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Cornea June 2025

Pyroptosis Mediated by ROS/Caspase-3/GSDME Pathway in Aspergillus fumigatus –Induced Fungal Keratitis

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Jingze Kan; Shiqi Song; Mengzhu Liu; Qiang Xu; Jieun Lee; Jintao Sun; Shasha Xue; Xiaoyan Sun; Chengye Che
TAGS: aspergillus fumigatus, caspase-3, cornea, fungal keratitis, infections, inflammation, keratitis, mice, pyroptosis, rna, small interfering
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):52. https://doi.org/10.1167/iovs.66.6.52

Cornea June 2025

HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway

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Hua Yang; Mengzhu Liu; Shiqi Song; Qiang Xu; Jieun Lee; Jintao Sun; Shasha Xue; Xiaoyan Sun; Chengye Che
TAGS: aspergillus fumigatus, caspase-8, cornea, inflammatory response, keratitis, macrophages, mice, pyroptosis, infections, proteins
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):32. https://doi.org/10.1167/iovs.66.6.32

Immunology and Microbiology June 2025

Alterations of the Enteric Virome in Vogt-Koyanagi-Harada Disease

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Mingzhu Liu; Jiawei Geng; Siyan Jin; Ping Hu; Xia Wang; Xiaoli Liu
TAGS: uveomeningoencephalitic syndrome, virome, viruses
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):15. https://doi.org/10.1167/iovs.66.6.15

Includes: Supplemental Content

Lens April 2025

Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development

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Dongzhe Zhang; Junwei Qu; Cuncun Ke; Xiumei Kong; Mengyun Liu; Iqbal Nawaz Khan; Shuxin Huang; Haijiao Tian; Tong Xie; Ke Qiu; Jing Li; Mingli Wang; Hui Li; Fengling Yuan; Weikai Guo; Mingya Cao; Jing Zhang; Keke Zhu; Jin Luo; Fengyan Zhang; Xiukun Cui; Hongmei Mu; Yanzhong Hu
TAGS: body tissue, cataract, epithelium, infections, lens (device), macrophages, risk factors, porphyromonas gingivalis, hypertension, lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):68. https://doi.org/10.1167/iovs.66.4.68

Includes: Supplemental Content

Retina March 2025

The Combination of Retinal Neurovascular Unit Changes With Carotid Artery Stenosis Enhances the Prediction of Ischemic Stroke

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Zhifan Chen; Shuoxin Liao; Guangzhong Chen; Changmao Li; Chunling Liu; Junbin Liu; Guangyu Wu; Zheng Lyu; Mengya Liu; Xiyu Wu; Guixian Ma; Qianli Meng
TAGS: carotid stenosis, ischemic stroke
Trans. Vis. Sci. Tech.. 2025; 14(3):14. https://doi.org/10.1167/tvst.14.3.14

Includes: Supplemental Content

Public Health February 2025

The Relationship Between Serum Biochemical Variables and Corneal Biomechanics Measured by Corvis ST Among Healthy Young Adults

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Dan-Lin Li; Min-Xin Liu; Ya-Jie Zheng; Yu Qin; Rong Ma; Gang Liang; Chen-Wei Pan
TAGS: biomechanics, cornea, young adult
Trans. Vis. Sci. Tech.. 2025; 14(2):19. https://doi.org/10.1167/tvst.14.2.19

Retina February 2025

Association Between Hormone Levels and Retinopathy in Patients With Type 2 Diabetes: A Cross-Sectional Study

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Yu Meng; Xueli Yang; Yuxin Fan; Ming Liu; Fengqi Zhou; Qihua Wang; Yuezhu Lu; Yun Zhu; Hua Yan
TAGS: diabetes mellitus, type 2, gonadal hormones, hormones, retinal diseases, testosterone
Trans. Vis. Sci. Tech.. 2025; 14(2):17. https://doi.org/10.1167/tvst.14.2.17

Includes: Supplemental Content

Genetics November 2024

Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort

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Mikko Liukkonen; Hanna Heloterä; Leea Siintamo; Bishwa Ghimire; Pirkko Mattila; Niko Kivinen; Joanna Kostanek; Cezary Watala; Maria Hytti; Juha Hyttinen; Ali Koskela; Janusz Blasiak; Kai Kaarniranta
TAGS: cohort studies, finnish, genes, inflammation, oxidative stress, rna, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):30. https://doi.org/10.1167/iovs.65.13.30

Includes: Supplemental Content

Visual Neuroscience November 2024

Overcoming Low mRNA Expression in White Matter: A Protocol for RNA Extraction From the Optic Nerve in Large Animals for Transcriptomic Analysis

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Zhonghao Yu; Yue Guan; Tian Xia; Xuanwen Li; Mingyue Liu; Yujia Huo; Zhuowei Wang; Zhirong Liu; Yuting Luo; Wentao Yan; Lanfang Sun; Wencan Wu; Baoguo Shen; Yikui Zhang
TAGS: optic nerve, rna, rna, messenger, white matter
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):25. https://doi.org/10.1167/iovs.65.13.25

Includes: Multimedia, Supplemental Content

Visual Neuroscience September 2024

Delayed Surgical Reversal of Optic Nerve Compression Leads to Exponential Degeneration of Optic Nerve Fibers and Selective Sparing of the Small Fibers

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XiaoHui Jiang; Boyue Xu; Shuang Yao; Zhuowei Wang; Mingyue Liu; Yikui Zhang; Wencan Wu; Ende Wu
TAGS: axon, decompression, external, decompressive incision, optic nerve, optic nerve compression, optic nerve decompression, surgical procedures, operative, tissue degeneration, survival, apoptosis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):40. https://doi.org/10.1167/iovs.65.11.40

ARVO Annual Meeting Abstract June 2024

Elevated IOP reduces lamina cribrosa oxygenation both directly through capillary distortion and indirectly by reducing perfusion from the posterior ciliary arteries

Yuankai Lu; Hasan Banna; Hua Yi; Hannah Schilpp; Mingna Liu; Fuqiang Zhong; Bingrui Wang; Andrew theophanous; Shaharoz Tahir; Po-Yi Lee; Joel R Palko; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):392.

