyuki Miyashita; Satoru Yoshida; Kazuo Tsubota; Shigeto Shimmura

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3450. doi:

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Transcriptomic and metabolomic analyses of Fuchs endothelial corneal dystrophy and bullous keratopathy

Aqueous Cytokine Levels Are Associated With Progression of Peripheral Anterior Synechiae After Descemet Stripping Automated Endothelial Keratoplasty

Effects of Amniotic Membrane–Derived Fibroblast Supernatant on Corneal Epithelium

Preoperative cytokine levels in aqueous humor and prognosis of corneal transplantation in bullous keratopathy following glaucoma filtration surgery

Human limbal organoid transplantation in a rabbit limbal deficiency model

Comparison of Artificial Anterior Chamber Internal Pressures and Cutting Systems for Descemet's Stripping Automated Endothelial Keratoplasty

Long-term Outcomes of Cultivated Epithelial Sheet Transplantation for Chemical or Thermal Burns of the Cornea

Proteomic analysis of the aqueous humor: Complement activation is the major pathway in the Aqueous humor in eyes with complicated pseudophakic bullous keratopathy

Effects of amniotic membrane mesenchymal stem cells for the corneal epithelial proliferation and differentiation

The Role of 2% Rebamipide Eye Drops Related to Conjunctival Differentiation in Superoxide Dismutase-1 ( Sod1 ) Knockout Mice

Preoperative Aqueous Cytokine Levels are Associated With Endothelial Cell Loss After Descemet's Stripping Automated Endothelial Keratoplasty

Elevated aqueous inflammatory cytokine levels in eyes with ocular surface disease

Elevation of aqueous IL-12 and IFNγ is associated with progressive endothelial cell loss after penetrating keratoplasty

Iris Damage Is Associated With Elevated Cytokine Levels in Aqueous Humor

Elevated Cytokine Levels in the Aqueous Humor of Eyes With Bullous Keratopathy and Low Endothelial Cell Density

The effect of 3% diquafosol sodium eye drops on the meibomian gland alterations of the superoxide dismutase-1 knockout mice

Rebamipide enhances the barrier function of human conjunctival epithelium

Spheroidal cultivation of the human limbal epithelial niche from small limbal tissue

Neurogenic Homeostasis of Corneal Immunity; Peripheral Nerve Regulates Innate Immunity through Vasoactive Intestinal Peptide

Functional analysis of tissue engineered corneal endothelium from human skin derived precursors.

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