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ARVO Annual Meeting Abstract June 2023

Long durability of foveal cone vision improvement after single injections of sepofarsen confirmed in a second CEP290 -LCA eye

Artur V Cideciyan; Samuel Jacobson; Allen Ho; Malgorzata Swider; Alexander Sumaroka; Alejandro J Roman; Alexandra V Garafalo; Vivian Wu; Michael Schwartz; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3833.

ARVO Annual Meeting Abstract June 2022

Long-term safety and efficacy of sepofarsen in a Ph1b/2 INSIGHT extension trial in CEP290 -associated Leber congenital amaurosis (LCA10)

Stephen R Russell; Arlene V Drack; Artur V Cideciyan; Samuel G. Jacobson; Bart P Leroy; Caroline Van Cauwenbergh; Michael Schwartz; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):453.

ARVO Annual Meeting Abstract June 2022

Efficacy and safety of sepofarsen, an intravitreal RNA antisense oligonucleotide, for the treatment of CEP290 -associated Leber congenital amaurosis (LCA10): a randomized, double-masked, sham-controlled, Phase 3 study (ILLUMINATE)

Bart Peter Leroy; Katarina Stingl; Isabelle S Audo; Camiel J F Boon; Fernanda Belga O Porto; Michel Michaelides; Helene Dollfus; L. Ingeborgh van den Born; Lyubomyr M Lytvynchuk; Francesca Simonelli; Juliana M F Sallum; Robert K Koenekoop; Elise Heon; Stephen R Russell; Michael Schwartz; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4536 – F0323.

Articles February 2022

Choriocapillaris Changes in Myopic Macular Degeneration

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Jonathan Li; Hao Zhou; Max Feinstein; Jessica Wong; Ruikang K. Wang; Lawrence Chan; Yining Dai; Travis Porco; Jacque L. Duncan; Daniel M. Schwartz
TAGS: chief complaint, fluid flow, myopic macular degeneration, eye, chorioretinal atrophy
Trans. Vis. Sci. Tech.. 2022; 11(2):37. https://doi.org/10.1167/tvst.11.2.37

ARVO Annual Meeting Abstract June 2021

Safety and efficacy of sepofarsen in the second treated eye in a Ph1b/2 extension trial in Leber Congenital Amaurosis type 10 (LCA10)

Stephen R Russell; Arlene V Drack; Artur V Cideciyan; Samuel G Jacobson; Bart Leroy; Allen Ho; Caroline Van Cauwenbergh; Arun kumar Krishnan; Wilhelmina R. den Hollender; Adriana Hollestein-Havelaar; Mike Schwartz; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3317.

ARVO Annual Meeting Abstract June 2020

Results of a phase 1b/2 trial of intravitreal (IVT) sepofarsen (QR-110) antisense oligonucleotide in Leber congenital amaurosis 10 (LCA10) due to p.Cys998X mutation in the CEP290 gene

Stephen R Russell; Arlene V Drack; Artur V Cideciyan; Samuel G Jacobson; Bart Peter Leroy; Wanda L. Pfeifer; Alina V. Dumitrescu; Alexandra V. Garafolo; Allen C. Ho; Caroline Van Cauwenbergh; Julie De Zaeytijd; Aniz Girach; Wil den Hollander; Mike Schwartz; David M. Rodman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):866.

Articles June 2020

OCT Angiography to Predict Geographic Atrophy Progression using Choriocapillaris Flow Void as a Biomarker

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Khashayar Nattagh; Hao Zhou; Nicholas Rinella; Qinqin Zhang; Yining Dai; Katharina G. Foote; Cathrine Keiner; Michael Deiner; Jacque L. Duncan; Travis C. Porco; Ruikang K. Wang; Daniel M. Schwartz
TAGS: angiogram, atrophy, biological markers, chief complaint, fluid flow
Trans. Vis. Sci. Tech.. 2020; 9(7):6. https://doi.org/10.1167/tvst.9.7.6

ARVO Annual Meeting Abstract July 2019

CEP290 -associated LCA due to a photoreceptor cilium defect treated with an intravitreal antisense oligonucleotide results in improved vision

Artur V Cideciyan; Samuel G Jacobson; Arlene V Drack; Allen C Ho; Alexandra Garafalo; Alejandro J Roman; Mike Schwartz; Patricia Biasutto; Wilma de Wit; Michael E Cheetham; Peter S Adamson; David Rodman; Julie De Zaeytijd; Caroline Van Cauwenbergh; Bart P Leroy; Stephen R Russell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1834.

Retina December 2018

OCT Angiography and Cone Photoreceptor Imaging in Geographic Atrophy

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Jia Qin; Nicholas Rinella; Qinqin Zhang; Hao Zhou; Jessica Wong; Michael Deiner; Austin Roorda; Travis C. Porco; Ruikang K. Wang; Daniel M. Schwartz; Jacque L. Duncan
TAGS: angiogram, atrophy, chief complaint, diagnostic imaging, eye, optics, retinal cone, perfusion, fluid flow
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5985-5992. https://doi.org/10.1167/iovs.18-25032

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Choriocapillaris Perfusion and Retinal Sensitivity in Areas Bordering Geographic Atrophy

Nicholas Rinella; Qinqin Zhang; Ruikang K Wang; Michael Deiner; Daniel M Schwartz; Travis Porco; Jacque L Duncan

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3236.

ARVO Annual Meeting Abstract June 2017

OCT Angiography and Cone Photoreceptor Imaging in Geographic Atrophy

Jia Qin; Nicholas Rinella; Michael Deiner; Kyle McDermott; John S Werner; Austin Roorda; Travis C Porco; Daniel M. Schwartz; Jacque L. Duncan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):368.

