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Meeting Abstract (7)
Journal Articles (5)

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Investigative Ophthalmology & Visual Science (12)

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ARVO Annual Meeting Abstract (7)
Physiology and Pharmacology (3)
Cornea (1)
Retina (1)

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Eye Anatomy and Disorders (3)
External Eye Disease (2)
Genetics (2)
Biochemistry and Molecular Biology (1)
Cornea (1)
Glaucoma (1)
Immunology and Microbiology (1)
Pharmacology (1)
Retina (1)

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proteins (3)
agonists (2)
diabetes mellitus (2)
dry eye syndromes (2)
glucocorticoid receptors (2)
rats (2)
retina (2)
anti-inflammatory agents (1)
antioxidants (1)
atropine (1)

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ARVO Annual Meeting Abstract June 2024

SCO-116 exhibits potent, selective activation of NRF2 suitable for use in treatment of ocular diseases

Ralph Henry; Dave Flory; Brooks Gentry; Yuko Katayama; Ryokichi Koyama; Shigemitsu Matsumoto; Yasuke Moritoh; Misty Stevens; Masanori Watanabe; Keith Ward

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):195.

ARVO Annual Meeting Abstract June 2024

SCO-116 protects retinal pigment epithelium from oxidative insult in vitro and preserves visual function and retinal structure in sodium iodate-induced geographic atrophy in rats in vivo

Keith W Ward; Rafal Farjo; Dave Flory; Brooks Gentry; Ralph Henry; Didier Nuno; Misty Stevens; Phillip Vanlandingham

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1929.

ARVO Annual Meeting Abstract June 2024

SCO-116, a novel small-molecule NRF2 activator, potently induces NQO1 in multiple rabbit ocular tissues

Misty Stevens; Brooks Gentry; Dave Flory; Ralph Henry; Brett Schneider; Keith W Ward

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4177.

Retina February 2018

Nrf2 Activation Is a Potential Therapeutic Approach to Attenuate Diabetic Retinopathy

PDF

Devy Deliyanti; Saeed F. Alrashdi; Sih Min Tan; Colin Meyer; Keith W. Ward; Judy B. de Haan; Jennifer L. Wilkinson-Berka
TAGS: antioxidants, attenuation, diabetes mellitus, diabetic retinopathy, retina, rats, oxidative stress, hyperglycemia, proteins
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):815-825. https://doi.org/10.1167/iovs.17-22920

Cornea March 2012

Correlation of Tear Inflammatory Cytokines and Matrix Metalloproteinases with Four Dry Eye Diagnostic Tests

PDF

Karl R. VanDerMeid; Stephanie P. Su; Keith W. Ward; Jin-Zhong Zhang
TAGS: cytokine, diagnostic techniques and procedures, dry eye syndromes, matrix metalloproteinases
Invest. Ophthalmol. Vis. Sci.. 2012; 53(3):1512-1518. https://doi.org/10.1167/iovs.11-7627

ARVO Annual Meeting Abstract April 2011

Anti-Allergic Effects of Mapracorat, a Novel Selective Glucocorticoid Receptor Agonist, in Human Conjunctival Fibroblasts and Epithelial Cells

Megan E. Cavet; Stepan M. Volhejn; Karen L. Harrington; Thomas Vollmer; Keith W. Ward; Jin-Zhong Zhang

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):6422.

ARVO Annual Meeting Abstract April 2011

Effect Of Polyhexamethylene Biguanide On Human Corneal Epithelial Barrier Function

Jin-Zhong Zhang; Karl R. VanDerMeid; Karen L. Harrington; Megan E. Cavet; Keith W. Ward

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):291.

ARVO Annual Meeting Abstract April 2011

Anti-Inflammatory And Anti-Oxidant Effects Of The Green Tea Polyphenol Epigallocatechin Gallate In Human Corneal Epithelial Cells

Karen L. Harrington; Megan E. Cavet; Thomas R. Vollmer; Stepan M. Volhejn; Jessica E. Ackerman; Keith W. Ward; Jin-Zhong Zhang

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):311.

ARVO Annual Meeting Abstract April 2011

Correlation Of Cytokine And Matrix Metalloproteinase Levels In Human Tear Samples Collected By Schirmer Strips With Tear Osmolarity

Karl VanDerMeid; Stephanie P. Su; Kathleen L. Krenzer; Keith W. Ward; Jin-Zhong Zhang

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):408.

Physiology and Pharmacology March 2011

In Vivo Ocular Efficacy Profile of Mapracorat, a Novel Selective Glucocorticoid Receptor Agonist, in Rabbit Models of Ocular Disease

PDF

Afshin Shafiee; Claudio Bucolo; Ewa Budzynski; Keith W. Ward; Francisco J. López
TAGS: agonists, anti-inflammatory agents, dry eye syndromes, eye, eye diseases, glucocorticoid receptors, intraocular pressure, oryctolagus cuniculus, paracentesis, atropine
Invest. Ophthalmol. Vis. Sci.. 2011; 52(3):1422-1430. https://doi.org/10.1167/iovs.10-5598

Physiology and Pharmacology January 2010

Reduced Myocilin Expression in Cultured Monkey Trabecular Meshwork Cells Induced by a Selective Glucocorticoid Receptor Agonist: Comparison with Steroids

PDF

Bruce A. Pfeffer; Charu A. DeWitt; Mercedes Salvador-Silva; Megan E. Cavet; Francisco J. López; Keith W. Ward
TAGS: agonists, cercopithecidae, glucocorticoid receptors, myoc gene, proteins, steroids, trabecular meshwork, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2010; 51(1):437-446. https://doi.org/10.1167/iovs.09-4202

Physiology and Pharmacology August 2009

Protective Effects of a Coumarin Derivative in Diabetic Rats

PDF

Claudio Bucolo; Keith W. Ward; Emanuela Mazzon; Salvatore Cuzzocrea; Filippo Drago
TAGS: coumarins, diabetes mellitus, intercellular adhesion molecule 1, rats, vascular endothelial growth factor a, nitric oxide synthase, streptozocin, proteins, cadherins, retina
Invest. Ophthalmol. Vis. Sci.. 2009; 50(8):3846-3852. https://doi.org/10.1167/iovs.08-3328

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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