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Articles July 2020

Clinical Application of Infrared-Light Microperimetry in the Assessment of Scotopic-Eye Sensitivity

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Grzegorz Łabuz; Asu Rayamajhi; Julia Usinger; Katarzyna Komar; Patrick Merz; Ramin Khoramnia; Grazyna Palczewska; Krzysztof Palczewski; Gerd U. Auffarth
TAGS: eye, infrared rays
Trans. Vis. Sci. Tech.. 2020; 9(8):7. doi: https://doi.org/10.1167/tvst.9.8.7

ARVO Annual Meeting Abstract June 2020

Light-driven regeneration of 11- cis -retinal in the retinal pigment epithelium

Elliot H Choi; Jianye Zhang; Aleksander Tworak; David Salom; Grazyna Palczewska; Philip David Kiser; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1519. doi:

ARVO Annual Meeting Abstract June 2020

Maintained scotopic contrast sensitivity is associated with increased rod to rod-bipolar cell signal transmission in retinitis pigmentosa

Nguyen Cao Pham; Henri Leinonen; Taylor Boyd; Johanes Santoso; Krzysztof Palczewski; Frans Vinberg

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4513. doi:

ARVO Annual Meeting Abstract June 2020

An Image-Based High Throughput Screening Assay for Compounds Mitigating the Effect of All- Trans- Retinal Toxicity in Photoreceptor Degeneration

Susie Suh; Tamar Getter; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4941. doi:

ARVO Annual Meeting Abstract July 2019

Small molecules selectively reduce the misfolded rhodopsin that causes retinitis pigmentosa

Yuanyuan Chen; Krzysztof Palczewski; Xujie Liu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):43. doi:

ARVO Annual Meeting Abstract July 2019

The phagocytic function of Müller glia in a mouse model of retinitis pigmentosa

Sanae Sakami; Yoshikazu Imanishi; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):444. doi:

ARVO Annual Meeting Abstract July 2019

New large animal model for RDH5 -associated retinopathies

Simon M Petersen-Jones; Laurence Occelli; Paige Winkler; Andrea Minella; Kelian Sun; Leslie Lyons; Anahita Daruwalla; Philip Kiser; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):458. doi:

ARVO Annual Meeting Abstract July 2019

Modulation of mouse rod signaling by llama-derived transducin nanobody

Guhan Iyer; Sahil Gulati; Krzysztof Palczewski; Vladimir Kefalov

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):568. doi:

ARVO Annual Meeting Abstract July 2019

Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones

Philip Kiser; Alexander V Kolesnikov; Jianying Kiser; Zhiqian Dong; Bhagirath Chaurasia; Liping Wang; Scott Summers; Thanh Hoang; Seth Blackshaw; Neal S Peachey; Vladimir Kefalov; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2369. doi:

ARVO Annual Meeting Abstract July 2019

Novel AAV Capsids Demonstrate Strong Retinal Expression in Non-Human Primates After Intravitreal Administration

Brian Kevany; Susie Suh; Jennings Lu; Linas Padegimas; Krzysztof Palczewski; Timothy Miller

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2900. doi:

ARVO Annual Meeting Abstract July 2019

Efficient Non-viral Gene Therapy for Stargardt’s Disease with pH-Sensitive Multifunctional Lipid ECO Plasmid DNA Nanoparticles

Da Sun; Rebecca Schur; Avery Sears; Songqi Gao; Rui Xin; Akiko Maeda; Krzysztof Palczewski; Zheng-Rong Lu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2915. doi:

Retina April 2019

Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy

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Haitao Liu; Jie Tang; Yunpeng Du; Aicha Saadane; Ivy Samuels; Alex Veenstra; Jianying Z. Kiser; Krzysztof Palczewski; Timothy S. Kern
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, mice, phototransduction, photoreceptors, retina, vision, rod photoreceptors, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1538-1546. doi: https://doi.org/10.1167/iovs.18-26433

Physiology and Pharmacology April 2019

A Mixture of U.S. Food and Drug Administration–Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness

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Henri Leinonen; Elliot H. Choi; Anthony Gardella; Vladimir J. Kefalov; Krzysztof Palczewski
TAGS: disease models, mice, night blindness, retina, retinal cone, united states food and drug administration, disease susceptibility, diagnostic imaging, eye, transducin
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1442-1453. doi: https://doi.org/10.1167/iovs.19-26560

