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Perspective February 2022

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

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Colleen M. McDowell; Krishnakumar Kizhatil; Michael H. Elliott; Darryl R. Overby; Joseph van Batenburg-Sherwood; J. Cameron Millar; Markus H. Kuehn; Gulab Zode; Ted S. Acott; Michael G. Anderson; Sanjoy K. Bhattacharya; Jacques A. Bertrand; Terete Borras; Diane E. Bovenkamp; Lin Cheng; John Danias; Michael Lucio De Ieso; Yiqin Du; Jennifer A. Faralli; Rudolf Fuchshofer; Preethi S. Ganapathy; Haiyan Gong; Samuel Herberg; Humberto Hernandez; Peter Humphries; Simon W. M. John; Paul L. Kaufman; Kate E. Keller; Mary J. Kelley; Ruth A. Kelly; David Krizaj; Ajay Kumar; Brian C. Leonard; Raquel L. Lieberman; Paloma Liton; Yutao Liu; Katy C. Liu; Navita N. Lopez; Weiming Mao; Timur Mavlyutov; Fiona McDonnell; Gillian J. McLellan; Philip Mzyk; Andrews Nartey; Louis R. Pasquale; Gaurang C. Patel; Padmanabhan P. Pattabiraman; Donna M. Peters; Vijaykrishna Raghunathan; Ponugoti Vasantha Rao; Naga Rayana; Urmimala Raychaudhuri; Ester Reina-Torres; Ruiyi Ren; Douglas Rhee; Uttio Roy Chowdhury; John R. Samples; E. Griffen Samples; Najam Sharif; Joel S. Schuman; Val C. Sheffield; Cooper H. Stevenson; Avinash Soundararajan; Preeti Subramanian; Chenna Kesavulu Sugali; Yang Sun; Carol B. Toris; Karen Y. Torrejon; Amir Vahabikashi; Janice A. Vranka; Ting Wang; Colin E. Willoughby; Chen Xin; Hongmin Yun; Hao F. Zhang; Michael P. Fautsch; Ernst R. Tamm; Abbot F. Clark; C. Ross Ethier; W. Daniel Stamer
TAGS: eye, mice, ocular hypertension, intraocular pressure, perfusion
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):12. doi: https://doi.org/10.1167/iovs.63.2.12

Articles January 2022

Archetypal Analysis Reveals Quantifiable Patterns of Visual Field Loss in Optic Neuritis

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Elena Solli; Hiten Doshi; Tobias Elze; Louis Pasquale; Michael Wall; Mark Kupersmith
TAGS: antithymoglobulin, arterial tortuosity syndrome, blindness, body weight, datasets, deep learning, eye, optic neuritis, periodic paralysis, potassium-sensitive cardiodysrhythmic type, visual field defects
Trans. Vis. Sci. Tech.. 2022; 11(1):27. doi: https://doi.org/10.1167/tvst.11.1.27

Includes: Supplemental Content

Articles August 2021

Unsupervised Machine Learning Identifies Quantifiable Patterns of Visual Field Loss in Idiopathic Intracranial Hypertension

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Hiten Doshi; Elena Solli; Tobias Elze; Louis R. Pasquale; Michael Wall; Mark J. Kupersmith
TAGS: antithymoglobulin, arterial tortuosity syndrome, blindness, body weight, datasets, eye, periodic paralysis, potassium-sensitive cardiodysrhythmic type, pseudotumor cerebri, unsupervised machine learning, visual field defects
Trans. Vis. Sci. Tech.. 2021; 10(9):37. doi: https://doi.org/10.1167/tvst.10.9.37

Includes: Supplemental Content

Articles August 2021

Development of Primary Open Angle Glaucoma-Like Features in a Rhesus Macaque Colony From Southern China

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Louis R. Pasquale; Li Gong; Janey L. Wiggs; Lingzhen Pan; Zhenyan Yang; Mingling Wu; Zunyuan Yang; Dong Feng Chen; Wen Zeng
TAGS: cercopithecidae, glaucoma, macaca mulatta, open-angle glaucoma, intraocular pressure, china
Trans. Vis. Sci. Tech.. 2021; 10(9):20. doi: https://doi.org/10.1167/tvst.10.9.20

Includes: Supplemental Content

Articles August 2021

Estimating the Severity of Visual Field Damage From Retinal Nerve Fiber Layer Thickness Measurements With Artificial Intelligence

