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ARVO Annual Meeting Abstract July 2018

Intravitreal Brimonidine Drug Delivery System (Brimo DDS Generation 1) Enhances Spatial Sweep Visual Evoked Potential (sVEP) in a Non-human Primate Model of Chronic Glaucoma

James A Burke; Kai-Ming Zhang; Werhner Orilla; Corine Ghosn; Larry A Wheeler

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1246. doi:

ARVO Annual Meeting Abstract June 2015

Focal Light-emitting-diode (LED)-induced cone photoreceptor degeneration in mice can be prevented with Brimonidine or trophic factors.

Manuel Vidal-Sanz; F Javier Valiente-Soriano; Arturo Ortin-Martinez; Diego García-Ayuso; Manuel Jiménez-López; Jose M Bernal-Garro; Luis Alarcón-Martínez; Larry A Wheeler; Maria Paz Villegas-Perez

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5667. doi:

ARVO Annual Meeting Abstract April 2014

Regulatory T cell mediated suppression of dendritic cells in a mouse model of dry eye

Katherine S Held; Chris S Schaumburg; Jianping Gao; Julio Nieves; Euikyon Oh; Larry A Wheeler; Virginia L Calder; Jerry Y Niederkorn; Stephen C Pflugfelder; Michael E Stern

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3653. doi:

ARVO Annual Meeting Abstract April 2014

Impact of the Host Microbiota on the Development of Murine Desiccating Stress-Induced Dry Eye Disease

Chris S Schaumburg; Katherine S Held; Annie M Ratanapinta; Madhuri Paul; Larry A Wheeler; Margarita Calonge; Jerry Y Niederkorn; Stephen C Pflugfelder; Michael E Stern

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3657. doi:

ARVO Annual Meeting Abstract April 2014

Role of CD147 in Experimental Autoimmune Anterior Uveitis (EAAU)

Jianping Gao; Reuben Sana; Larry A Wheeler; Virginia L Calder; Stephen C Pflugfelder; Margarita Calonge; Jerry Y Niederkorn; Michael E Stern

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1876. doi:

ARVO Annual Meeting Abstract April 2014

Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury

Won-Kyu Ju; Sang Yeop Kim; Myoung Sup Sim; Keun-Young Kim; Robert N Weinreb; Larry A Wheeler

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2431. doi:

ARVO Annual Meeting Abstract April 2014

Stress-Induced Damage to the Ocular Surface Resembling Dry Eye can Occur Independently of Chronic T cell-mediated Disease

Michael E Stern; Katherine S Held; Chris S Schaumburg; Euikyon Oh; Sveti Ugarte; Larry A Wheeler; Margarita Calonge; Jerry Y Niederkorn; Stephen C Pflugfelder

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3059. doi:

Cornea July 2013

Mitochondrial Permeability Transition Pore in Inflammatory Apoptosis of Human Conjunctival Epithelial Cells and T Cells: Effect of Cyclosporin A

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Jianping Gao; Reuben Sana; Virginia Calder; Margarita Calonge; Wanju Lee; Larry A. Wheeler; Michael E. Stern
TAGS: apoptosis, inflammation, mitochondria, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, permeability, t-lymphocyte, conjunctiva, cyclosporine, conjunctival epithelial cells
Invest. Ophthalmol. Vis. Sci.. 2013; 54(7):4717-4733. doi: 10.1167/iovs.13-11681

ARVO Annual Meeting Abstract June 2013

Plasmacytoid Dendritic Cells are the Primary Source of IFN-α During the Immunopathogenesis of Desiccating Stress-Induced Dry Eye Disease

Michael Stern; Chris Schaumburg; Jianping Gao; Annie Ratanapinta; Virginia Calder; Larry Wheeler; Jerry Niederkorn; Stephen Pflugfelder; Bruce Beutler; Argyrios Theofilopoulos

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4323. doi:

ARVO Annual Meeting Abstract June 2013

Potential Regulatory T Cell Mechanisms Of Immune Suppression In A Mouse Model Of Dry Eye

