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ARVO Annual Meeting Abstract June 2023

Piezo1 channels highly expressed in human RPE

Qin Wan; Joys Annika David; Congxiao Zhang; Tea Soon Park; Mitra Farnoodian; Eric Nguyen; Jair Montford; Colby Lewallen; Aman George; Kiyoharu Miyagishima; David McGaughey; Davide Ortolan; Devika Abhijit Bose; Arvydas Maminishkis; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2982.

ARVO Annual Meeting Abstract June 2023

VLC-PUFA supplementation increases Elovanoid synthesis in a two-compartment Late-Onset Retinal Degeneration-iRPE model

Jeff Xiang Ji; Jorgelina Muriel Calandria; Megan Cothern; Rasangi Perera; Kapil Bharti; Kiyoharu Miyagishima; Ruchi Sharma; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5456.

ARVO Annual Meeting Abstract June 2021

Cytoprotective Effects of Brimonidine in an Induced Pluripotent Stem Cell (iPSC)-Derived Retinal Pigment Epithelium (RPE) Model of Age-Related Macular Degeneration (AMD)

Lori-Ann Christie; Ruchi Sharma; Malika Nimmagadda; Davide Ortolan; Genqing Liang; Kiyoharu Joshua Miyagishima; Mitalee Tamhane; Mike Ly; William Change; Richard Graham; Shaoxin Feng; Francisco J Lopez; Brenda Smith; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):195.

ARVO Annual Meeting Abstract June 2021

Interaction between CTRP5 & AdipoR1 and its implication to Late-onset retinal degeneration (L-ORD)

Andrew Fausey; Congxiao Zhang; Malika Nimmagadda; Kiyoharu Joshua Miyagishima; Ruchi Sharma; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3062.

ARVO Annual Meeting Abstract June 2020

Hypoxia-induced Alterations of miR-204 Regulates Autophagy Activity in Human Retinal Pigment Epithelium (hRPE)

Congxiao Zhang; Kiyoharu J Miyagishima; Ruchi Sharma; Malika Nimmagadda; Genqing Liang; Arvydas Maminishkis; Kapil Bharti; Sheldon S Miller

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3110.

ARVO Annual Meeting Abstract July 2019

Elevation of miR-155 induces a non-canonical inflammasome activation pathway in human retinal pigment epithelium (hRPE)

Congxiao Zhang; Arvydas Maminishkis; Kiyoharu miyagishima; Genqing Liang; Fnu Ruchi; Sheldon S Miller

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):766.

ARVO Annual Meeting Abstract July 2019

Altered electrical responses in iPSC-RPE derived from distinct genetic eye diseases

Qin Wan; Mitra Farnoodian; Nathan Hotaling; Aman George; Kiyoharu miyagishima; Roba Dejene; Tyler Pfister; Arvydas Maminishkis; Brian Patrick Brooks; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6396.

ARVO Annual Meeting Abstract July 2018

Elovanoid profiling of iPSC-RPE derived from a family affected by Late-Onset Retinal Degeneration reveals attenuated neuroprotective signaling in patients

Bokkyoo Jun; Kiyoharu Joshua Miyagishima; Ruchi Sharma; Catherine A Cukras; Paul Sieving; Sheldon S Miller; Kapil Bharti; Nicolas G Bazan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3051.

ARVO Annual Meeting Abstract June 2017

CEP290 or IFT88 Loss of Function in RPE Suggest a Role for Primary Cilia in Human iPSC-RPE Maturation and Provide Insights into the Mechanism of Ciliopathy-Induced Retinal Degeneration

Qin Wan; Ruchi Sharma; Justin Chang; Vladimir Khristov; Kiyoharu Miyagishima; Roba Dejene; Quanlong Lu; Christopher Westlake; Meral Gunay-Aygun; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1056.

ARVO Annual Meeting Abstract June 2017

RPE miR-204 or -211 KNOCK OUT ALTERS CELL MORPHOLOGY AND FUNCTION

Congxiao Zhang; Helen Zhao; Nathan Hotaling; Kiyoharu Miyagishima; Raymond Zhou; Lijing Dong; Arvydas Maminishkis; Kapil Bharti; Sheldon S Miller

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3568.

ARVO Annual Meeting Abstract June 2017

Visual function following Nitisinone treatment in a mouse model of OCA-1B (Tyr c-h/c-h )

Ighovie Felix Onojafe; Friedrich Kretschmer; Jung-Woong Kim; Kiyoharu Miyagishima; Congxiao Zhang; Haohua Qian; Tudor C Badea; Brian Patrick Brooks

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5868.

ARVO Annual Meeting Abstract June 2017

Analysis of Secretory Lipidomics and Proteomics of Late-Onset Retinal Degeneration iPSC-derived RPE

Kiyoharu J Miyagishima; Ruchi Sharma; Katharina Clore-Gronenborn; Zoya Qureshy; Bokkyoo Jun; William C Gordon; Nathan Hotaling; Congxiao Zhang; Catherine A Cukras; Paul A Sieving; Nicolas Guillermo Bazan; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3019.