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Protective effect of unbleachable retinal chromophore analogue against light-induced retinal degeneration in mice

Beata Jastrzebska; Songqi Gao; Grazyna Palczewska; Marcin Golczak; Zhigian Dong; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):369. doi:

ARVO Annual Meeting Abstract July 2018

Prevention of photoreceptor degeneration with FDA-accepted compounds

Henri O Leinonen; Tivadar Orban; Zhiqian Dong; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1591. doi:

ARVO Annual Meeting Abstract July 2018

Inner Retina Signaling and Well-Preserved Vision during Photoreceptor Degeneration in the P23H Retinitis Pigmentosa Model

Frans Vinberg; Henri O Leinonen; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1869. doi:

ARVO Annual Meeting Abstract July 2018

Profiling the regulatory networks controlling early steps of phagocytosis in the retinal pigmented epithelium

Aleksander Tworak; Cheng-Kang Chiang; Brian M Kevany; Bo Xu; Janice Mayne; Zhibin Ning; Daniel Figeys; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3983. doi:

ARVO Annual Meeting Abstract July 2018

Two-photon visual sensitivity of human cones - a psychophysical study

Katarzyna Paulina Komar; Daniel Ruminski; Agnieszka Zielinska; Karolina Kiluk; Grazyna Palczewska; Krzysztof Palczewski; Maciej Wojtkowski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4049. doi:

ARVO Annual Meeting Abstract July 2018

Role of Short-Term Light Adaptation Enabling Clearance of Retinaldehydes in Modulating Retinal Susceptibility to Light-Induced Injury

Malgorzata Barbara Rozanowska; Marcin Golczak; Akiko Maeda; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4978. doi:

ARVO Annual Meeting Abstract July 2018

Delivery and deployment of a ciliary actin dynamics module by PCARE drives the neogenesis of phototransductive membrane disks

Rob W J Collin; Julio Cesar Corral Serrano; Jeroen van Reeuwijk; Anita DM Hoogendoorn; Renate AA Ruigrok; Adem Yildirim; Stef JF Letteboer; Lonneke Duijkers; Sanae Sakami; Krzysztof Palczewski; Karsten Boldt; Uwe Wolfrum; Marius Ueffing; Alex Garanto; Ronald Roepman

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4979. doi:

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Clinical Application of Infrared-Light Microperimetry in the Assessment of Scotopic-Eye Sensitivity

Light-driven regeneration of 11- cis -retinal in the retinal pigment epithelium

Maintained scotopic contrast sensitivity is associated with increased rod to rod-bipolar cell signal transmission in retinitis pigmentosa

An Image-Based High Throughput Screening Assay for Compounds Mitigating the Effect of All- Trans- Retinal Toxicity in Photoreceptor Degeneration

Small molecules selectively reduce the misfolded rhodopsin that causes retinitis pigmentosa

The phagocytic function of Müller glia in a mouse model of retinitis pigmentosa

New large animal model for RDH5 -associated retinopathies

Modulation of mouse rod signaling by llama-derived transducin nanobody

Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones

Novel AAV Capsids Demonstrate Strong Retinal Expression in Non-Human Primates After Intravitreal Administration

Efficient Non-viral Gene Therapy for Stargardt’s Disease with pH-Sensitive Multifunctional Lipid ECO Plasmid DNA Nanoparticles

Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy

A Mixture of U.S. Food and Drug Administration–Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness

Protective effect of unbleachable retinal chromophore analogue against light-induced retinal degeneration in mice

Prevention of photoreceptor degeneration with FDA-accepted compounds

Inner Retina Signaling and Well-Preserved Vision during Photoreceptor Degeneration in the P23H Retinitis Pigmentosa Model

Profiling the regulatory networks controlling early steps of phagocytosis in the retinal pigmented epithelium

Two-photon visual sensitivity of human cones - a psychophysical study

Role of Short-Term Light Adaptation Enabling Clearance of Retinaldehydes in Modulating Retinal Susceptibility to Light-Induced Injury

Delivery and deployment of a ciliary actin dynamics module by PCARE drives the neogenesis of phototransductive membrane disks

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