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Retina April 2025

The Exponential Constriction Model of the Ellipsoid Zone in Taiwanese Individuals With RPGR-Related X-Linked Retinitis Pigmentosa

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Yi-Han Huang; Yu-Shu Huang; Chien-Yu Lin; Ying-Ju Lai; Chang-Hao Yang; Tzzy-Chang Ho; Yi-Ting Hsieh; Po-Ting Yeh; Tso-Ting Lai; Chao-Wen Lin; Chung-May Yang; Pei-Lung Chen; Ta-Ching Chen
TAGS: constriction procedure, disease progression, retinitis pigmentosa, taiwanese, x-linked inheritance, eye, phenotype, exons
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):59. https://doi.org/10.1167/iovs.66.4.59

Includes: Supplemental Content

Retinal Cell Biology February 2025

Remote Preconditioning Provides Protection Against Retinal Cell Death From Retinal Detachment

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Bruna Miglioranza Scavuzzi; Sumathi Shanmugam; Mengling Yang; Jingyu Yao; Heather Hager; Bhavneet Kaur; Lin Jia; Steven F. Abcouwer; David N. Zacks
TAGS: cell death, eye, retinal detachment, rna, messenger, retina, mice, dna fragmentation
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):34. https://doi.org/10.1167/iovs.66.2.34

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2025

Elevated Very-Long-Chain Ceramides in the Vitreous Humor of Patients With Proliferative Diabetic Retinopathy

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Ying-Yi Chen; Chung-May Yang; Chang-Hao Yang; Tzyy-Chang Ho; Yi-Ting Hsieh; Tso-Ting Lai; Tzu-Hsun Tsai; Shu-Yi Huang
TAGS: ceramides, vitreous body, diabetic retinopathy, proliferative diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):28. https://doi.org/10.1167/iovs.66.2.28

Cornea January 2025

ROCK Inhibitor Enhances Resilience Against Metabolic Stress Through Increasing Bioenergetic Capacity in Corneal Endothelial Cells

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Wei-Ting Ho; Jung-Shen Chang; Chia-Jen Lei; Tsan-Chi Chen; Jia-Kang Wang; Shu-Wen Chang; Muh-Hwa Yang; Tzuu-Shuh Jou; I-Jong Wang
TAGS: cornea, endothelial cells, metabolic stress, monensin, sodium, stress, chronic exertional compartment syndrome, apoptosis, glycolysis, mitochondria
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):51. https://doi.org/10.1167/iovs.66.1.51

Includes: Supplemental Content

Biochemistry and Molecular Biology January 2025

Pyrimidinergic P2Y1-Like Nucleotide Receptors Are Functional in Rat Conjunctival Goblet Cells

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Ketil A. Fjærvoll; Haakon K. Fjærvoll; Menglu Yang; Jeffrey Bair; Tor P. Utheim; Darlene A. Dartt
TAGS: agonists, conjunctiva, goblet cells, nucleotides, purinoceptor p2y1, bodily secretions, mucins, rna, small interfering
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):46. https://doi.org/10.1167/iovs.66.1.46

Includes: Supplemental Content

Visual Neuroscience October 2024

The Short- and Long-Term Perceptual Learning of Clinical Dynamic Visual Acuity Test

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Xiaobing Wang; Mingxin Yan; Jingmin Li; Yuexin Wang
TAGS: learning, motion, perceptual learning, visual acuity testing
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):43. https://doi.org/10.1167/iovs.65.12.43

Cornea October 2024

Mesenchymal Stem Cells-Derived Exosomal miR-223-3p Alleviates Ocular Surface Damage and Inflammation by Downregulating Fbxw7 in Dry Eye Models

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Guifang Wang; Yujie Zhu; Yuzhen Liu; Mulin Yang; Li Zeng
TAGS: bacterial artificial chromosomes, blood alcohol concentration, bronchioloalveolar carcinoma, dry eye syndromes, f-box-wd repeat-containing protein 7, fbxw7 gene, inflammation, mice, ocular surfaces, cornea
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):1. https://doi.org/10.1167/iovs.65.12.1

Includes: Supplemental Content

Retinal Cell Biology September 2024

ER Stress and Mitochondrial Perturbations Regulate Cell Death in Retinal Detachment: Exploring the Role of HIF1α

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Bhavneet Kaur; Bruna Miglioranza Scavuzzi; Mengling Yang; Jingyu Yao; Lin Jia; Steven F. Abcouwer; David N. Zacks

Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):39. https://doi.org/10.1167/iovs.65.11.39

Includes: Supplemental Content

Low Vision Rehabilitation September 2024

Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT)–Optimizing Stimulation Protocol for Vision Enhancement Using an RCT

