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Immunology and Microbiology July 2025

The Gut Microbial System Responds to Retinal Injury and Modulates the Outcomes by Regulating Innate Immune Activation

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Xuexue Cui; Caijiao Yi; Jian Liu; Jinyan Qi; Wen Deng; Xiangling Yuan; Ruiqi Zhou; Mei Chen; Qiang Xiang; Heping Xu
TAGS: antibiotics, gastrointestinal microbiome, mice, retinal injuries, wounds and injuries, laser injuries, attenuation, lasers
Invest. Ophthalmol. Vis. Sci.. 2025; 66(9):6. https://doi.org/10.1167/iovs.66.9.6

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2025

Deep Learning-based Image Quality Assessment for Optical Coherence Tomography

Hemanth Machavaram; Derrek Hibar; Mike Chen; Alessandra Valcarcel; Vivide Chang; Thomas Albrecht; Daniela Ferrara; Huanxiang Lu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5418.

ARVO Annual Meeting Abstract June 2025

Automated Segmentation of Diabetic Retinopathy (DR) Lesions on Color Fundus Photographs (CFP) Using Deep Learning

Dimitrios Damopoulos; Hemanth Machavaram; Eric Gros; Matthew McLeod; Ales Neubert; Felix Yang; Mike Chen; Siva Balasubramanian; Fethallah Benmansour

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):566.

ARVO Annual Meeting Abstract June 2025

The integrin-mediated focal adhesion is critically involved in the macrophage-to-myofibroblast transition in subretinal fibrosis

Wen Deng; Caijiao Yi; Jian Liu; JinYan Qi; Xuexue Cui; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5540.

ARVO Annual Meeting Abstract June 2025

Association between socioeconomic status and neovascular age-related macular degeneration outcomes

Rohini Dasan; Mike Chen; Jeanette Du; Brian Do; Mohsin Ali

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):296.

ARVO Annual Meeting Abstract June 2025

In Vivo Study of a Novel Photoacoustic Epiretinal Prosthesis

mi zheng; Van Nguyen; Maomao Chen; Hyunwoo Song; Alexandra Patterson; Chad Weiler; James Spicer; Seth Billings; Emad Boctor; Yannis Paulus

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2445.

ARVO Annual Meeting Abstract June 2025

Intraocular and circulating immune cell inflammasome activation in neovascular age-related macular degeneration

Heping Xu; Judith Lechner; Wen Deng; Shazna Bi; Nan Yang; Zhongping Chen; Julie Silvestri; Usha Chakravarthy; Mei Chen

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2643.

ARVO Annual Meeting Abstract June 2025

Modeling the ocular secondary astigmatism in toric patient population

Minghan Chen

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):62.

ARVO Annual Meeting Abstract June 2025

Effect of blocking inflammatory cytokine TNF-α in a model for macular fibrosis in age-related macular degeneration

David Hughes; Nina Zippel; Juergen Prestle; Heike Neubauer; Heping Xu; Mei Chen

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):749.

ARVO Annual Meeting Abstract June 2025

Circadian rhythms of retinal microglia in early diabetes

Varun Pathak; Hanagh Winter; Mei Chen; Eleni Beli; Alan W Stitt

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4804.

ARVO Annual Meeting Abstract June 2025

The gut microbiota senses retinal injury, regulates inflammation and participates in retinal wound healing – identifying the retina-to-gut axis

Xuexue Cui; Caijiao Yi; Jian Liu; JinYan Qi; Wen Deng; Xiangling Yuan; Ruiqi Zhou; Mei Chen; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4615.

ARVO Annual Meeting Abstract June 2025

The Impact of Age on Healthy Human Tear Film - A Pilot Study

Alice Chandra Verticchio Vercellin; Richard B Rosen; Paul A Sidoti; Brent A Siesky; Keren Wood; Nathan Schanzer; Tania Tai; Masako Chen; Kira Manusis; Katy Tai; Brenner J. David; Norman J. Kleiman; Francesco Oddone; Carmela Carnevale; Gal Antman

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6091.

ARVO Annual Meeting Abstract June 2025

Repeatability Study for Retinal Optical Coherence Tomography (OCT) Segmentation Algorithms (ROSA) in neovascular age-related macular degeneration (nAMD)

Thomas Albrecht; Derrek Hibar; Mike Chen; Vivide Chang; Daniela Ferrara; Huanxiang Lu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):578.

