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Retina July 2025

Exosomal miRNA Profiling in Liquid Biopsy of Vitreous in Proliferative Diabetic Retinopathy

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Bin Yan; Jianing Qiu; Yan Yang; Jing Luo; Dan Liu; Lusi Zhang; Zhishang Meng; Huiling Li; Xiaojian Guo; Jun Zeng; Chun Ding; Manyun Xie; Kejun Long
TAGS: micrornas, vitreous body, proliferative diabetic retinopathy, liquid biopsy, exosomes
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):24. https://doi.org/10.1167/iovs.66.9.24

Glaucoma July 2025

Decoding the Cornea-Glaucoma Association: Evidence From Mendelian Randomization

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Victor A. de Vries; Anita Szabo; Joëlle E. Vergroesen; Siyin Liu; Karin A. van Garderen; Kirithika Muthusamy; Petra Liskova; Lubica Dudakova; Anthony P. Khawaja; Stephen J. Tuft; Caroline C. W. Klaver; Alice E. Davidson; Wishal D. Ramdas
TAGS: cardiac ct, cohort studies, cornea, glaucoma, mendelian randomization analysis, genetic risk score, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):22. https://doi.org/10.1167/iovs.66.9.22

Includes: Supplemental Content

Glaucoma July 2025

Gaze-Induced Optic Nerve Head Deformations Are Greater in High Myopia and Strains Increase With Axial Length

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Tingting Liu; Ya Xing Wang; Jost B. Jonas; Quan V. Hoang; Michaël J. A. Girard; Xiaofei Wang
TAGS: eye, gaze, myopia, optic disk, eye movement, sclera, adduction
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):21. https://doi.org/10.1167/iovs.66.9.21

Includes: Supplemental Content

Retina July 2025

Choroidal Features of Cynomolgus Macaques in Relation to Age and Axial Length

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Guitong Ye; Yuan Zhang; Shaofen Huang; Jinan Zhan; Ruiyu Luo; Rui Xie; Yuyao Ling; Ye Deng; Caibin Deng; Wei Liu; Zhiwei Huang; Chusheng Zhang; Junshu Wu; Zhidong Li; Yehong Zhuo
TAGS: cardiovascular imaging, choroid, cortical blindness, macaca, macaca fascicularis, myopia, eye, antidepressive agents, tricyclic, trichloroacetic acid, adult
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):17. https://doi.org/10.1167/iovs.66.9.17

Includes: Supplemental Content

Immunology and Microbiology July 2025

The Gut Microbial System Responds to Retinal Injury and Modulates the Outcomes by Regulating Innate Immune Activation

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Xuexue Cui; Caijiao Yi; Jian Liu; Jinyan Qi; Wen Deng; Xiangling Yuan; Ruiqi Zhou; Mei Chen; Qiang Xiang; Heping Xu
TAGS: antibiotics, gastrointestinal microbiome, mice, retinal injuries, wounds and injuries, laser injuries, attenuation, lasers
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):6. https://doi.org/10.1167/iovs.66.9.6

Includes: Supplemental Content

Visual Neuroscience July 2025

Evidence for M 2 Muscarinic Receptor Antagonist Delay of Myopia Development Through Activation of Kir3.4 Channel in the Retina of Guinea Pigs

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Hong Zhou; Guimei Zhou; Qin Yang; Jiahao Niu; Runzhe Wang; Huilan Liu; Suwen Hou; Hongsheng Bi; Xuan Liao
TAGS: antagonists, caviidae, muscarinic acetylcholine receptor, myopia, retina, mass or substance concentration per volume
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):5. https://doi.org/10.1167/iovs.66.9.5

ARVO Annual Meeting Abstract June 2025

Post-Pandemic Myopia in Children and Adolescents: Long-Term Impact, Parental Perspectives, and Practical Strategies for Myopia Intervention

yuhang liu; Xiaohang Chen; Lulu Li; Longqian Liu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5176.

ARVO Annual Meeting Abstract June 2025

Identification of disease-responsive neuronal promoters and enhancers for glaucoma gene therapy

Yuyang Zeng; Xue Feng; Wenjun Yan; Liang Liu; Haoliang Huang; Fuyun Bian; Yang Hu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2661.

ARVO Annual Meeting Abstract June 2025

A Functional Magnetic Resonance Imaging Study on the Functional Alterations in Facial Recognition Between Amblyopic Patients and Healthy Controls

Gantian Huang; Xiaohang Chen; Ping Jiang; Longqian Liu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3649.

ARVO Annual Meeting Abstract June 2025

One-year myopia control effect of Asymmetric Multi-point Positive Defocus (AMPD) spectacle lenses in Chinese children: A prospective randomized clinical trial

Longqian Liu; Siyu Bian; Xiaofang Hu; Bi Yang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5239.

ARVO Annual Meeting Abstract June 2025

NIPAAM-Based Thermo-Responsive Hydrogel with MMP-Controlled and Sustained Anti-VEGF Delivery to the Posterior Segment of the Eye

Fanqing Ma; Lina Liu; Heather Sheardown

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4343.