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Xiaoqin Huang; Jian Sun; Juleke Majoor; Koenraad Arndt Vermeer; Hans Lemij; Tobias Elze; Mengyu Wang; Michael Vincent Boland; Louis Robert Pasquale; Vahid Mohammadzadeh; Kouros Nouri-Mahdavi; Chris Johnson; Siamak Yousefi
TAGS: retinal nerve fiber layer, visual fields, glaucoma, artificial intelligence, datasets, eye
Trans. Vis. Sci. Tech.. 2021; 10(9):16. doi: https://doi.org/10.1167/tvst.10.9.16

Articles June 2021

Development and Comparison of Machine Learning Algorithms to Determine Visual Field Progression

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Osamah Saeedi; Michael V. Boland; Loris D'Acunto; Ramya Swamy; Vikram Hegde; Surabhi Gupta; Amin Venjara; Joby Tsai; Jonathan S. Myers; Sarah R. Wellik; Gustavo DeMoraes; Louis R. Pasquale; Lucy Q. Shen; Yangjiani Li; Tobias Elze
TAGS: glaucoma, machine learning, visual fields, eye, datasets
Trans. Vis. Sci. Tech.. 2021; 10(7):27. doi: https://doi.org/10.1167/tvst.10.7.27

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Archetypal Analysis of Visual Fields in Optic Neuritis Reveals Functional Biomarkers Associated with Outcome and Treatment Response

Elena Solli; Hiten Doshi; Tobias Elze; Louis Pasquale; Michael Wall; Mark J Kupersmith

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2101. doi:

ARVO Annual Meeting Abstract June 2021

Novel Genetic Factors Associated with Primary Open-Angle Glaucoma Identified Using Artificial Intelligence

Siamak Yousefi; Krati Gupta; Jian sun; Xiaoqin Huang; Louis Pasquale; Lu Lu; Robert Williams

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1491. doi:

ARVO Annual Meeting Abstract June 2021

Association of patient race and Hispanic ethnicity with age and severity of glaucomatous vision loss at first visit

Qingying Jin; Omar Halawa; Nazlee Zebardast; Louis Pasquale; Jae H Kang; Alice Carlyle Lorch; Lucia Sobrin; Joan W Miller; Yangjiani Li; Mohammad Eslami; Mengyu Wang; Tobias Elze

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3536. doi:

ARVO Annual Meeting Abstract June 2021

Detecting Glaucoma Progression using Deep Archetypal Analysis of Retinal Nerve Fiber Layer Thickness Measurements

Sidharth Mahotra; Xiaoqin Huang; Tobias Elze; Mengyu Wang; Michael V Boland; Louis Pasquale; Juleke Eugenie Anne Majoor; Koenraad Arndt Vermeer; Hans Lemij; Kouros Nouri-Mahdavi; Chris A Johnson; Siamak Yousefi

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3357. doi:

ARVO Annual Meeting Abstract June 2021

Detection of Glaucoma Progression from Retinal Nerve Fiber Layer Thickness Measurements Using Machine Learning

Xiaoqin Huang; Sidharth Mahotra; Tobias Elze; Mengyu Wang; Michael V. Boland; Louis Pasquale; Juleke Eugenie Anne Majoor; Hans Lemij; Kouros Nouri-Mahdavi; Chris A Johnson; Siamak Yousefi

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1005. doi:

ARVO Annual Meeting Abstract June 2021

Association of Non-Melanoma Skin Cancer with Exfoliation Syndrome: The Utah Project of Exfoliation Syndrome

Christian James Pompoco; Chase Paulson; Samuel C. Taylor; Brian Craig Stagg; Robert Ritch; Jae H Kang; Janey L Wiggs; Louis R Pasquale; Karen Curtin; Barbara M Wirostko

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):71. doi:

ARVO Annual Meeting Abstract June 2021

Unsupervised Machine Learning Identifies Relevant Patterns of Loss, and Quantifies Response to Treatment in Visual Fields from Eyes with Idiopathic Intracranial Hypertension

Hiten Doshi; Elena Solli; Tobias Elze; Louis R Pasquale; Michael Wall; Mark J Kupersmith

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2394. doi:

ARVO Annual Meeting Abstract June 2021

Automated Machine Learning vs. Inception for the Autonomous Detection of Disc Hemorrhage

Aaron C Brown; Henry Cousins; Clara Cousins; Nisha Chadha; Kateki Vinod; Alon Harris; Fotis Topouzis; Vassilis Kilintzis; Michael Coote; Louis R Pasquale

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2133. doi:

ARVO Annual Meeting Abstract June 2021

An autonomous algorithm shows that African and Hispanic Americans with primary open-angle glaucoma present with severe visual field loss patterns

Louis R Pasquale; Jae H Kang; Bernard Rosner; Janey L Wiggs; Mengyu Wang; Tobias Elze

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3499. doi:

ARVO Annual Meeting Abstract June 2021

Effect of Dietary Modification on Incident Open-Angle Glaucoma in a Randomized Trial

Rajvi Mehta; Roberta Ray; Louis R Pasquale; Pauline M Maki; Mary N Haan; Rebecca Jackson; Thasarat S Vajaranant

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1612. doi:

ARVO Annual Meeting Abstract June 2021

Spatial Patterns of Preclinical Visual Fields in Glaucoma

Eun Young Choi; Lucy Q Shen; Louis R Pasquale; Michael V Boland; Pradeep Y Ramulu; Sarah W Wellik; C Gustavo De Moraes; Jonathan S. Myers; Siamak Yousefi; Peter Bex; Yangjiani Li; Mohammad Eslami; Tobias Elze; Mengyu Wang

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1007. doi:

ARVO Annual Meeting Abstract June 2021

Artificial Intelligence Assessment of Optic Cup Shape Patterns in Glaucoma

Mengyu Wang; Lucy Q Shen; Louis R Pasquale; Thao D. Nguyen; Yangjiani Li; Mohammad Eslami; Chhavi Saini; Nazlee Zebardast; Tobias Elze

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3359. doi:

ARVO Annual Meeting Abstract June 2021

Differences in retinal capillary blood flow and visual function in healthy male and female subjects of African and European descent

Brent A Siesky; Alon Harris; Nicholas Kalafatis; Louis R Pasquale; Aditya Belamkar; Joshua D. Shin; Ingrida Januleviciene; Giovanna Guidoboni; Alice Chandra Verticchio Vercellin

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):548. doi:

ARVO Annual Meeting Abstract June 2021

Associations between Large Optic Nerve Cupping, Related Genetic Risk Scores and Cognitive function

Sasha Kravets; Rawan Allozi; Louis R Pasquale; Mark A Espeland; Steve R Rapp; Barbara E. K. Klein; Stacy M Meuer; Mary N Haan; Pauline M Maki; Joelle Hallak; Thasarat S Vajaranant

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1589. doi:

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Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

Archetypal Analysis Reveals Quantifiable Patterns of Visual Field Loss in Optic Neuritis

Unsupervised Machine Learning Identifies Quantifiable Patterns of Visual Field Loss in Idiopathic Intracranial Hypertension

Development of Primary Open Angle Glaucoma-Like Features in a Rhesus Macaque Colony From Southern China

Estimating the Severity of Visual Field Damage From Retinal Nerve Fiber Layer Thickness Measurements With Artificial Intelligence

Development and Comparison of Machine Learning Algorithms to Determine Visual Field Progression

Archetypal Analysis of Visual Fields in Optic Neuritis Reveals Functional Biomarkers Associated with Outcome and Treatment Response

Novel Genetic Factors Associated with Primary Open-Angle Glaucoma Identified Using Artificial Intelligence

Association of patient race and Hispanic ethnicity with age and severity of glaucomatous vision loss at first visit

Detecting Glaucoma Progression using Deep Archetypal Analysis of Retinal Nerve Fiber Layer Thickness Measurements

Detection of Glaucoma Progression from Retinal Nerve Fiber Layer Thickness Measurements Using Machine Learning

Association of Non-Melanoma Skin Cancer with Exfoliation Syndrome: The Utah Project of Exfoliation Syndrome

Unsupervised Machine Learning Identifies Relevant Patterns of Loss, and Quantifies Response to Treatment in Visual Fields from Eyes with Idiopathic Intracranial Hypertension

Automated Machine Learning vs. Inception for the Autonomous Detection of Disc Hemorrhage

An autonomous algorithm shows that African and Hispanic Americans with primary open-angle glaucoma present with severe visual field loss patterns

Effect of Dietary Modification on Incident Open-Angle Glaucoma in a Randomized Trial

Spatial Patterns of Preclinical Visual Fields in Glaucoma

Artificial Intelligence Assessment of Optic Cup Shape Patterns in Glaucoma

Differences in retinal capillary blood flow and visual function in healthy male and female subjects of African and European descent

Associations between Large Optic Nerve Cupping, Related Genetic Risk Scores and Cognitive function

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