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Clinical Trials August 2022

Lateral Geniculate Nucleus Volume Determined on MRI Correlates With Corresponding Ganglion Cell Layer Loss in Acquired Human Postgeniculate Lesions

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Cyril Fabian Simmen; Fabienne Catherine Fierz; Lars Michels; Njoud Aldusary; Klara Landau; Marco Piccirelli; Ghislaine Lieselotte Traber
TAGS: ganglia, lateral geniculate body, magnetic resonance imaging, volume
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):18. doi: https://doi.org/10.1167/iovs.63.9.18

Clinical and Epidemiologic Research August 2022

Macular Layer Thickness and Effect of BMI, Body Fat, and Traditional Cardiovascular Risk Factors: The Tromsø Study

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Therese von Hanno; Live Lund Hareide; Lars Småbrekke; Bente Morseth; Monica Sneve; Maja Gran Erke; Ellisiv Bøgeberg Mathiesen; Geir Bertelsen
TAGS: body fat, body mass index procedure, heart disease risk factors, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):16. doi: https://doi.org/10.1167/iovs.63.9.16

Includes: Supplemental Content

Glaucoma August 2022

Prediagnostic Plasma Metabolomics and the Risk of Exfoliation Glaucoma

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Jae H. Kang; Oana Zeleznik; Lisa Frueh; Jessica Lasky-Su; A. Heather Eliassen; Clary Clish; Bernard A. Rosner; Louis R. Pasquale; Janey L. Wiggs
TAGS: exfoliation syndrome, metabolites, plasma, metabolomics
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):15. doi: https://doi.org/10.1167/iovs.63.9.15

Includes: Supplemental Content

Retina August 2022

Retinal Microvasculature and Choriocapillaris Flow Deficit in Relation to Serum Uric Acid Using Swept-Source Optical Coherence Tomography Angiography

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Yu Lu; Jing Yue; Jian Chen; Xue Li; Lanhua Wang; Wenyong Huang; Jianyu Zhang; Ting Li
TAGS: angiogram, fluid flow, hyperuricemia, microcirculation, optical coherence tomography, retinal vasculature, urate measurement, serum, uric acid
Trans. Vis. Sci. Tech.. 2022; 11(8):9. doi: https://doi.org/10.1167/tvst.11.8.9

Includes: Supplemental Content

Retina August 2022

Correlation of Diabetic Disease Severity to Degree of Quadrant Asymmetry in En Face OCTA Metrics

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Jesse J. Jung; Shen Yi Lim; Xavier Chan; Srinivas R. Sadda; Quan V. Hoang
TAGS: diabetes mellitus, diabetic retinopathy, eye, face, nonproliferative diabetic retinopathy, severity of illness, diagnostic imaging, parafoveal region
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):12. doi: https://doi.org/10.1167/iovs.63.9.12

Genetics August 2022

An Insertion Variant in CRH Confers an Increased Risk of Central Serous Chorioretinopathy

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En-Zhong Jin; Tian-Qi Li; Chi Ren; Li Zhu; Wei Du; Jin-Feng Qu; Yu-Ou Yao; Xiao-Xin Li; Peng Zhou; Lv-Zhen Huang; Ming-Wei Zhao
TAGS: central serous chorioretinopathy
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):9. doi: https://doi.org/10.1167/iovs.63.9.9

Includes: Supplemental Content

Artificial Intelligence August 2022

AOSLO-net: A Deep Learning-Based Method for Automatic Segmentation of Retinal Microaneurysms From Adaptive Optics Scanning Laser Ophthalmoscopy Images

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Qian Zhang; Konstantina Sampani; Mengjia Xu; Shengze Cai; Yixiang Deng; He Li; Jennifer K. Sun; George Em Karniadakis
TAGS: learning, macrophage activation syndrome, meconium aspiration syndrome, optics, retinal microaneurysm, scanning laser ophthalmoscopy, datasets, masks, training, perfusion
Trans. Vis. Sci. Tech.. 2022; 11(8):7. doi: https://doi.org/10.1167/tvst.11.8.7

Includes: Supplemental Content

Cornea & External Disease August 2022

Changes in Rat Scleral Collagen Structure Induced by UVA–Riboflavin Crosslinking at Various Tissue Depths in Whole Globe Versus Scleral Patch

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Yuan Miao; Juan Liu; Sruti S. Akella; Jessie Wang; Shaowei Li; Roy S. Chuck; Cheng Zhang
TAGS: body tissue, collagen, corneal collagen cross-linking, eye, riboflavin, sclera, ultraviolet a radiation, collagen fiber
Trans. Vis. Sci. Tech.. 2022; 11(8):2. doi: https://doi.org/10.1167/tvst.11.8.2

