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ARVO Annual Meeting Abstract June 2021

Cone mosaic integrity in choroideremia following gene augmentation via subretinal injection of AAV2- hCHM

Jessica Ijams Wolfing Morgan; Yu You Jiang; Leona W Serrano; Denise J Pearson; Jean Bennett; Albert M Maguire; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):47. doi:

ARVO Annual Meeting Abstract June 2020

Multi-modal adaptive optics imaging in GUCA1A -associated autosomal dominant cone-rod dystrophy

Yu You Jiang; Erin O'Neil; Leona Serrano; Denise J. Pearson; Jean Bennett; Tomas Aleman; Jessica Ijams Wolfing Morgan

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):214. doi:

ARVO Annual Meeting Abstract June 2020

Short-term assessment of subfoveal injection of AAV2- hCHM gene augmentation in Choroideremia using adaptive optics ophthalmoscopy

Jessica Ijams Wolfing Morgan; Yu You Jiang; Leona Serrano; Denise J. Pearson; Jean Bennett; Albert Maguire; Tomas Aleman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1130. doi:

ARVO Annual Meeting Abstract June 2020

Detailed Phenotype of Autoimmune Retinopathies with Electroretinography, Multimodal-Imaging and Visual Psychophysics

Yafeng Li; Leona Serrano; Erin O'Neil; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2099. doi:

ARVO Annual Meeting Abstract June 2020

Natural History of Rod and Cone Photoreceptor Dysfunction in Choroideremia

Kurt Scavelli; Erin O'Neil; Leona Serrano; Denise J. Pearson; Jessica Ijams Wolfing Morgan; Albert Maguire; Jean Bennett; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3027. doi:

ARVO Annual Meeting Abstract June 2020

Treatment Potential for LCA5 -associated Leber Congenital Amaurosis

Katherine E. Uyhazi; Puya Aravand; Brent A. Bell; Zhangyong Wei; Lanfranco Leo; Leona Serrano; Denise J. Pearson; Ivan Shpylchak; Jennifer Pham; Vidyullatha Vasireddy; Jean Bennett; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4500. doi:

Retina May 2020

Treatment Potential for LCA5 -Associated Leber Congenital Amaurosis

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Katherine E. Uyhazi; Puya Aravand; Brent A. Bell; Zhangyong Wei; Lanfranco Leo; Leona W. Serrano; Denise J. Pearson; Ivan Shpylchak; Jennifer Pham; Vidyullatha Vasireddy; Jean Bennett; Tomas S. Aleman
TAGS: electroretinography, leber's amaurosis, mice, photoreceptors, tissue degeneration, eye, injections, retina, spectral domain-optical coherence tomography, excipients
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):30. doi: https://doi.org/10.1167/iovs.61.5.30

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Structural Correlates of Short-wavelength and Normalized Near-infrared Fundus Autofluorescence Imaging in Choroideremia.

Drew Scoles; Kurt Scavelli; Leona Serrano; Katherine E Uyhazi; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1864. doi:

ARVO Annual Meeting Abstract July 2019

Structural and Functional Abnormalities in Leber Congenital Amaurosis Caused by Mutations in RDH12: A Short-Term Longitudinal Study

Katherine E. Uyhazi; Leona Serrano; Grace Vergilio; Denise J Pearson; Albert M. Maguire; Jean Bennett; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4509. doi:

ARVO Annual Meeting Abstract July 2019

Structural Markers Predictive of Visual Acuity in Choroideremia

Kurt Scavelli; Drew Scoles; Leona Serrano; Katherine E. Uyhazi; Jessica Ijams Wolfing Morgan; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4523. doi:

ARVO Annual Meeting Abstract July 2019

AAV2- hCHM Subretinal Delivery to the Macula in Choroideremia: 2 year Results of an Ongoing Phase I/II Gene Therapy Trial

Tomas S Aleman; Rachel M Huckfeldt; Leona Serrano; Grace Vergilio; Denise J Pearson; Katherine E. Uyhazi; Sarah McCague; Kathleen Marshall; Daniel C Chung; Emily Liu; Eric A Pierce; Jessica Ijams Wolfing Morgan; Jean Bennett; Dean Eliott; Jason Comander; Albert M. Maguire

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5173. doi:

Retina October 2018

RDH12 Mutations Cause a Severe Retinal Degeneration With Relatively Spared Rod Function

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Tomas S. Aleman; Katherine E. Uyhazi; Leona W. Serrano; Vidyullatha Vasireddy; Scott J. Bowman; Michael J. Ammar; Denise J. Pearson; Albert M. Maguire; Jean Bennett
TAGS: mutation, retina, retinal degeneration, rod photoreceptors, spectral domain-optical coherence tomography, pathophysiology
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5225-5236. doi: https://doi.org/10.1167/iovs.18-24708

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Early Structural and Functional Abnormalities in Leber Congenital Amaurosis Caused by Mutations in RDH12

Tomas S Aleman; Katherine E Uyhazi; Leona Serrano; Scott J Bowman; Denise J Pearson; Albert M Maguire; Jean Bennett

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):46. doi:

Visual Neuroscience July 2018

Comparing Clinical Perimetry and Population Receptive Field Measures in Patients with Choroideremia

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Edward H. Silson; Tomas S. Aleman; Aimee Willett; Leona W. Serrano; Denise J. Pearson; Andreas M. Rauschecker; Albert M. Maguire; Chris I. Baker; Jean Bennett; Manzar Ashtari
TAGS: prolactin-releasing hormone, visual fields, choroideremia, perimetry
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3249-3258. doi: https://doi.org/10.1167/iovs.18-23929

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Frequent subclinical macular changes in melanoma patients treated with combined BRAF/MEK inhibition and high dose hydroxychloroquine does not require dosing modification or discontinuation: preliminary results from a multi-institutional phase I/II clinical treatment trial for advanced metastatic BRAF mutant melanoma

Leona Serrano; Harpal Sandhu; Elaine Zhou; Delu Song; Tara Gangadhar; Lynn Schuchter; Sheryl Mitnick; Janice Mehnert; Ann Silk; Leonel Hernandez Aya; Alexander Huang; Gerald Linette; Ravi K Amaravadi; Benjamin J Kim; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):255. doi:

ARVO Annual Meeting Abstract June 2017

AAV2- hCHM Subretinal Delivery to the Macula in Choroideremia: Preliminary Six Month Safety Results of an Ongoing Phase I/II Gene Therapy Trial

Tomas S Aleman; Leona Serrano; Grace K. Han; Denise J Pearson; Sarah McCague; Kathleen A Marshall; Daniel C Chung; Emily Liu; Jessica Ijams Wolfing Morgan; Jean Bennett; Albert M Maguire

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4485. doi:

ARVO Annual Meeting Abstract September 2016

Natural History of the Central Structural Abnormalities in Choroideremia: Insights from a Cross-sectional Study

Anastasia Traband; Nicole Fuerst; Leona Serrano; Grace K. Han; Denise Pearson; Katherine Uyhazi; Jessica Ijams Wolfing Morgan; Jean Bennett; Albert M Maguire; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6587. doi:

ARVO Annual Meeting Abstract September 2016

Cone Photoreceptor Inner and Outer Segment Mosaic Abnormalities in Choroideremia

Jessica Ijams Wolfing Morgan; Grace K. Han; Robert F. Cooper; Denise Pearson; Leona Serrano; Jean Bennett; Albert M Maguire; Alfredo Dubra; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5112. doi:

Retina December 2015

Cobalamin C Deficiency Shows a Rapidly Progressing Maculopathy With Severe Photoreceptor and Ganglion Cell Loss

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Lucas Bonafede; Can H. Ficicioglu; Leona Serrano; Grace Han; Jessica I. W. Morgan; Monte D. Mills; Brian J. Forbes; Stefanie L. Davidson; Gil Binenbaum; Paige B. Kaplan; Charles W. Nichols; Patrick Verloo; Bart P. Leroy; Albert M. Maguire; Tomas S. Aleman
TAGS: cobalamin, ganglia, macular disorders, photoreceptors, retina, retinal degeneration, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):7875-7887. doi: https://doi.org/10.1167/iovs.15-17857

Includes: Supplemental Content

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Cone mosaic integrity in choroideremia following gene augmentation via subretinal injection of AAV2- hCHM

Multi-modal adaptive optics imaging in GUCA1A -associated autosomal dominant cone-rod dystrophy

Short-term assessment of subfoveal injection of AAV2- hCHM gene augmentation in Choroideremia using adaptive optics ophthalmoscopy

Detailed Phenotype of Autoimmune Retinopathies with Electroretinography, Multimodal-Imaging and Visual Psychophysics

Natural History of Rod and Cone Photoreceptor Dysfunction in Choroideremia

Treatment Potential for LCA5 -associated Leber Congenital Amaurosis

Treatment Potential for LCA5 -Associated Leber Congenital Amaurosis

Structural Correlates of Short-wavelength and Normalized Near-infrared Fundus Autofluorescence Imaging in Choroideremia.

Structural and Functional Abnormalities in Leber Congenital Amaurosis Caused by Mutations in RDH12: A Short-Term Longitudinal Study

Structural Markers Predictive of Visual Acuity in Choroideremia

AAV2- hCHM Subretinal Delivery to the Macula in Choroideremia: 2 year Results of an Ongoing Phase I/II Gene Therapy Trial

RDH12 Mutations Cause a Severe Retinal Degeneration With Relatively Spared Rod Function

Early Structural and Functional Abnormalities in Leber Congenital Amaurosis Caused by Mutations in RDH12

Comparing Clinical Perimetry and Population Receptive Field Measures in Patients with Choroideremia

AAV2- hCHM Subretinal Delivery to the Macula in Choroideremia: Preliminary Six Month Safety Results of an Ongoing Phase I/II Gene Therapy Trial

Natural History of the Central Structural Abnormalities in Choroideremia: Insights from a Cross-sectional Study

Cone Photoreceptor Inner and Outer Segment Mosaic Abnormalities in Choroideremia

Cobalamin C Deficiency Shows a Rapidly Progressing Maculopathy With Severe Photoreceptor and Ganglion Cell Loss

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