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ARVO Annual Meeting Abstract June 2022

A 6-Month GLP Toxicology Study of a Novel Hydrogel-based, Axitinib Intravitreal Implant (OTX-TKI) in Non-Human Primates

Chintan Patel; Erica Kahn; Megan Priem; Joe Iacona; Andrew Vanslette; Erik Wong; Charles D Blizzard; Peter K Jarrett; Michael Goldstein; Rabia Gurses-Ozden

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):298 – F0101. doi:

ARVO Annual Meeting Abstract June 2022

A Safety and Pharmacokinetic Study of a Novel Hydrogel-based Axitinib Intravitreal Implant (OTX-TKI) in Non-Human Primates

Erica Kahn; Chintan Patel; Megan Priem; Joe Iacona; Andrew Vanslette; Erik Wong; Charles D Blizzard; Peter K Jarrett; Michael Goldstein; Rabia Gurses-Ozden

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):297 – F0100. doi:

ARVO Annual Meeting Abstract June 2022

Safety and Pharmacodynamic Assessment of Repeated Intracameral Travoprost Implant Administration in Beagle Dogs

Charles D Blizzard; Chintan Patel; Jeremy Hartman; Sean Serell; Kevin Yeh; Andrew Vanslette; Peter K Jarrett; Michael Goldstein; Rabia Gurses-Ozden

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2852 – A0375. doi:

ARVO Annual Meeting Abstract June 2022

Pharmacokinetics of a Hydrogel-based Nepafenac Intracanalicular Insert in Canines

Oktay Uzun; Ankita Desai; Sanjani Ray; Chintan Patel; Charles D Blizzard; Peter K Jarrett; Michael Goldstein

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):447. doi:

ARVO Annual Meeting Abstract June 2022

Efficacy and Safety of OTX-DED Dexamethasone Intracanalicular Insert in Subjects with Dry Eye Disease: A Multicenter, Randomized, Vehicle-Controlled Phase 2 Study

Lisa Nijm; Joseph Tauber; David G. Evans; Betsy Gillick; Rabia Gurses-Ozden; Michael Goldstein

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1558 – A0283. doi:

ARVO Annual Meeting Abstract June 2022

Pharmacokinetics of a Hydrogel-based Besifloxacin Intracanalicular Insert in Canines

Megan Priem; Ankita Desai; Chintan Patel; Charles D Blizzard; Peter K Jarrett; Michael Goldstein

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2128 – F0144. doi:

ARVO Annual Meeting Abstract June 2021

Fully Integrated Home OCT System – A Longitudinal Pilot StudyFully Integrated Home OCT System – A Longitudinal Pilot Study

Michaella Goldstein; Dafna Goldberg; Dinah Zur; Shiri Shulman; Anat Loewenstein; Tiarnan D L Keenan

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1895. doi:

ARVO Annual Meeting Abstract June 2021

Incidence of Endophthalmitis Following Routine or Complex Cataract Surgery in Practices With and Without Access to Hydrogel Sealant: Retrospective Study Using the IRIS Registry

Michael Goldstein; Jamie L Metzinger; Helene Fevrier; Srilatha Vantipalli; Nicole Oliynyk; Andrew A Moshfeghi

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1726. doi:

ARVO Annual Meeting Abstract June 2021

Artificial intelligence algorithm for retinal fluid volume quantification from self-imaging with a Home OCT System

Anat Loewenstein; Dafna Goldberg; Dinah Zur; Shiri Shulman; Tiarnan D L Keenan; Michaella Goldstein

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):351. doi:

ARVO Annual Meeting Abstract June 2021

Pharmacokinetics of OTX-CSI, a Cyclosporine Intracanalicular Insert, in Surgically Induced Dry Eye Beagle Dogs

Andrew Vanslette; Charles D Blizzard; Art Driscoll; Matthew Cheung; Michael H Goldstein

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):736. doi:

ARVO Annual Meeting Abstract June 2021

Ocular Pharmacokinetics of OTX-DED, a Sustained-release Intracanalicular Insert Delivering Dexamethasone, in a Canine Model

Charles D Blizzard; Ankita Desai; Art Driscoll; Matthew Cheung; Michael H Goldstein

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1323. doi:

ARVO Annual Meeting Abstract June 2021

Safety of an Intracanalicular Dexamethasone Insert for the Treatment of Allergic Conjunctivitis: Pooled Post-hoc Analysis of Four Studies

John Meyer; Kenneth Kenyon; Michelle Sato; Steven M Silverstein; Edward J Meier; Karen Dewar; Erin Reilly; Paul J Gomes; Matthew Cheung; Michael H Goldstein

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):731. doi:

ARVO Annual Meeting Abstract June 2021

Phase 1 Study of an Intracameral Travoprost Hydrogel-based Implant for the Treatment of POAG and Ocular Hypertension

Damien Goldberg; Thomas Walters; Jason Bacharach; Matthew Cheung; Elizabeth Braun; Dabiana Silva; Michael H Goldstein

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2765. doi:

ARVO Annual Meeting Abstract June 2021

Phase 1 Study of an Intravitreal Axitinib Hydrogel-based Implant for the Treatment of Neovascular Age-Related Macular Degeneration (nAMD)

James Gilbert Wong; Andrew Chang; Robyn H Guymer; Sanjeewa Wickremasinghe; Erin Reilly; Nicki Bell; Srilatha Vantipalli; Andrew A Moshfeghi; Michael H Goldstein

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):218. doi:

ARVO Annual Meeting Abstract June 2020

Evaluation of the Safety and Efficacy of OTX-TP, an intracanalicular travoprost insert, for the treatment of patients with open-angle glaucoma or ocular hypertension: A Phase 3 Study