Katherine Held; Chris Schaumburg; Jianping Gao; Larry Wheeler; Margarita Calonge; Jerry Niederkorn; Stephen Pflugfelder; Michael Stern

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):919. doi:

ARVO Annual Meeting Abstract June 2013

Molecular Mechanisms of Inflammatory Apoptosis of Conjunctival Epithelial Cells and T cells: Effect of Cyclosporin A (CsA)

Jianping Gao; Reuben Sana; Virginia Calder; Margarita Calonge; Wanju Lee; Larry Wheeler; Michael Stern

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2122. doi:

ARVO Annual Meeting Abstract June 2013

Mice with Desiccating Stress-Induced Dry Eye Develop Trigeminal Neuralgia, Despite Decreased Corneal Sensitivity and Nerve Fiber Degeneration

Chris Schaumburg; Katherine Held; Euikyun Oh; Sveti Ugarte; Larry Wheeler; Margarita Calonge; Jerry Niederkorn; Stephen Pflugfelder; Robert Fox; Michael Stern

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2194. doi:

Retinal Cell Biology November 2012

Protective Effect of Carnosic Acid, a Pro-Electrophilic Compound, in Models of Oxidative Stress and Light-Induced Retinal Degeneration

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Tayebeh Rezaie; Scott R. McKercher; Kunio Kosaka; Masaaki Seki; Larry Wheeler; Veena Viswanath; Teresa Chun; Rabina Joshi; Marcos Valencia; Shunsuke Sasaki; Terumasa Tozawa; Takumi Satoh; Stuart A. Lipton
TAGS: antioxidants, oxidative stress, cell lines, electroretinography, genes, photoreceptors, retinal degeneration, enzymes, proteins, rats, retina
Invest. Ophthalmol. Vis. Sci.. 2012; 53(12):7847-7854. doi: 10.1167/iovs.12-10793

Includes: Supplemental Content

Cornea April 2012

Autoantibodies Contribute to the Immunopathogenesis of Experimental Dry Eye Disease

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Michael E. Stern; Chris S. Schaumburg; Karyn F. Siemasko; Jianping Gao; Larry A. Wheeler; Devin A. Grupe; Cintia S. De Paiva; Virginia L. Calder; Margarita Calonge; Jerry Y. Niederkorn; Stephen C. Pflugfelder
TAGS: autoantibodies, dry eye syndromes, immunoglobulin g, mice
Invest. Ophthalmol. Vis. Sci.. 2012; 53(4):2062-2075. doi: 10.1167/iovs.11-9299

ARVO Annual Meeting Abstract March 2012

Plasmacytoid Dendritic Cells are Modulated During the Immunopathogenesis of Desiccating Stress-Induced Experimental Dry Eye

Michael E. Stern; Christopher S. Schaumburg; Jianping Gao; Anh V. Duong; Annie M. Ratanapinta; Virginia L. Calder; Larry A. Wheeler; Jerry Y. Niederkorn; Stephen C. Pflugfelder; Argyrios N. Theofilopoulos

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2327. doi:

ARVO Annual Meeting Abstract March 2012

Cyclosporin A (CsA) Induces T Cell Apoptosis and Protects Human Conjunctival Epithelial Cells (IOBA-NHC) from Stress-Induced Apoptosis via Modulation of the Mitochondria Permeability Transition Pore (MPTP)

Jianping Gao; Reuben Sana; Margarita Calonge; Larry A. Wheeler; Michael E. Stern

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3978. doi:

ARVO Annual Meeting Abstract March 2012

Alterations in Corneal Nerve Fiber Density and Pain Markers during the Progression of Desiccating Stress-Induced Dry Eye Disease

Chris S. Schaumburg; Euikyun Oh; Sveti Patel; Jianping Gao; Larry A. Wheeler; Margarita Calonge; Jerry Y. Niederkorn; Stephen C. Pflugfelder; Robert I. Fox; Michael E. Stern

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1796. doi:

Physiology and Pharmacology May 2011

Treatment of Experimental Anterior and Intermediate Uveitis by a Dexamethasone Intravitreal Implant

