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ARVO Annual Meeting Abstract June 2022

Clinical Ocular Exposure Extrapolation Using PBPK Modeling and Simulation: Moxifloxacin Solution Case Study

Maxime Le Merdy; Viera Lukacova; Ming-Liang Tan; Andrew Babiskin; Liang Zhao

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2121 – F0137. doi:

Retina July 2021

Hypertensive Retinopathy and the Risk of Stroke Among Hypertensive Adults in China

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Xuling Chen; Lishun Liu; Mengyi Liu; Xiao Huang; Ying Meng; Haicheng She; Liang Zhao; Jing Zhang; Yadi Zhang; Xiaopeng Gu; Xianhui Qin; Yan Zhang; Jianping Li; Xiping Xu; Binyan Wang; Fan Fan Hou; Genfu Tang; Rongfeng Liao; Yong Huo; Jun Li; Liu Yang
TAGS: cerebrovascular accident, china, hypertension, hypertensive retinopathy, ischemic stroke, retinal diseases, stroke risk, adult
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):28. doi: https://doi.org/10.1167/iovs.62.9.28

Includes: Supplemental Content

Cornea April 2020

Extended Contact Lens Wear Promotes Corneal Norepinephrine Secretion and Pseudomonas aeruginosa Infection in Mice

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Jie Li; Xiubin Ma; Lianghui Zhao; Ya Li; Qingjun Zhou; Xianli Du
TAGS: contact lenses, cornea, infections, keratitis, mice, norepinephrine, pseudomonas aeruginosa infections, bodily secretions, biofilms, capillary leak syndrome
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):17. doi: https://doi.org/10.1167/iovs.61.4.17

ARVO Annual Meeting Abstract July 2019

Microglia Repopulation Ameliorates Aging Phenotypes in Retinal Microglia and Neurons

Lian Zhao; Jorge Cueva Vargas; Jennifer Liao; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2797. doi:

ARVO Annual Meeting Abstract July 2019

Sustained Depletion of Choroidal Macrophages is Associated with Choroidal Vascular Atrophy and RPE Disorganization

Xiao Yang; Lian Zhao; Maria M Campos; Mones S Abu-Asab; Davide Ortolan; Nathan Hotaling; Kapil Bharti; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5239. doi:

ARVO Annual Meeting Abstract July 2018

Genetic ablation of TGFbR2 in microglia results in neuroinflammatory and neurodegenerative changes in the retina

Wenxin Ma; Sean Silverman; Lian Zhao; Rafael Villasmil; Robert N Fariss; Maria M Campos; Juan Amaral; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2530. doi:

ARVO Annual Meeting Abstract July 2018

C3 deficiency results in accelerated rod photoreceptor loss in a mouse model of retinitis pigmentosa

Sean Silverman; Wenxin Ma; Lian Zhao; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3944. doi:

ARVO Annual Meeting Abstract June 2017

CXCL13, an aging-related microglial-derived cytokine, promotes epithelial-mesenchymal transformation (EMT) in RPE cells

Wenxin Ma; Lian Zhao; Lijin Dong; Maria M Campos; Robert N Fariss; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5375. doi:

ARVO Annual Meeting Abstract June 2017

Tamoxifen provides structural and functional rescue in murine models of photoreceptor degeneration

Xu Wang; Lian Zhao; Wenxin Ma; Yikui Zhang; Shaimar Gonzalez; Jianguo Fan; Friedrich Kretschmer; Tudor C Badea; Haohua Qian; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5901. doi:

ARVO Annual Meeting Abstract June 2017

Microglia homeostasis in the adult mouse retina: restoration of microglial distribution, morphology, and function following acute depletion

Yikui Zhang; Lian Zhao; Xu Wang; Wenxin Ma; Adam Lazere; Haohua Qian; Robert N Fariss; Jun Zhang; Mones S Abu-Asab; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):806. doi:

ARVO Annual Meeting Abstract June 2017

Fabrication of a micellar supramolecular hydrogel for ocular drug delivery

zhao liang zhang; Hao Chen; Xing Yi Li

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1076. doi:

ARVO Annual Meeting Abstract September 2016

Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina

Xu Wang; Lian Zhao; Jun Zhang; Robert N Fariss; Wenxin Ma; Friedrich Kretschmer; Minhua Wang; Haohua Qian; Tudor C Badea; Jerome E Roger; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Microglia specialization in the primate macula: Changes in distribution and morphology with retinal position and aging.

