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Retina November 2024

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

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Akishi Onishi; Yuji Tsunekawa; Michiko Mandai; Aiko Ishimaru; Yoko Ohigashi; Junki Sho; Kazushi Yasuda; Keiichiro Suzuki; Juan Carlos Izpisua Belmonte; Fumio Matsuzaki; Masayo Takahashi
TAGS: genes, genome editing, mice, retinitis pigmentosa, rhodopsin, rod photoreceptors, donors, plasmids, electroporation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):38. https://doi.org/10.1167/iovs.65.13.38

Includes: Supplemental Content

Retinal Cell Biology October 2024

Host-Graft Synapses Form Functional Microstructures and Shape the Host Light Responses After Stem Cell-Derived Retinal Sheet Transplantation

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Ryutaro Akiba; Hung-Ya Tu; Tomoyo Hashiguchi; Yoshiko Takahashi; Kiminori Toyooka; Yoshihiko Tsukamoto; Takayuki Baba; Masayo Takahashi; Michiko Mandai
TAGS: synapses, tissue transplants, transplantation, photoreceptors, shape, retinal bipolar cells
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):8. https://doi.org/10.1167/iovs.65.12.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Fast differentiation of human retinal organoids from pluripotent stem cells manipulated by Sonic Hedgehog, Activin A and retinoic acid signaling

Tokiyoshi Matsushita; Akishi Onishi; Takahiro Matsuyama; Tomohiro Masuda; Yoko Ogino; Masaaki Kageyama; Masayo Takahashi; Fumiaki Uchiumi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4522.

ARVO Annual Meeting Abstract June 2024

Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) study: Report on recruitment strategy and pilot data collection

Alina Ferguson; Cari Drolet; Trina Kim; Cath Ashley; Julia Owen; Missy Takahashi; Dawn Mathies; Shay Paselio; Sally Liu Baxter; Aaron Y Lee; Linda M Zangwill; Cecilia S Lee; Gerald McGwin; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3727.

ARVO Annual Meeting Abstract June 2024

Eye Adult Changes in Thought (Eye ACT) study: Settings and report on the inaugural cohort

Kevin Zhao; Christina Duong; Caitlyn Ngadisastra; Missy Takahashi; Beth Pope; Beverly Schaaf; Julie Cooper; Jason Kam; Michael Brush; Laura Gibbons; Aaron Y. Lee; David Arteburn; Eric Larson; Paul K. Crane; Cecilia S Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6367.

ARVO Annual Meeting Abstract June 2024

Retinal and choroidal changes in patients with dementia assessed by swept-source optical coherence tomography angiography

Yi Zhang; Yu Jiang; Christina Duong; Missy Takahashi; Yufen Lin; Suman Jayadev; Yue Wu; Aaron Y. Lee; Cecilia S Lee; Ruikang K Wang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3893.

ARVO Annual Meeting Abstract June 2024

Graft cell expansion from hiPSC-RPE strip after transplantation in primate eyes with or without RPE damage

Michiko Mandai; Keisuke Kajita; Mitsuhiro Nishida; Yasuo Kurimoto; Satoshi Yokota; Sunao Sugita; Atsuta Ozaki; Yoko Miura; Masayo Takahashi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):409.

ARVO Annual Meeting Abstract June 2024

Genomic characterization of human pluripotent stem cell-derived RAX-positive sub-populations that direct retinal layer structuring and non-retinal tissue

Yasuaki Iwama; Tomohiro Masuda; Mika Yoshimura; Michiru Matsumura; Kanako Kawai; Kohji Nishida; Masayo Takahashi; Itoshi Nikaido; Michiko Mandai

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4529.

ARVO Annual Meeting Abstract June 2024

Accuracy and Repeatability of a New Multimodal Diagnostic Prototype Compared to Standard Methods

Ece Turhal; Nevin W. El-Nimri; Juan D. Arias; Mary Durbin; Mayra Tafreshi; Amy Minshall; Yukari Kanemichi; Akihiro Harada; Masahiro Takahashi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5546.

ARVO Annual Meeting Abstract June 2024

Morphological and Molecular Insights into Early Degeneration of Retinal Pigment Epithelium in Middle-Aged Aldh1a1 Knockout Mice

So Goto; Akishi Onishi; Seth Blackshaw; Conover Talbot; Masayo Takahashi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6742.

ARVO Annual Meeting Abstract June 2023

Evaluation of ophthalmic biomarkers of dementia

Yvonne Hong; Christina Duong; Megan Lacy; Oliver Davidson; Missy Takahashi; Suman Jaydev; Cecilia S. Lee; Aaron Y Lee

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3676.

ARVO Annual Meeting Abstract June 2023

Induced pluripotent stem cell derived retinal organoid sheets for regenerative therapy in patients with end-stage retinitis pigmentosa

Michiko Mandai; Yasuhiko Hirami; Sunao Sugita; Akiko Maeda; tadao Maeda; Midori Yamamoto; Hirofumi Uyama; Satoshi Yokota; Masashi Fujihara; Masataka Igeta; Takashi Daimon; Kanako Fujita; Tomoko Ito; Masayo Takahashi; Yasuo Kurimoto

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4628.