ARVO Annual Meeting Abstract June 2024

An Explainable Artificial Intelligence System for Personalized Diabetic Retinopathy (DR) Screening: DR-PREDICT

Ting Fang Tan; Feihui Zheng; Gilbert Lim; Mingxuan Liu; Kabilan Elangovan; Nan Liu; Liyuan Jin; Daniel Ting

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3773.

ARVO Annual Meeting Abstract June 2024

Activation of limbal epithelial proliferation, is controlled, in part, by an ACE2/Lcn2 pathway

Han Peng; Huimin Jiang; Min Liu; Wending Yang; Elif Kayaalp Nalbant; Elwin D. Clutter; Nihal Kaplan; Robert M Lavker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):400.

ARVO Annual Meeting Abstract June 2024

Hyperreflective dots in Central Fovea visualized by visible-light Optical Coherence Tomography Fibergraphy

Marta Grannonico; Micheal Krause; David Andrew Miller; Weijia Fan; Mingna Liu; Roman Kuranov; Peter Netland; Xiaorong Liu; Hao F Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1436.

ARVO Annual Meeting Abstract June 2024

ON-EYE POSITIONING OF CORNEAL REFRACTIVE THERAPY TREATMENT ZONES

Grace Walther; Liandra Jung; Francisco Javier Gantes-Nuñez; Maria Liu; Pete S Kollbaum

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2700.

ARVO Annual Meeting Abstract June 2024

Investigation of Ophthalmic Drug Delivery through Topical Cream Eyelid Application using ex vivo Rabbit Eyes

Cailing Liu; Phillip Deardorff; Olivia Ferro; Yung Kuo; Inhou Chu; Victoria Wu; James Shiah; Michael Liu; Jason Hill

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3977.

ARVO Annual Meeting Abstract June 2024

Characterization of the ipRGC’s Role in Non-Image-Forming Pathways in Glaucoma

Wenjin Xu; Shichu Chang; Mingna Liu; Ignacio Provencio; Xiaorong Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4785.

ARVO Annual Meeting Abstract June 2024

Effect of Y-27632 on endoplasmic reticulum stress-induced human trabecular meshwork cells

Mengxuan Liu; Megumi Honjo; Reiko Yamagishi; Makoto Aihara

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5146.

ARVO Annual Meeting Abstract June 2024

Early Inflammatory Responses Following Acute Optic Nerve Injury in Mouse Vitreous and Retina

Shichu Chang; Wenjin Xu; Weijia Fan; Mingna Liu; Virginia Lee; Hao Zhang; Xiaorong Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6767.

ARVO Annual Meeting Abstract June 2024

Assessing the feasibility of using virtual reality to test binocular visual system

CHIEN MIAO LIU; ICHIAO YANG; Yayu Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3065.

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Pyroptosis Mediated by ROS/Caspase-3/GSDME Pathway in Aspergillus fumigatus –Induced Fungal Keratitis

HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway

Alterations of the Enteric Virome in Vogt-Koyanagi-Harada Disease

Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development

The Combination of Retinal Neurovascular Unit Changes With Carotid Artery Stenosis Enhances the Prediction of Ischemic Stroke

The Relationship Between Serum Biochemical Variables and Corneal Biomechanics Measured by Corvis ST Among Healthy Young Adults

Association Between Hormone Levels and Retinopathy in Patients With Type 2 Diabetes: A Cross-Sectional Study

Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort

Overcoming Low mRNA Expression in White Matter: A Protocol for RNA Extraction From the Optic Nerve in Large Animals for Transcriptomic Analysis

Delayed Surgical Reversal of Optic Nerve Compression Leads to Exponential Degeneration of Optic Nerve Fibers and Selective Sparing of the Small Fibers

Elevated IOP reduces lamina cribrosa oxygenation both directly through capillary distortion and indirectly by reducing perfusion from the posterior ciliary arteries

An Explainable Artificial Intelligence System for Personalized Diabetic Retinopathy (DR) Screening: DR-PREDICT

Activation of limbal epithelial proliferation, is controlled, in part, by an ACE2/Lcn2 pathway

Hyperreflective dots in Central Fovea visualized by visible-light Optical Coherence Tomography Fibergraphy

ON-EYE POSITIONING OF CORNEAL REFRACTIVE THERAPY TREATMENT ZONES

Investigation of Ophthalmic Drug Delivery through Topical Cream Eyelid Application using ex vivo Rabbit Eyes

Characterization of the ipRGC’s Role in Non-Image-Forming Pathways in Glaucoma

Effect of Y-27632 on endoplasmic reticulum stress-induced human trabecular meshwork cells

Early Inflammatory Responses Following Acute Optic Nerve Injury in Mouse Vitreous and Retina

Assessing the feasibility of using virtual reality to test binocular visual system

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