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Corine R. Ghosn; Yong Li; Werhner C. Orilla; Ton Lin; Larry Wheeler; James A. Burke; Michael R. Robinson; Scott M. Whitcup
TAGS: inflammatory markers, inflammation, dexamethasone, anterior chamber of eye, oryctolagus cuniculus, uveitis, uveitis, intermediate, vitreous body, ciliary body, eye, iris, immune reconstitution inflammatory syndrome, histopathology tests, implants, intravitreal implants
Invest. Ophthalmol. Vis. Sci.. 2011; 52(6):2917-2923. doi: 10.1167/iovs.10-5939

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2011

The Role Of Ocular Pigmentation In The Intraocular Pressure Response To Brimonidine In Rabbits

James A. Burke; Lupe Ruiz; Barbara Feldmann; Werhner Orilla; Corine Ghosn; Louis Lo; Jinsong NI; Jie Shen; Larry Wheeler

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2466. doi:

ARVO Annual Meeting Abstract April 2011

Experimental CNV in Cynomolgus Monkeys after Sustained Release of VEGF and bFGF within the Suprachoroidal Space: Part 2. Natural History

Corinne G. Wong; Ton Lin; Yong Li; James Burke; Timothy You; Larry Wheeler; Corine Ghosn

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4000. doi:

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Intravitreal Brimonidine Drug Delivery System (Brimo DDS Generation 1) Enhances Spatial Sweep Visual Evoked Potential (sVEP) in a Non-human Primate Model of Chronic Glaucoma

Focal Light-emitting-diode (LED)-induced cone photoreceptor degeneration in mice can be prevented with Brimonidine or trophic factors.

Regulatory T cell mediated suppression of dendritic cells in a mouse model of dry eye

Impact of the Host Microbiota on the Development of Murine Desiccating Stress-Induced Dry Eye Disease

Role of CD147 in Experimental Autoimmune Anterior Uveitis (EAAU)

Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury

Stress-Induced Damage to the Ocular Surface Resembling Dry Eye can Occur Independently of Chronic T cell-mediated Disease

Mitochondrial Permeability Transition Pore in Inflammatory Apoptosis of Human Conjunctival Epithelial Cells and T Cells: Effect of Cyclosporin A

Plasmacytoid Dendritic Cells are the Primary Source of IFN-α During the Immunopathogenesis of Desiccating Stress-Induced Dry Eye Disease

Potential Regulatory T Cell Mechanisms Of Immune Suppression In A Mouse Model Of Dry Eye

Molecular Mechanisms of Inflammatory Apoptosis of Conjunctival Epithelial Cells and T cells: Effect of Cyclosporin A (CsA)

Mice with Desiccating Stress-Induced Dry Eye Develop Trigeminal Neuralgia, Despite Decreased Corneal Sensitivity and Nerve Fiber Degeneration

Protective Effect of Carnosic Acid, a Pro-Electrophilic Compound, in Models of Oxidative Stress and Light-Induced Retinal Degeneration

Autoantibodies Contribute to the Immunopathogenesis of Experimental Dry Eye Disease

Plasmacytoid Dendritic Cells are Modulated During the Immunopathogenesis of Desiccating Stress-Induced Experimental Dry Eye

Cyclosporin A (CsA) Induces T Cell Apoptosis and Protects Human Conjunctival Epithelial Cells (IOBA-NHC) from Stress-Induced Apoptosis via Modulation of the Mitochondria Permeability Transition Pore (MPTP)

Alterations in Corneal Nerve Fiber Density and Pain Markers during the Progression of Desiccating Stress-Induced Dry Eye Disease

Treatment of Experimental Anterior and Intermediate Uveitis by a Dexamethasone Intravitreal Implant

The Role Of Ocular Pigmentation In The Intraocular Pressure Response To Brimonidine In Rabbits

Experimental CNV in Cynomolgus Monkeys after Sustained Release of VEGF and bFGF within the Suprachoroidal Space: Part 2. Natural History

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