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Retina February 2025

Targeted Microperimetry Grids for Focal Lesions in Intermediate AMD: PINNACLE Study Report 7

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Stefan Futterknecht; Philipp Anders; Julia Mai; Sophie Riedl; Ursula Hall; Chrysoula Gabrani; Kristina Pfau; Martin J. Menten; Daniel Rueckert; A. Toby Prevost; Hrvoje Bogunovic; Lars G. Fritsche; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew Lotery; Hendrik P. N. Scholl; Maximilian Pfau
TAGS: drusen, study report, vision, eye, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):6. https://doi.org/10.1167/iovs.66.2.6

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Evaluating the distribution of fundus autofluorescence phenotypes in a large, European intermediate AMD cohort and describing a novel phenotype (A PINNACLE Study Report)

Tom Taylor; Rebecca Anne Kaye; Julia Mai; Lars Fritsche; Toby Prevost; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew Lotery

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2266.

ARVO Annual Meeting Abstract June 2024

Patient-tailored Microperimetry Grids for Focal Lesions in Intermediate AMD: A PINNACLE Study Report

Stefan Futterknecht; Maximilian Pfau; Philipp Anders; Julia Mai; Ursula Hall; Hrvoje Bogunovic; Lars Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew Lotery; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4386.

ARVO Annual Meeting Abstract June 2024

Using adaptive optics to assess hyporeflective clumps as a biomarker for progression to cRORA in the PINNACLE study

Christopher Holmes; Naomi Wijesingha; Syed Ahmer Raza; Tom Taylor; Ahmed Hagag; Sophie Riedl; Julia Mai; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Lars Fritsche; Andrew Lotery; Sobha Sivaprasad

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3264.

ARVO Annual Meeting Abstract June 2024

OCT-based AI-assisted phenotyping of intermediate AMD in the prospective PINNACLE trial

Sophie Riedl; Julia Mai; Simon Schürer-Waldheim; Georg Faustmann; Hrvoje Bogunovic; Lars Fritsche; Toby Prevost; Daniel Rueckert; Hendrik P Scholl; Sobha Sivaprasad; Andrew Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):980.

Retina August 2023

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

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Philipp Anders; Ghislaine L. Traber; Maximilian Pfau; Sophie Riedl; Ahmed M. Hagag; Hanna Camenzind; Julia Mai; Rebecca Kaye; Hrvoje Bogunović; Lars G. Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J. Lotery; Hendrik P. N. Scholl
TAGS: age-related macular degeneration, study report, visual acuity, software
Trans. Vis. Sci. Tech.. 2023; 12(8):21. https://doi.org/10.1167/tvst.12.8.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Deciphering hypereflective foci in age related macular degeneration using adaptive optics in the PINNACLE Study

Christopher Holmes; Syed Ahmer Raza; Ahmed M Hagag; Thomas Taylor; Sophie Riedl; Julia Mai; Toby Prevost; Daniel Rueckert; Hrvoje Bogunovic; Hendrik P Scholl; Ursula Schmidt-Erfurth; Lars G Fritsche; Andrew J Lotery; Sobha Sivaprasad

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2171.

ARVO Annual Meeting Abstract June 2023

Self-supervised machine learning for individual prediction of conversion to neovascular AMD in PINNACLE study

Arunava Chakravarty; Taha Emre; Oliver Leingang; Sophie Riedl; Julia Mai; Hendrik P Scholl; Sobha Sivaprasad; Lars G Fritsche; Daniel Rueckert; Andrew J Lotery; Ursula Schmidt-Erfurth; Hrvoje Bogunovic

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):545.

ARVO Annual Meeting Abstract June 2023

Deep learning-based detection of advanced AMD on retinal OCT from the UK Biobank dataset on behalf of the PINNACLE Consortium

Oliver Leingang; Hrvoje Bogunovic; Gregor Sebastian Reiter; Arunava Chakravarty; Martin Joseph Menten; Robert Holland; Lars G Fritsche; Hendrik P Scholl; Daniel Rueckert; Sobha Sivaprasad; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):544.

ARVO Annual Meeting Abstract June 2023

Regional Variation of Retinal Sensitivity in Intermediate AMD in the PINNACLE study

Philipp Anders; Ghislaine L Traber; Maximilian Pfau; Sophie Riedl; Julia Mai; Hanna Camenzind; Chrysoula Gabrani; Rebecca Kaye; Toby Prevost; Hrvoje Bogunovic; Lars G Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J Lotery; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4328.

ARVO Annual Meeting Abstract June 2022

Automated detection of morphologic changes on SD-OCT leading toward outer retinal atrophy in intermediate age-related macular degeneration in the prospective PINNACLE trial

Sophie Riedl; Wolf-Dieter Vogl; Oliver Leingang; Hrvoje Bogunovic; Lars Fritsche; Toby Prevost; Daniel Rueckert; Hendrik P Scholl; Sobha Sivaprasad; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2319.

ARVO Annual Meeting Abstract June 2022

Discovery of imaging biomarkers for healthy aging and age-related macular degeneration using counterfactual generative adversarial networks

Martin Joseph Menten; Oliver Leingang; Hrvoje Bogunovic; Robbie Holland; Ahmed M Hagag; Rebecca Kaye; Sophie Riedl; Ghislaine Traber; Lars Fritsche; Toby Prevost; Hendrik P Scholl; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Daniel Rueckert; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3855.

