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Anatomy and Pathology/Oncology November 2024

Novel Uveal Melanoma Patient-Derived Organoid Models Recapitulate Human Disease to Support Translational Research

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Lauren A. Dalvin; Cynthia M. Andrews-Pfannkoch; David R. Miley; Tara L. Hogenson; Samantha A. Erickson; Shivani Malpotra; Kjersten J. Anderson; Mohammed E. Omer; Luciana L. Almada; Cheng Zhang; Hu Li; Diva R. Salomao; Carol L. Shields; Sara E. Lally; Rachel M. Malsch; James A. Armitage; Heather L. Holmes; Michael F. Romero; Michael P. Fautsch; Svetomir N. Markovic; Martin E. Fernandez-Zapico
TAGS: intraocular melanoma, neoplasms, organoids, translational research, immunohistochemistry, bap1 gene, transplantation, heterologous, atac trial
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):60. https://doi.org/10.1167/iovs.65.13.60

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Transcriptional analysis and metabolic characterization of uveal melanoma suggest an altered epigenome.

Piotr Kopinski; Anna Ligezka; David Miley; Samantha Erickson; Ewa Morava; Tamas Kozicz; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2264.

ARVO Annual Meeting Abstract June 2024

Clinical features and outcomes of melanoma presenting with concurrent eyelid and conjunctival involvement

Boyoung Michelle Kim; Robert A Churchill; Caroline Y Yu; Kenny Y Wang; Andrea A Tooley; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2253.

ARVO Annual Meeting Abstract June 2024

Characterization of the Living Library for Uveal Melanoma and Feasibility as a Tool for Drug Screening

Lauren A Dalvin; David Miley; Cynthia Pfannkoch; Samantha Erickson; Shivani Malpotra

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4274.

ARVO Annual Meeting Abstract June 2024

Epidemiology and Clinical Characteristics of Ocular Adnexal Neoplasms using a Population-Based Method

Timothy T Xu; Kenny Y Wang; Launia J White; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4105.

ARVO Annual Meeting Abstract June 2024

Clinical Characteristics and Outcomes of Ocular Sebaceous Cell Carcinoma

Rachel Israilevich; Caroline Y Yu; Anna Mueller; Lauren A Dalvin; Andrea A Tooley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4094.

ARVO Annual Meeting Abstract June 2024

Clinical characteristics and outcomes of primary orbital lymphoma

Kenny Yo Wang; Boyoung Michelle Kim; Caroline Y Yu; Grant M Welk; Robert A Churchill; Launia J White; Lauren A Dalvin; Andrea A Tooley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4110.

ARVO Annual Meeting Abstract June 2023

Multimodal imaging risk factors predictive of small choroidal melanocytic lesion growth to melanoma: An educational study and pictorial guide

Trisha Yuuno Castillo Pecoraro; Robert Churchill; Andrea A. Tooley; Odette Houghton; Arman Mashayekhi; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):897.

ARVO Annual Meeting Abstract June 2023

Impact of phosphoinositide 3-kinase (PI3K) and protein kinase C (PKC) inhibition on uveal melanoma viability and downstream gene expression

David R Miley; Cynthia Pfannkoch; Sam Adams Erickson; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):916.

ARVO Annual Meeting Abstract June 2023

Uveal melanoma cells exhibit variable growth patterns and distinct mitochondrial respiration profile compared with primary human uveal melanocytes.

Piotr K Kopinski; Anna N Ligezka; Tamas Kozicz; Eva Morava; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):914.

ARVO Annual Meeting Abstract June 2023

Transcriptomic and exomic sequencing analysis of the living library for uveal melanoma

Cynthia Pfannkoch; Sam Adams Erickson; David R Miley; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):913.

ARVO Annual Meeting Abstract June 2023

Predictive Value of the International Classification of Diseases, 9 th Revision Codes for Identifying Ocular Oncology Diagnoses

Timothy T Xu; Launia J White; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3605.

ARVO Annual Meeting Abstract June 2022

Population-based Incidence of Ocular Tumors in a Midwestern U.S. Population

Timothy T Xu; Kafayat A Oyemade; Johanny L Lopez Dominguez; Mihai G Dumbrava; Launia J White; David O Hodge; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3139 – A0034.

ARVO Annual Meeting Abstract June 2022

MEK inhibition reduces expression of transcription factor early growth response-1 (EGR1) in BRAF mutant and BRAF wild type melanoma

Cynthia Andrews-Pfannkoch; David R Miley; Jose S Pulido; Samantha Adams; Alan D Marmorstein; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3580 – A0009.

