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Retina April 2019

Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy

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Haitao Liu; Jie Tang; Yunpeng Du; Aicha Saadane; Ivy Samuels; Alex Veenstra; Jianying Z. Kiser; Krzysztof Palczewski; Timothy S. Kern
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, photoreceptors, phototransduction, rod photoreceptors, vision, mice, retina, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1538-1546. doi: 10.1167/iovs.18-26433

Physiology and Pharmacology April 2019

A Mixture of U.S. Food and Drug Administration–Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness

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Henri Leinonen; Elliot H. Choi; Anthony Gardella; Vladimir J. Kefalov; Krzysztof Palczewski
TAGS: retinal cone, disease susceptibility, night blindness, rod photoreceptors, transducin, united states food and drug administration, diagnostic imaging, eye, mice, retina, disease models
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1442-1453. doi: 10.1167/iovs.19-26560

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Protective effect of unbleachable retinal chromophore analogue against light-induced retinal degeneration in mice

Beata Jastrzebska; Songqi Gao; Grazyna Palczewska; Marcin Golczak; Zhigian Dong; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):369. doi:

ARVO Annual Meeting Abstract July 2018

Prevention of photoreceptor degeneration with FDA-accepted compounds

Henri O Leinonen; Tivadar Orban; Zhiqian Dong; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1591. doi:

ARVO Annual Meeting Abstract July 2018

Inner Retina Signaling and Well-Preserved Vision during Photoreceptor Degeneration in the P23H Retinitis Pigmentosa Model

Frans Vinberg; Henri O Leinonen; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1869. doi:

ARVO Annual Meeting Abstract July 2018

Profiling the regulatory networks controlling early steps of phagocytosis in the retinal pigmented epithelium

Aleksander Tworak; Cheng-Kang Chiang; Brian M Kevany; Bo Xu; Janice Mayne; Zhibin Ning; Daniel Figeys; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3983. doi:

ARVO Annual Meeting Abstract July 2018

Two-photon visual sensitivity of human cones - a psychophysical study

Katarzyna Paulina Komar; Daniel Ruminski; Agnieszka Zielinska; Karolina Kiluk; Grazyna Palczewska; Krzysztof Palczewski; Maciej Wojtkowski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4049. doi:

ARVO Annual Meeting Abstract July 2018

Role of Short-Term Light Adaptation Enabling Clearance of Retinaldehydes in Modulating Retinal Susceptibility to Light-Induced Injury

Malgorzata Barbara Rozanowska; Marcin Golczak; Akiko Maeda; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4978. doi:

ARVO Annual Meeting Abstract July 2018

Delivery and deployment of a ciliary actin dynamics module by PCARE drives the neogenesis of phototransductive membrane disks

Rob W J Collin; Julio Cesar Corral Serrano; Jeroen van Reeuwijk; Anita DM Hoogendoorn; Renate AA Ruigrok; Adem Yildirim; Stef JF Letteboer; Lonneke Duijkers; Sanae Sakami; Krzysztof Palczewski; Karsten Boldt; Uwe Wolfrum; Marius Ueffing; Alex Garanto; Ronald Roepman

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4979. doi:

Review September 2017

Towards Treatment of Stargardt Disease: Workshop Organized and Sponsored by the Foundation Fighting Blindness

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Avery E. Sears; Paul S. Bernstein; Artur V. Cideciyan; Carel Hoyng; Peter Charbel Issa; Krzysztof Palczewski; Philip J. Rosenfeld; SriniVas Sadda; Ulrich Schraermeyer; Janet R. Sparrow; Ilyas Washington; Hendrik P.N. Scholl
TAGS: blindness, stargardt's disease
Trans. Vis. Sci. Tech.. 2017; 6(5):6. doi: 10.1167/tvst.6.5.6

ARVO Annual Meeting Abstract June 2017

Identification of a novel small molecule chaperon of rhodopsin and its therapeutic potential in retinal degeneration

Yuanyuan Chen; Yu Chen; Beata Jastrzebska; Hong Tang; Xiaoyu Li; William Siebel; Jianye Zhang; Hui Jin; Sahil Gulati; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):253. doi:

ARVO Annual Meeting Abstract June 2017

Features of retinitis pigmentosa defined by high throughput sequencing and wide field imaging

Debarshi Mustafi; Krzysztof Palczewski; Hossein Ameri

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):279. doi:

ARVO Annual Meeting Abstract June 2017

Rational tuning of visual cycle modulator pharmacodynamics

Philip Kiser; Jianye Zhang; Mohsen Badiee; Gregory Tochtrop; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2970. doi:

ARVO Annual Meeting Abstract June 2017

Dephosphorylation of visual pigments by PP2A is required for timely dark adaptation of rods and cones

Alexander V Kolesnikov; Tivadar Orban; Krzysztof Palczewski; Vladimir J Kefalov

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3575. doi:

ARVO Annual Meeting Abstract June 2017

Apo-opsin forms a photoactivated rhodopsin-like state

Shinya Sato; Beata Jastrzebska; Andreas Engel; Krzysztof Palczewski; Vladimir J Kefalov

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5602. doi:

Multidisciplinary Ophthalmic Imaging January 2017

Formation and Clearance of All- Trans -Retinol in Rods Investigated in the Living Primate Eye With Two-Photon Ophthalmoscopy

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Robin Sharma; Christina Schwarz; Jennifer J. Hunter; Grazyna Palczewska; Krzysztof Palczewski; David R. Williams
TAGS: drug clearance, fluorescence, ophthalmoscopy, photons, primates, rhodopsin, rod photoreceptors, diagnostic imaging, eye, kinetics, vitamin a, bleach, excitation
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):604-613. doi: 10.1167/iovs.16-20061

ARVO Annual Meeting Abstract September 2016

Genetic signatures of rod and cone-dominant retinas and mouse models of retina degeneration

Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Comparative genomic analysis reveals a functional evolution of vision across mammals

Debarshi Mustafi; Brian Kevany; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6563. doi:

ARVO Annual Meeting Abstract September 2016

Can in vivo two-photon retinal imaging be safely applied in humans?

Christina Schwarz; Robin Sharma; William S Fischer; Mina M Chung; Grazyna Palczewska; Krzysztof Palczewski; David R Williams; Jennifer J Hunter

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1716. doi:

ARVO Annual Meeting Abstract September 2016

Characterization of two-photon vision by measurements of sensitivity threshold

Katarzyna Komar; Grazyna Palczewska; Jianye Zhang; Maciej Nowakowski; Zhiqian Dong; Krzysztof Palczewski; Maciej Wojtkowski

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):196. doi:

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Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy

A Mixture of U.S. Food and Drug Administration–Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness

Protective effect of unbleachable retinal chromophore analogue against light-induced retinal degeneration in mice

Prevention of photoreceptor degeneration with FDA-accepted compounds

Inner Retina Signaling and Well-Preserved Vision during Photoreceptor Degeneration in the P23H Retinitis Pigmentosa Model

Profiling the regulatory networks controlling early steps of phagocytosis in the retinal pigmented epithelium

Two-photon visual sensitivity of human cones - a psychophysical study

Role of Short-Term Light Adaptation Enabling Clearance of Retinaldehydes in Modulating Retinal Susceptibility to Light-Induced Injury

Delivery and deployment of a ciliary actin dynamics module by PCARE drives the neogenesis of phototransductive membrane disks

Towards Treatment of Stargardt Disease: Workshop Organized and Sponsored by the Foundation Fighting Blindness

Identification of a novel small molecule chaperon of rhodopsin and its therapeutic potential in retinal degeneration

Features of retinitis pigmentosa defined by high throughput sequencing and wide field imaging

Rational tuning of visual cycle modulator pharmacodynamics

Dephosphorylation of visual pigments by PP2A is required for timely dark adaptation of rods and cones

Apo-opsin forms a photoactivated rhodopsin-like state

Formation and Clearance of All- Trans -Retinol in Rods Investigated in the Living Primate Eye With Two-Photon Ophthalmoscopy

Genetic signatures of rod and cone-dominant retinas and mouse models of retina degeneration

Comparative genomic analysis reveals a functional evolution of vision across mammals

Can in vivo two-photon retinal imaging be safely applied in humans?

Characterization of two-photon vision by measurements of sensitivity threshold

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