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Immunology and Microbiology March 2025

Differential Roles of Macrophages and Microglia in Subretinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration

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Manon Szczepan; María Llorián-Salvador; Caijiao Yi; David Hughes; Matthias Mack; Mei Chen; Heping Xu
TAGS: fibrosis, lasers, macrophages, microglia, exudative age-related macular degeneration, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):41. https://doi.org/10.1167/iovs.66.3.41

Includes: Supplemental Content

Visual Neuroscience February 2025

OCT-Based Retina Assessment Reflects Visual Impairment in Multiple Sclerosis

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Natacha Stolowy; Lilija Gutmann; Margareta Lüpke; Thierry David; Michael Dorr; Christina Mayer; Christoph Heesen; Frederike Cosima Oertel; Ting-Yi Lin; Friedemann Paul; Hanna Gwendolyn Zimmermann; Jan-Patrick Stellmann
TAGS: multiple sclerosis, optic neuritis, retina, vision, visual impairment, eye, medical history
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):39. https://doi.org/10.1167/iovs.66.2.39

Includes: Supplemental Content

Genetics February 2025

Gene Variant Spectrum in Probands With Familial Exudative Vitreoretinopathy Using an Expanded Panel

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Sarah van der Ende; Karen Bedard; Karin Wallace; Michael P. Mackley; Mathew Nightingale; Daniel Gaston; M. Jill Beis; Marissa A. Leblanc; Roxanne Gillett; Alex V. Levin; Ian H. Clark; Élise Héon; Rajeev H. Muni; Elias I. Traboulsi; Christopher J. Lyons; Christopher R. McMaster; Johane M. Robitaille; on behalf of The FEVR Consortium
TAGS: familial exudative vitreoretinopathies, genes, proband
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):23. https://doi.org/10.1167/iovs.66.2.23

Includes: Supplemental Content

Cornea February 2025

Senolytic Treatment Alleviates Corneal Allograft Rejection Through Upregulation of Angiotensin-Converting Enzyme 2 (ACE2)

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Hao Chi; Li Ma; Fanxing Zeng; Xiaolei Wang; Peng Peng; Xiaofei Bai; Ting Zhang; Wenhui Yin; Yaoyao Yu; Lingling Yang; Qingjun Zhou; Chao Wei; Weiyun Shi
TAGS: aging, allografting, angiotensin converting enzyme 2, cornea, keratoplasty, navitoclax, rejection (psychology), senolytics, stress, transplant rejection
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):15. https://doi.org/10.1167/iovs.66.2.15

Includes: Supplemental Content

Cornea January 2025

Proteomics Reveals Mechanisms of Delayed Keratoconus Progression: A Study of Corneas Following Two Light-Activated Crosslinking Treatments

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Demi H. J. Vogels; Jurriaan Brekelmans; Ronny Mohren; Naomi R. N. Vos; Alexander Brandis; Arie L. Marcovich; Berta Cillero-Pastor; Avigdor Scherz; Vanessa L. S. LaPointe; Mor M. Dickman
TAGS: cornea, corneal collagen cross-linking, did not receive therapy or drug, keratoconus, lipids, proteomics, ultraviolet a radiation, proteins
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):64. https://doi.org/10.1167/iovs.66.1.64

Includes: Supplemental Content

Lens January 2025

Mechanical Properties of Eye Lens Cortical and Nuclear Membranes and the Whole Lens

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Nawal K. Khadka; Dieter Haemmerle; Paul H. Davis; Laxman Mainali
TAGS: lens (device), lens, crystalline, nuclear envelope, tissue membrane, cattle, lipids
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):27. https://doi.org/10.1167/iovs.66.1.27

Retina January 2025

A Penetrable AAV2 Capsid Variant for Efficient Intravitreal Gene Delivery to the Retina

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Xiaoyu He; Yidian Fu; Yangfan Xu; Liang Ma; Peiwei Chai; Hanhan Shi; Yizheng Yao; Shengfang Ge; Renbing Jia; Xuyang Wen; Zhi Yang; Xianqun Fan
TAGS: capsid, gene therapy, genes, intravitreal injections, mice, retina, injections, eye
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):6. https://doi.org/10.1167/iovs.66.1.6

Includes: Supplemental Content

Low Vision Rehabilitation January 2025

How People With Vision Impairment Use Their Gaze to Hit a Ball

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Ward Nieboer; Carin M. Svensen; Kjell van Paridon; Debbie Van Biesen; David L. Mann
TAGS: gaze, visual impairment, eye, peripheral vision
Trans. Vis. Sci. Tech.. 2025; 14(1):1. https://doi.org/10.1167/tvst.14.1.1

Retina December 2024

Retinal Degeneration Associated With Biallelic RDH12 Variants: Longitudinal Evaluation of Retinal Structure and Visual Function in Pediatric Patients