ARVO Annual Meeting Abstract June 2022

Mitochondrial and epigenomic gene transcription analysis in uveal melanoma

Piotr K Kopinski; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3576 – A0005.

ARVO Annual Meeting Abstract June 2022

Optical Coherence Tomography Findings in Choroidal Melanoma-Associated Subretinal Fluid

Melis Kabaalioglu Guner; Timothy W Olsen; Lauren A Dalvin

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2344 – A0013.

ARVO Annual Meeting Abstract June 2022

The role of early growth response-1 in uveal melanoma viability and treatment resistance to MEK inhibition

Lauren A Dalvin; Cynthia Andrews-Pfannkoch; Jose S Pulido; David R Miley; Samantha Adams

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1462.

Articles February 2021

White Paper on Ophthalmic Imaging for Choroidal Nevus Identification and Transformation into Melanoma

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Carol L. Shields; Sara E. Lally; Lauren A. Dalvin; Mandeep S. Sagoo; Marco Pellegrini; Swathi Kaliki; Ahmet Kaan Gündüz; Minoru Furuta; Prithvi Mruthyunjaya; Adrian T. Fung; Jay S. Duker; Sara M. Selig; Antonio Yaghy; Sandor R. Ferenczy; Malvina B. Eydelman; Mark S. Blumenkranz
TAGS: melanoma, nevus, nevus of choroid, ophthalmic imaging
Trans. Vis. Sci. Tech.. 2021; 10(2):24. https://doi.org/10.1167/tvst.10.2.24

Methods December 2020

Optical Path Redirection Device for Optical Coherence Tomography Angiography of Recumbent Patients Under General Anesthesia

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Lucas A. Iezzi; Lauren A. Dalvin

Trans. Vis. Sci. Tech.. 2020; 9(13):45. https://doi.org/10.1167/tvst.9.13.45

ARVO Annual Meeting Abstract June 2020

Risk factors for tumor recurrence following primary intravenous chemotherapy (chemoreduction) for retinoblastoma in 869 eyes of 551 patients

Lauren A Dalvin; Zeynep Bas; Sameeksha Tadepalli; Raksha Rao; Carol L Shields

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2809.

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Novel Uveal Melanoma Patient-Derived Organoid Models Recapitulate Human Disease to Support Translational Research

Transcriptional analysis and metabolic characterization of uveal melanoma suggest an altered epigenome.

Clinical features and outcomes of melanoma presenting with concurrent eyelid and conjunctival involvement

Characterization of the Living Library for Uveal Melanoma and Feasibility as a Tool for Drug Screening

Epidemiology and Clinical Characteristics of Ocular Adnexal Neoplasms using a Population-Based Method

Clinical Characteristics and Outcomes of Ocular Sebaceous Cell Carcinoma

Clinical characteristics and outcomes of primary orbital lymphoma

Multimodal imaging risk factors predictive of small choroidal melanocytic lesion growth to melanoma: An educational study and pictorial guide

Impact of phosphoinositide 3-kinase (PI3K) and protein kinase C (PKC) inhibition on uveal melanoma viability and downstream gene expression

Uveal melanoma cells exhibit variable growth patterns and distinct mitochondrial respiration profile compared with primary human uveal melanocytes.

Transcriptomic and exomic sequencing analysis of the living library for uveal melanoma

Predictive Value of the International Classification of Diseases, 9 th Revision Codes for Identifying Ocular Oncology Diagnoses

Population-based Incidence of Ocular Tumors in a Midwestern U.S. Population

MEK inhibition reduces expression of transcription factor early growth response-1 (EGR1) in BRAF mutant and BRAF wild type melanoma

Mitochondrial and epigenomic gene transcription analysis in uveal melanoma

Optical Coherence Tomography Findings in Choroidal Melanoma-Associated Subretinal Fluid

The role of early growth response-1 in uveal melanoma viability and treatment resistance to MEK inhibition

White Paper on Ophthalmic Imaging for Choroidal Nevus Identification and Transformation into Melanoma

Optical Path Redirection Device for Optical Coherence Tomography Angiography of Recumbent Patients Under General Anesthesia

Risk factors for tumor recurrence following primary intravenous chemotherapy (chemoreduction) for retinoblastoma in 869 eyes of 551 patients

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