ARVO Annual Meeting Abstract June 2022

Adaptive optics phenotypes of intermediate age-related macular degeneration

Ahmed M Hagag; Sophie Riedl; Toby Prevost; Lars Fritsche; Daniel Rueckert; Hendrik P Scholl; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2322.

ARVO Annual Meeting Abstract June 2022

Risk factors for progression of intermediate age-related macular degeneration: A systematic review and meta-analysis

Andrew J Lotery; Ahmed M Hagag; Rebecca Kaye; Sophie Riedl; Vy Hoang; Philipp Anders; Christian Appenzeller-Herzog; Ursula Schmidt-Erfurth; Hendrik P Scholl; Toby Prevost; Lars Fritsche; Daniel Rueckert; Sobha Sivaprasad; Ghislaine Traber; Beth Stuart

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2530 – A0099.

ARVO Annual Meeting Abstract June 2022

Investigation of intermediate AMD with MAIA microperimetry metrics by the PINNACLE Consortium

Philipp Anders; Ghislaine L Traber; Ahmed M Hagag; Sophie Riedl; Lars Fritsche; Daniel Rueckert; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew J Lotery; Hendrik P Scholl

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):876.

ARVO Annual Meeting Abstract June 2022

Self-supervised pretraining enables deep learning-based classification of AMD with fewer annotations

Robbie Holland; Martin Joseph Menten; Oliver Leingang; Hrvoje Bogunovic; Ahmed M Hagag; Rebecca Kaye; Sophie Riedl; Ghislaine Traber; Lars Fritsche; Toby Prevost; Hendrik P Scholl; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Daniel Rueckert; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3004 – F0274.

ARVO Annual Meeting Abstract June 2022

Automated deep learning-based AMD stage detection in real-world OCT datasets

Oliver Leingang; Hrvoje Bogunovic; Sophie Riedl; Arunava Chakravarty; Martin Joseph Menten; Robbie Holland; Ghislaine L Traber; Lars Fritsche; Toby Prevost; Hendrik P Scholl; Daniel Rueckert; Sobha Sivaprasad; Andrew J Lotery; Ursula Schmidt-Erfurth

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2106 – F0095.

ARVO Annual Meeting Abstract June 2021

Cluster analysis and phenotype-genotype assessment of geographic atrophy secondary to age-related macular degeneration in the Age-Related Eye Disease Study 2

Tiarnan D L Keenan; Neal L Oden; Elvira Agron; Traci E Clemons; Alice Henning; Lars Fritsche; Wai T Wong; Emily Y Chew

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2942.

Genetics December 2020

The Effect of Genetic Variants Associated With Age-Related Macular Degeneration Varies With Age

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Tina Schick; Laura Lorés-Motta; Lebriz Altay; Lars G. Fritsche; Anneke I. den Hollander; Sascha Fauser

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):17. https://doi.org/10.1167/iovs.61.14.17

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Integrative functional genomics of age-related macular degeneration

Rinki Ratnapriya; Kayode Sosina; Margaret Starostik; Madeline Kwicklis; Rebecca J Kapphahn; Ashley Walton; Alexandra Pietraszkiewicz; Sandra Rocio Montezuma; Lars Fritsche; Emily Y. Chew; Goncalo R. Abecasis; Deborah A. Ferrington; Nilanjan Chatterjee; Anand Swaroop

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6025.

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Targeted Microperimetry Grids for Focal Lesions in Intermediate AMD: PINNACLE Study Report 7

Evaluating the distribution of fundus autofluorescence phenotypes in a large, European intermediate AMD cohort and describing a novel phenotype (A PINNACLE Study Report)

Patient-tailored Microperimetry Grids for Focal Lesions in Intermediate AMD: A PINNACLE Study Report

Using adaptive optics to assess hyporeflective clumps as a biomarker for progression to cRORA in the PINNACLE study

OCT-based AI-assisted phenotyping of intermediate AMD in the prospective PINNACLE trial

Comparison of Novel Volumetric Microperimetry Metrics in Intermediate Age-Related Macular Degeneration: PINNACLE Study Report 3

Deciphering hypereflective foci in age related macular degeneration using adaptive optics in the PINNACLE Study

Self-supervised machine learning for individual prediction of conversion to neovascular AMD in PINNACLE study

Deep learning-based detection of advanced AMD on retinal OCT from the UK Biobank dataset on behalf of the PINNACLE Consortium

Regional Variation of Retinal Sensitivity in Intermediate AMD in the PINNACLE study

Automated detection of morphologic changes on SD-OCT leading toward outer retinal atrophy in intermediate age-related macular degeneration in the prospective PINNACLE trial

Discovery of imaging biomarkers for healthy aging and age-related macular degeneration using counterfactual generative adversarial networks

Adaptive optics phenotypes of intermediate age-related macular degeneration

Risk factors for progression of intermediate age-related macular degeneration: A systematic review and meta-analysis

Investigation of intermediate AMD with MAIA microperimetry metrics by the PINNACLE Consortium

Self-supervised pretraining enables deep learning-based classification of AMD with fewer annotations

Automated deep learning-based AMD stage detection in real-world OCT datasets

Cluster analysis and phenotype-genotype assessment of geographic atrophy secondary to age-related macular degeneration in the Age-Related Eye Disease Study 2

The Effect of Genetic Variants Associated With Age-Related Macular Degeneration Varies With Age

Integrative functional genomics of age-related macular degeneration

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