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Retina July 2019

Arginine and Carnitine Metabolites Are Altered in Diabetic Retinopathy

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Katherine Sumarriva; Karan Uppal; Chunyu Ma; David J. Herren; Yating Wang; Isaac M. Chocron; Cassandra Warden; Sabrina L. Mitchell; L. Goodwin Burgess; Megan P. Goodale; Melissa P. Osborn; Allison J. Ferreira; Janice C. Law; Edward F. Cherney; Dean P. Jones; Milam A. Brantley, Jr
TAGS: arginine, carnitine, diabetic retinopathy, metabolites, nonproliferative diabetic retinopathy, diabetes mellitus
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3119-3126. doi: https://doi.org/10.1167/iovs.19-27321

Includes: Supplemental Content

Retina October 2018

The Carnitine Shuttle Pathway is Altered in Patients With Neovascular Age-Related Macular Degeneration

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Sabrina L. Mitchell; Karan Uppal; Samantha M. Williamson; Ken Liu; L. Goodwin Burgess; ViLinh Tran; Allison C. Umfress; Kelli L. Jarrell; Jessica N. Cooke Bailey; Anita Agarwal; Margaret Pericak-Vance; Jonathan L. Haines; William K. Scott; Dean P. Jones; Milam A. Brantley, Jr
TAGS: carnitine, exudative age-related macular degeneration, metabolites, metabolomics, plasma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4978-4985. doi: https://doi.org/10.1167/iovs.18-25137

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

CXCR4 expression in an intraocular melanoma mouse model with hepatic metastases

Hua Yang; Shanshan Tan; Hans E Grossniklaus; Vanessa Marie Morales; Qing Zhang; Barry L Burgess; Dan-Ning Hu; Scott E Woodman; Tara A McCannel; Jenny Yang

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1254. doi:

ARVO Annual Meeting Abstract September 2016

Non-targeted plasma metabolomics of diabetic retinopathy demonstrates increased arginine and related metabolites

Milam A Brantley; David J. Herren; Karan Uppal; L. Goodwin Burgess; Isaac Chocron; M. Wade Calcutt; David C. Samuels; Dean P. Jones

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Glaucoma July 2015

Metabolome-Wide Association Study of Primary Open Angle Glaucoma

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L. Goodwin Burgess; Karan Uppal; Douglas I. Walker; Rachel M. Roberson; ViLinh Tran; Megan B. Parks; Emily A. Wade; Alexandra T. May; Allison C. Umfress; Kelli L. Jarrell; Brooklyn O. C. Stanley; John Kuchtey; Rachel W. Kuchtey; Dean P. Jones; Milam A. Brantley, Jr
TAGS: metabolomics, open-angle glaucoma, metabolites
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):5020-5028. doi: https://doi.org/10.1167/iovs.15-16702

Includes: Supplemental Content

Genetics September 2014

Mitochondrial Haplogroups Are Associated With Severity of Diabetic Retinopathy

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Christopher B. Estopinal; Isaac M. Chocron; Megan B. Parks; Emily A. Wade; Rachel M. Roberson; L. Goodwin Burgess; Milam A. Brantley, Jr; David C. Samuels
TAGS: cohort studies, diabetes mellitus, type 2, diabetic retinopathy, mitochondria, diabetes mellitus
Invest. Ophthalmol. Vis. Sci.. 2014; 55(9):5589-5595. doi: https://doi.org/10.1167/iovs.14-15149

Includes: Supplemental Content

Glaucoma August 2014

Elevated Transforming Growth Factor β1 in Plasma of Primary Open-Angle Glaucoma Patients

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John Kuchtey; Jessica Kunkel; L. Goodwin Burgess; Megan B. Parks; Milam A. Brantley, Jr; Rachel W. Kuchtey
TAGS: open-angle glaucoma, plasma, transforming growth factor alpha, transforming growth factors, thrombospondin 1
Invest. Ophthalmol. Vis. Sci.. 2014; 55(8):5291-5297. doi: https://doi.org/10.1167/iovs.14-14578

ARVO Annual Meeting Abstract April 2014

Metabolic pathways altered in neovascular age-related macular degeneration

Milam A Brantley; Karan Uppal; Samantha L Williamson; L. Goodwin Burgess; Anita Agarwal; Margaret A Pericak-Vance; Jonathan Haines; Dean P Jones

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1650. doi:

ARVO Annual Meeting Abstract April 2014

Mitochondrial genetic effects on proliferative diabetic retinopathy

Christopher Estopinal; Isaac M Chocron; Megan B Parks; Emily A Wade; L. Goodwin Burgess; David C Samuels; Milam A Brantley

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2236. doi:

ARVO Annual Meeting Abstract April 2014

Metabolic divergence among patients with primary open angle glaucoma

L. Goodwin Burgess; Karan Uppal; Rachel M. Roberson; ViLinh Tran; John Kuchtey; Rachel W Kuchtey; Dean P Jones; Milam A Brantley

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4521. doi:

ARVO Annual Meeting Abstract April 2014

Metabolic profiles associated with primary open-angle glaucoma

Rachel M. Roberson; Karan Uppal; L. Goodwin Burgess; ViLinh Tran; John Kuchtey; Rachel W Kuchtey; Dean P Jones; Milam A Brantley

