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Lens December 2024

Disruption of the Enterococcus faecalis– Induced Biofilm on the Intraocular Lens Using Bacteriophages

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Tatsuma Kishimoto; Ken Fukuda; Waka Ishida; Aozora Kuwana; Daisuke Todokoro; Jumpei Uchiyama; Shigenobu Matsuzaki; Kenji Yamashiro
TAGS: bacteriophages, biofilms, intraocular lens implant device, vancomycin, enterococcus faecalis, bacteria, intraocular lens implantation procedure
Trans. Vis. Sci. Tech.. 2024; 13(12):25. https://doi.org/10.1167/tvst.13.12.25

ARVO Annual Meeting Abstract June 2024

Development of Allergic Conjunctival Disease Image Database and Diagnostic Support AI

Dai Miyazaki; Michiko Yonehara; Shin-ichi Sasaki; Yuji Nakagawa; Yuji Ayatsuka; Yuko Hara; Eisuke Shimizu; Ken Fukuda; Nobuyuki Ebihara; Takenori Inomata; Atsuki Fukushima; Hiroshi Fujishima; Tatsuya Mimura; Moeko Kawai; Eiichi Uchio; Kenichi Namba

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1961.

Articles April 2022

Intracameral Bacteriophage Injection as Postoperative Prophylaxis for Enterococcus faecalis –Induced Endophthalmitis After Cataract Surgery in Rabbits

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Tatsuma Kishimoto; Waka Ishida; Isana Nakajima; Takako Ujihara; Takashi Suzuki; Jumpei Uchiyama; Shigenobu Matsuzaki; Ken Fukuda
TAGS: bacteriophages, cataract surgery, endophthalmitis, injections, oryctolagus cuniculus, postoperative care, prevention, eye, enterococcus faecalis
Trans. Vis. Sci. Tech.. 2022; 11(4):2. https://doi.org/10.1167/tvst.11.4.2

ARVO Annual Meeting Abstract July 2019

Therapeutic effects of intravitreous bacteriophage on Enterococcus faecalis endophthalmitis in mice

Ken Fukuda; Tatsuma Kishimoto; Waka Ishida; Takashi Suzuki; Jumpei Uchiyama; Shigenobu Matsuzaki; Masanori Daibata; Atsuki Fukushima

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2539.

ARVO Annual Meeting Abstract July 2018

The interaction between dry eye disease and allergic conjunctivitis in mice

Tatsuma Kishimoto; Ken Fukuda; Waka Ishida; Atsuki Fukushima

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):120.

ARVO Annual Meeting Abstract September 2016

Prophylactic and therapeutic effects of oral administration of transgenic rice on birch pollen–induced allergic conjunctivitis in mice

Waka Ishida; Ken Fukuda; Lijun Yang; Fumio Takaiwa; Atsuki Fukushima

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3289.

ARVO Annual Meeting Abstract September 2016

Variable clinical course of cytomegalovirus anterior uveitis in Japanese patients

Yosuke Harada; Ken Fukuda; Asami Nakahira; Kentaro Tada; Tamaki Sumi; Atsuki Fukushima

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3296.

Cornea January 2016

Inhibition by the Antimicrobial Peptide LL37 of Lipopolysaccharide-Induced Innate Immune Responses in Human Corneal Fibroblasts

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Waka Ishida; Yosuke Harada; Ken Fukuda; Atsuki Fukushima
TAGS: cornea, fibroblasts, intercellular adhesion molecule 1, ll-37 peptide, antimicrobials, peptides, lipopolysaccharides, immune response, interleukin-6, interleukin-8
Invest. Ophthalmol. Vis. Sci.. 2016; 57(1):30-39. https://doi.org/10.1167/ iovs.15-17652

Cornea August 2015

Roles of Epithelial Cell–Derived Type 2–Initiating Cytokines in Experimental Allergic Conjunctivitis

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Yosuke Asada; Susumu Nakae; Waka Ishida; Kanji Hori; Jobu Sugita; Katsuko Sudo; Ken Fukuda; Atsuki Fukushima; Hajime Suto; Akira Murakami; Hirohisa Saito; Nobuyuki Ebihara; Akira Matsuda
TAGS: allergic conjunctivitis, body tissue, conjunctiva, cytokine, epithelial cells, interleukin-17e, mice, immunoglobulin e, rna, messenger, proteins
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5194-5202. https://doi.org/10.1167/iovs.15-16563

