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ARVO Annual Meeting Abstract June 2020

Integrative Prioritization of IOP-associated Genes Using High Throughput Genomic Data

Yutao Liu; Emily Parker; Hannah Youngblood; Jingwen Cai; Kristin Marie Perkumas; Janey Wiggs; Louis R Pasquale; Michael A Hauser; Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):990. doi:

ARVO Annual Meeting Abstract June 2020

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

Janey Wiggs; Puya Gharahkhani; Eric Jorgenson; Pirro G Hysi; Anthony Khawaja; Sarah Pendergrass; Xikun Han; David Mackey; Christopher Hammond; Michael A Hauser; Louis R Pasquale; Caroline Klaver; Michiaki Kubo; Tin Aung; Jamie E Craig; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1890. doi:

ARVO Annual Meeting Abstract June 2020

LOXL1-AS1 regulates extracellular matrix remodeling and mechanotransduction in human primary trabecular meshwork and Schlemm’s canal cells

Heather Schmitt; William M. Johnson; Maria Gomez-Caraballo; Kristin Marie Perkumas; Michael A Hauser; Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4629. doi:

ARVO Annual Meeting Abstract July 2019

The PEXpress lncRNA/hnRNPL complex regulates signaling and morphology of human Schlemm’s canal cells

Heather Schmitt; William Johnson; Shelby Strickland; Michael A Hauser; William D Stamer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3185. doi:

ARVO Annual Meeting Abstract July 2019

Abnormal Extracellular Matrix Homeostasis of Trabecular Meshwork Cells Isolated from Human Donor Eyes with Pseudoexfoliation Syndrome

Katy C Liu; Raghunathan VijayKrishna; Iris D Navarro; Michael A Hauser; W Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3186. doi:

ARVO Annual Meeting Abstract July 2019

Role of LOXL1 in conventional outflow function and behavior

Guorong Li; William M Johnson; Heather Schmitt; Iris D Navarro; Jenny Jingyi Cui; Marybeth Groelle; Haven Roberts; Michael A Hauser; William D Stamer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3190. doi:

ARVO Annual Meeting Abstract July 2018

Homozygous Mutation in the ELMO3 Gene with Keratoconus

Mariam Lotfy Khaled; Khaled Abu-Amero; Abdulrahman Al-Muammar; Yelena Bykhovskaya; Xiaoyo Gao; Michael A Hauser; R. Rand Allingham; Yaron Rabinowitz; Yutao Liu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):743. doi:

ARVO Annual Meeting Abstract July 2018

Association of APBB2 Links Mechanisms of Neurodegeneration in Glaucoma and Alzheimer's Disease

Michael A Hauser

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1183. doi:

ARVO Annual Meeting Abstract July 2018

Long Non-Coding RNAs in Keratoconus-affected Human Cornea

Yutao Liu; Mariam Lotfy Khaled; Yelena Bykhovskaya; Hanzhou Li; W Daniel Stamer; Hongyan Xu; R. Rand Allingham; Michael A Hauser; Yaron Rabinowitz

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4391. doi:

ARVO Annual Meeting Abstract July 2018

Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations.

Pieter W.M. Bonnemaijer; Adriana I Iglesias; Anna Sanyiwa; Hassan G Hassan; Heiko Philippin; Colin Cook; Janey L Wiggs; Christopher J Hammond; Michael A Hauser; Hans G Lemij; Ruth Loos; Cornelia van Duijn; Alberta A H J Thiadens; Caroline C W Klaver

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5136. doi:

Cornea June 2018

Differential Expression of Coding and Long Noncoding RNAs in Keratoconus-Affected Corneas

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Mariam Lofty Khaled; Yelena Bykhovskaya; Sarah E. R. Yablonski; Hanzhou Li; Michelle D. Drewry; Inas F. Aboobakar; Amy Estes; X. Raymond Gao; W. Daniel Stamer; Hongyan Xu; R. Rand Allingham; Michael A. Hauser; Yaron S. Rabinowitz; Yutao Liu
TAGS: cornea, keratoconus, rna, genes
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2717-2728. doi: https://doi.org/10.1167/iovs.18-24267

Includes: Supplemental Content

Glaucoma February 2018

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

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Jessica N. Cooke Bailey; Puya Gharahkhani; Jae H. Kang; Mariusz Butkiewicz; David A. Sullivan; Robert N. Weinreb; Hugues Aschard; R. Rand Allingham; Allison Ashley-Koch; Richard K. Lee; Sayoko E. Moroi; Murray H. Brilliant; Gadi Wollstein; Joel S. Schuman; John H. Fingert; Donald L. Budenz; Tony Realini; Terry Gaasterland; William K. Scott; Kuldev Singh; Arthur J. Sit; Robert P. Igo, Jr; Yeunjoo E. Song; Lisa Hark; Robert Ritch; Douglas J. Rhee; Douglas Vollrath; Donald J. Zack; Felipe Medeiros; Thasarat S. Vajaranant; Daniel I. Chasman; William G. Christen; Margaret A. Pericak-Vance; Yutao Liu; Peter Kraft; Julia E. Richards; Bernard A. Rosner; Michael A. Hauser; Jamie E. Craig; Kathryn P. Burdon; Alex W. Hewitt; David A. Mackey; Jonathan L. Haines; Stuart MacGregor; Janey L. Wiggs; Louis R. Pasquale; for the Australian and New Zealand Registry of Advanced Glaucoma (ANZRAG) Consortium
TAGS: testosterone, metabolism, polymorphism, glaucoma, genes, open-angle glaucoma, datasets
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):629-636. doi: https://doi.org/10.1167/iovs.17-22708

