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Retina September 2008

Influence of a Quantitative Trait Locus on Mouse Chromosome 19 to the Light-Adapted Electroretinogram

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Alison L. Reynolds; Michael Danciger; G. Jane Farrar; Peter Humphries; Paul F. Kenna
TAGS: electroretinography, mice, quantitative trait loci, chromosomes, human, pair 19
Invest. Ophthalmol. Vis. Sci.. 2008; 49(9):4058-4063. doi: https://doi.org/10.1167/iovs.07-1620

Biochemistry and Molecular Biology July 2008

Genetic Modifiers of Retinal Degeneration in the rd3 Mouse

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Michael Danciger; Diego Ogando; Haidong Yang; Michael T. Matthes; Nicole Yu; Kelly Ahern; Douglas Yasumura; Robert W. Williams; Matthew M. LaVail
TAGS: genetics, mice, retinal degeneration, quantitative trait loci, genes
Invest. Ophthalmol. Vis. Sci.. 2008; 49(7):2863-2869. doi: https://doi.org/10.1167/iovs.08-1715

ARVO Annual Meeting Abstract May 2008

Genetic Modifiers of rd3 Retinal Degeneration

M. Danciger; D. Ogando; H. Yang; K. C. Ahern; N. Akhmedov; J. S. Friedman; A. Swaroop; R. W. Williams; D. B. Farber; M. M. LaVail

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):6081. doi:

ARVO Annual Meeting Abstract May 2008

Genetic Modifiers of Age-Related Photoreceptor Degeneration/Maintenance

D. G. Ogando; H. Yang; M. T. Matthes; M. Alizadeh; J. Z. Li; N. Yu; B. Rohrer; D. Vollrath; M. M. LaVail; M. Danciger

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):6082. doi:

ARVO Annual Meeting Abstract May 2007

Discovery of QTL That Modify rd3-Induced Retinal Degeneration in the Mouse Model; Several Are in Common With QTL Affecting Age-Related Retinal Degeneration

M. Danciger; H. Yang; R. Ralston; Y. Liu; M. T. Matthes; D. Yasumura; M. M. LaVail

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):4633. doi:

ARVO Annual Meeting Abstract May 2006

The C57BL/6–c2J Albino Background Reduces the Severity of Light–Sensitive rd3 Disease but Not by Means of the RPE65 Met450 Variant

M. Danciger; L. Handschumacher; D. Yasumura; M.T. Matthes; M.M. LaVail; H. Yang

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):3257. doi:

Biochemistry and Molecular Biology April 2006

Disruption of the Gene Encoding the β1-Subunit of Transducin in the Rd4 /+ Mouse

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Eiko Kitamura; Michael Danciger; Clyde Yamashita; Nagesh P. Rao; Steven Nusinowitz; Bo Chang; Debora B. Farber
TAGS: bacterial artificial chromosomes, genes, mice, rna, messenger, transducin, proteins, chromosomes, mice, inbred c57bl
Invest. Ophthalmol. Vis. Sci.. 2006; 47(4):1293-1301. doi: https://doi.org/10.1167/iovs.05-1164

ARVO Annual Meeting Abstract May 2005

The C57BL/6 Background Protects Against rd3 Retinal Degeneration

M. Danciger; L. Handschumacher; M.M. LaVail; S. Nusinowitz; H. Yang

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):3177. doi:

ARVO Annual Meeting Abstract May 2005

A Quantitative Genetics Study of Age–Related Retinal Degeneration Between the A/J and C57BL/6 Mouse Strains

H. Yang; L. Handschumacher; M.M. LaVail; M. Danciger

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):3819. doi:

ARVO Annual Meeting Abstract May 2004

A quantitative genetics retinal light damage study of a cross between one resistant and one sensitive albino mouse strain each with the RPE65–MET450 variant shows no QTL at the Rpe65 locus.

M. Danciger; D. Worrill; J. Lyon; T. Hill; H. Yang; M.M. LaVail

Invest. Ophthalmol. Vis. Sci.. 2004; 45(13):3716. doi:

ARVO Annual Meeting Abstract May 2004

A new locus for autosomal recessive Retinitis Pigmentosa (arRP) on chromosome 3p26–25.

M.D. Mohamed; A. Jackson; G. Williams; M. Danciger; J. Keen; C.F. Inglehearn

Invest. Ophthalmol. Vis. Sci.. 2004; 45(13):4746. doi:

Biochemistry and Molecular Biology June 2003

A Strong and Highly Significant QTL on Chromosome 6 that Protects the Mouse from Age-Related Retinal Degeneration

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Michael Danciger; Jessica Lyon; Danielle Worrill; Matthew M. LaVail; Haidong Yang
TAGS: mice, quantitative trait loci, retinal degeneration, chromosomes, human, pair 6, alleles
Invest. Ophthalmol. Vis. Sci.. 2003; 44(6):2442-2449. doi: https://doi.org/10.1167/iovs.02-1252

ARVO Annual Meeting Abstract May 2003

Highly Significant QTLs on Mouse Chromosomes 6, 10 and 16 that Strongly Influence Age-related Retinal Degeneration; Comparison with Light Damage QTLs

M. Danciger; H. Yang; J.E. Lyon; D.M. Worrill; M.M. LaVail

Invest. Ophthalmol. Vis. Sci.. 2003; 44(13):2021. doi:

ARVO Annual Meeting Abstract May 2003

A Variant in the 5'UTR of the Cone Gene Encoding the Cone Gamma Subunit of cGMP-PDE that Causes Overexpression of the Protein; Disease-causing Mutation or Rare Polymorphism?

