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Biochemistry and Molecular Biology December 2024

Sphingolipid Levels and Processing of the Retinyl Chromophore in the Retina of a Mouse Model of Niemann-Pick Disease

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Bushra Rahman; David M. G. Anderson; Chunhe Chen; Jian Liu; Lukasz G. Migas; Raf Van de Plas; Kevin L. Schey; Masahiro Kono; Jie Fan; Yiannis Koutalos
TAGS: chromophore, mice, niemann-pick diseases, retina, sphingolipids, vitamin a, spectrometry, mass, matrix-assisted laser desorption-ionization, sphingomyelins, diagnostic imaging, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):24. https://doi.org/10.1167/iovs.65.14.24

Biochemistry and Molecular Biology July 2024

The First Steps of the Visual Cycle in Human Rod and Cone Photoreceptors

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Chunhe Chen; Leopold Adler, IV; Cole Milliken; Bushra Rahman; Masahiro Kono; Lynn Poole Perry; Federico Gonzalez-Fernandez; Yiannis Koutalos
TAGS: photoreceptors, vertebrate, retinal cone, rod photoreceptors, vitamin a, fluorescence, rhodopsin, eye, kinetics, retina, rate constants
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):9. https://doi.org/10.1167/iovs.65.8.9

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Spontaneous in vitro generation of rhodopsin with all-trans retinal

Anne M Hanneken; Masahiro Kono

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6048.

ARVO Annual Meeting Abstract July 2018

Flavonoid effects on rod and cone opsins

Masahiro Kono; Patrice Goletz; Anne M Hanneken

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4520.

ARVO Annual Meeting Abstract June 2017

Measurements of 11-cis retinal deficiency in human autopsy eyes with macular degeneration.

Anne M Hanneken; Thomas Neikirk; Jennifer Johnson; Masahiro Kono

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5245.

ARVO Annual Meeting Abstract September 2016

A2E adducts in the human retinal pigment epithelium

Masahiro Kono; Zsolt Ablonczy; Patrice W. Goletz; Joe G Hollyfield; Rosalie K Crouch

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1737.

ARVO Annual Meeting Abstract June 2015

Components of human lipofuscin

Masahiro Kono; John E. Oatis; Zsolt Ablonczy; Patrice W. Goletz; Joe G Hollyfield; Rosalie K Crouch

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2381.

ARVO Annual Meeting Abstract March 2012

Thermal isomerization of cone pigments

Masahiro Kono; Patrice W. Goletz

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3361.

ARVO Annual Meeting Abstract March 2012

Acid Sphingomyelinase Deficiency Induces Age-related Degeneration In The Mouse Retina

Bill X. Wu; Jie Fan; Jenkins W. Jenkins; Yiannis Koutalos; Rosalie K. Crouch; Craig E. Crosson; Masahiro Kono; Yusuf A. Hannun

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6886.

ARVO Annual Meeting Abstract April 2011

Effects of Non-retinoid Compounds on Cone Opsin Activity

Masahiro Kono; Patrice W. Goletz

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):59.

ARVO Annual Meeting Abstract April 2011

Cone Opsin Inverse Agonists Promote Light-independent Cone Survival in Chromophore-deficient Mice

Jie Fan; Masahiro Kono

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5454.

ARVO Annual Meeting Abstract April 2011

A Gene Therapy For A Gene Mutation In Human Ips Cell Using Helper-dependent Adenoviral Vector

Tetsu Yoshida; Yoko Ozawa; Haruna Koizumi; Kenya Yuki; Yuka Hirabayashi; Keiichiro Suzuki; Konosuke Mitani; Kazuo Tsubota; Shigeto Shimmura; Hideyuki Okano

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):433.

Retina April 2011

Light Prevents Exogenous 11- cis Retinal from Maintaining Cone Photoreceptors in Chromophore-Deficient Mice

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Jie Fan; Rosalie K. Crouch; Masahiro Kono
TAGS: chromophore, mice, retinal cone, opsin
Invest. Ophthalmol. Vis. Sci.. 2011; 52(5):2412-2416. https://doi.org/10.1167/iovs.10-6437

ARVO Annual Meeting Abstract April 2010

Light Prevents Exogenous 11-cis Retinal From Maintaining Cone Photoreceptors in Chromophore-Deficient Mice

J. Fan; R. K. Crouch; M. Kono

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):2493.

ARVO Annual Meeting Abstract April 2009

Constitutive Activity of Cone Opsins

M. Kono; P. W. Goletz; R. K. Crouch

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):5432.

ARVO Annual Meeting Abstract April 2009

Modulation of Opsin Signaling by Flavonoids

A. M. Hanneken; R. Harris; A. Olson; R. K. Crouch; C. Cornwall; M. Kono

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):2722.

ARVO Annual Meeting Abstract May 2008

11-cis Retinol is a Suitable Substrate for Cone Pigment Regeneration

M. Kono; R. K. Crouch; M. C. Cornwall; P. Ala-Laurila

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):3527.

ARVO Annual Meeting Abstract May 2007

Effects of Noncovalent Binding of the Ring Portion of Retinal on Rod and Cone Opsin Activity

M. Kono

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):3247.

ARVO Annual Meeting Abstract May 2005

Structure and Function of Cone Arrestin: Does Transient Binding to Cone Opsin Contribute to the Speed of Cone Recovery?

V.V. Gurevich; B.R. Sutton; S.A. Vishnivetskiy; D. Raman; J. Robert; S.M. Hanson; J. Navarro; B.E. Knox; M. Kono

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):1176.

ARVO Annual Meeting Abstract May 2005

The Role of the Conserved Counterion Residue in a UV Cone Pigment

M. Kono

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):2987.

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Sphingolipid Levels and Processing of the Retinyl Chromophore in the Retina of a Mouse Model of Niemann-Pick Disease

The First Steps of the Visual Cycle in Human Rod and Cone Photoreceptors

Spontaneous in vitro generation of rhodopsin with all-trans retinal

Flavonoid effects on rod and cone opsins

Measurements of 11-cis retinal deficiency in human autopsy eyes with macular degeneration.

A2E adducts in the human retinal pigment epithelium

Components of human lipofuscin

Thermal isomerization of cone pigments

Acid Sphingomyelinase Deficiency Induces Age-related Degeneration In The Mouse Retina

Effects of Non-retinoid Compounds on Cone Opsin Activity

Cone Opsin Inverse Agonists Promote Light-independent Cone Survival in Chromophore-deficient Mice

A Gene Therapy For A Gene Mutation In Human Ips Cell Using Helper-dependent Adenoviral Vector

Light Prevents Exogenous 11- cis Retinal from Maintaining Cone Photoreceptors in Chromophore-Deficient Mice

Light Prevents Exogenous 11-cis Retinal From Maintaining Cone Photoreceptors in Chromophore-Deficient Mice

Constitutive Activity of Cone Opsins

Modulation of Opsin Signaling by Flavonoids

11-cis Retinol is a Suitable Substrate for Cone Pigment Regeneration

Effects of Noncovalent Binding of the Ring Portion of Retinal on Rod and Cone Opsin Activity

Structure and Function of Cone Arrestin: Does Transient Binding to Cone Opsin Contribute to the Speed of Cone Recovery?

The Role of the Conserved Counterion Residue in a UV Cone Pigment

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