ARVO Annual Meeting Abstract June 2025

PER-001, an endothelin antagonist, increased optic nerve head blood flow with structural and functional improvements in patients with glaucoma

Steven L Mansberger; James Paauw; Sevgi Gurkan; Michelle Chen; Dale Usner; Phillip Chi Lai

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3322.

ARVO Annual Meeting Abstract June 2025

Got1 and Got2 Deficiency Demonstrate Opposing Effects on Rod Photoreceptor Metabolism, Function and Survival

Meini Chen; Shubha Subramanya; Moloy T Goswami; Heather Hager; Nicholas Miller; Eric Weh; Sraboni Chaudhury; Peter Sajjakulnukit; Katherine Weh; Costas A Lyssiotis; Thomas J Wubben

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3232.

ARVO Annual Meeting Abstract June 2025

Development of a 3D-printed Conduit for Promoting Optic Nerve Repair and Regeneration via Chronic Glutamate Signaling

Karen Chang; Kin-Sang Cho; Sheng-Hao Hsu; Tien-Li Ma; Jhih-Guang Wu; Zicheng Yu; Ajay Ashok; Tor Paaske Utheim; Min-Huey Chen; Wei-Fang Su; Dongfeng Chen

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4945.

ARVO Annual Meeting Abstract June 2025

Effects of air pollutants on human trabecular meshwork cells

Andrew C Jubintoro; Evonne Chau; Vansh K Goel; Dhruvi Mehta; Sarah K Yang; Harriet M Chen; Ken Kitayama; Anne L. Coleman; Jie J Zheng

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):208.

ARVO Annual Meeting Abstract June 2025

Dropless vitrectomy surgery for epiretinal membranes; Efficacy and safety compared to standard of care

Anny M.S. Cheng; K V Chalam; Marib Akanda

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2251.

ARVO Annual Meeting Abstract June 2025

Automated Deep Learning Classification of the Quality of Slit-Lamp Photographs of Microbial Keratitis

Joshua Ong; Ming-Chen Lu; Chanon Thanitcul; Mercy Pawar; Jenna N Hart; Emily Vogt; Sina Farsiu; Yiqing Wang; Pauline Dmitriev; Angela Gupta; Nambi Nallasamy; Maria A Woodward

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4436.

ARVO Annual Meeting Abstract June 2025

Validation of Suprachoroidal Drug Delivery in Humans Using Ultrasound Biomicroscopy and a Custom-Designed Needle

K V Chalam; Marib Akanda; Anny M.S. Cheng

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5504.

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The Gut Microbial System Responds to Retinal Injury and Modulates the Outcomes by Regulating Innate Immune Activation

Deep Learning-based Image Quality Assessment for Optical Coherence Tomography

Automated Segmentation of Diabetic Retinopathy (DR) Lesions on Color Fundus Photographs (CFP) Using Deep Learning

The integrin-mediated focal adhesion is critically involved in the macrophage-to-myofibroblast transition in subretinal fibrosis

Association between socioeconomic status and neovascular age-related macular degeneration outcomes

In Vivo Study of a Novel Photoacoustic Epiretinal Prosthesis

Intraocular and circulating immune cell inflammasome activation in neovascular age-related macular degeneration

Modeling the ocular secondary astigmatism in toric patient population

Effect of blocking inflammatory cytokine TNF-α in a model for macular fibrosis in age-related macular degeneration

Circadian rhythms of retinal microglia in early diabetes

The gut microbiota senses retinal injury, regulates inflammation and participates in retinal wound healing – identifying the retina-to-gut axis

The Impact of Age on Healthy Human Tear Film - A Pilot Study

Repeatability Study for Retinal Optical Coherence Tomography (OCT) Segmentation Algorithms (ROSA) in neovascular age-related macular degeneration (nAMD)

PER-001, an endothelin antagonist, increased optic nerve head blood flow with structural and functional improvements in patients with glaucoma

Got1 and Got2 Deficiency Demonstrate Opposing Effects on Rod Photoreceptor Metabolism, Function and Survival

Development of a 3D-printed Conduit for Promoting Optic Nerve Repair and Regeneration via Chronic Glutamate Signaling

Effects of air pollutants on human trabecular meshwork cells

Dropless vitrectomy surgery for epiretinal membranes; Efficacy and safety compared to standard of care

Automated Deep Learning Classification of the Quality of Slit-Lamp Photographs of Microbial Keratitis

Validation of Suprachoroidal Drug Delivery in Humans Using Ultrasound Biomicroscopy and a Custom-Designed Needle

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