ARVO Annual Meeting Abstract June 2017

Greater diversity of arachadonic acid metabolites is observed in tears of diseased eyes of children compared to normal eyes

Dennis Kwon; Gerald W Zaidman; Lars Bellner; Michal Schwartzman; Katherine Gotlinger

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):973.

ARVO Annual Meeting Abstract September 2016

Cone Photoreceptor Imaging and OCT Angiography in AMD Geographic Atrophy

Jia Qin; Nicholas Rinella; Daniel M Schwartz; Michael Deiner; Kyle C. McDermott; Shane Griffin; Panagiota Loumou; John S Werner; Austin Roorda; Jacque L Duncan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4947.

Genetics March 2016

Prevalence and Genetics of Leber Hereditary Optic Neuropathy in the Danish Population

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Thomas Rosenberg; Søren Nørby; Marianne Schwartz; Juliette Saillard; Paulo J. Magalhães; David Leroy; Erik C. Kann; Morten Duno
TAGS: danish, genetics, optic atrophy, hereditary, leber, prevalence, mutation
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):1370-1375. https://doi.org/10.1167/iovs.15-18306

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

The retinal pigment epithelium as a gateway for healing macrophages into the retina

Inbal Benhar; Kitty Reemst; Vyacheslav Kalchenko; Michal Schwartz

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2076.

ARVO Annual Meeting Abstract June 2015

Patient-Reported Visual Function in Patients with Geographic Atrophy Secondary to Age-related Macular Degeneration (AMD): Baseline Characteristics of the BAM114341 Cohort

Fang Wang; Mike Fries; John I Wurzelmann; Shawn Patrick Shearn; Michael R Schwartz; Rabia Ozden; on behalf of BAM114341 Study Group

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2811.

ARVO Annual Meeting Abstract June 2015

Baseline Characteristics of BAM114341 population, a Phase II study in geographic atrophy (GA) secondary to Age-Related Macular Degeneration (AMD)

Shawn Patrick Shearn; Mike Fries; John I Wurzelmann; Francisco J Lopez; Michael R Schwartz; Rabia Ozden; Baruch Kuppermann; BAM114341 Study Group

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2840.

ARVO Annual Meeting Abstract June 2015

SNPs Associated with Complement Factor I Do Not Predict 4-month Lesion Growth Rate in Geographic Atrophy

John I Wurzelmann; Francisco J Lopez; Mike Fries; Shawn Patrick Shearn; Michael R Schwartz; Astrid Yeo; Lingkang Huang; Amitha Domalpally; Ronald P Danis; Rabia Ozden; BAM114341

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2850.

ARVO Annual Meeting Abstract April 2014

Optimization of phase-variance optical coherence tomography scanning parameters for retinal vasculature visualization

Dae Yu Kim; Justin V Migacz; Jeff Fingler; Robert J Zawadzki; Daniel M Schwartz; John S Werner; Scott Fraser; Multidisciplinary Ophthalmic Imaging

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):222.

ARVO Annual Meeting Abstract April 2014

Analysis of Patients with Wet Age-related Macular Degeneration (WAMD) Switched Back to Ranibizumab/Bevacizumab After a Trial of Aflibercept

Geraldine Rosaura Slean; Robert B Bhisitkul; Daniel M Schwartz; Jay M Stewart

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3940.

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Long durability of foveal cone vision improvement after single injections of sepofarsen confirmed in a second CEP290 -LCA eye

Long-term safety and efficacy of sepofarsen in a Ph1b/2 INSIGHT extension trial in CEP290 -associated Leber congenital amaurosis (LCA10)

Efficacy and safety of sepofarsen, an intravitreal RNA antisense oligonucleotide, for the treatment of CEP290 -associated Leber congenital amaurosis (LCA10): a randomized, double-masked, sham-controlled, Phase 3 study (ILLUMINATE)

Choriocapillaris Changes in Myopic Macular Degeneration

Safety and efficacy of sepofarsen in the second treated eye in a Ph1b/2 extension trial in Leber Congenital Amaurosis type 10 (LCA10)

Results of a phase 1b/2 trial of intravitreal (IVT) sepofarsen (QR-110) antisense oligonucleotide in Leber congenital amaurosis 10 (LCA10) due to p.Cys998X mutation in the CEP290 gene

OCT Angiography to Predict Geographic Atrophy Progression using Choriocapillaris Flow Void as a Biomarker

CEP290 -associated LCA due to a photoreceptor cilium defect treated with an intravitreal antisense oligonucleotide results in improved vision

OCT Angiography and Cone Photoreceptor Imaging in Geographic Atrophy

Choriocapillaris Perfusion and Retinal Sensitivity in Areas Bordering Geographic Atrophy

OCT Angiography and Cone Photoreceptor Imaging in Geographic Atrophy

Greater diversity of arachadonic acid metabolites is observed in tears of diseased eyes of children compared to normal eyes

Cone Photoreceptor Imaging and OCT Angiography in AMD Geographic Atrophy

Prevalence and Genetics of Leber Hereditary Optic Neuropathy in the Danish Population

The retinal pigment epithelium as a gateway for healing macrophages into the retina

Patient-Reported Visual Function in Patients with Geographic Atrophy Secondary to Age-related Macular Degeneration (AMD): Baseline Characteristics of the BAM114341 Cohort

Baseline Characteristics of BAM114341 population, a Phase II study in geographic atrophy (GA) secondary to Age-Related Macular Degeneration (AMD)

SNPs Associated with Complement Factor I Do Not Predict 4-month Lesion Growth Rate in Geographic Atrophy

Optimization of phase-variance optical coherence tomography scanning parameters for retinal vasculature visualization

Analysis of Patients with Wet Age-related Macular Degeneration (WAMD) Switched Back to Ranibizumab/Bevacizumab After a Trial of Aflibercept

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