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Tomas S. Aleman; Alejandro J. Roman; Katherine E. Uyhazi; Yu You Jiang; Emma C. Bedoukian; Alexander Sumaroka; Vivian Wu; Malgorzata Swider; Iryna Viarbitskaya; Robert C. Russell; Elizabeth O. Shagena; Arlene J. Santos; Leona W. Serrano; Kelsey M. Parchinski; Rebecca J. Kim; Mariejel L. Weber; Alexandra V. Garafalo; Dorothy A. Thompson; Albert M. Maguire; Jean Bennett; Drew H. Scoles; Erin C. O'Neil; Jessica I. W. Morgan; Artur V. Cideciyan
TAGS: pediatrics, retina, retinal cone, retinal degeneration, vision, photoreceptors, diagnostic imaging, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):30. https://doi.org/10.1167/iovs.65.14.30

Includes: Supplemental Content

Retina December 2024

Choroidal and Choriocapillaris OCT-A Analysis in Patients Affected by Active Central Serous Chorioretinopathy

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Maria Ludovica Ruggeri; Marzia Passamonti; Alberto Quarta; Olgers Koci; Annamaria Porreca; Marta Di Nicola; Lucio Zeppa; Rodolfo Mastropasqua; Lisa Toto
TAGS: central serous chorioretinopathy
Trans. Vis. Sci. Tech.. 2024; 13(12):14. https://doi.org/10.1167/tvst.13.12.14

Cornea & External Disease December 2024

Quantifying the Corneal Nerve Whorl Pattern

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Maryse Lapierre-Landry; Eric Y. Lu; Matthew T. McPheeters; Made Airanthi K. Widjaja-Adhi; David L. Wilson; Rony R. Sayegh; Patricia R. Taylor; Marcin Golczak; Michael W. Jenkins
TAGS: cornea, datasets, neurons, mice, diabetes mellitus
Trans. Vis. Sci. Tech.. 2024; 13(12):11. https://doi.org/10.1167/tvst.13.12.11

Includes: Supplemental Content

Retina November 2024

Diabetes Renders Photoreceptors Susceptible to Retinal Ischemia-Reperfusion Injury

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David A. Antonetti; Cheng-Mao Lin; Sumathi Shanmugam; Heather Hager; Manjing Cao; Xuwen Liu; Alyssa Dreffs; Adam Habash; Steven F. Abcouwer
TAGS: diabetes mellitus, wounds and injuries, mice, retina, photoreceptors, reperfusion injury, streptozocin
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):46. https://doi.org/10.1167/iovs.65.13.46

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Potential Prognostic Protein Biomarkers in Tears From Noninfectious Uveitis Patients Under Biologic Treatment as a Prelude to Personalized Medicine

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Lorena Rodríguez-Martínez; Carmen Antía Rodríguez-Fernández; Olalla Rodríguez Lemos; Begoña de Domingo; Pere García Bru; Jesús Mateos; Anxo Fernández-Ferreiro
TAGS: biological markers, proteins, tumor necrosis factors, uveitis, individualized medicine, patient prognosis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):29. https://doi.org/10.1167/iovs.65.13.29

Includes: Supplemental Content

Retinal Cell Biology November 2024

Growth Hormone Neuroprotective Effects After an Optic Nerve Crush in the Male Rat

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David Epardo; Jerusa E. Balderas-Márquez; Cynthia A. Rodríguez-Arzate; Stéphanie C. Thébault; Martha Carranza; Maricela Luna; José Ávila-Mendoza; Denisse Calderón-Vallejo; J. Luis Quintanar; Carlos Arámburo; Carlos G. Martínez-Moreno
TAGS: axonal transport, electroretinography, neuroprotection, neuroprotective effect, optic nerve, proteins, retina, somatotropin, somatropin, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):17. https://doi.org/10.1167/iovs.65.13.17

Includes: Supplemental Content

Glaucoma October 2024

Diagnostic Performance for Detection of Glaucomatous Structural Damage Using Pixelwise Analysis of Retinal Thickness Measurements

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Hongli Yang; Juan Reynaud; Glen P. Sharpe; Dawn Jennings; Cindy Albert; Trinity Holthausen; Xiue Jiang; Shaban Demirel; Steven L. Mansberger; Marcelo T. Nicolela; Stuart K. Gardiner; Balwantray C. Chauhan; Claude F. Burgoyne; Brad Fortune
TAGS: eye, glaucoma, pixel
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):17. https://doi.org/10.1167/iovs.65.12.17

Includes: Supplemental Content

Article October 2024

The visual experience dataset: Over 200 recorded hours of integrated eye movement, odometry, and egocentric video

