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Retinal Cell Biology April 2024

Dose-Related Side Effects of Intravitreal Injections of Humanized Anti-Vascular Endothelial Growth Factor in Rats: Glial Cell Reactivity and Retinal Ganglion Cell Loss

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Ana Martínez-Vacas; Johnny Di Pierdomenico; Ana María Gómez-Ramirez; Manuel Vidal-Sanz; María P. Villegas-Pérez; Diego García-Ayuso
TAGS: adverse effects, aflibercept, antibodies, anti-vascular endothelial growth factor therapy, endothelial growth factors, eye, intravitreal injections, mass or substance concentration per volume, neuroglia, painful bladder syndrome
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):10. https://doi.org/10.1167/iovs.65.4.10

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Changes in cytokine and growth factor levels at different time points after experimental glaucoma induction.

Jose A. Fernández-Albarral; Ana Ramirez; Rosa de Hoz; Meritxell López-Gallardo; Eva M. Marco; Elena Salobrar-García; Inés López Cuenca; Beatriz Martín-Sánchez; Elena Flores-Salguero; Marcelino Avilés-Trigueros; Manuel A Vidal-Sanz; Juan J. Salazar; Jose Ramirez

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):733.

ARVO Annual Meeting Abstract June 2021

Microglial activation in healthy retina and experimental glaucoma during aging.

Ana Ramirez; Jose A. Fernández-Albarral; Inés López Cuenca; Elena Salobrar-García; Pilar Rojas; Rosa de Hoz; Marcelino Avilés-Trigueros; Manuel A Vidal-Sanz; Jose Ramirez; Juan J. Salazar

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2370.

ARVO Annual Meeting Abstract June 2020

7,8-Dihydroxyflavone protects axotomy-induced retinal ganglion cell loss in adult albino rats.

Manuel A Vidal-Sanz; Beatriz Vidal-Villegas; Johnny Di Pierdomenico; Alejandro Gallego-Ortega; Caridad Galindo-Romero; Jose M Bernal-Garro; Marta Agudo-Barriuso; Jose Maria Martinez de la Casa; José María García-Feijo; Maria Paz Villegas-Perez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):647.

Retinal Cell Biology March 2020

Coordinated Intervention of Microglial and Müller Cells in Light-Induced Retinal Degeneration

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Johnny Di Pierdomenico; Ana Martínez-Vacas; Daniel Hernández-Muñoz; Ana M. Gómez-Ramírez; Francisco Javier Valiente-Soriano; Marta Agudo-Barriuso; Manuel Vidal-Sanz; María P. Villegas-Pérez; Diego García-Ayuso
TAGS: neuroglia, photoreceptors, phototoxicity, retina, retinal cone, retinal degeneration, tissue degeneration, microglia, light exposure
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):47. https://doi.org/10.1167/iovs.61.3.47

Articles December 2019

Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity

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Francisco J. Valiente-Soriano; Arturo Ortín-Martínez; Johnny Di Pierdomenico; Diego García-Ayuso; Alejandro Gallego-Ortega; Juan A. Miralles de Imperial-Ollero; Manuel Jiménez-López; María Paz Villegas-Pérez; Larry A. Wheeler; Manuel Vidal-Sanz
TAGS: brain-derived neurotrophic factor, brimonidine, ciliary neurotrophic factor, fibroblast growth factor 2, lip, phototoxicity, retina, retinal cone, opsin, mice
Trans. Vis. Sci. Tech.. 2019; 8(6):36. https://doi.org/10.1167/tvst.8.6.36

ARVO Annual Meeting Abstract July 2019

Adenosine A3 receptor agonist prevents the loss of retinal ganglion cells in a glaucoma model

Raquel Boia; Manuel Salinas-Navarro; Alejandro Gallego-Ortega; Caridad Galindo-Romero; Marta Agudo-Barriuso; Antonio F Ambrosio; Manuel Vidal-Sanz; Ana Raquel Santiago

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):625.

