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ARVO Annual Meeting Abstract June 2024

AMD-associated cystatin C variant impacts RPE differentiation and mitochondrial activity

Ioan Valentin Matei; Tanachapa Jantalika; Daniel Grimes; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1324.

ARVO Annual Meeting Abstract June 2024

The effects of fucoxanthin on ultraviolet A (UVA)-induced oxidative stress in human retinal epithelial cells

Luminita I Paraoan; Gunticha Suwanmanee; Daniel Grimes; Ioan Valentin Matei; Sirikul Manochantr

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1318.

ARVO Annual Meeting Abstract June 2024

Modulation of inflammatory-related signalling by PERP-mediated apoptosis in uveal melanoma cells

Daniel Grimes; Ioan Valentin Matei; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6210.

ARVO Annual Meeting Abstract June 2023

AMD-linked variant B cystatin C interacts with mitochondrial proteins in retinal pigment epithelium cells

Luminita I Paraoan; Emil Carlsson

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):426.

ARVO Annual Meeting Abstract June 2022

Characterisation of phosphorylation sites of PERP and their function in regulation of apoptosis in uveal melanoma

Kaiyue Teng; Ian Prior; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2371 – A0055.

ARVO Annual Meeting Abstract June 2022

Investigating the effect of ageing on protein folding chaperones expression in RPE

Dhanach Dhirachaikulpanich; João Pedro de Magalhães; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3904 – A0106.

ARVO Annual Meeting Abstract June 2021

A transcriptome based computational drug repurposing analysis to target the RPE/choroid abnormality in advanced age-related macular degeneration

Dhanach Dhirachaikulpanich; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):245.

ARVO Annual Meeting Abstract June 2020

Intracellular RPE interactome analysis of protein variants associated with AMD by affinity purification mass spectrometry

Luminita I Paraoan; Umar Sharif; Lewis Kelly; Emil Carlsson

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3688.

ARVO Annual Meeting Abstract July 2019

PERP-ing the points of contact between ER and plasma membrane: modulation of ER stress and apoptosis in uveal melanoma

Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1364.

ARVO Annual Meeting Abstract July 2019

Reduced cystatin C secretion in iPS-derived retinal pigment epithelium cells is associated with altered extracellular matrix adhesion and migration

Emil Carlsson; Wasu Supharattanasitthi; Malcolm Jackson; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4910.

ARVO Annual Meeting Abstract July 2018

Human Retinal Pigment Epithelium Transcriptional Response to Stress Induced by Advanced Glycation End Products and Lipid Peroxidation

Wasu Supharattanasitthi; Joe M. Butler; Arvydas Maminishkis; Yit C. Yang; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2349.

ARVO Annual Meeting Abstract June 2017

Exploring the protein-protein interactions of the p53 apoptosis effector protein PERP

Samantha Jade McDonnell; Ian Prior; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3562.

ARVO Annual Meeting Abstract September 2016

The cysteine proteinase inhibitor cystatin C harbors a haplotype associated with increased risk of AMD and Alzheimer’s disease and decreased plasma levels of its mature form

Luminita I Paraoan; Joe Butler; Nirodhini Narendran; Yit C. Yang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):649.

ARVO Annual Meeting Abstract June 2015

Effects of advanced glycation end-products (AGEs) on retinal pigment epithelial (RPE) cells lysosomal function: implications for age-related macular degeneration (AMD)

Luminita I Paraoan; Umar Sharif; Paul Kay; Ian Grierson; Yit C Yang; Simon Harding

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4197.

ARVO Annual Meeting Abstract April 2014

AGE-related Modulation of Cystatin C Expression, Secretion and Polarity in the Retinal Pigment Epithelium

Luminita I Paraoan; Paul Kay; Paul Hiscott; Arvydas Maminishkis; Yit C Yang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1331.

ARVO Annual Meeting Abstract April 2014

In vitro effect of thrombospondin-1 in ocular surface epithelial cell lines

Laura Soriano-Romaní; Laura Garcia-Posadas; Antonio López-García; Luminita I Paraoan; Yolanda Diebold

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):498.

ARVO Annual Meeting Abstract April 2014

The signal sequence of AMD-related variant Cystatin C is not sufficient for mistrafficking to mitochondria

Alessandro Riccio; Malcolm Jackson; Walter Hunziker; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):630.

ARVO Annual Meeting Abstract April 2014

Cysteine proteases expression and secretion by retinal pigmented epithelium (RPE)

Umar Sharif; Joe Butler; Yit C Yang; Ian Grierson; Simon P Harding; Luminita I Paraoan

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):410.

ARVO Annual Meeting Abstract March 2012

Enhancement Of P53-dependent Pro-Apoptotic Response By Perp In Uveal Melanoma Cells

Luminita I. Paraoan; David Spiller; Michael R. White; Ian Grierson; Lyndsay Davies

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5118.

ARVO Annual Meeting Abstract April 2011

Characterisation of Cystatin C Expression in Human Retinal Pigment Epithelium in Relation to Age

Luminita I. Paraoan; Donna Gray; Ian Grierson; Yit C. Yang; Simon Harding; Paul Hiscott

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2340.

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