Srilatha Vantipalli; Kenneth N Sall; Emil Stein; Howard Schenker; Jay Mulaney; Robert Smyth-Medina; Douglas Day; Robert Benza; El-Roy Dixon; Nicole Rissman; Jamie Lynne Metzinger; Michael H Goldstein

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3488. doi:

ARVO Annual Meeting Abstract June 2020

Effect of Hydrogel Persistence on Pharmacodynamics and Tolerability of OTX-TIC, Travoprost Intracameral Implant in Beagles

Jennifer Langh; Charles D Blizzard; Arthur Driscoll; Ankita Desai; Noah Buff; Celia Johnston; Jeremy Hartman; Jessica Mangano; Nicholas Bova; Srilatha Vantipalli; Jamie Lynne Metzinger; Michael H Goldstein

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1242. doi:

ARVO Annual Meeting Abstract June 2020

Evaluating Safety and Pharmacokinetics of OTX-CSI, a Sustained Release Intracanalicular Cyclosporine Insert in Beagles

Andrew Vanslette; Paul Haberman; Charles D Blizzard; Arthur Driscoll; Srilatha Vantipalli; Jamie Lynne Metzinger; Michael H Goldstein

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3258. doi:

ARVO Annual Meeting Abstract June 2020

Evaluating Tolerability and Pharmacokinetics of OTX-BDI, a Sustained-Release Intracanalicular Insert Co-Delivering Besifloxacin & Dexamethasone in Beagles

Courtney Rosales; Charles D Blizzard; Tyler Peters; Luke Rausch; Arthur Driscoll; Srilatha Vantipalli; Jamie Lynne Metzinger; Michael H Goldstein

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):426. doi:

ARVO Annual Meeting Abstract June 2020

Evaluating Safety, Tolerability and Efficacy of an Intracameral Hydrogel-Based Travoprost Implant in Subjects with Glaucoma - Phase 1 Trial

Michael H Goldstein; Damien Goldberg; Thomas Richard Walters; Srilatha Vantipalli; Elizabeth Braun; Jamie Lynne Metzinger

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4266. doi:

ARVO Annual Meeting Abstract July 2019

A 12-month Prospective Study to Evaluate the Efficacy of Treat and Extend Regimen (T&E) of Intravitreal Aflibercept as a Second-Line Treatment for Diabetic Macular Edema (TADI Study)

Tareq Ziad Jaouni; Rita Ehrlich; Yoreh Barak; Haia Katz; Russell Pokroy; Jaime Levy; Joel Hanhart; Ori Segal; Shiri Shulman; Michaella Goldstein; Liran Tiossano; Itay Chowers

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3641. doi:

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A 6-Month GLP Toxicology Study of a Novel Hydrogel-based, Axitinib Intravitreal Implant (OTX-TKI) in Non-Human Primates

A Safety and Pharmacokinetic Study of a Novel Hydrogel-based Axitinib Intravitreal Implant (OTX-TKI) in Non-Human Primates

Safety and Pharmacodynamic Assessment of Repeated Intracameral Travoprost Implant Administration in Beagle Dogs

Pharmacokinetics of a Hydrogel-based Nepafenac Intracanalicular Insert in Canines

Efficacy and Safety of OTX-DED Dexamethasone Intracanalicular Insert in Subjects with Dry Eye Disease: A Multicenter, Randomized, Vehicle-Controlled Phase 2 Study

Pharmacokinetics of a Hydrogel-based Besifloxacin Intracanalicular Insert in Canines

Fully Integrated Home OCT System – A Longitudinal Pilot StudyFully Integrated Home OCT System – A Longitudinal Pilot Study

Incidence of Endophthalmitis Following Routine or Complex Cataract Surgery in Practices With and Without Access to Hydrogel Sealant: Retrospective Study Using the IRIS Registry

Artificial intelligence algorithm for retinal fluid volume quantification from self-imaging with a Home OCT System

Pharmacokinetics of OTX-CSI, a Cyclosporine Intracanalicular Insert, in Surgically Induced Dry Eye Beagle Dogs

Ocular Pharmacokinetics of OTX-DED, a Sustained-release Intracanalicular Insert Delivering Dexamethasone, in a Canine Model

Safety of an Intracanalicular Dexamethasone Insert for the Treatment of Allergic Conjunctivitis: Pooled Post-hoc Analysis of Four Studies

Phase 1 Study of an Intracameral Travoprost Hydrogel-based Implant for the Treatment of POAG and Ocular Hypertension

Phase 1 Study of an Intravitreal Axitinib Hydrogel-based Implant for the Treatment of Neovascular Age-Related Macular Degeneration (nAMD)

Evaluation of the Safety and Efficacy of OTX-TP, an intracanalicular travoprost insert, for the treatment of patients with open-angle glaucoma or ocular hypertension: A Phase 3 Study

Effect of Hydrogel Persistence on Pharmacodynamics and Tolerability of OTX-TIC, Travoprost Intracameral Implant in Beagles

Evaluating Safety and Pharmacokinetics of OTX-CSI, a Sustained Release Intracanalicular Cyclosporine Insert in Beagles

Evaluating Tolerability and Pharmacokinetics of OTX-BDI, a Sustained-Release Intracanalicular Insert Co-Delivering Besifloxacin & Dexamethasone in Beagles

Evaluating Safety, Tolerability and Efficacy of an Intracameral Hydrogel-Based Travoprost Implant in Subjects with Glaucoma - Phase 1 Trial

A 12-month Prospective Study to Evaluate the Efficacy of Treat and Extend Regimen (T&E) of Intravitreal Aflibercept as a Second-Line Treatment for Diabetic Macular Edema (TADI Study)

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