Retina September 2018

Neuroprotective Effects of FGF2 and Minocycline in Two Animal Models of Inherited Retinal Degeneration

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Johnny Di Pierdomenico; Rebecca Scholz; F. Javier Valiente-Soriano; Maria C. Sánchez-Migallón; Manuel Vidal-Sanz; Thomas Langmann; Marta Agudo-Barriuso; Diego García-Ayuso; María Paz Villegas-Pérez
TAGS: animal model, fibroblast growth factor 2, minocycline, neuroprotective effect, photoreceptors, retinal degeneration, ciliary neurotrophic factor, rats
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4392-4403. https://doi.org/10.1167/iovs.18-24621

Retina March 2018

Taurine Depletion Causes ipRGC Loss and Increases Light-Induced Photoreceptor Degeneration

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Diego García-Ayuso; Johnny Di Pierdomenico; Wahiba Hadj-Said; Mélanie Marie; Marta Agudo-Barriuso; Manuel Vidal-Sanz; Serge Picaud; María P. Villegas-Pérez
TAGS: retinal degeneration, taurine, tissue degeneration, retinal cone, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1396-1409. https://doi.org/10.1167/iovs.17-23258

ARVO Annual Meeting Abstract June 2017

Neuroprotective effect of mesenchymal stem cells isolated from the Wharton’s jelly of the human umbilical cord

Marta Agudo-Barriuso; José E Millan-Rivero; Francisco M Nadal-Nicolas; David García-Bernal; Paloma Sobrado-Calvo; Miguel Blanquer; Manuel Vidal-Sanz; Jose M Moraleda

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1367.

ARVO Annual Meeting Abstract June 2017

Differential and additive effects of bFGF and minocycline in two animal models of inherited retinal degeneration.

Johnny Di Pierdomenico; Diego Garcia-Ayuso; Marta Agudo-Barriuso; Manuel Vidal-Sanz; Maria Paz Villegas-Perez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4549.

ARVO Annual Meeting Abstract June 2017

The effect of light exposure in the population of different retinal neurons under taurine depletion

Diego Garcia-Ayuso; Johnny Di Pierdomenico; Wahiba Hadj Said; Melanie MARIE; Marta Agudo-Barriuso; Manuel Vidal-Sanz; Serge A Picaud; Maria Paz Villegas-Perez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):290.

Glaucoma December 2016

Melanopsin-Containing or Non-Melanopsin–Containing Retinal Ganglion Cells Response to Acute Ocular Hypertension With or Without Brain-Derived Neurotrophic Factor Neuroprotection

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Giuseppe Rovere; Francisco M. Nadal-Nicolás; Jiawei Wang; Jose M. Bernal-Garro; Nuria García-Carrillo; Maria Paz Villegas-Pérez; Marta Agudo-Barriuso; Manuel Vidal-Sanz
TAGS: brain-derived neurotrophic factor, melanopsin, neuroprotection, ocular hypertension, retinal ganglion cells, eye, retina
Invest. Ophthalmol. Vis. Sci.. 2016; 57(15):6652-6661. https://doi.org/10.1167/iovs.16-20146

Includes: Supplemental Content

Retinal Cell Biology November 2016

Topical Treatment With Bromfenac Reduces Retinal Gliosis and Inflammation After Optic Nerve Crush

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Giuseppe Rovere; Francisco M. Nadal-Nicolás; Paloma Sobrado-Calvo; David García-Bernal; Maria Paz Villegas-Pérez; Manuel Vidal-Sanz; Marta Agudo-Barriuso
TAGS: bromfenac, gliosis, inflammation, optic nerve, retina
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6098-6106. https://doi.org/10.1167/iovs.16-20425

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Study of the neuroprotective effects of BDNF, bFGF, CNTF or several doses of PEDF in a focal Light-emission-diode (LED) - induced phototoxicity model in adult albino mice

F Javier Valiente-Soriano; Diego García-Ayuso; Arturo Ortin-Martinez; Manuel Jimenez-Lopez; Yolanda Caja-Matas; Antonio Cánovas-León; Jose Manuel Bernal-Garro; S Patricia Becerra; María Paz Villegas-Pérez; Manuel Vidal-Sanz

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):186.

ARVO Annual Meeting Abstract September 2016

Quantitative and topographical microglial cell changes in the ganglion cell layer and inner plexiform layer after optic nerve axotomy

Manuel Vidal-Sanz; Francisco M Nadal-Nicolas; Paloma Sobrado-Calvo; Manuel Jimenez-Lopez; Giuseppe Rovere; Maria C Sanchez-Migallon; Leticia Nieto-Lopez; Fernando Lucas-Ruiz; Manuel Salinas-Navarro; Marta Agudo-Barriuso

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2226.

