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Lens September 2020

Cohen Syndrome-Associated Cataract Is Explained by VPS13B Functions in Lens Homeostasis and Is Modified by Additional Genetic Factors

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Vincent Lhussiez; Elisabeth Dubus; Quénol Cesar; Niyazi Acar; Emeline F. Nandrot; Manuel Simonutti; Isabelle Audo; Eléonore Lizé; Sylvie Nguyen; Audrey Geissler; André Bouchot; Muhammad Ansar; Serge Picaud; Christel Thauvin-Robinet; Laurence Olivier-Faivre; Laurence Duplomb; Romain Da Costa
TAGS: cataract, lens (device), lens, crystalline, genetic aspects, cohen syndrome, mice, syndrome, homeostasis
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):18. https://doi.org/10.1167/iovs.61.11.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

The development of a therapy for retinitis pigmentosa based on the combined administration of the two products encoded by the nucleoredoxin like-1 gene

Emmanuelle Clerin; Ying Yang; Delphine Pagan; Seiki Achiedo; Julie Degardin; Quénol Cesar; Manuel Simonutti; Géraldine Millet-puel; Frédéric Blond; Najate Ait-Ali; José-Alain Sahel; Thierry Leveillard

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3963.

Retina September 2016

Quantitative and Topographical Analysis of the Losses of Cone Photoreceptors and Retinal Ganglion Cells Under Taurine Depletion

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Wahiba Hadj-Saïd; Nicolas Froger; Ivana Ivkovic; Manuel Jiménez-López; Élisabeth Dubus; Julie Dégardin-Chicaud; Manuel Simonutti; César Quénol; Nathalie Neveux; María Paz Villegas-Pérez; Marta Agudo-Barriuso; Manuel Vidal-Sanz; Jose-Alain Sahel; Serge Picaud; Diego García-Ayuso
TAGS: retina, retinal cone, taurine, retinal degeneration, retinal ganglion cells, mice, opsin
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4692-4703. https://doi.org/10.1167/iovs.16-19535

ARVO Annual Meeting Abstract June 2015

Retinal distribution of cone and retinal ganglion cell degenerations in taurine-depleted mice

Wahiba Hadj Said; Diego García-Ayuso; Nicolas G Froger; Ivana Ivkovic; Manuel Jiménez-López; Julie Degardin; Manuel SIMONUTTI; Manuel Vidal-Sanz; Jose Alain Sahel; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4646.

ARVO Annual Meeting Abstract June 2015

3 months kinetics of Type 1 Diabetes model in Brown Norway rats : Retinal phenotypes and molecular analysis

Provost Alexandra; Brahim El Mathari; Alexandra Trehin; Carine Bernard; Damien Lavier; Annabelle Amiard; Manuel SIMONUTTI; Anais Potey; Samantha Beck; Thomas Debeir

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5182.

ARVO Annual Meeting Abstract June 2015

Cone rescue depends on Rod-derived Cone Viability Factor

Ying Yang; Emmanuelle Clerin; Manuel SIMONUTTI; celine Jaillard; Stephane Fouquet; José-Alain Sahel; Thierry D Leveillard

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5444.

ARVO Annual Meeting Abstract June 2015

Microglial activation in a rat model of NAION

Anne-Laure Remond; Audrey Fel; Manuel SIMONUTTI; Ivana IVKOVIC; Jose Alain Sahel; Phuc LeHoang; Bahram Bodaghi; Serge A Picaud; Valerie Touitou

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5542.

ARVO Annual Meeting Abstract April 2014

Visual phenotyping in mutant mice deleted for the taurine-transporter gene

Wahiba HADJ SAÏD; Nicolas G Froger; Ivana Ivkovic; Manuel Simonutti; Nathalie Neveux; Takashi Ito; Junichi Azuma; José-Alain Sahel; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2362.

ARVO Annual Meeting Abstract April 2014

Minocycline as a neuroprotective agent in a rodent model of NAION

Audrey Fel; Nicolas G Froger; Manuel Simonutti; Steven L Bernstein; Neil Miller; Bahram Bodaghi; Phuc Lehoang; Serge A Picaud; Michel Paques; Valerie Touitou

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5736.

ARVO Annual Meeting Abstract June 2013

The retinal phenotype of an animal model of the HANAC syndrome

Alix Trouillet; Emmanuelle Plaisier; Henri Lorach; Julie Dégardin; Manuel Simonutti; Michel Paques; Jose Sahel; Pierre Ronco; Serge Picaud

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5094.

ARVO Annual Meeting Abstract March 2012

Design of a clinical study of gene therapy for Leber Hereditary Optic Neuropathy

Helene Cwerman-Thibault; Sebastien Augustin; Christophe Lechauve; Jessica Ayache; Manuel Simonutti; Jose-Alain Sahel; Marisol Corral-Debrinski

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1913.

