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Perspective March 2021

Artificial Intelligence to Reduce Ocular Health Disparities: Moving From Concept to Implementation

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John P. Campbell; Ciku Mathenge; Hunter Cherwek; Konstantinos Balaskas; Louis R. Pasquale; Pearse A. Keane; Michael F. Chiang; on behalf of the American Academy of Ophthalmology Task Force on Artificial Intelligence
TAGS: artificial intelligence, blindness, diabetic retinopathy, health disparity, implementation science, ophthalmology, screening, technology, glaucoma, refractive errors
Trans. Vis. Sci. Tech.. 2021; 10(3):19. doi: https://doi.org/10.1167/tvst.10.3.19

Articles November 2020

Inter-Eye Association of Visual Field Defects in Glaucoma and Its Clinical Utility

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Bettina Teng; Dian Li; Eun Young Choi; Lucy Q. Shen; Louis R. Pasquale; Michael V. Boland; Pradeep Ramulu; Sarah R. Wellik; Carlos Gustavo De Moraes; Jonathan S. Myers; Siamak Yousefi; Thao Nguyen; Yuying Fan; Hui Wang; Peter J. Bex; Tobias Elze; Mengyu Wang

Trans. Vis. Sci. Tech.. 2020; 9(12):22. doi: https://doi.org/10.1167/tvst.9.12.22

Includes: Supplemental Content

Articles August 2020

An Artificial Intelligence Approach to Assess Spatial Patterns of Retinal Nerve Fiber Layer Thickness Maps in Glaucoma

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Mengyu Wang; Lucy Q. Shen; Louis R. Pasquale; Hui Wang; Dian Li; Eun Young Choi; Siamak Yousefi; Peter J. Bex; Tobias Elze
TAGS: artificial intelligence, glaucoma, maps, retinal nerve fiber layer, eye
Trans. Vis. Sci. Tech.. 2020; 9(9):41. doi: https://doi.org/10.1167/tvst.9.9.41

Includes: Supplemental Content

ARVO Imaging in the Eye Conference Abstract July 2020

Determining retinal nerve fiber layer thickness vulnerability zones in mild glaucoma with rescaled optic nerve heads

Raymond C S Wong; Mikhail Startsev; Yangjiani Li; Eun Young Choi; Dian Li; Lucy Shen; Louis Pasquale; Gadi Wollstein; Hiroshi Ishikawa; Joel Schuman; Mengyu Wang; Tobias Elze

Invest. Ophthalmol. Vis. Sci.. 2020; 61(9):PB005. doi:

Special Issue July 2020

Protecting Data Privacy in the Age of AI-Enabled Ophthalmology

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Elysse Tom; Pearse A. Keane; Marian Blazes; Louis R. Pasquale; Michael F. Chiang; Aaron Y. Lee; Cecilia S. Lee; and AAO Artificial Intelligence Task Force
TAGS: ophthalmology, privacy, datasets
Trans. Vis. Sci. Tech.. 2020; 9(2):36. doi: https://doi.org/10.1167/tvst.9.2.36

Genetics July 2020

Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

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Milica A. Margeta; Sophia M. Letcher; Robert P. Igo, Jr.; Jessica N. Cooke Bailey; Louis R. Pasquale; Jonathan L. Haines; Oleg Butovsky; Janey L. Wiggs; for the NEIGHBORHOOD consortium
TAGS: apolipoprotein e, glaucoma, open-angle glaucoma, trem2 gene, alleles
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):3. doi: https://doi.org/10.1167/iovs.61.8.3

ARVO Annual Meeting Abstract June 2020

Calcium Channel Blocker Use and Risk of Glaucoma in a Large United Kingdom Population

Alan Kastner; Giovanni Montesano; C Gustavo De Moraes; Jae H. Kang; Janey Wiggs; Louis Pasquale; Pirro G Hysi; Sharon Chua; Praveen J Patel; Paul J Foster; Sir Peng T. Khaw; Anthony Khawaja

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2739. doi:

ARVO Annual Meeting Abstract June 2020

Analysis of ATXN2 trinucleotide repeats in primary open angle glaucoma patients

Shi Song Rong; Robert Igo; Jessica Cooke Bailey; Jonathan L Haines; Louis Pasquale; Janey Wiggs

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1247. doi:

ARVO Annual Meeting Abstract June 2020

Clinical utility of the artificial intelligence enabled dashboard for glaucoma monitoring

Siamak Yousefi; Tobias Elze; Louis Pasquale; Osamah Saeedi; Mengyu Wang; Lucy Shen; Sara Wellik; C Gustavo De Moraes; Jonathan S Myers; Michael V Boland

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4526. doi:

ARVO Annual Meeting Abstract June 2020

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

Janey Wiggs; Puya Gharahkhani; Eric Jorgenson; Pirro G Hysi; Anthony Khawaja; Sarah Pendergrass; Xikun Han; David Mackey; Christopher Hammond; Michael A Hauser; Louis R Pasquale; Caroline Klaver; Michiaki Kubo; Tin Aung; Jamie E Craig; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1890. doi:

ARVO Annual Meeting Abstract June 2020

Evidence for a causal link between pseudoexfoliation syndrome and myocardial infarction using Mendelian randomization

Marianne T Kennedy Neary; Oliver J Kennedy; George Davey Smith; Pirro G Hysi; Louis R Pasquale; Janey Wiggs; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2738. doi:

ARVO Annual Meeting Abstract June 2020

Association of coffee, tea, and caffeine consumption with intraocular pressure and interaction with genetic risk: findings from the UK Biobank

Jihye Kim; Hugues Aschard; Jae H. Kang; Marleen AH Lentjes; Janey Wiggs; Anthony Khawaja; Louis R Pasquale

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):52. doi:

ARVO Annual Meeting Abstract June 2020

Integrative Prioritization of IOP-associated Genes Using High Throughput Genomic Data

Yutao Liu; Emily Parker; Hannah Youngblood; Jingwen Cai; Kristin Marie Perkumas; Janey Wiggs; Louis R Pasquale; Michael A Hauser; Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):990. doi:

ARVO Annual Meeting Abstract June 2020

Glaucoma Examination in the Amish of Holmes County, Ohio

Jonathan Mikal Skarie; Tyler G Kinzy; Jane Sewell; Yeunjoo E Song; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Sherri Hochstetler; Louis R Pasquale; Janey Wiggs; Jonathan L Haines; Jessica Cooke Bailey

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1252. doi:

ARVO Annual Meeting Abstract June 2020

Inter-Eye Symmetries of Visual Field Defects in Glaucoma

Bettina Teng; Dian Li; Lucy Shen; Louis R Pasquale; Michael V Boland; Pradeep Y Ramulu; Sara Wellik; Carlos Gustavo De Moraes; Jonathan S Myers; Siamak Yousefi; Thao D Nguyen; Eun Young Choi; Hui Wang; Peter J Bex; Tobias Elze; Mengyu Wang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4047. doi:

ARVO Annual Meeting Abstract June 2020

Intraocular pressure and retinal blood flow regulation: a mathematical model to understand the role of the retinal veins

Alice Chandra Verticchio Vercellin; Alon Harris; Nicholas Marazzi; Louis R Pasquale; Brent A Siesky; Ingrida Januleviciene; Giovanna Guidoboni

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1738. doi:

ARVO Annual Meeting Abstract June 2020

Determining aligned retinal nerve fiber layer thickness (RNFLT) vulnerability zones in mild glaucoma

Raymond C S Wong; Mikhail Startsev; Yangjiani Li; Eun Young Choi; Dian Li; Lucy Shen; Louis R Pasquale; Gadi Wollstein; Hiroshi Ishikawa; Joel S Schuman; Mengyu Wang; Tobias Elze

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1970. doi:

ARVO Annual Meeting Abstract June 2020

The Effect of Latanoprostene Bunod on Nailfold Capillary Blood Flow in Patients with Primary Open-Angle Glaucoma.

Siddharth Bhargava; Margot Gardin; Emily Seo; Michael E Seleski; Joon Sub Lee; Erica B. Jacobs; Ahmad Najafi; Louis R Pasquale; Robert Ritch

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3487. doi:

ARVO Annual Meeting Abstract June 2020

History of UV-related keratinocytic carcinomas is increased in patients with exfoliation syndrome

Jeff Huang; Erica B. Jacobs; Emily Seo; Harriet O Lloyd; Kateki Vinod; Tak Yee Tania Tai; Nisha Chadha; Sumayya Ahmad; Douglas Buxton; Robert Ritch; Louis R Pasquale

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):62. doi:

ARVO Annual Meeting Abstract June 2020

The Prevalence of Primary Open-Angle Glaucoma-Like Features in a Rhesus Macaque Colony from Southern China

Louis R Pasquale; Li Gong; Janey Wiggs; Lingzhen Pan; Zhenyan Yang; Mingling Wu; Dongfeng Chen; Wen Zeng

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1436. doi:

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Artificial Intelligence to Reduce Ocular Health Disparities: Moving From Concept to Implementation

Inter-Eye Association of Visual Field Defects in Glaucoma and Its Clinical Utility

An Artificial Intelligence Approach to Assess Spatial Patterns of Retinal Nerve Fiber Layer Thickness Maps in Glaucoma

Determining retinal nerve fiber layer thickness vulnerability zones in mild glaucoma with rescaled optic nerve heads

Protecting Data Privacy in the Age of AI-Enabled Ophthalmology

Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

Calcium Channel Blocker Use and Risk of Glaucoma in a Large United Kingdom Population

Analysis of ATXN2 trinucleotide repeats in primary open angle glaucoma patients

Clinical utility of the artificial intelligence enabled dashboard for glaucoma monitoring

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

Evidence for a causal link between pseudoexfoliation syndrome and myocardial infarction using Mendelian randomization

Association of coffee, tea, and caffeine consumption with intraocular pressure and interaction with genetic risk: findings from the UK Biobank

Integrative Prioritization of IOP-associated Genes Using High Throughput Genomic Data

Glaucoma Examination in the Amish of Holmes County, Ohio

Inter-Eye Symmetries of Visual Field Defects in Glaucoma

Intraocular pressure and retinal blood flow regulation: a mathematical model to understand the role of the retinal veins

Determining aligned retinal nerve fiber layer thickness (RNFLT) vulnerability zones in mild glaucoma

The Effect of Latanoprostene Bunod on Nailfold Capillary Blood Flow in Patients with Primary Open-Angle Glaucoma.

History of UV-related keratinocytic carcinomas is increased in patients with exfoliation syndrome

The Prevalence of Primary Open-Angle Glaucoma-Like Features in a Rhesus Macaque Colony from Southern China

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