ARVO Annual Meeting Abstract September 2016

Glial cell activation and migration during photoreceptor death in two rat models of inherited retinal degeneration.

Johnny Di Pierdomenico; Diego García-Ayuso; Marta Agudo-Barriuso; Manuel Vidal-Sanz; María Paz Villegas-Pérez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2241.

ARVO Annual Meeting Abstract September 2016

Repeated intravitreal injections cause stronger microglial and macroglial reactions than single injections

María Paz Villegas-Pérez; Johnny Di Pierdomenico; Diego Garcia-Ayuso; Manuel Jimenez-Lopez; Ana María Gómez-Ramírez; Marta Agudo-Barriuso; Manuel Vidal-Sanz

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2676.

ARVO Annual Meeting Abstract September 2016

Phototoxicity causes a transient downregulation of melanopsin in the rat retina.

Diego García-Ayuso; Caridad Galindo-Romero; Johnny Di Pierdomenico; Jose Manuel Bernal-Garro; Marcelino Avilés-Trigueros; Manuel Vidal-Sanz; Marta Agudo-Barriuso; María Paz Villegas-Pérez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2747.

Retina September 2016

Quantitative and Topographical Analysis of the Losses of Cone Photoreceptors and Retinal Ganglion Cells Under Taurine Depletion

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Wahiba Hadj-Saïd; Nicolas Froger; Ivana Ivkovic; Manuel Jiménez-López; Élisabeth Dubus; Julie Dégardin-Chicaud; Manuel Simonutti; César Quénol; Nathalie Neveux; María Paz Villegas-Pérez; Marta Agudo-Barriuso; Manuel Vidal-Sanz; Jose-Alain Sahel; Serge Picaud; Diego García-Ayuso
TAGS: retina, retinal cone, taurine, retinal degeneration, retinal ganglion cells, mice, opsin
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4692-4703. https://doi.org/10.1167/iovs.16-19535

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Dose-Related Side Effects of Intravitreal Injections of Humanized Anti-Vascular Endothelial Growth Factor in Rats: Glial Cell Reactivity and Retinal Ganglion Cell Loss

Changes in cytokine and growth factor levels at different time points after experimental glaucoma induction.

Microglial activation in healthy retina and experimental glaucoma during aging.

7,8-Dihydroxyflavone protects axotomy-induced retinal ganglion cell loss in adult albino rats.

Coordinated Intervention of Microglial and Müller Cells in Light-Induced Retinal Degeneration

Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity

Adenosine A3 receptor agonist prevents the loss of retinal ganglion cells in a glaucoma model

Neuroprotective Effects of FGF2 and Minocycline in Two Animal Models of Inherited Retinal Degeneration

Taurine Depletion Causes ipRGC Loss and Increases Light-Induced Photoreceptor Degeneration

Neuroprotective effect of mesenchymal stem cells isolated from the Wharton’s jelly of the human umbilical cord

Differential and additive effects of bFGF and minocycline in two animal models of inherited retinal degeneration.

The effect of light exposure in the population of different retinal neurons under taurine depletion

Melanopsin-Containing or Non-Melanopsin–Containing Retinal Ganglion Cells Response to Acute Ocular Hypertension With or Without Brain-Derived Neurotrophic Factor Neuroprotection

Topical Treatment With Bromfenac Reduces Retinal Gliosis and Inflammation After Optic Nerve Crush

Study of the neuroprotective effects of BDNF, bFGF, CNTF or several doses of PEDF in a focal Light-emission-diode (LED) - induced phototoxicity model in adult albino mice

Quantitative and topographical microglial cell changes in the ganglion cell layer and inner plexiform layer after optic nerve axotomy

Glial cell activation and migration during photoreceptor death in two rat models of inherited retinal degeneration.

Repeated intravitreal injections cause stronger microglial and macroglial reactions than single injections

Phototoxicity causes a transient downregulation of melanopsin in the rat retina.

Quantitative and Topographical Analysis of the Losses of Cone Photoreceptors and Retinal Ganglion Cells Under Taurine Depletion

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