ARVO Annual Meeting Abstract September 2016

Primary Cilia Regulates Human iPSC-RPE Maturation via Regulation of WNT Signaling

Qin Wan; Balendu Jha; Helen May-Simera; Ruchi Sharma; Juliet Hartford; Vladimir Khristov; Kiyoharu Miyagishima; Mostafa Reza Lotfi; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):252.

ARVO Annual Meeting Abstract September 2016

Investigating the molecular mechanisms of Late-Onset Retinal Degeneration using patient-specific induced pluripotent stem cells

Zoya Qureshy; Kiyoharu Miyagishima; Katharina Clore-Gronenborn; Congxiao Zhang; Ruchi Sharma; Vaishakh Rajan; Vladimir Khristov; Catherine Cukras; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

Voltage-gated conductances increase the sensitivity of mouse rod photoresponses following pigment bleaching

Rikard Frederiksen; Johan Pahlberg; Gabriel Pollock; Kiyoharu Miyagishima; Soile Nymark; Alapakkam P Sampath; M Carter Cornwall

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract June 2015

Visual function and Nitisinone treatment in a mouse model of OCA1b (Tyr- c-h/c-h )

Ighovie Felix Onojafe; Haohua Qian; Kiyoharu Miyagishima; Congxiao Zhang; Sheldon S Miller; Brian Patrick Brooks; NEI

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1487.

ARVO Annual Meeting Abstract June 2015

Developing iPS Cell Derived RPE Tissue for Clinical Application

Vladimir Khristov; Juliet Hartford; Qin Wan; Mostafa Reza Lotfi; Kiyoharu Miyagishima; Nathan Hotaling; Arvydas Maminishkis; Juan Amaral; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1834.

ARVO Annual Meeting Abstract June 2015

Modeling Late-Onset Retinal Degeneration with Human iPSCs: Insights into the Shared Pathogenesis of Macular Degenerations

Katharina Clore-Gronenborn; Kiyoharu Miyagishima; Congxiao Zhang; Vaisakh Rajan; Jason Silver; Qin Wan; Ruchi Sharma; Catherine A Cukras; Sheldon S Miller; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2379.

ARVO Annual Meeting Abstract April 2014

Optimizing Biodegradable Scaffolds for Developing iPS Cell Derived RPE Tissue

Vladimir Khristov; Juliet Hartford; Qin Wan; Mostafa Reza Lotfi; Kiyoharu j Miyagishima; Arvydas Maminishkis; Juan Amaral; Sheldon S Miller; Janine Davis; Kapil Bharti

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1175.

ARVO Annual Meeting Abstract April 2014

Engineering iPS Cell Derived RPE Tissue Using Biodegradable Scaffolds

Kapil Bharti; Janine Davis; Juliet Hartford; Vladimir Khristov; Qin Wan; Mostafa Reza Lotfi; Kiyoharu j Miyagishima; Arvydas Maminishkis; Juan Amaral; Sheldon S Miller

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5245.

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Piezo1 channels highly expressed in human RPE

VLC-PUFA supplementation increases Elovanoid synthesis in a two-compartment Late-Onset Retinal Degeneration-iRPE model

Cytoprotective Effects of Brimonidine in an Induced Pluripotent Stem Cell (iPSC)-Derived Retinal Pigment Epithelium (RPE) Model of Age-Related Macular Degeneration (AMD)

Interaction between CTRP5 & AdipoR1 and its implication to Late-onset retinal degeneration (L-ORD)

Hypoxia-induced Alterations of miR-204 Regulates Autophagy Activity in Human Retinal Pigment Epithelium (hRPE)

Elevation of miR-155 induces a non-canonical inflammasome activation pathway in human retinal pigment epithelium (hRPE)

Altered electrical responses in iPSC-RPE derived from distinct genetic eye diseases

Elovanoid profiling of iPSC-RPE derived from a family affected by Late-Onset Retinal Degeneration reveals attenuated neuroprotective signaling in patients

CEP290 or IFT88 Loss of Function in RPE Suggest a Role for Primary Cilia in Human iPSC-RPE Maturation and Provide Insights into the Mechanism of Ciliopathy-Induced Retinal Degeneration

RPE miR-204 or -211 KNOCK OUT ALTERS CELL MORPHOLOGY AND FUNCTION

Visual function following Nitisinone treatment in a mouse model of OCA-1B (Tyr c-h/c-h )

Analysis of Secretory Lipidomics and Proteomics of Late-Onset Retinal Degeneration iPSC-derived RPE

Primary Cilia Regulates Human iPSC-RPE Maturation via Regulation of WNT Signaling

Investigating the molecular mechanisms of Late-Onset Retinal Degeneration using patient-specific induced pluripotent stem cells

Voltage-gated conductances increase the sensitivity of mouse rod photoresponses following pigment bleaching

Visual function and Nitisinone treatment in a mouse model of OCA1b (Tyr- c-h/c-h )

Developing iPS Cell Derived RPE Tissue for Clinical Application

Modeling Late-Onset Retinal Degeneration with Human iPSCs: Insights into the Shared Pathogenesis of Macular Degenerations

Optimizing Biodegradable Scaffolds for Developing iPS Cell Derived RPE Tissue

Engineering iPS Cell Derived RPE Tissue Using Biodegradable Scaffolds

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