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ARVO Annual Meeting Abstract June 2020

Development of 3D retinal grafts for the treatment of retinal degenerative blindness

Laura R Bohrer; Ian C Han; Jessica A Cooke; Erin R Burnight; Arwin Shrestha; Louisa Affatigato; Luke A Wiley; Kristan Worthington; Katherine N Gibson-corley; Robert F Mullins; Edwin M Stone; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2511. doi:

ARVO Annual Meeting Abstract June 2020

Characterization of a Novel Mak- deficient Rat Model of Retinal Degeneration and Phenotype Rescue Using Adeno-Associated Virus-Based Gene Therapy

Ian C Han; Luke A Wiley; Christy L Ralston; Emily E Kaalberg; Mallory J Ulferts; Elizabeth L Kennedy; Robert F Mullins; Edwin M Stone; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):679. doi:

ARVO Annual Meeting Abstract July 2019

Generation of rod- vs. cone-dominant patient-derived 3D retinal grafts for the treatment of retinal degenerative blindness

Laura R. Bohrer; Jessica A. Cooke; Arwin Shrestha; Erin R. Burnight; Kristin R. Anfinson; Malia M. Collins; Robert F Mullins; Edwin M Stone; Kristan S. Worthington; Luke A. Wiley; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2871. doi:

ARVO Annual Meeting Abstract July 2019

Characterizing the immune response to helper-dependent adenovirus in the rat retina.

Luke A. Wiley; Emily E. Kaalberg; Chunhua Jiao; Robert F Mullins; Edwin M Stone; Budd Tucker; Ian Han

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3408. doi:

ARVO Annual Meeting Abstract June 2017

Using pathway-specific reporter and direct conversion constructs to investigate Juvenile Neuronal Ceroid Lipofuscinosis.

Lorenzo L Lones; Erin R Burnight; Dalyz Ochoa; Joseph C Giacalone; Robert A Madumba; Robert F Mullins; Edwin M Stone; Budd Tucker; Luke A Wiley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):263. doi:

ARVO Annual Meeting Abstract June 2017

Two-Photon Polymerization of High-Resolution 3D, Biodegradable Photoreceptor Cell Scaffolds

Kristan Sorenson Worthington; Jessica R. Thompson; Brian J. Green; Spencer J. Bunn; Emily E. Kaalberg; Rebecca M. Johnston; Luke A Wiley; Robert F Mullins; Edwin M Stone; C. Allan Guymon; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3390. doi:

ARVO Annual Meeting Abstract June 2017

The human RPE-choroid in short term organ culture: evaluation of gene expression changes

Robert F Mullins; S Scott Whitmore; Kathleen R Chirco; Grefachew Workalemahu; Shemin Zeng; Adam P DeLuca; XiuYing Liu; Jessica A Penticoff; Luke A Wiley; Edwin M Stone; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):619. doi:

ARVO Annual Meeting Abstract June 2017

Development of corneal endothelial cell-specific reporter constructs and a CRISPR-Cas9 genome editing approach to study Fuchs Dystrophy.

Luke A Wiley; Laura R Bohrer; Erin R Burnight; Elizabeth L Kennedy; Edwin M Stone; Mark A Greiner; Michael D Wagoner; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1444. doi:

ARVO Annual Meeting Abstract June 2017

Characterization and Treatment of RPGR-associated Photoreceptor Disease

Joseph C Giacalone; Luke A Wiley; Erin R Burnight; Jeaneen Andorf; Luan M Streb; Louisa M Affatigato; Cathryn Cranston; Dalyz Ochoa; Robert F Mullins; Budd Tucker; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4515. doi:

ARVO Annual Meeting Abstract June 2017

Transduction of photoreceptors following subretinal injections of AAV5 and helper-dependent adenovirus in human retina ex vivo and pig retina in vivo

Brittni Scruggs; Erin R Burnight; Chunhua Jiao; Luke A Wiley; Robert F Mullins; Edwin M Stone; Budd Tucker; Elliott Sohn

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4534. doi:

ARVO Annual Meeting Abstract September 2016

Development of a step-wise protocol for the generation of human induced pluripotent stem cell-derived choroidal endothelial cells.

Allison E Songstad; Luke A Wiley; Erin R Burnight; S Scott Whitmore; Emily E Kaalberg; Megan J Riker; Edwin M Stone; Robert F Mullins; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1136. doi:

ARVO Annual Meeting Abstract September 2016

CRISPR/Cas9-mediated genome editing for correction of inherited retinal disease mutations.