ARVO Annual Meeting Abstract April 2011

Taurine Deficiency Damages Retinal Neurones, Cone Photoreceptors And Retinal Ganglion Cells

David Gaucher; Emilie Arnault; Elisabeth Dubus; Julie Degardin; Manuel Simonutti; Tristan Bourcier; Claude Speeg-Schatz; Jose Alain Sahel; Serge Picaud

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5436.

ARVO Annual Meeting Abstract April 2011

Long-term Transgene Expression And Safety Of a rAAV2 Approach Of Gene Therapy For Leber Hereditary Optic Neuropathy

Helene Cwerman-Thibault; Sebastien Augustin; Aicha Bouaita; Christophe Lechauve; Soufien Sghari; Manuel Simonutti; Michel Paques; Pierre Rustin; Jose A. Sahel; Marisol C. Debrinsky, IV

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1405.

ARVO Annual Meeting Abstract April 2011

Suitability Of A Novel Human Multimodal Slit-lamp Sd-oct To Image Animal Eyes

Serge G. Rosolen; Sylvie Lavillegrand; Mei-Lyn Riviere; Manuel Simonutti; Jose-Alain Sahel; Serge Picaud; Jean-Francois LeGargasson

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1727.

ARVO Annual Meeting Abstract April 2011

A Neuroprotective Molecule For Retinal Ganglion Cells In Different Cellular And Animal Models Of Glaucoma

Nicolas G. Froger; Julie Dégardin; Dorothée Pain; Elisabeth Dubus; Valérie Forster; Manuel Simonutti; Alexis-Pierre Bemelmans; José-Alain Sahel; Serge Picaud

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1874.

ARVO Annual Meeting Abstract April 2010

Harlequin Mouse: An Appropriate Model for Studying Progressive Visual Function Loss Due to Retinal Ganglion Cell and Photoreceptor Degeneration

A. Bouaita; H. Cwerman-Thibault; S. Augustin; P. Benit; M. Simonutti; M. Paques; P. Rustin; J. Sahel; M. Corral Debrinski

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):3649.

ARVO Annual Meeting Abstract April 2010

Photoreceptor Transplantation Rescues Cones by Reversing Cell Damage Morphology

Y. Yang; S. Mohand-said; M. Simonutti; S. Fouquet; T. Léveillard; J.-A. Sahel

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):3708.

ARVO Annual Meeting Abstract April 2010

Erg Responses in the Dystrophin Dp71-Null Mice

D. Cia; M. Simonutti; A. Sene; R. Benard; M. Roux; M. Doly; J. Sahel; A. Rendon

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):4033.

ARVO Annual Meeting Abstract April 2010

In vivo Observation of the Locomotion of Microglial Cells in the Retina of Wild-Type Rodents

M. Paques; M. Simonutti; B. El Mathari; J.-A. Sahel

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):5347.

ARVO Annual Meeting Abstract April 2010

A Faithful Model of Optic Neuropathy Created by an Induced Nd4 Gene Heteroplasmy

M. C. Debrinsky, IV; S. Ellouze; S. Augustin; A. Bouaita; H. Cwerman-Thilbault; M. Simonutti; M. Paques; P. Rustin; J.-A. Sahel

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):3137.

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Cohen Syndrome-Associated Cataract Is Explained by VPS13B Functions in Lens Homeostasis and Is Modified by Additional Genetic Factors

The development of a therapy for retinitis pigmentosa based on the combined administration of the two products encoded by the nucleoredoxin like-1 gene

Quantitative and Topographical Analysis of the Losses of Cone Photoreceptors and Retinal Ganglion Cells Under Taurine Depletion

Retinal distribution of cone and retinal ganglion cell degenerations in taurine-depleted mice

3 months kinetics of Type 1 Diabetes model in Brown Norway rats : Retinal phenotypes and molecular analysis

Cone rescue depends on Rod-derived Cone Viability Factor

Microglial activation in a rat model of NAION

Visual phenotyping in mutant mice deleted for the taurine-transporter gene

Minocycline as a neuroprotective agent in a rodent model of NAION

The retinal phenotype of an animal model of the HANAC syndrome

Design of a clinical study of gene therapy for Leber Hereditary Optic Neuropathy

Taurine Deficiency Damages Retinal Neurones, Cone Photoreceptors And Retinal Ganglion Cells

Long-term Transgene Expression And Safety Of a rAAV2 Approach Of Gene Therapy For Leber Hereditary Optic Neuropathy

Suitability Of A Novel Human Multimodal Slit-lamp Sd-oct To Image Animal Eyes

A Neuroprotective Molecule For Retinal Ganglion Cells In Different Cellular And Animal Models Of Glaucoma

Harlequin Mouse: An Appropriate Model for Studying Progressive Visual Function Loss Due to Retinal Ganglion Cell and Photoreceptor Degeneration

Photoreceptor Transplantation Rescues Cones by Reversing Cell Damage Morphology

Erg Responses in the Dystrophin Dp71-Null Mice

In vivo Observation of the Locomotion of Microglial Cells in the Retina of Wild-Type Rodents

A Faithful Model of Optic Neuropathy Created by an Induced Nd4 Gene Heteroplasmy

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