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Lens September 2020

Changes to Zonular Tension Alters the Subcellular Distribution of AQP5 in Regions of Influx and Efflux of Water in the Rat Lens

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Rosica S. Petrova; Nandini Bavana; Rusin Zhao; Kevin L. Schey; Paul J. Donaldson
TAGS: lens (device), lens, crystalline, tissue membrane, water
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):36. doi: https://doi.org/10.1167/iovs.61.11.36

ARVO Annual Meeting Abstract June 2020

Untargeted lipid profiling of retinal pigment epithelium (RPE) of human retina using LC-MS/MS and MALDI imaging mass spectrometry

Ankita Kotnala; David M.G. Anderson; Jarod A. Fincher; Nathan Heath Patterson; Lee S Cantrell; Jeffrey D. A. Curcio; Christine Curcio; Kevin L Schey

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1939. doi:

ARVO Annual Meeting Abstract June 2020

The role of autophagy and the nuclear excisosome in organelle degradation in lenses of three primate species

M Joseph Costello; Kurt O Gilliland; Ashik Mohamed; Kevin L Schey

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2299. doi:

ARVO Annual Meeting Abstract July 2019

Structural Characterization of Aquaporin-0 by Native and Hydrogen-Deuterium Exchange Mass Spectrometry

Kevin L Schey; Wendy L. White; Aryel E. Furman; Sophie R. Harvey; Yue Ju; Erin M. Panczyk; Vicki H. Wysocki

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4796. doi:

ARVO Annual Meeting Abstract July 2019

Characterization of aquaporin-5 protein-protein interactions, subcellular localization, and phosphorylation in the ocular lens

Romell Gletten; Rosica Petrova; Paul J Donaldson; Kevin L Schey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5685. doi:

ARVO Annual Meeting Abstract July 2019

Comparative Morphology of Lens Organelle-Free Zone Formation in Three Primate Species Supports the Role of the Nuclear Excisosome

M Joseph Costello; Kurt O Gilliland; Ashik Mohamed; Kevin L Schey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2233. doi:

ARVO Annual Meeting Abstract July 2019

Sample preparation effects on retina lipid analysis by MALDI imaging and LC-MS technologies.

Ankita Kotnala; David M G Anderson; Nathan Heath Patterson; Jeffery D Messinger; Christine Curcio; Kevin L Schey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2986. doi:

Lens November 2018

Proteomic Analysis of S-Palmitoylated Proteins in Ocular Lens Reveals Palmitoylation of AQP5 and MP20

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Zhen Wang; Kevin L. Schey
TAGS: cattle, lens (device), lens, crystalline, peptides, proteins, proteome, palmitates, gel
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5648-5658. doi: https://doi.org/10.1167/iovs.18-25312

ARVO Annual Meeting Abstract July 2018

High Resolution Imaging Mass Spectrometry of Human Donor Eyes with and without Age-Related Macular Degeneration (AMD)

David Anderson; Jerry Messinger; Nathan H Patterson; Jeffrey M Spraggins; Christine A. Curcio; Kevin L Schey

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3211. doi:

ARVO Annual Meeting Abstract July 2018

Imaging Mass Spectrometry of Age-Related Molecular Changes in the Ocular Lens

Kevin L Schey; David MG Anderson; Dhananjay Sakrikar; Jamie L Wenke; Md. Amir Hossen; Jeffrey M Spraggins

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3483. doi:

Visual Neuroscience January 2018

Optic Nerve Regeneration After Crush Remodels the Injury Site: Molecular Insights From Imaging Mass Spectrometry

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David T. Stark; David M. G. Anderson; Jacky M. K. Kwong; Nathan Heath Patterson; Kevin L. Schey; Richard M. Caprioli; Joseph Caprioli
TAGS: diagnostic imaging, lipids, mass spectrometry, optic nerve regeneration, wounds and injuries, optic nerve, hyperplasia, body tissue, gangliosides, sulfoglycosphingolipids
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):212-222. doi: https://doi.org/10.1167/iovs.17-22509

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Glutathione is Required for Ocular Surface Development

Ying Chen; Nicholas Apostolopoulos; David Orlicky; David M.G. Anderson; Kevin L Schey; David Thompson; Richard A Lang; Vasilis Vasiliou

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1724. doi:

ARVO Annual Meeting Abstract June 2017

Quantification of irreversible thioether GSH modification in human and guinea pig lens proteins

Kevin L Schey; Zhen Wang; Frank Joseph Giblin

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5597. doi:

Lens October 2016

Identification and Functional Assessment of Age-Dependent Truncations to Cx46 and Cx50 in the Human Lens