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Michelle R. Greene; Benjamin J. Balas; Mark D. Lescroart; Paul R. MacNeilage; Jennifer A. Hart; Kamran Binaee; Peter A. Hausamann; Ronald Mezile; Bharath Shankar; Christian B. Sinnott; Kaylie Capurro; Savannah Halow; Hunter Howe; Mariam Josyula; Annie Li; Abraham Mieses; Amina Mohamed; Ilya Nudnou; Ezra Parkhill; Peter Riley; Brett Schmidt; Matthew W. Shinkle; Wentao Si; Brian Szekely; Joaquin M. Torres; Eliana Weissmann
TAGS: calibration, datasets, eye movement, gaze, pupil, eye-tracking, eye
Journal of Vision. 2024; 24(11):6. https://doi.org/10.1167/jov.24.11.6

Article October 2024

The dichoptic contrast ordering test: A method for measuring the depth of binocular imbalance

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Alex S. Baldwin; Marie-Céline Lorenzini; Annabel Wing-Yan Fan; Robert F. Hess; Alexandre Reynaud
TAGS: imbalance, lens (device), eye, lens, crystalline, filters
Journal of Vision. 2024; 24(11):2. https://doi.org/10.1167/jov.24.11.2

Multidisciplinary Ophthalmic Imaging September 2024

Plexus-Specific Retinal Capillary Blood Flow Analysis Using Erythrocyte Mediated Angiography and Optical Coherence Tomography Angiography

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Victoria Y. Chen; Jessica A. Pottenburgh; Shih-En Chen; Sarah Kim; Lakyn Mayo; Aashka Damani; Marvin Cruz; Ashley Park; Lily Im; Laurence Magder; Osamah J. Saeedi
TAGS: angiogram, blood capillaries, erythrocytes, vascular flow, velocity, optical coherence tomography, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):33. https://doi.org/10.1167/iovs.65.11.33

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Does Leveraging the Human Ventral Visual Stream Improve Neural Network Robustness?

Zhenan Shao; Linjian Ma; Bo Li; Diane M. Beck

Journal of Vision. 2024; 24(10):277. https://doi.org/10.1167/jov.24.10.277

Vision Sciences Society Annual Meeting Abstract September 2024

Effective connectivity of the human cortical face network through concurrent intracerebral electrical stimulation and frequency-tagged visual presentation

Luna Angelini; Bruno Rossion; Corentin Jacques; Marie-Alphée Laurent; Louis Maillard; Sophie Colnat-Coulbois; Jacques Jonas

Journal of Vision. 2024; 24(10):506. https://doi.org/10.1167/jov.24.10.506

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Differential Roles of Macrophages and Microglia in Subretinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration

OCT-Based Retina Assessment Reflects Visual Impairment in Multiple Sclerosis

Gene Variant Spectrum in Probands With Familial Exudative Vitreoretinopathy Using an Expanded Panel

Senolytic Treatment Alleviates Corneal Allograft Rejection Through Upregulation of Angiotensin-Converting Enzyme 2 (ACE2)

Proteomics Reveals Mechanisms of Delayed Keratoconus Progression: A Study of Corneas Following Two Light-Activated Crosslinking Treatments

Mechanical Properties of Eye Lens Cortical and Nuclear Membranes and the Whole Lens

A Penetrable AAV2 Capsid Variant for Efficient Intravitreal Gene Delivery to the Retina

How People With Vision Impairment Use Their Gaze to Hit a Ball

Retinal Degeneration Associated With Biallelic RDH12 Variants: Longitudinal Evaluation of Retinal Structure and Visual Function in Pediatric Patients

Choroidal and Choriocapillaris OCT-A Analysis in Patients Affected by Active Central Serous Chorioretinopathy

Quantifying the Corneal Nerve Whorl Pattern

Diabetes Renders Photoreceptors Susceptible to Retinal Ischemia-Reperfusion Injury

Potential Prognostic Protein Biomarkers in Tears From Noninfectious Uveitis Patients Under Biologic Treatment as a Prelude to Personalized Medicine

Growth Hormone Neuroprotective Effects After an Optic Nerve Crush in the Male Rat

Diagnostic Performance for Detection of Glaucomatous Structural Damage Using Pixelwise Analysis of Retinal Thickness Measurements

The visual experience dataset: Over 200 recorded hours of integrated eye movement, odometry, and egocentric video

The dichoptic contrast ordering test: A method for measuring the depth of binocular imbalance

Plexus-Specific Retinal Capillary Blood Flow Analysis Using Erythrocyte Mediated Angiography and Optical Coherence Tomography Angiography

Does Leveraging the Human Ventral Visual Stream Improve Neural Network Robustness?

Effective connectivity of the human cortical face network through concurrent intracerebral electrical stimulation and frequency-tagged visual presentation

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