ARVO Annual Meeting Abstract June 2025

Development of Potent Bispecific Inhibitors Targeting Complement Pathways and Cytokines for the Treatment of Geographic Atrophy

Catherine Cho; Joyce Kwong; Yimeng Shen; Namrata Prasad; Jason Lin; Anatolii Purchel; Kiho Song; Lili Liu; Theodore Leng; Hong Liang; Dolly Chang; D. Victor Perlroth; Fernando Corrêa

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4337.

ARVO Annual Meeting Abstract June 2025

Delivery of Therapeutic Oligonucleotides by Antibody Biopolymer Conjugates

Lili Liu; Namrata Prasad; Anatolii Purchel; Jason Lin; Yimeng Shen; Kiho Song; Angie Korpusik; Jing Ren; Dolly Chang; Hong Liang; D. Victor Perlroth; Fernando Corrêa

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4334.

ARVO Annual Meeting Abstract June 2025

Effect of Polymer Architecture on Properties of Antibody Biopolymer Conjugates

Jason Lin; Anatolii Purchel; Namrata Prasad; Lili Liu; Kiho Song; Yimeng Shen; Didier Benoit; Dolly Chang; Hong Liang; D. Victor Perlroth; Fernando Corrêa

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4325.

ARVO Annual Meeting Abstract June 2025

PEG-coated nanoparticles to sustain drug release for ophthalmic drug delivery

Nhi Thi Yen Tran; Lina Liu; Heather Sheardown

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6102.

ARVO Annual Meeting Abstract June 2025

The relationship between accommodative lag and myopia progression in children wearing Individualized Ocular Refraction Customization spectacle lenses

Ji Kou; Ye Wu; Si Lei; Xiaohang Chen; Longqian Liu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2808.

ARVO Annual Meeting Abstract June 2025

HONU: Baseline Characteristics of the quantitative Contrast Sensitivity Function (qCSF) in Patients with Intermediate Age-related Macular Degeneration

Justin Elstrott; Chen Chen; Verena Steffen; Simon S. Gao; Miao Zhang; Katie M Litts; Michael C Chang; Jiameng Zhang; Luis A Lesmes; Michael Dorr; Hao Chen; Liang Liu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):684.

ARVO Annual Meeting Abstract June 2025

Pb exposure decreases the cell density of oligodendrocyte precursor cells and oligodendrocytes in the optic nerve.

Labony Khandokar; Luke Liu; Wei Zheng; Patrick Kerstein

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):207.

ARVO Annual Meeting Abstract June 2025

Niacinamide protect visual function in optic nerve stroke

Liping Liu; Shweta Modgil; Ali Shariati; Min Young Kim; Tazbir Ahmed; Hugo Wu; Yaping Joyce Liao

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4907.

ARVO Annual Meeting Abstract June 2025

Reciprocal regulation of local thyroid hormone signaling and ER stress in the sclera drives myopia progression

Pengbo Zhang; Nanji Lu; Yan Nie; Longqian Liu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4564.

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Exosomal miRNA Profiling in Liquid Biopsy of Vitreous in Proliferative Diabetic Retinopathy

Decoding the Cornea-Glaucoma Association: Evidence From Mendelian Randomization

Gaze-Induced Optic Nerve Head Deformations Are Greater in High Myopia and Strains Increase With Axial Length

Choroidal Features of Cynomolgus Macaques in Relation to Age and Axial Length

The Gut Microbial System Responds to Retinal Injury and Modulates the Outcomes by Regulating Innate Immune Activation

Evidence for M 2 Muscarinic Receptor Antagonist Delay of Myopia Development Through Activation of Kir3.4 Channel in the Retina of Guinea Pigs

Post-Pandemic Myopia in Children and Adolescents: Long-Term Impact, Parental Perspectives, and Practical Strategies for Myopia Intervention

Identification of disease-responsive neuronal promoters and enhancers for glaucoma gene therapy

A Functional Magnetic Resonance Imaging Study on the Functional Alterations in Facial Recognition Between Amblyopic Patients and Healthy Controls

One-year myopia control effect of Asymmetric Multi-point Positive Defocus (AMPD) spectacle lenses in Chinese children: A prospective randomized clinical trial

NIPAAM-Based Thermo-Responsive Hydrogel with MMP-Controlled and Sustained Anti-VEGF Delivery to the Posterior Segment of the Eye

Development of Potent Bispecific Inhibitors Targeting Complement Pathways and Cytokines for the Treatment of Geographic Atrophy

Delivery of Therapeutic Oligonucleotides by Antibody Biopolymer Conjugates

Effect of Polymer Architecture on Properties of Antibody Biopolymer Conjugates

PEG-coated nanoparticles to sustain drug release for ophthalmic drug delivery

The relationship between accommodative lag and myopia progression in children wearing Individualized Ocular Refraction Customization spectacle lenses

HONU: Baseline Characteristics of the quantitative Contrast Sensitivity Function (qCSF) in Patients with Intermediate Age-related Macular Degeneration

Pb exposure decreases the cell density of oligodendrocyte precursor cells and oligodendrocytes in the optic nerve.

Niacinamide protect visual function in optic nerve stroke

Reciprocal regulation of local thyroid hormone signaling and ER stress in the sclera drives myopia progression

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