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ARVO Annual Meeting Abstract June 2021

Differences in gene expression and metabolism among AMD and non-AMD patients arise only after iPSC are differentiated into RPE

Huey Cai; Jie Gong; Lawrence J Rizzolo; Lucian V Del Priore; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):251. doi:

Retinal Cell Biology February 2021

Knockdown of Claudin-19 in the Retinal Pigment Epithelium Is Accompanied by Slowed Phagocytosis and Increased Expression of SQSTM1

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Fanfei Liu; Shaomin Peng; Ron A. Adelman; Lawrence J. Rizzolo
TAGS: phagocytosis, retinal pigment epithelium, proteins, ampk, rna, small interfering, catabolism, western blotting
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):14. doi: https://doi.org/10.1167/iovs.62.2.14

Includes: Supplemental Content

Retinal Cell Biology November 2020

Partially Differentiated Neuroretinal Cells Promote Maturation of the Retinal Pigment Epithelium

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Deepti Singh; Xiaoyu Chen; Tina Xia; Maryam Ghiassi-Nejad; Laurel Tainsh; Ron A. Adelman; Lawrence J. Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):9. doi: https://doi.org/10.1167/iovs.61.13.9

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Altered Gene Expression Profile in iPSC-derived RPE Cells from AMD Patients

Huey Cai; Jie Gong; Lawrence J Rizzolo; Lucian V Del Priore; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2276. doi:

ARVO Annual Meeting Abstract June 2020

Knock-down of claudin-19 induces an anti-oxidation response and slows phagocytosis in the retinal pigment epithelium

Fanfei Liu; Shaomin Peng; Ron A Adelman; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3113. doi:

ARVO Annual Meeting Abstract June 2020

The tight junction protein, claudin-19, does not require association with tight junctions to regulate gene expression in the retinal pigment epithelium

Lawrence J Rizzolo; Fanfei Liu; Tao Xu; Ron A Adelman; Shaomin Peng

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3115. doi:

ARVO Annual Meeting Abstract June 2020

Decreased phagocytosis of photoreceptor outer segments in patient-specific iPSC-derived RPE on diseased basement membrane

Jie Gong; Huey Cai; Lawrence J Rizzolo; Mark Anthony Fields; Lucian V Del Priore

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4153. doi:

ARVO Annual Meeting Abstract July 2019

Pleiotropic effects of claudin-19 on RPE gene expression include autophagy

Fanfei Liu; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1665. doi:

ARVO Annual Meeting Abstract July 2019

Laminin-521 promotes the formation of a planar retinal organoid

XIAOYU CHEN; Deepti Singh; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3315. doi:

ARVO Annual Meeting Abstract June 2017

Disease-causing mutations of CLDN19 alter gene expression in retinal pigment epithelia (RPE) and diminish visual function

Tao Xu; Shao-Bin Wang; Ron A Adelman; Shaomin Peng; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3591. doi:

ARVO Annual Meeting Abstract June 2017

Towards culturing retinal progenitor cells as a planar sheet

Tina Xia; Deepti Singh; Laurel Tainsh; Ron A Adelman; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4557. doi:

ARVO Annual Meeting Abstract June 2017

Retinal progenitor cells (RPC) cultured on planar scaffolds can integrate into the degenerated retina of rd10 mice and retain markers of differentiation

Deepti Singh; Shao-Bin Wang; Tina Xia; Laurel Tainsh; Maryam Ghiassi-Nejad; Ron A Adelman; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4566. doi:

ARVO Annual Meeting Abstract September 2016

Self organization of human induced pluripotent stem cell (iPSC) derived retinal progenitor cells on a 3D scaffold.

Laurel T Tainsh; Deepti Singh; SHAO-BIN WANG; Maryam Ghiassi-Nejad; Bo Chen; Ron A Adelman; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1147. doi:

ARVO Annual Meeting Abstract September 2016

Scaffold Composition Affects the Proliferation and Differentiation of Retinal Progenitor Cells

Maryam Ghiassi-Nejad; Deepti Singh; SHAO-BIN WANG; Laurel T Tainsh; Bo Chen; Ron A Adelman; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1149. doi:

ARVO Annual Meeting Abstract September 2016

Factors affecting protein aggregation for bevacizumab

Alexander T Nguyen; Laurel T Tainsh; Patrick Coady; Maryam Ghiassi; Lawrence J Rizzolo; Ron A Adelman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4003. doi:

ARVO Annual Meeting Abstract September 2016

Exogenous claudin-3 and claudin-19 rescue ARPE19 from dedifferentiation

SHAO-BIN WANG; Shaomin Peng; Deepti Singh; Ron A Adelman; Bo Chen; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6028. doi:

Retinal Cell Biology November 2015

Human Adult Retinal Pigment Epithelial Stem Cell–Derived RPE Monolayers Exhibit Key Physiological Characteristics of Native Tissue

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Timothy A. Blenkinsop; Janmeet S. Saini; Arvydas Maminishkis; Kapil Bharti; Qin Wan; Tina Banzon; Mostafa Lotfi; Janine Davis; Deepti Singh; Lawrence J. Rizzolo; Sheldon Miller; Sally Temple; Jeffrey H. Stern
TAGS: adult, body tissue, epithelial stem cells, physiology, pigment, gene expression, proteins, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2015; 56(12):7085-7099. doi: https://doi.org/10.1167/iovs.14-16246

Includes: Supplemental Content

Retinal Cell Biology March 2015

TRP Channels Localize to Subdomains of the Apical Plasma Membrane in Human Fetal Retinal Pigment Epithelium

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Peter Y. Zhao; Geliang Gan; Shaomin Peng; Shao-Bin Wang; Bo Chen; Ron A. Adelman; Lawrence J. Rizzolo
TAGS: barium, cell membrane, fetus, proteins, retinal pigment epithelium, tight junctions, calcium, tissue membrane, fluorescent antibody technique, immunoblotting
Invest. Ophthalmol. Vis. Sci.. 2015; 56(3):1916-1923. doi: https://doi.org/10.1167/iovs.14-15738

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Role of claudin-19 and claudin-3 on the barrier function of human retinal pigment epithelium (RPE)

Shaomin Peng; Peter Yu Cheng Zhao; Ron A Adelman; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2964. doi:

ARVO Annual Meeting Abstract April 2014

Autophagy over the lifespan: using fetal, stem cell, and adult RPE cultures to model the pathogenesis of AMD

Katherine Jean Davis; Shabnam Pakneshan; Peter Yu Cheng Zhao; Haben Kefella; Ron A Adelman; Lawrence J Rizzolo

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):371. doi:

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Differences in gene expression and metabolism among AMD and non-AMD patients arise only after iPSC are differentiated into RPE

Knockdown of Claudin-19 in the Retinal Pigment Epithelium Is Accompanied by Slowed Phagocytosis and Increased Expression of SQSTM1

Partially Differentiated Neuroretinal Cells Promote Maturation of the Retinal Pigment Epithelium

Altered Gene Expression Profile in iPSC-derived RPE Cells from AMD Patients

Knock-down of claudin-19 induces an anti-oxidation response and slows phagocytosis in the retinal pigment epithelium

The tight junction protein, claudin-19, does not require association with tight junctions to regulate gene expression in the retinal pigment epithelium

Decreased phagocytosis of photoreceptor outer segments in patient-specific iPSC-derived RPE on diseased basement membrane

Pleiotropic effects of claudin-19 on RPE gene expression include autophagy

Laminin-521 promotes the formation of a planar retinal organoid

Disease-causing mutations of CLDN19 alter gene expression in retinal pigment epithelia (RPE) and diminish visual function

Towards culturing retinal progenitor cells as a planar sheet

Retinal progenitor cells (RPC) cultured on planar scaffolds can integrate into the degenerated retina of rd10 mice and retain markers of differentiation

Self organization of human induced pluripotent stem cell (iPSC) derived retinal progenitor cells on a 3D scaffold.

Scaffold Composition Affects the Proliferation and Differentiation of Retinal Progenitor Cells

Factors affecting protein aggregation for bevacizumab

Exogenous claudin-3 and claudin-19 rescue ARPE19 from dedifferentiation

Human Adult Retinal Pigment Epithelial Stem Cell–Derived RPE Monolayers Exhibit Key Physiological Characteristics of Native Tissue

TRP Channels Localize to Subdomains of the Apical Plasma Membrane in Human Fetal Retinal Pigment Epithelium

Role of claudin-19 and claudin-3 on the barrier function of human retinal pigment epithelium (RPE)

Autophagy over the lifespan: using fetal, stem cell, and adult RPE cultures to model the pathogenesis of AMD

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