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ARVO Annual Meeting Abstract June 2022

Pharmacological chaperones improve rhodopsin homeostasis and protects photoreceptors in the RHO P23H mouse model of retinitis pigmentosa

Abhishek Vats; Yibo Xi; Bing Feng; Owen Clinger; Xujie Liu; Archisha Ghosh; Anthony St. Leger; Kira L Lathrop; Gregory Tochtrop; Serge Picaud; Yuanyuan Chen

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):681 – F0135. doi:

ARVO Annual Meeting Abstract June 2021

A non-retinoid chaperone of rhodopsin protects the Rho P23H/+ mouse retina in ex vivo culture.

Abhishek Vats; Bing Feng; Owen Clinger; Mark Schurdak; Kira Lathrop; Gregory P Tochtrop; Yuanyuan Chen

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3160. doi:

ARVO Annual Meeting Abstract June 2020

VEGF produced by CD4 + T cells and macrophages contributes to HSV-1 mediated ocular pathology by inducing sympathetic hyperinnervation of the cornea

Hongmin Yun; Kira L Lathrop; Michael Yee; Robert Hendricks; Anthony St. Leger

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5153. doi:

ARVO Annual Meeting Abstract July 2019

Inside and out: the roles of a stress response-cytolysin in corneal epithelial cell damage and intrastromal inflammation

Robert M Q Shanks; Kimberly Brothers; Nicholas A Stella; Kira L Lathrop; Eric G Romanowski; Regis P Kowalski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6412. doi:

Glaucoma October 2018

Structure–Function Changes of the Porcine Distal Outflow Tract in Response to Nitric Oxide

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Susannah Waxman; Chao Wang; Yalong Dang; Ying Hong; Hamed Esfandiari; Priyal Shah; Kira L. Lathrop; Ralitsa T. Loewen; Nils A. Loewen
TAGS: endothelin-1, ng-nitroarginine methyl ester, nitric oxide, spectral domain-optical coherence tomography, suidae, eye, deet, perfusion, dilatation, pathologic
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4886-4895. doi: https://doi.org/10.1167/iovs.18-24943

Includes: Supplemental Content

Glaucoma October 2018

Radial and Circumferential Collagen Fibers Are a Feature of the Peripapillary Sclera of Human, Monkey, Pig, Cow, Goat, and Sheep

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Alexandra Gogola; Ning-Jiun Jan; Kira L. Lathrop; Ian A. Sigal
TAGS: cattle, cercopithecidae, collagen, eye, galveston orientation and amnesia test, mammals, sclera, sheep
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4763-4774. doi: https://doi.org/10.1167/iovs.18-25025

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Retinochoroidal Blood Flow is Demonstrated in an Orthotopic Vascularized Whole Eye Transplant Model

Maxine R Miller; Jila Noori; Touka Banaee; Yong Wang; Chiaki Komatsu; Bing Li; Wendy Chen; Kira L Lathrop; Joshua Barnett; Joel S Schuman; Wensheng Zhang; Mario G. Solari; José-Alain Sahel; Andrew W Eller; Kia M. Washington

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4999. doi:

Glaucoma June 2018

Spatial Patterns and Age-Related Changes of the Collagen Crimp in the Human Cornea and Sclera

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Alexandra Gogola; Ning-Jiun Jan; Bryn Brazile; Po Lam; Kira L. Lathrop; Kevin C. Chan; Ian A. Sigal
TAGS: collagen, cornea, eye, sclera
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2987-2998. doi: https://doi.org/10.1167/iovs.17-23474

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Collagen architecture in the third dimension:3D polarized light microscopy (3DPLM) for mapping in-plane (IP) and out-of-plane (OOP) collagen fiber architecture

Bin Yang; Ning-Jiun Jan; Po Lam; Kira L Lathrop; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4825. doi:

ARVO Annual Meeting Abstract June 2017

Rapid learning curve assessment in an ex vivo training system for microincisional glaucoma surgery

CHAO WANG; Yalong Dang; Susannah Waxman; Hardik Parikh; Igor I Bussel; Ralitsa Loewen; Xiaobo Xia; Kira L Lathrop; Richard Anthony Bilonick; Nils Loewen

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4929. doi:

ARVO Annual Meeting Abstract June 2017

Stretch-Induced Collagen Bundle Uncrimping and Recruitment are Independent of Depth in Equatorial Sclera

Jacob Wallace; Ning-Jiun Jan; Alexandra Gogola; Michael Iasella; Kira L Lathrop; Andrew P Voorhees; Huong Tran; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3162. doi:

ARVO Annual Meeting Abstract June 2017

Between a basket and a finger trap: a unified model of posterior pole fiber architecture

Ian A Sigal; Ning-Jiun Jan; Kira L Lathrop; Andrew P Voorhees

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3161. doi:

Multidisciplinary Ophthalmic Imaging February 2017

Collagen Architecture of the Posterior Pole: High-Resolution Wide Field of View Visualization and Analysis Using Polarized Light Microscopy

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Ning-Jiun Jan; Kira Lathrop; Ian A. Sigal
TAGS: collagen, microscopy, polarization, sclera
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):735-744. doi: https://doi.org/10.1167/iovs.16-20772

ARVO Annual Meeting Abstract September 2016

Visualization and Quantification of Outflow after Ab Interno Trabeculectomy and Trabecular Micro-Bypass Stents using Differential Canalograms

Hardik Parikh; Ralitsa Loewen; Pritha Sengupta; Joel S Schuman; Kira L Lathrop; Nils A Loewen

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6508. doi:

ARVO Annual Meeting Abstract September 2016

Novel method reveals heterogeneous micro-scale response of sclera collagen bundles to homogeneous macro-scale stretch

Ning-Jiun Jan; Michael Iasella; Mason Lester; Danielle Hu; Kira L Lathrop; Andrew P Voorhees; Huong Tran; Gadi Wollstein; Joel S Schuman; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3566. doi:

ARVO Annual Meeting Abstract September 2016

Age-related changes in anterograde transport, axonal integrity and visuomotor function in DBA/2J and C57BL/6J mice

Xiaoling Yang; Yolandi van der Merwe; Leon C Ho; Ian P Conner; Kira L Lathrop; Gadi Wollstein; Joel S Schuman; Kevin C Chan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5144. doi:

ARVO Annual Meeting Abstract September 2016

Identifying the Palisades of Vogt in Human Ex-vivo Tissue

Kira L Lathrop; Jessica F. Steele; Scott P. Drexler; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):900. doi:

Cornea April 2016

A Central Role for Sympathetic Nerves in Herpes Stromal Keratitis in Mice

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Hongmin Yun; Kira L. Lathrop; Robert L. Hendricks
TAGS: cornea, corneal stroma, mice, simplexvirus, stromal keratitis, sympathetic nerve, neurons, sensory nerves, nerve fibers, persistence
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1749-1756. doi: https://doi.org/10.1167/iovs.16-19183

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Ex-vivo remodeling of palisades of Vogt in preserved tissue

Kira L Lathrop; Jessica F Steele; Virender S Sangwan; Sayan Basu; Swapna Shanbhag; cornea

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3465. doi:

ARVO Annual Meeting Abstract April 2014

Collagen Crimp Period in the Corneoscleral Shell

Ning-Jiun Jan; Jonathan L Grimm; Bo Wang; Kira L Lathrop; Huong Tran; Gadi Wollstein; Larry Kagemann; Hiroshi Ishikawa; Joel S Schuman; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3715. doi:

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Pharmacological chaperones improve rhodopsin homeostasis and protects photoreceptors in the RHO P23H mouse model of retinitis pigmentosa

A non-retinoid chaperone of rhodopsin protects the Rho P23H/+ mouse retina in ex vivo culture.

VEGF produced by CD4 + T cells and macrophages contributes to HSV-1 mediated ocular pathology by inducing sympathetic hyperinnervation of the cornea

Inside and out: the roles of a stress response-cytolysin in corneal epithelial cell damage and intrastromal inflammation

Structure–Function Changes of the Porcine Distal Outflow Tract in Response to Nitric Oxide

Radial and Circumferential Collagen Fibers Are a Feature of the Peripapillary Sclera of Human, Monkey, Pig, Cow, Goat, and Sheep

Retinochoroidal Blood Flow is Demonstrated in an Orthotopic Vascularized Whole Eye Transplant Model

Spatial Patterns and Age-Related Changes of the Collagen Crimp in the Human Cornea and Sclera

Collagen architecture in the third dimension:3D polarized light microscopy (3DPLM) for mapping in-plane (IP) and out-of-plane (OOP) collagen fiber architecture

Rapid learning curve assessment in an ex vivo training system for microincisional glaucoma surgery

Stretch-Induced Collagen Bundle Uncrimping and Recruitment are Independent of Depth in Equatorial Sclera

Between a basket and a finger trap: a unified model of posterior pole fiber architecture

Collagen Architecture of the Posterior Pole: High-Resolution Wide Field of View Visualization and Analysis Using Polarized Light Microscopy

Visualization and Quantification of Outflow after Ab Interno Trabeculectomy and Trabecular Micro-Bypass Stents using Differential Canalograms

Novel method reveals heterogeneous micro-scale response of sclera collagen bundles to homogeneous macro-scale stretch

Age-related changes in anterograde transport, axonal integrity and visuomotor function in DBA/2J and C57BL/6J mice

Identifying the Palisades of Vogt in Human Ex-vivo Tissue

A Central Role for Sympathetic Nerves in Herpes Stromal Keratitis in Mice

Ex-vivo remodeling of palisades of Vogt in preserved tissue

Collagen Crimp Period in the Corneoscleral Shell

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