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology August 2022

Interocular Transfer: The Dichoptic Flash-Lag Effect in Controls and Amblyopes

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Xi Wang; Yutong Song; Meng Liao; Robert F. Hess; Longqian Liu; Alexandre Reynaud
TAGS: amblyopia, retinal correspondence
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):2. doi: https://doi.org/10.1167/iovs.63.9.2

Retina August 2022

Reduction of Laser-Induced Choroidal Neovascularization in Mice With Erythropoietin RNA Interference

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Wenjuan Lv; Wen Chen; Shaofen Huang; Yanxuan Xu; Jia-Jian Liang; Yuqian Zheng; Shaowan Chen; Shao-Lang Chen; Tsz Kin Ng; Haoyu Chen
TAGS: choroidal neovascularization, erythropoietin, lasers, mice, choroid, rna interference, rna, small interfering, proteins
Trans. Vis. Sci. Tech.. 2022; 11(8):1. doi: https://doi.org/10.1167/tvst.11.8.1

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging July 2022

Photoreceptor and Retinal Pigment Epithelium Relationships in Eyes With Vitelliform Macular Dystrophy Revealed by Multimodal Adaptive Optics Imaging

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Tao Liu; Nancy Aguilera; Andrew J. Bower; Joanne Li; Ehsan Ullah; Alfredo Dubra; Catherine Cukras; Brian P. Brooks; Brett G. Jeffrey; Robert B. Hufnagel; Laryssa A. Huryn; Wadih M. Zein; Johnny Tam
TAGS: diagnostic imaging, eye, retinal cone, vitelliform dystrophy, optics, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):27. doi: https://doi.org/10.1167/iovs.63.8.27

Includes: Supplemental Content

Article July 2022

Characteristic fixation biases in Super-Recognizers

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Marcel Linka; Maximilian Davide Broda; Tamara Alsheimer; Benjamin de Haas; Meike Ramon
TAGS: face, russell-silver syndrome, somatostatin receptor scintigraphy, eye
Journal of Vision. 2022; 22(8):17. doi: https://doi.org/10.1167/jov.22.8.17

Retina July 2022

LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia

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Chenyang Zhao; Yusen Liu; Jiayu Meng; Xiaotang Wang; Xianyang Liu; Wanqian Li; Qian Zhou; Junjie Xiang; Na Li; Shengping Hou
TAGS: 1-phosphatidylinositol 3-kinase, akt signaling pathway, angiogenesis, hypoxia, microglia
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):25. doi: https://doi.org/10.1167/iovs.63.8.25

Ocular Oncology July 2022

The Use of Panitumumab-IRDye800CW in a Novel Murine Model for Conjunctival Squamous Cell Carcinoma

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Gun Min Youn; Ayden G. Case; Trent Jarin; BaoXiang Li; Aditi Swarup; Andrea Naranjo; Charbel Bou-Khalil; Jacqueline Yao; Quan Zhou; Marisa E. Hom; Eben L. Rosenthal; Albert Y. Wu
TAGS: conjunctiva, diagnostic imaging, mice, panitumumab, squamous cell carcinoma, injections, tumor growth
Trans. Vis. Sci. Tech.. 2022; 11(7):23. doi: https://doi.org/10.1167/tvst.11.7.23

Retina July 2022

EGF Receptor Signaling Modulates YAP Activation and Promotes Experimental Proliferative Vitreoretinopathy

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Wei Zhang; Jing Li
TAGS: epidermal growth factor receptors, signal transduction, vitreoretinopathy, proliferative
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):24. doi: https://doi.org/10.1167/iovs.63.8.24

Immunology and Microbiology July 2022

Apolipoprotein A1 Modulates Teff/Treg Balance Through Scavenger Receptor Class B Type I-Dependent Mechanisms in Experimental Autoimmune Uveitis

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Haixiang Huang; Zhuang Li; Jun Huang; Yanyan Xie; Zhiqiang Xiao; Yunwei Hu; Guanyu Chen; Minzhen Wang; Zuoyi Li; Qian Chen; Wenjie Zhu; Wenru Su; Yan Luo; Xiaoqing Chen; Dan Liang
TAGS: apolipoprotein a-i, autoimmunity, balance, device, equilibrium, immune response, mice, receptors, scavenger, regulatory t-lymphocytes, t-lymphocytes, uveitis
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):23. doi: https://doi.org/10.1167/iovs.63.8.23