Includes: Supplemental Content

Cornea August 2013

Alarmins From Corneal Epithelial Cells Upregulate CCL11 and VCAM-1 in Corneal Fibroblasts

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Ken Fukuda; Waka Ishida; Hiroshi Tanaka; Yosuke Harada; Akira Matsuda; Nobuyuki Ebihara; Atsuki Fukushima
TAGS: cornea, cytokine, fibroblasts, necrosis, vascular cell adhesion molecule-1, corneal epithelial cells, interleukin-4, interleukin-13
Invest. Ophthalmol. Vis. Sci.. 2013; 54(8):5817-5823. https://doi.org/10.1167/iovs.13-11969

ARVO Annual Meeting Abstract June 2013

Alarmin from corneal epithelial cells synergizes with Th2 cytokines on the expression of CCL11 and VCAM-1 by corneal fibroblasts

Ken Fukuda; Hiroshi Tanaka; Waka Ishida; Yosuke Harada; Tamaki Sumi; Akira Matsuda; Nobuyuki Ebihara; Atsuki Fukushima

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5244.

ARVO Annual Meeting Abstract June 2013

Protection of barrier function and anti-inflammatory effects of rebamipide in human corneal epithelial cells

Hiroshi Tanaka; Ken Fukuda; Waka Ishida; Yosuke Harada; Tamaki Sumi; Atsuki Fukushima

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):911.

ARVO Annual Meeting Abstract March 2012

Differentiation of Bone-Marrow Derived Cells into Non-Immunocompetent Corneal Cells

Yosuke Harada; Osamu Taguchi; Waka Ishida; Mina Kajisako; Ken Fukuda; Yoshiaki Kiuchi; Atsuki Fukushima

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1080.

ARVO Annual Meeting Abstract March 2012

Therapeutic Effects of Topical Bacteriophage KPP12 Administration on Pseudomonas aeruginosa Keratitis in Mice

Ken Fukuda; Waka Ishida; Jumpei Uchiyama; Tamae Morita; Yosuke Harada; Tamaki Sumi; Shigenobu Matsuzaki; Masanori Daibata; Atsuki Fukushima

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6201.

Immunology and Microbiology October 2011

Regulation of Experimental Autoimmune Uveoretinitis by Anti-Delta-Like Ligand 4 Monoclonal Antibody

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Waka Ishida; Ken Fukuda; Shuji Sakamoto; Noriko Koyama; Akemi Koyanagi; Hideo Yagita; Atsuki Fukushima
TAGS: autoimmune diseases, autoimmunity, cytokine, eye, ligands, mice, monoclonal antibodies, rna, messenger, interleukin-17, regulation
Invest. Ophthalmol. Vis. Sci.. 2011; 52(11):8224-8230. https://doi.org/10.1167/iovs.11-7756

Immunology and Microbiology January 2011

Dynamic Changes of microRNAs in the Eye during the Development of Experimental Autoimmune Uveoretinitis

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Waka Ishida; Ken Fukuda; Takuma Higuchi; Mina Kajisako; Shuji Sakamoto; Atsuki Fukushima
TAGS: eye, micrornas, autoimmune diseases, mice, cytokine
Invest. Ophthalmol. Vis. Sci.. 2011; 52(1):611-617. https://doi.org/10.1167/iovs.10-6115

Cornea August 2010

Inhibition by Tranilast of the Cytokine-Induced Expression of Chemokines and the Adhesion Molecule VCAM-1 in Human Corneal Fibroblasts

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Tadafumi Adachi; Ken Fukuda; Yukiko Kondo; Teruo Nishida
TAGS: cell adhesion molecules, chemokines, cornea, cytokine, fibroblasts, tranilast, vascular cell adhesion molecule-1, tumor necrosis factors, interleukin-4
Invest. Ophthalmol. Vis. Sci.. 2010; 51(8):3954-3960. https://doi.org/10.1167/iovs.09-4161

Cornea November 2008

Inhibition by a Selective IκB Kinase-2 Inhibitor of Interleukin-1–Induced Collagen Degradation by Corneal Fibroblasts in Three-Dimensional Culture