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5703. doi:

ARVO Annual Meeting Abstract June 2013

Elevated TGFβ1 concentration in the plasma of glaucoma patients

John Kuchtey; L. Goodwin Burgess; Megan Parks; Jessica Kunkel; Milam Brantley; Rachel Kuchtey

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1597. doi:

ARVO Annual Meeting Abstract June 2013

Metabolites that discriminate between neovascular AMD and control patients associate with different ARMS2 genotypes

Megan Parks; Youngja Park; L. Goodwin Burgess; Kichun Lee; Paul Sternberg; Dean Jones; Milam Brantley

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4115. doi:

ARVO Annual Meeting Abstract June 2013

Metabolic pathways associated with Age-related Macular Degeneration (AMD)

L. Goodwin Burgess; Youngja Park; Megan Parks; Kichun Lee; Paul Sternberg; Dean Jones; Milam Brantley

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4117. doi:

ARVO Annual Meeting Abstract June 2013

Subclassification of clinically-indistinguishable AMD patients based on metabolic characteristics

Milam Brantley; Youngja Park; Megan Parks; L. Goodwin Burgess; Karan Uppal; Paul Sternberg; Dean Jones

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3664. doi:

ARVO Annual Meeting Abstract March 2012

Cytogenetic Heterogeneity Within Fine Needle Biopsies Of Uveal Melanomas Possessing Both Monosomy 3 And Chromosome 6p Gain

Vinod B. Voleti; Nagesh P. Rao; Barry L. Burgess; Tara A. McCannel

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3337. doi:

Clinical Trials May 2011

Genomic Identification of Significant Targets in Ciliochoroidal Melanoma

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Tara A. McCannel; Barry L. Burgess; Stanley F. Nelson; Ascia Eskin; Bradley R. Straatsma
TAGS: genome, melanoma, genes, cancer
Invest. Ophthalmol. Vis. Sci.. 2011; 52(6):3018-3022. doi: https://doi.org/10.1167/iovs.10-5864

ARVO Annual Meeting Abstract April 2011

Modeling Mitogen-activated Protein Kinase Pathway Activity In Novel Uveal Melanoma Cell Lines

Barry L. Burgess; Antoni Ribas; Erika Von Euw; Tara A. McCannel

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1442. doi:

ARVO Annual Meeting Abstract April 2010

Genomic Identification of Significant Targets in Cancer (GISTIC) Analysis Resolves Regional Chromosomal Aberrations in 6q, 8p, 13q and16q of Primary Ciliochoroidal Melanomas Examined by GeneChip 250k Mapping Arrays

B. L. Burgess; S. F. Nelson; A. Eskin; B. R. Straatsma; T. A. McCannel

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):855. doi:

ARVO Annual Meeting Abstract April 2009

Sequential Probing for Subtelomeric Arms of Chromosome 6 and Centromeric Chromosome 3 in Choroidal Melanoma Fine Needle Aspiration Biopsies

T. A. McCannel; B. L. Burgess; N. P. Rao; B. R. Straatsma

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):3373. doi:

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Arginine and Carnitine Metabolites Are Altered in Diabetic Retinopathy

The Carnitine Shuttle Pathway is Altered in Patients With Neovascular Age-Related Macular Degeneration

CXCR4 expression in an intraocular melanoma mouse model with hepatic metastases

Non-targeted plasma metabolomics of diabetic retinopathy demonstrates increased arginine and related metabolites

Metabolome-Wide Association Study of Primary Open Angle Glaucoma

Mitochondrial Haplogroups Are Associated With Severity of Diabetic Retinopathy

Elevated Transforming Growth Factor β1 in Plasma of Primary Open-Angle Glaucoma Patients

Metabolic pathways altered in neovascular age-related macular degeneration

Mitochondrial genetic effects on proliferative diabetic retinopathy

Metabolic divergence among patients with primary open angle glaucoma

Metabolic profiles associated with primary open-angle glaucoma

Elevated TGFβ1 concentration in the plasma of glaucoma patients

Metabolites that discriminate between neovascular AMD and control patients associate with different ARMS2 genotypes

Metabolic pathways associated with Age-related Macular Degeneration (AMD)

Subclassification of clinically-indistinguishable AMD patients based on metabolic characteristics

Cytogenetic Heterogeneity Within Fine Needle Biopsies Of Uveal Melanomas Possessing Both Monosomy 3 And Chromosome 6p Gain

Genomic Identification of Significant Targets in Ciliochoroidal Melanoma

Modeling Mitogen-activated Protein Kinase Pathway Activity In Novel Uveal Melanoma Cell Lines

Genomic Identification of Significant Targets in Cancer (GISTIC) Analysis Resolves Regional Chromosomal Aberrations in 6q, 8p, 13q and16q of Primary Ciliochoroidal Melanomas Examined by GeneChip 250k Mapping Arrays

Sequential Probing for Subtelomeric Arms of Chromosome 6 and Centromeric Chromosome 3 in Choroidal Melanoma Fine Needle Aspiration Biopsies

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