Janani Singaravelu; Lian Zhao; Robert N Fariss; T Michael Nork; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2230. doi:

ARVO Annual Meeting Abstract September 2016

CX3CR1 deficiency affects microglial phagocytosis in rd10 retinal degeneration

Lian Zhao; Matthew Zabel; Yikui Zhang; Shaimar Gonzalez; Wenxin Ma; Xu Wang; Robert N Fariss; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2267. doi:

ARVO Annual Meeting Abstract September 2016

Repopulation of the retina by myeloid cells following depletion of endogenous retinal microglia in adult mice

Yikui Zhang; Lian Zhao; Xu Wang; Robert N Fariss; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4185. doi:

ARVO Annual Meeting Abstract September 2016

Role of the Fas death receptor in light-damage induced photoreceptor degeneration

Edward Linton; Chenguang Wang; Delu Song; Liangliang Zhao; Ying Song; Jeff Jamison; John Freshley; David N Zacks; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5797. doi:

Retinal Cell Biology August 2015

CD1 Mouse Retina Is Shielded From Iron Overload Caused by a High Iron Diet

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Devang L. Bhoiwala; Ying Song; Alyssa Cwanger; Esther Clark; Liang-liang Zhao; Chenguang Wang; Yafeng Li; Delu Song; Joshua L. Dunaief
TAGS: iron, mice, diet, retina, iron overload, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5344-5352. doi: https://doi.org/10.1167/iovs.15-17026

ARVO Annual Meeting Abstract June 2015

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration

Matthew Zabel; Lian Zhao; Xu Wang; Wenxin Ma; Robert N Fariss; Haohua Qian; Christopher Parkhurst; Wen-Biao Gan; Wai T Wong

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2587. doi:

ARVO Annual Meeting Abstract June 2015

High iron diet causes elevation of retinal iron levels and RPE autofluorescence

Devang Bhoiwala; Ying Song; Alyssa Cwanger; Esther Clark; Liangliang Zhao; Chenguang Wang; Yafeng Li; Delu Song; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4203. doi:

Retinal Cell Biology September 2014

Systemic Administration of the Antioxidant/Iron Chelator α-Lipoic Acid Protects Against Light-Induced Photoreceptor Degeneration in the Mouse Retina

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Liangliang Zhao; Chenguang Wang; Delu Song; Yafeng Li; Ying Song; Guanfang Su; Joshua L. Dunaief
TAGS: antioxidants, iron chelating agents, mice, photoreceptors, retina, saline solutions, thioctic acid, tissue degeneration, rna, messenger, in situ nick-end labeling
Invest. Ophthalmol. Vis. Sci.. 2014; 55(9):5979-5988. doi: https://doi.org/10.1167/iovs.14-15025

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Clinical Ocular Exposure Extrapolation Using PBPK Modeling and Simulation: Moxifloxacin Solution Case Study

Hypertensive Retinopathy and the Risk of Stroke Among Hypertensive Adults in China

Extended Contact Lens Wear Promotes Corneal Norepinephrine Secretion and Pseudomonas aeruginosa Infection in Mice

Microglia Repopulation Ameliorates Aging Phenotypes in Retinal Microglia and Neurons

Sustained Depletion of Choroidal Macrophages is Associated with Choroidal Vascular Atrophy and RPE Disorganization

Genetic ablation of TGFbR2 in microglia results in neuroinflammatory and neurodegenerative changes in the retina

C3 deficiency results in accelerated rod photoreceptor loss in a mouse model of retinitis pigmentosa

CXCL13, an aging-related microglial-derived cytokine, promotes epithelial-mesenchymal transformation (EMT) in RPE cells

Tamoxifen provides structural and functional rescue in murine models of photoreceptor degeneration

Microglia homeostasis in the adult mouse retina: restoration of microglial distribution, morphology, and function following acute depletion

Fabrication of a micellar supramolecular hydrogel for ocular drug delivery

Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina

Microglia specialization in the primate macula: Changes in distribution and morphology with retinal position and aging.

CX3CR1 deficiency affects microglial phagocytosis in rd10 retinal degeneration

Repopulation of the retina by myeloid cells following depletion of endogenous retinal microglia in adult mice

Role of the Fas death receptor in light-damage induced photoreceptor degeneration

CD1 Mouse Retina Is Shielded From Iron Overload Caused by a High Iron Diet

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration

High iron diet causes elevation of retinal iron levels and RPE autofluorescence

Systemic Administration of the Antioxidant/Iron Chelator α-Lipoic Acid Protects Against Light-Induced Photoreceptor Degeneration in the Mouse Retina

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