Includes: Supplemental Content

Artificial Intelligence July 2022

A Multicenter Clinical Study of the Automated Fundus Screening Algorithm

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Fei Li; Jianying Pan; Dalu Yang; Junde Wu; Yiling Ou; Huiting Li; Jiamin Huang; Huirui Xie; Dongmei Ou; Xiaoyi Wu; Binghong Wu; Qinpei Sun; Huihui Fang; Yehui Yang; Yanwu Xu; Yan Luo; Xiulan Zhang
TAGS: screening, software, glasgow coma scale
Trans. Vis. Sci. Tech.. 2022; 11(7):22. doi: https://doi.org/10.1167/tvst.11.7.22

Glaucoma July 2022

Cohort Study of Race/Ethnicity and Incident Primary Open-Angle Glaucoma Characterized by Autonomously Determined Visual Field Loss Patterns

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Jae H. Kang; Mengyu Wang; Lisa Frueh; Bernard Rosner; Janey L. Wiggs; Tobias Elze; Louis R. Pasquale
TAGS: ethnic group, eye, glaucoma, open-angle glaucoma, cohort studies, blindness, visual field defects
Trans. Vis. Sci. Tech.. 2022; 11(7):21. doi: https://doi.org/10.1167/tvst.11.7.21

Includes: Supplemental Content

Artificial Intelligence July 2022

Automated Detection of Vascular Leakage in Fluorescein Angiography – A Proof of Concept

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LeAnne H. Young; Jongwoo Kim; Mehmet Yakin; Henry Lin; David T. Dao; Shilpa Kodati; Sumit Sharma; Aaron Y. Lee; Cecilia S. Lee; H. Nida Sen
TAGS: fluorescein angiography, proof of concept studies, training, uveitis, clinicians, deep learning
Trans. Vis. Sci. Tech.. 2022; 11(7):19. doi: https://doi.org/10.1167/tvst.11.7.19

Includes: Supplemental Content

Cornea & External Disease July 2022

Ocular Surface Immune Cell Profiles in Contact Lens–Induced Discomfort

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Archana Padmanabhan Nair; Swaminathan Sethu; Harsha Nagaraj; Vijay Kumar; Sriharsha Nagaraj; Zohra Fadli; Charles Scales; Mike Chemaly; Xiao-Yu Song; Arkasubhra Ghosh; Bailin Liang
TAGS: contact lenses, lens (device), lens, crystalline, ocular surfaces, cytology
Trans. Vis. Sci. Tech.. 2022; 11(7):16. doi: https://doi.org/10.1167/tvst.11.7.16

Includes: Supplemental Content

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Lateral Geniculate Nucleus Volume Determined on MRI Correlates With Corresponding Ganglion Cell Layer Loss in Acquired Human Postgeniculate Lesions

Macular Layer Thickness and Effect of BMI, Body Fat, and Traditional Cardiovascular Risk Factors: The Tromsø Study

Prediagnostic Plasma Metabolomics and the Risk of Exfoliation Glaucoma

Retinal Microvasculature and Choriocapillaris Flow Deficit in Relation to Serum Uric Acid Using Swept-Source Optical Coherence Tomography Angiography

Correlation of Diabetic Disease Severity to Degree of Quadrant Asymmetry in En Face OCTA Metrics

An Insertion Variant in CRH Confers an Increased Risk of Central Serous Chorioretinopathy

AOSLO-net: A Deep Learning-Based Method for Automatic Segmentation of Retinal Microaneurysms From Adaptive Optics Scanning Laser Ophthalmoscopy Images

Changes in Rat Scleral Collagen Structure Induced by UVA–Riboflavin Crosslinking at Various Tissue Depths in Whole Globe Versus Scleral Patch

Interocular Transfer: The Dichoptic Flash-Lag Effect in Controls and Amblyopes

Reduction of Laser-Induced Choroidal Neovascularization in Mice With Erythropoietin RNA Interference

Photoreceptor and Retinal Pigment Epithelium Relationships in Eyes With Vitelliform Macular Dystrophy Revealed by Multimodal Adaptive Optics Imaging

Characteristic fixation biases in Super-Recognizers

LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia

The Use of Panitumumab-IRDye800CW in a Novel Murine Model for Conjunctival Squamous Cell Carcinoma

EGF Receptor Signaling Modulates YAP Activation and Promotes Experimental Proliferative Vitreoretinopathy

Apolipoprotein A1 Modulates Teff/Treg Balance Through Scavenger Receptor Class B Type I-Dependent Mechanisms in Experimental Autoimmune Uveitis

A Multicenter Clinical Study of the Automated Fundus Screening Algorithm

Cohort Study of Race/Ethnicity and Incident Primary Open-Angle Glaucoma Characterized by Autonomously Determined Visual Field Loss Patterns

Automated Detection of Vascular Leakage in Fluorescein Angiography – A Proof of Concept

Ocular Surface Immune Cell Profiles in Contact Lens–Induced Discomfort

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