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Yukiko Kondo; Ken Fukuda; Tadafumi Adachi; Teruo Nishida
TAGS: catabolism, collagen, cornea, fibroblasts, interleukin-1, phosphotransferases, dexamethasone, gel
Invest. Ophthalmol. Vis. Sci.. 2008; 49(11):4850-4857. https://doi.org/10.1167/iovs.08-1897

Cornea February 2008

Delayed Disruption of Barrier Function in Cultured Human Corneal Epithelial Cells Induced by Tumor Necrosis Factor-α in a Manner Dependent on NF-κB

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Kazuhiro Kimura; Shinichiro Teranishi; Ken Fukuda; Koji Kawamoto; Teruo Nishida
TAGS: corneal epithelial cells, curcumin, immunoblotting, tumor necrosis, tumor necrosis factors, fluorescent antibody technique, proteins, cytokine
Invest. Ophthalmol. Vis. Sci.. 2008; 49(2):565-571. https://doi.org/10.1167/iovs.07-0419

Clinical and Epidemiologic Research February 2007

Genetic Polymorphisms in the Promoter of the Interferon Gamma Receptor 1 Gene Are Associated with Atopic Cataracts

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Akira Matsuda; Nobuyuki Ebihara; Naoki Kumagai; Ken Fukuda; Koji Ebe; Koji Hirano; Chie Sotozono; Mamoru Tei; Koichi Hasegawa; Makiko Shimizu; Mayumi Tamari; Kenichi Namba; Shigeaki Ohno; Nobuhisa Mizuki; Zenro Ikezawa; Taro Shirakawa; Junji Hamuro; Shigeru Kinoshita
TAGS: cataract, genes, interferon type ii, polymorphism, single nucleotide polymorphism, polymerase chain reaction, genotype determination, genes, reporter
Invest. Ophthalmol. Vis. Sci.. 2007; 48(2):583-589. https://doi.org/10.1167/iovs.06-0991

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Disruption of the Enterococcus faecalis– Induced Biofilm on the Intraocular Lens Using Bacteriophages

Development of Allergic Conjunctival Disease Image Database and Diagnostic Support AI

Intracameral Bacteriophage Injection as Postoperative Prophylaxis for Enterococcus faecalis –Induced Endophthalmitis After Cataract Surgery in Rabbits

Therapeutic effects of intravitreous bacteriophage on Enterococcus faecalis endophthalmitis in mice

The interaction between dry eye disease and allergic conjunctivitis in mice

Prophylactic and therapeutic effects of oral administration of transgenic rice on birch pollen–induced allergic conjunctivitis in mice

Variable clinical course of cytomegalovirus anterior uveitis in Japanese patients

Inhibition by the Antimicrobial Peptide LL37 of Lipopolysaccharide-Induced Innate Immune Responses in Human Corneal Fibroblasts

Roles of Epithelial Cell–Derived Type 2–Initiating Cytokines in Experimental Allergic Conjunctivitis

Alarmins From Corneal Epithelial Cells Upregulate CCL11 and VCAM-1 in Corneal Fibroblasts

Alarmin from corneal epithelial cells synergizes with Th2 cytokines on the expression of CCL11 and VCAM-1 by corneal fibroblasts

Protection of barrier function and anti-inflammatory effects of rebamipide in human corneal epithelial cells

Differentiation of Bone-Marrow Derived Cells into Non-Immunocompetent Corneal Cells

Therapeutic Effects of Topical Bacteriophage KPP12 Administration on Pseudomonas aeruginosa Keratitis in Mice

Regulation of Experimental Autoimmune Uveoretinitis by Anti-Delta-Like Ligand 4 Monoclonal Antibody

Dynamic Changes of microRNAs in the Eye during the Development of Experimental Autoimmune Uveoretinitis

Inhibition by Tranilast of the Cytokine-Induced Expression of Chemokines and the Adhesion Molecule VCAM-1 in Human Corneal Fibroblasts

Inhibition by a Selective IκB Kinase-2 Inhibitor of Interleukin-1–Induced Collagen Degradation by Corneal Fibroblasts in Three-Dimensional Culture

Delayed Disruption of Barrier Function in Cultured Human Corneal Epithelial Cells Induced by Tumor Necrosis Factor-α in a Manner Dependent on NF-κB

Genetic Polymorphisms in the Promoter of the Interferon Gamma Receptor 1 Gene Are Associated with Atopic Cataracts

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