Erin R Burnight; Luke A Wiley; Adam P DeLuca; Douglas J. Oppedal; Todd E Scheetz; Robert F Mullins; Edwin M Stone; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1157. doi:

ARVO Annual Meeting Abstract September 2016

CRISPR-based Genome Editing for treatment of CEP290 -IVS26-associated Leber Congenital Amaurosis (LCA)

Edwin M Stone; Erin R Burnight; Luke A Wiley; Luan M Streb; Louisa M Affatigato; Jeaneen A Andorf; Robert F Mullins; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Patient-specific iPSCs to investigate pathophysiology and develop treatments for RPGR -associated XLRP

Joseph C Giacalone; Erin R Burnight; Tasneem P Sharma; Luke A Wiley; Dalyz Ochoa; Malia Collins; Robert F Mullins; Budd A Tucker; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Assessing transcriptional diversity of human and mouse photoreceptor cells by single-cell RNA-Seq

S Scott Whitmore; Adam P DeLuca; Luke A Wiley; Erin R Burnight; Miles J Flamme-Wiese; Budd A Tucker; Robert F Mullins; Todd E Scheetz; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4795. doi:

ARVO Annual Meeting Abstract September 2016

Human Retinal Engineering using 3D Two-Photon Polymerization and Chitosan Hydrogels

Kristan S Worthington; Luke A Wiley; Bailey B Banach; Allison E Songstad; Emily E Kaalberg; Robert F Mullins; Edwin M Stone; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5321. doi:

ARVO Annual Meeting Abstract September 2016

HUMAN DISEASE MODELING OF TRNT1 -ASSOCIATED RETINITIS PIGMENTOSA IN PATIENT-DERIVED CELLS

Tasneem P Sharma; Joseph C Giacalone; Erin R Burnight; Luke A Wiley; Jill S Wiley; Robert A Madumba; Robert F Mullins; Edwin M Stone; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6060. doi:

ARVO Annual Meeting Abstract September 2016

Production of clinical-grade patient-specific iPSCs and transplantable photoreceptor precursor cells for the treatment of retinal degenerative blindness.

Budd A Tucker; Luke A Wiley; Erin R Burnight; Kristan S Worthington; Cathryn M Cranston; Kristin R Anfinson; Robert F Mullins; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6064. doi:

ARVO Annual Meeting Abstract September 2016

Modeling Enhanced S-cone Syndrome Using Patient-Specific iPSC-derived Retinal Eyecups

Luke A Wiley; Erin R Burnight; Jennifer A Halder; Jessica A Penticoff; Christine M Haas; Robert F Mullins; Edwin M Stone; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Retinal Cell Biology December 2015

Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration

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Allison E. Songstad; Luke A. Wiley; Khahn Duong; Emily Kaalberg; Miles J. Flamme-Wiese; Cathryn M. Cranston; Megan J. Riker; Dana Levasseur; Edwin M. Stone; Robert F. Mullins; Budd A. Tucker
TAGS: electroconvulsive therapy, computed tomography, endothelial cells, cats, chloramphenicol o-acetyltransferase, coculture techniques, age-related macular degeneration, mice, proteins, chronic exertional compartment syndrome
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8258-8267. doi: https://doi.org/10.1167/iovs.15-17073

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Development of 3D retinal grafts for the treatment of retinal degenerative blindness

Characterization of a Novel Mak- deficient Rat Model of Retinal Degeneration and Phenotype Rescue Using Adeno-Associated Virus-Based Gene Therapy

Generation of rod- vs. cone-dominant patient-derived 3D retinal grafts for the treatment of retinal degenerative blindness

Characterizing the immune response to helper-dependent adenovirus in the rat retina.

Using pathway-specific reporter and direct conversion constructs to investigate Juvenile Neuronal Ceroid Lipofuscinosis.

Two-Photon Polymerization of High-Resolution 3D, Biodegradable Photoreceptor Cell Scaffolds

The human RPE-choroid in short term organ culture: evaluation of gene expression changes

Development of corneal endothelial cell-specific reporter constructs and a CRISPR-Cas9 genome editing approach to study Fuchs Dystrophy.

Characterization and Treatment of RPGR-associated Photoreceptor Disease

Transduction of photoreceptors following subretinal injections of AAV5 and helper-dependent adenovirus in human retina ex vivo and pig retina in vivo

Development of a step-wise protocol for the generation of human induced pluripotent stem cell-derived choroidal endothelial cells.

CRISPR/Cas9-mediated genome editing for correction of inherited retinal disease mutations.

CRISPR-based Genome Editing for treatment of CEP290 -IVS26-associated Leber Congenital Amaurosis (LCA)

Patient-specific iPSCs to investigate pathophysiology and develop treatments for RPGR -associated XLRP

Assessing transcriptional diversity of human and mouse photoreceptor cells by single-cell RNA-Seq

Human Retinal Engineering using 3D Two-Photon Polymerization and Chitosan Hydrogels

HUMAN DISEASE MODELING OF TRNT1 -ASSOCIATED RETINITIS PIGMENTOSA IN PATIENT-DERIVED CELLS

Production of clinical-grade patient-specific iPSCs and transplantable photoreceptor precursor cells for the treatment of retinal degenerative blindness.

Modeling Enhanced S-cone Syndrome Using Patient-Specific iPSC-derived Retinal Eyecups

Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration

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