N.I. Piriev; Y. Gao; E. Mendoza; G.A. Fishman; M. Danciger; D.B. Farber

Invest. Ophthalmol. Vis. Sci.. 2003; 44(13):3530. doi:

ARVO Annual Meeting Abstract May 2003

Highly Significant QTLs on Mouse Chrs 4 and 6 that Influence Light-induced Retinal Degeneration; Comparison with Age-related Retinal Degeneration QTLs

C. Grimm; A. Wenzel; C.E. Remé; J. Lem; J.E. Lyon; D.M. Worrill; M. Danciger

Invest. Ophthalmol. Vis. Sci.. 2003; 44(13):3565. doi:

ARVO Annual Meeting Abstract December 2002

Electrophysiological Evidence for Slower Photoreceptor Recovery in Albino Mice with the MET450 Variant in the Rpe65 Gene

S Nusinowitz; LT Nguyen; DB Farber; M Danciger

Invest. Ophthalmol. Vis. Sci.. 2002; 43(13):3758. doi:

Biochemistry and Molecular Biology October 2001

CORD9 a New Locus for arCRD: Mapping to 8p11, Estimation of Frequency, Evaluation of a Candidate Gene

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Michael Danciger; Jaimie Hendrickson; Jessica Lyon; Carmel Toomes; John C. McHale; Gerald A. Fishman; Chris F. Inglehearn; Samuel G. Jacobson; Debora B. Farber
TAGS: candidate disease gene, family, genotype determination, genes, mutation
Invest. Ophthalmol. Vis. Sci.. 2001; 42(11):2458-2465. doi:

Retina June 2000

Disease Expression of RP1 Mutations Causing Autosomal Dominant Retinitis Pigmentosa

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Samuel G. Jacobson; Artur V. Cideciyan; Alessandro Iannaccone; Richard G. Weleber; Gerald A. Fishman; Albert M. Maguire; Louisa M. Affatigato; Jean Bennett; Eric A. Pierce; Michael Danciger; Debora B. Farber; Edwin M. Stone
TAGS: mutation, retinitis pigmentosa, retinal cone, rod photoreceptors, phenotype, family, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2000; 41(7):1898-1908. doi:

Biochemistry and Molecular Biology July 1999

Screening of the Gene Encoding the α′-Subunit of Cone cGMP-PDE in Patients with Retinal Degenerations

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Yong Qing Gao; Michael Danciger; Reid Longmuir; Natik I. Piriev; Dan Yun Zhao; John R. Heckenlively; Gerald A. Fishman; Richard G. Weleber; Samuel G. Jacobson; Edwin M. Stone; Debora B. Farber
TAGS: cyclic gmp, exons, genes, retinal cone, retinal degeneration, screening, polymorphism, single-stranded conformational
Invest. Ophthalmol. Vis. Sci.. 1999; 40(8):1818-1822. doi:

Articles August 1990

Fine mapping of a putative rd cDNA and its co-segregation with rd expression.

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M Danciger; C Bowes; C A Kozak; M M LaVail; D B Farber
TAGS: dna, complementary
Invest. Ophthalmol. Vis. Sci.. 1990; 31(8):1427-1432. doi:

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Influence of a Quantitative Trait Locus on Mouse Chromosome 19 to the Light-Adapted Electroretinogram

Genetic Modifiers of Retinal Degeneration in the rd3 Mouse

Genetic Modifiers of rd3 Retinal Degeneration

Genetic Modifiers of Age-Related Photoreceptor Degeneration/Maintenance

Discovery of QTL That Modify rd3-Induced Retinal Degeneration in the Mouse Model; Several Are in Common With QTL Affecting Age-Related Retinal Degeneration

The C57BL/6–c2J Albino Background Reduces the Severity of Light–Sensitive rd3 Disease but Not by Means of the RPE65 Met450 Variant

Disruption of the Gene Encoding the β1-Subunit of Transducin in the Rd4 /+ Mouse

The C57BL/6 Background Protects Against rd3 Retinal Degeneration

A Quantitative Genetics Study of Age–Related Retinal Degeneration Between the A/J and C57BL/6 Mouse Strains

A quantitative genetics retinal light damage study of a cross between one resistant and one sensitive albino mouse strain each with the RPE65–MET450 variant shows no QTL at the Rpe65 locus.

A new locus for autosomal recessive Retinitis Pigmentosa (arRP) on chromosome 3p26–25.

A Strong and Highly Significant QTL on Chromosome 6 that Protects the Mouse from Age-Related Retinal Degeneration

Highly Significant QTLs on Mouse Chromosomes 6, 10 and 16 that Strongly Influence Age-related Retinal Degeneration; Comparison with Light Damage QTLs

A Variant in the 5'UTR of the Cone Gene Encoding the Cone Gamma Subunit of cGMP-PDE that Causes Overexpression of the Protein; Disease-causing Mutation or Rare Polymorphism?

Highly Significant QTLs on Mouse Chrs 4 and 6 that Influence Light-induced Retinal Degeneration; Comparison with Age-related Retinal Degeneration QTLs

Electrophysiological Evidence for Slower Photoreceptor Recovery in Albino Mice with the MET450 Variant in the Rpe65 Gene

CORD9 a New Locus for arCRD: Mapping to 8p11, Estimation of Frequency, Evaluation of a Candidate Gene

Disease Expression of RP1 Mutations Causing Autosomal Dominant Retinitis Pigmentosa

Screening of the Gene Encoding the α′-Subunit of Cone cGMP-PDE in Patients with Retinal Degenerations

Fine mapping of a putative rd cDNA and its co-segregation with rd expression.

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