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Physiology and Pharmacology May 2020

Small Molecules Restore Bestrophin 1 Expression and Function of Both Dominant and Recessive Bestrophinopathies in Patient-Derived Retinal Pigment Epithelium

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Jingshu Liu; Rachel L. Taylor; Richard A. Baines; Lisa Swanton; Sally Freeman; Barbara Corneo; Achchhe Patel; Alan Marmorstein; Travis Knudsen; Graeme C. Black; Forbes Manson
TAGS: best1 gene, molecule, bestrophinopathy, small molecule, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):28. doi: https://doi.org/10.1167/iovs.61.5.28

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Small molecules restore the expression and function of mutant alleles underpinning autosomal dominant and recessive inherited retinal dystrophies

Jingshu Liu; Forbes Manson; Graeme Black

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6056. doi:

Retina May 2017

Associations Between β-Peripapillary Atrophy and Reticular Pseudodrusen in Early Age-Related Macular Degeneration

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Aakriti Garg; Dana M. Blumberg; Lama A. Al-Aswad; Maris Oll; Suzanne Yzer; Max Forbes; Rando L. Allikmets; Srilaxmi Bearelly
TAGS: age-related macular degeneration, atrophy, glaucoma, eye, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2810-2815. doi: https://doi.org/10.1167/iovs.16-20343

ARVO Annual Meeting Abstract September 2016

Functional expression of Bestrophin-1 in vitro following transduction with viral vectors.

Shaun Roger Wood; Michelle McClements; Maria Ines Patricio; Robert E MacLaren; Carolina Uggenti; Sumathi Sekaran; Forbes D Manson

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1174. doi:

ARVO Annual Meeting Abstract June 2015

PROGRESS TOWARDS GENERATING ZEBRAFISH MODELS OF RETINITIS PIGMENTOSA

Hannah Elizabeth Henson; Marie Ann Forbes-Osborne; Sara N Perkins; Ann C Morris; Retinal Cell Biology

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5389. doi:

ARVO Annual Meeting Abstract April 2014

Use of small molecules to correct mutant bestrophin-1 localization.

Carolina Uggenti; Lisa Swanton; Forbes D Manson

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6015. doi:

ARVO Annual Meeting Abstract April 2014

Development of allele specific gene silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I

David G Courtney; Sarah D Atkinson; Johnny E Moore; Eleonora Maurizi; Graziella Pellegrini; Graeme C Black; Forbes D Manson; Gary Hin-Fai Yam; Irwin W McLean; Tara C B Moore

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4069. doi:

Cornea February 2014

Development of Allele-Specific Gene-Silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I

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David G. Courtney; Sarah D. Atkinson; Johnny E. Moore; Eleonora Maurizi; Chiara Serafini; Graziella Pellegrini; Graeme C. Black; Forbes D. Manson; Gary H. F. Yam; Caroline J. MacEwen; Edwin H. A. Allen; W. H. Irwin McLean; C. B. Tara Moore
TAGS: alleles, corneal epithelial cells, gene silencing, meretoja syndrome, pyrosequencing, rna, small interfering, proteins, luciferases, mutation, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2014; 55(2):977-985. doi: https://doi.org/10.1167/iovs.13-13279

ARVO Annual Meeting Abstract June 2013

The transcription factor Insm1 regulates photoreceptor differentiation and cell cycle progression

Marie Forbes-Osborne; Stephen Wilson; Ann Morris

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3752. doi:

ARVO Annual Meeting Abstract June 2013

Transcriptional regulation by Her proteins during vertebrate retinal development

Stephen Wilson; Marie Forbes-Osborne; Ann Morris

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3754. doi:

Retina August 2012

RPGR- Associated Retinal Degeneration in Human X-Linked RP and a Murine Model

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Wei Chieh Huang; Alan F. Wright; Alejandro J. Roman; Artur V. Cideciyan; Forbes D. Manson; Dina Y. Gewaily; Sharon B. Schwartz; Sam Sadigh; Maria P. Limberis; Peter Bell; James M. Wilson; Anand Swaroop; Samuel G. Jacobson
TAGS: mice, retinal cone, retinal degeneration, retinal diseases, rod photoreceptors, x-linked inheritance, electroretinography, retina, histopathology tests, phenotype
Invest. Ophthalmol. Vis. Sci.. 2012; 53(9):5594-5608. doi: https://doi.org/10.1167/iovs.12-10070

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Assessment of Anterior Segment Anatomy Using Anterior Segment Optical Coherence Tomography and Ultrasound Biomicroscopy Following Argon Laser Peripheral Iridoplasty

Brian J. Song; Max Forbes; Dana Blumberg; Ronald H. Silverman

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1996. doi:

ARVO Annual Meeting Abstract April 2011

Investigating The Role Of Insm1a In Photoreceptor Development

Ann C. Morris; Marie A. Forbes-Osborne

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5424. doi:

Retinal Cell Biology April 2011

Microarray Analysis of XOPS-mCFP Zebrafish Retina Identifies Genes Associated with Rod Photoreceptor Degeneration and Regeneration

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Ann C. Morris; Marie A. Forbes-Osborne; Lakshmi S. Pillai; James M. Fadool
TAGS: genes, retina, rod photoreceptors, tissue degeneration, zebrafish, in situ hybridization, adult
Invest. Ophthalmol. Vis. Sci.. 2011; 52(5):2255-2266. doi: https://doi.org/10.1167/iovs.10-6022

Includes: Supplemental Content

ARVO Annual Meeting Abstract May 2008

Erythropoietin Receptor Plays a Role in the Cell Differentiation of Retina and Lens During Eye Development

L. Wu; S. Chang; Y. Chen; Q. Xia; M. Forbes; J. C. Tsai

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):3078. doi:

ARVO Annual Meeting Abstract May 2008

Ocular Safety of Serial Intravitreal Injections of Recombinant Human Erythropoietin: A 7 Month Study in Rabbits

B. J. Song; H. Cai; N. Gomes; S. Chang; J. C. Tsai; M. Forbes; L. V. Del Priore

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):5605. doi:

ARVO Annual Meeting Abstract May 2007

Intravitreal Injection of Recombinant Human Erythropoietin: A Study of Retinal Toxicity Using Electroretinography and Fluorescein Angiography in Rabbits

B. J. Song; H. Cai; S. Chang; J. C. Tsai; M. Forbes; L. V. Del Priore

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):251. doi:

ARVO Annual Meeting Abstract May 2007

Correlation of the Controlled Adverse Environment (CAE) Model With a Murine Model of Experimental Dry Eye in Assessing the Ability of Topical Doxycycline to Prevent Corneal Barrier Disruption

J. Crampton; M. B. Abelson; G. W. Ousler, III; S. Pflugfelder; C. De Paiva; M. Forbes; D. Power

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):402. doi:

ARVO Annual Meeting Abstract May 2007

Exogenous Erythropoietin Increased Retinal Superficial Vascular Density in Episcleral Venous Ligation Model of Aging Rats

L. Wu; S. Park; J. Cao; S. Chang; M. Forbes; J. C. Tsai

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):5683. doi:

ARVO Annual Meeting Abstract May 2006

Retinal Function Assessment Following Intravitreal Injection of Erythropoietin in Rats: A Dose–Toxicity Study

D. Hwang; S. Tari; L. Wu; S. Chang; M. Forbes; J.C. Tsai

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):5724. doi:

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Small Molecules Restore Bestrophin 1 Expression and Function of Both Dominant and Recessive Bestrophinopathies in Patient-Derived Retinal Pigment Epithelium

Small molecules restore the expression and function of mutant alleles underpinning autosomal dominant and recessive inherited retinal dystrophies

Associations Between β-Peripapillary Atrophy and Reticular Pseudodrusen in Early Age-Related Macular Degeneration

Functional expression of Bestrophin-1 in vitro following transduction with viral vectors.

PROGRESS TOWARDS GENERATING ZEBRAFISH MODELS OF RETINITIS PIGMENTOSA

Use of small molecules to correct mutant bestrophin-1 localization.

Development of allele specific gene silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I

Development of Allele-Specific Gene-Silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I

The transcription factor Insm1 regulates photoreceptor differentiation and cell cycle progression

Transcriptional regulation by Her proteins during vertebrate retinal development

RPGR- Associated Retinal Degeneration in Human X-Linked RP and a Murine Model

Assessment of Anterior Segment Anatomy Using Anterior Segment Optical Coherence Tomography and Ultrasound Biomicroscopy Following Argon Laser Peripheral Iridoplasty

Investigating The Role Of Insm1a In Photoreceptor Development

Microarray Analysis of XOPS-mCFP Zebrafish Retina Identifies Genes Associated with Rod Photoreceptor Degeneration and Regeneration

Erythropoietin Receptor Plays a Role in the Cell Differentiation of Retina and Lens During Eye Development

Ocular Safety of Serial Intravitreal Injections of Recombinant Human Erythropoietin: A 7 Month Study in Rabbits

Intravitreal Injection of Recombinant Human Erythropoietin: A Study of Retinal Toxicity Using Electroretinography and Fluorescein Angiography in Rabbits

Correlation of the Controlled Adverse Environment (CAE) Model With a Murine Model of Experimental Dry Eye in Assessing the Ability of Topical Doxycycline to Prevent Corneal Barrier Disruption

Exogenous Erythropoietin Increased Retinal Superficial Vascular Density in Episcleral Venous Ligation Model of Aging Rats

Retinal Function Assessment Following Intravitreal Injection of Erythropoietin in Rats: A Dose–Toxicity Study

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