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Meeting Abstract (14)
Journal Articles (1)

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Investigative Ophthalmology & Visual Science (15)

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ARVO Annual Meeting Abstract (14)
Lens (1)

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Eye Anatomy and Disorders (1)
Genetics (1)
Lens (1)

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cataract (1)
cell death (1)
galactose (1)
glucose (1)
lens (device) (1)
lens epithelial cell (1)
lens, crystalline (1)
proteins (1)
rats (1)
stress (1)

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ARVO Annual Meeting Abstract April 2011

Age-Related Cataracts: Decrease in Nrf2/Keap1 Mediated Antioxidant Protection by Unfolded Protein Response or Epigenetic Repression

Elanchezhian Rajan; Palsamy Periyasamy; Christian J. Madson; Micheal L. Mulhern; David W. Lynch; Masahiko Ayaki; Thomas W. Hejkal; Toshimichi Shinohara

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5289.

ARVO Annual Meeting Abstract April 2010

Activation of the Unfolded Protein Response (UPR) in Age-Related Cataract Lenses

E. Rajan; C. J. Madson; M. L. Mulhern; J. Usukura; T. Shinohara

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):3817.

ARVO Annual Meeting Abstract May 2008

A Comparative Study of Current Therapies for Neovascular Age-Related Macular Degeneration

W. M. Stapleton; M. L. Mulhern; D. D. Ingvoldstad; A. A. Johansen; E. Margalit

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):592.

ARVO Annual Meeting Abstract May 2008

Chemical Chaperones and Bile Acids Protect Molecular Chaperones, -Crystallins Against Thermal Denaturation in vitro

T. Shinohara; J. Liang; S. Song; M. L. Mulhern; G. Thurston

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4504.

ARVO Annual Meeting Abstract May 2008

Chemical Chaperones and TUDCA Partially Suppress Degeneration of Retinal Photoreceptor Cells in Transgenic Mutant Rhodopsin S334ter-3 Rats

M. L. Mulhern; C. J. Madson; W. Thoreson; T. Shinohara

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):2038.

ARVO Annual Meeting Abstract May 2007

Chemical Chaperones Suppress ER Stress, LEC Death, and Cataract Formation in the Galactosemic Rat Lens

M. Mulhern; C. J. Madson; P. F. Kador; T. Shinohara

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):3185.

Lens September 2006

The Unfolded Protein Response in Lens Epithelial Cells from Galactosemic Rat Lenses

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Michael L. Mulhern; Christian J. Madson; Andrew Danford; Kengo Ikesugi; Peter F. Kador; Toshimichi Shinohara
TAGS: galactose, glucose, lens (device), lens, crystalline, proteins, rats, lens epithelial cell, unfolded protein response, cell death, stress
Invest. Ophthalmol. Vis. Sci.. 2006; 47(9):3951-3959. https://doi.org/10.1167/iovs.06-0193

ARVO Annual Meeting Abstract May 2006

Outcome of Retinopathy of Prematurity (ROP) Patients Following Adoption of Revised Indications for Treatment

A. Alme; T. Hejkal; M. Mulhern; D. Ingvoldstad; E. Margalit

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):5303.

ARVO Annual Meeting Abstract May 2006

ATF4 Binds to and Regulates the Promoter of the LEDGF Gene During the Unfolded Protein Response

M. Mulhern; K. Ikesugi; R. Yamamoto; N. Fatma; D.P. Singh; T. Shinohara

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):3516.

ARVO Annual Meeting Abstract May 2006

Hypoglycemic and Hyperglycemic Conditions Induce the Unfolded Protein Response (UPR) in Galactosemic Rat Lenses and Human Lecs in Culture

T. Shinohara; C.F. Madson; M.L. Mulhern; A. Danford; K. Ikesugi; P.F. Kador

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):4117.

ARVO Annual Meeting Abstract May 2006

Glucose Imbalance Induces the Unfolded Protein Response (UPR) in Rat Retinal Capillary Pericyte and Endothelial Cells

P.F. Kador; K. Ikesugi; M.L. Mulhern; K.–I. Hosoya; T. Terasaki; K. Blessing; T. Shinohara

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):4235.

ARVO Annual Meeting Abstract May 2005

The Unfolded Protein Response (UPR) in RDS Mouse Photoreceptor Degeneration

M. Mulhern; K. Ikesugi; R. Yamamoto; J. Usukura; Y. Nishizawa; T. Shinohara

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):1600.

ARVO Annual Meeting Abstract May 2005

The Unfolded Protein Response (UPR) Induced by Endoplasmic Reticulum (ER) Stress; A Base for Cataract Formation in Ocular Lens

K. Ikesugi; M.L. Mulhern; R. Yamamoto; T. Shinohara

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):2891.

ARVO Annual Meeting Abstract May 2005

The Unfolded Protein Response (UPR); ATF4 Directly Controls the Expression of the LEDGF Gene in LECs

T. Shinohara; K. Ikesugi; R. Yamamoto; M.L. Mulhern

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):3606.

ARVO Annual Meeting Abstract May 2004

LEDGF IS A CENTRAL TRANSCRIPTONAL ACTIVATOR FOR THE STRESS–RESISTANT GENE NETWORKS.

K. Ikesugi; M.L. Mulhern; R. Yamamoto; D.P. Singh; T. Shinohara

Invest. Ophthalmol. Vis. Sci.. 2004; 45(13):4540.

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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