ARVO Annual Meeting Abstract June 2023

Analysis of prospective data from the Eye Adult Changes in Thought study

Christina Duong; Oliver Davidson; Yvonne Hong; Beth Pope; Jason Kam; Michael Brush; Megan Lacy; Julie Cooper; Missy Takahashi; Eric Larson; David Arterburn; Paul Crane; Aaron Lee; Cecilia S Lee

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4242.

ARVO Annual Meeting Abstract June 2022

Rewiring of the adult midget pathway in a primate model of acute photoreceptor loss.

Ryutaro Akiba; Shane Boniec; Hirofumi Uyama; Hung-Ya Tu; Sharm Knecht; Takayuki Baba; Masayo Takahashi; Michiko Mandai; Rachel Wong

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3132.

Retinal Cell Biology October 2021

Transplanted Mouse Embryonic Stem Cell–Derived Retinal Ganglion Cells Integrate and Form Synapses in a Retinal Ganglion Cell-Depleted Mouse Model

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You-Ren Wu; Tomoyo Hashiguchi; Junki Sho; Shih-Hwa Chiou; Masayo Takahashi; Michiko Mandai
TAGS: embryonic stem cells, mice, n-methylaspartate, retina, retinal ganglion cells, tissue transplants, transplantation, stem cells, synapses, neurites
Invest. Ophthalmol. Vis. Sci.. 2021; 62(13):26. https://doi.org/10.1167/iovs.62.13.26

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Retinal dysfunction and visual impairment in aged Aldh1a1 knockout mice

So Goto; Akishi Onishi; Yoko Ohigashi; Hiromi Endoh; Shigenobu Yonemura; Hirokazu Sakaguchi; Kohji Nishida; Masayo Takahashi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1235.

ARVO Annual Meeting Abstract July 2019

Automated cell culture for the differentiation of induced pluripotent stem cells into retinal pigment epithelial cells by LabDroid

Naohiro Motozawa; Akitaka Tsujikawa; Masayo Takahashi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3319.

ARVO Annual Meeting Abstract July 2019

Low immunogenicity and immunosuppressive property of human ES/iPS cells derived neural retina

Suguru Yamasaki; Sunao Sugita; Matsuri Horiuchi; atsushi kuwahara; Akiyoshi Kishino; Toru Kimura; Masayo Takahashi; Michiko Mandai

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3927.

ARVO Annual Meeting Abstract July 2019

Effect of ambient light and BDNF on photoreceptor synaptogenesis after mouse ESC/iPSC-derived retinal organoid transplantation

Ryutaro Akiba; Take Matsuyama; Hung-Ya Tu; Tomoyo Hashiguchi; Sho Junki; Shuichi Yamamoto; Yasuhiko Tabata; Masayo Takahashi; Michiko Mandai

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3928.

ARVO Annual Meeting Abstract July 2019

Functional examination of genetically engineered human ESC-retinas transplanted in an immunodeficient rat model with retinal degeneration

Hung-Ya Tu; Suguru Yamasaki; atsushi kuwahara; Akiyoshi Kishino; Toru Kimura; Masayo Takahashi; Michiko Mandai

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3929.

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Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

Host-Graft Synapses Form Functional Microstructures and Shape the Host Light Responses After Stem Cell-Derived Retinal Sheet Transplantation

Fast differentiation of human retinal organoids from pluripotent stem cells manipulated by Sonic Hedgehog, Activin A and retinoic acid signaling

Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) study: Report on recruitment strategy and pilot data collection

Eye Adult Changes in Thought (Eye ACT) study: Settings and report on the inaugural cohort

Retinal and choroidal changes in patients with dementia assessed by swept-source optical coherence tomography angiography

Graft cell expansion from hiPSC-RPE strip after transplantation in primate eyes with or without RPE damage

Genomic characterization of human pluripotent stem cell-derived RAX-positive sub-populations that direct retinal layer structuring and non-retinal tissue

Accuracy and Repeatability of a New Multimodal Diagnostic Prototype Compared to Standard Methods

Morphological and Molecular Insights into Early Degeneration of Retinal Pigment Epithelium in Middle-Aged Aldh1a1 Knockout Mice

Evaluation of ophthalmic biomarkers of dementia

Induced pluripotent stem cell derived retinal organoid sheets for regenerative therapy in patients with end-stage retinitis pigmentosa

Analysis of prospective data from the Eye Adult Changes in Thought study

Rewiring of the adult midget pathway in a primate model of acute photoreceptor loss.

Transplanted Mouse Embryonic Stem Cell–Derived Retinal Ganglion Cells Integrate and Form Synapses in a Retinal Ganglion Cell-Depleted Mouse Model

Retinal dysfunction and visual impairment in aged Aldh1a1 knockout mice

Automated cell culture for the differentiation of induced pluripotent stem cells into retinal pigment epithelial cells by LabDroid

Low immunogenicity and immunosuppressive property of human ES/iPS cells derived neural retina

Effect of ambient light and BDNF on photoreceptor synaptogenesis after mouse ESC/iPSC-derived retinal organoid transplantation

Functional examination of genetically engineered human ESC-retinas transplanted in an immunodeficient rat model with retinal degeneration

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