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Nefeli Slavi; Zhen Wang; Lucas Harvey; Kevin L. Schey; Miduturu Srinivas
TAGS: lens, crystalline, cytokinesis, lens (device), cytoplasm, gap junction protein
Invest. Ophthalmol. Vis. Sci.. 2016; 57(13):5714-5722. doi: https://doi.org/10.1167/iovs.16-19698

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Spatially-resolved proteomics by imaging mass spectrometry of ocular tissues

Kevin L Schey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Proteomic and Immunohistochemical Characterization of Lens Fiber Cell Vesicles

Romell Gletten; Zhen Wang; Kerry Walker; Angus C Grey; Paul J Donaldson; Kevin L Schey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3075. doi:

ARVO Annual Meeting Abstract September 2016

Qualitative and quantitative analysis of AQP5 modifications in lens fiber cells

Zhen Wang; Kevin L Schey

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Lens August 2016

Spatially Directed Proteomics of the Human Lens Outer Cortex Reveals an Intermediate Filament Switch Associated With the Remodeling Zone

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Jamie L. Wenke; W. Hayes McDonald; Kevin L. Schey
TAGS: intermediate filaments, lens, crystalline, proteins, proteomics, lens (device), tissue membrane, peptides
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4108-4114. doi: https://doi.org/10.1167/iovs.16-19791

Includes: Supplemental Content

Lens December 2015

Proteomic Analysis of Lipid Raft-Like Detergent-Resistant Membranes of Lens Fiber Cells

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Zhen Wang; Kevin L. Schey
TAGS: cholesterol, desmin-related myopathy, detergents, lens (device), lens, crystalline, lipid rafts, lipids, proteins, proteome, tissue membrane
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8349-8360. doi: https://doi.org/10.1167/iovs.15-18273

Includes: Supplemental Content

Lens November 2015

MALDI Imaging Mass Spectrometry Spatially Maps Age-Related Deamidation and Truncation of Human Lens Aquaporin-0

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Jamie L. Wenke; Kristie L. Rose; Jeffrey M. Spraggins; Kevin L. Schey
TAGS: diagnostic imaging, lens (device), lens, crystalline, mass spectrometry, peptides, spectrometry, mass, matrix-assisted laser desorption-ionization, water channels, proteins, maps
Invest. Ophthalmol. Vis. Sci.. 2015; 56(12):7398-7405. doi: https://doi.org/10.1167/iovs.15-18117

Includes: Supplemental Content

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Changes to Zonular Tension Alters the Subcellular Distribution of AQP5 in Regions of Influx and Efflux of Water in the Rat Lens

Untargeted lipid profiling of retinal pigment epithelium (RPE) of human retina using LC-MS/MS and MALDI imaging mass spectrometry

The role of autophagy and the nuclear excisosome in organelle degradation in lenses of three primate species

Structural Characterization of Aquaporin-0 by Native and Hydrogen-Deuterium Exchange Mass Spectrometry

Characterization of aquaporin-5 protein-protein interactions, subcellular localization, and phosphorylation in the ocular lens

Comparative Morphology of Lens Organelle-Free Zone Formation in Three Primate Species Supports the Role of the Nuclear Excisosome

Sample preparation effects on retina lipid analysis by MALDI imaging and LC-MS technologies.

Proteomic Analysis of S-Palmitoylated Proteins in Ocular Lens Reveals Palmitoylation of AQP5 and MP20

High Resolution Imaging Mass Spectrometry of Human Donor Eyes with and without Age-Related Macular Degeneration (AMD)

Imaging Mass Spectrometry of Age-Related Molecular Changes in the Ocular Lens

Optic Nerve Regeneration After Crush Remodels the Injury Site: Molecular Insights From Imaging Mass Spectrometry

Glutathione is Required for Ocular Surface Development

Quantification of irreversible thioether GSH modification in human and guinea pig lens proteins

Identification and Functional Assessment of Age-Dependent Truncations to Cx46 and Cx50 in the Human Lens

Spatially-resolved proteomics by imaging mass spectrometry of ocular tissues

Proteomic and Immunohistochemical Characterization of Lens Fiber Cell Vesicles

Qualitative and quantitative analysis of AQP5 modifications in lens fiber cells

Spatially Directed Proteomics of the Human Lens Outer Cortex Reveals an Intermediate Filament Switch Associated With the Remodeling Zone

Proteomic Analysis of Lipid Raft-Like Detergent-Resistant Membranes of Lens Fiber Cells

MALDI Imaging Mass Spectrometry Spatially Maps Age-Related Deamidation and Truncation of Human Lens Aquaporin-0

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