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Differential miRNA Expression in Response to Mechanical Stress in Human Trabecular Meshwork Cells

Inas Helwa; Michelle Drewry; William M Johnson; W. Michael Dismuke; Inas F Aboobakar; Kristin Marie Perkumas; R. Rand Allingham; Michael A Hauser; W. Daniel Stamer; Yutao Liu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3481. doi:

ARVO Annual Meeting Abstract June 2017

Differential Expression of Coding and Long Noncoding RNAs in Keratoconic Corneas

Yutao Liu; Yelena Bykhovskaya; Mariam L Khaled; Michelle Drewry; Inas F Aboobakar; Amy Estes; Xiaoyi Gao; R Rand Allingham; Michael A Hauser; Yaron S. Rabinowitz

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5560. doi:

ARVO Annual Meeting Abstract June 2017

Identification of the hnRNPL and LOXL1-AS1 lncRNA complex: Implications for pathology in exfoliation glaucoma

William Marshall Johnson; Inas F Aboobakar; Laura Finnegan; R Rand Allingham; Michael A Hauser; W Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5590. doi:

ARVO Annual Meeting Abstract June 2017

Knockdown of the lncRNA LOXL1-AS1 and the protein-coding gene LOXL1 alters expression of genes and pathways implicated in exfoliation syndrome pathogenesis

Inas F Aboobakar; David Corcoran; William Marshall Johnson; R Rand Allingham; W Daniel Stamer; Michael A Hauser

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5622. doi:

ARVO Annual Meeting Abstract September 2016

Genome-wide association study comparing patients with exfoliation syndrome and exfoliation glaucoma.

Mineo Ozaki; Francesca Pasutto; Takanori Mizoguchi; Michael A Hauser; Fotis Topouzis; Michael Dubina; Deepak P Edward; Ningli Wang; Tin Aung; Chiea Chuen Khor

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):788. doi:

ARVO Annual Meeting Abstract September 2016

A lncRNA in the LOXL1 locus modulates expression of genes relevant to exfoliation glaucoma pathobiology

Inas F Aboobakar; Xue Qin; W Daniel Stamer; R Rand Allingham; Michael A Hauser

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):790. doi:

ARVO Annual Meeting Abstract September 2016

miRNA-Seq in four different normal human ocular tissues

Michelle Dianne Drewry; Inas Helwa; R. Rand Allingham; Michael A Hauser; Yutao Liu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):794. doi:

ARVO Annual Meeting Abstract September 2016

DNA methylation in Human SC Cells with Glaucoma

Jingwen Cai; Michelle Dianne Drewry; Kristin Perkumas; Michael Dismuke; Iris Navarro; Michael A Hauser; W Daniel Stamer; Yutao Liu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):804. doi:

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Integrative Prioritization of IOP-associated Genes Using High Throughput Genomic Data

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

LOXL1-AS1 regulates extracellular matrix remodeling and mechanotransduction in human primary trabecular meshwork and Schlemm’s canal cells

The PEXpress lncRNA/hnRNPL complex regulates signaling and morphology of human Schlemm’s canal cells

Abnormal Extracellular Matrix Homeostasis of Trabecular Meshwork Cells Isolated from Human Donor Eyes with Pseudoexfoliation Syndrome

Role of LOXL1 in conventional outflow function and behavior

Homozygous Mutation in the ELMO3 Gene with Keratoconus

Association of APBB2 Links Mechanisms of Neurodegeneration in Glaucoma and Alzheimer's Disease

Long Non-Coding RNAs in Keratoconus-affected Human Cornea

Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations.

Differential Expression of Coding and Long Noncoding RNAs in Keratoconus-Affected Corneas

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

Differential miRNA Expression in Response to Mechanical Stress in Human Trabecular Meshwork Cells

Differential Expression of Coding and Long Noncoding RNAs in Keratoconic Corneas

Identification of the hnRNPL and LOXL1-AS1 lncRNA complex: Implications for pathology in exfoliation glaucoma

Knockdown of the lncRNA LOXL1-AS1 and the protein-coding gene LOXL1 alters expression of genes and pathways implicated in exfoliation syndrome pathogenesis

Genome-wide association study comparing patients with exfoliation syndrome and exfoliation glaucoma.

A lncRNA in the LOXL1 locus modulates expression of genes relevant to exfoliation glaucoma pathobiology

miRNA-Seq in four different normal human ocular tissues

DNA methylation in Human SC Cells with Glaucoma

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