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Xiaolin Mei; LaiLin Tsang; Theodore Jacques; Bernhard A. Sabel; Christopher Kai Shun Leung; Jonathan Cheuk Hung Chan; Benjamin Thompson; Allen Ming Yan Cheong
TAGS: glaucoma, rehabilitation, transanal endoscopic surgery, vision, visual fields, transcranial direct current stimulation
Trans. Vis. Sci. Tech.. 2024; 13(9):25. https://doi.org/10.1167/tvst.13.9.25

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Crossing category boundaries: Perceptual hysteresis for scenes even with endpoint preview

Huiqin Chen; Mei Yang; Gaeun Son; Dirk Bernhardt-Walther

Journal of Vision. 2024; 24(10):555. https://doi.org/10.1167/jov.24.10.555

Vision Sciences Society Annual Meeting Abstract September 2024

Bridging perspectives: a foundational dataset for the empirical aesthetics of bridge design

Mei Yang; Claudia Damiano; Paul Gauvreau; Dirk B. Walther

Journal of Vision. 2024; 24(10):1070. https://doi.org/10.1167/jov.24.10.1070

Artificial Intelligence September 2024

Beyond PhacoTrainer: Deep Learning for Enhanced Trabecular Meshwork Detection in MIGS Videos

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Su Kara; Michael Yang; Hsu-Hang Yeh; Simmi Sen; Hannah H. Hwang; Sophia Y. Wang
TAGS: deep learning, learning, surgical procedures, operative, trabecular meshwork, transfer technique, cataract, training
Trans. Vis. Sci. Tech.. 2024; 13(9):5. https://doi.org/10.1167/tvst.13.9.5

Includes: Multimedia, Supplemental Content

Retinal Cell Biology August 2024

Pigment Epithelium-Derived Factor Binding to VEGFR-1 (Flt-1) Increases the Survival of Retinal Neurons

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Jie Meng; Xiu Mei Yang; Oliver Scheer; Johannes Lange; Heidi Müller; Susanne Bürger; Sven Rothemund; Ruaa Younis; Jan D. Unterlauft; Wolfram Eichler
TAGS: vegfr-1, vascular endothelial growth factor receptors, retinal neurons, pigment, placenta growth factor, vascular endothelial growth factor a, epithelium
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):27. https://doi.org/10.1167/iovs.65.10.27

Includes: Supplemental Content

ARVO Imaging in the Eye Conference Abstract July 2024

Longitudinal Molecular Visualization of Choroidal Neovascularization Using Multimodal Photoacoustic Microscopy, OCT, and Fluorescence Imaging

Phuc Nguyen; Wei Qian; Bing Liu; Josh Zhe; Mingyang Wang; Wei Zhang; Xueding Wang; Yannis M. Paulus

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PP003.

ARVO Imaging in the Eye Conference Abstract July 2024

Organic Phosphorescent Nanosensors to Quantify Retinal Hypoxia in Retinal Vascular Occlusion

Yannis Mantas Paulus; Phuc Nguyen; Jungmoo Heo; Jinsang Kim

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PP004.

Glaucoma July 2024

Differences in Systemic Pulse Waveform Between Individuals With Glaucoma, Glaucoma Suspects, and Healthy Controls

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Hongli Yang; Grant Cull; Mingrui Yang; Lin Wang; Brad Fortune; Stuart K. Gardiner
TAGS: glaucoma, pulse waveform, waveforms, global longitudinal strain, blood pressure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):20. https://doi.org/10.1167/iovs.65.8.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

A novel function of optineurin in axonal mitochondria transport for axon integrity and regeneration

Yang Hu; Dong Liu; Hannah Webber; Fuyun Bian; Manjari Prakash; Liang Li; In Jee You; Xue Feng; Hang Yang; Liping Liu; Pingting Liu; Ming Yang; Haoliang Huang; Zdenek Lansky

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):944.

ARVO Annual Meeting Abstract June 2024

Microcurrent electrical stimulation restores corneal nerve density in diabetic keratopathy by promoting axon growth in trigeminal ganglia neurons

Menglu Yang; Anton Lennikov; Farris ElZaridi; Darlene A Dartt; Dongfeng Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6501.

ARVO Annual Meeting Abstract June 2024

Glaucoma Medication Persistence Rates in Ontario – A Retrospective Population-Based Study

Tianwei Ellen Zhou; Jimmy Hu; Mike Yang; Marko Popovic; Laura Rosella; Matthew Brian Schlenker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4628.

ARVO Annual Meeting Abstract June 2024

Systemic pulse waveform parameters associated with vascular stiffness can predict the rate of functional progression in glaucoma and glaucoma suspects

Hongli Yang; Grant Cull; Mingrui Yang; Steven L Mansberger; Brad Fortune; Stuart Keith Gardiner

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4789.

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The Exponential Constriction Model of the Ellipsoid Zone in Taiwanese Individuals With RPGR-Related X-Linked Retinitis Pigmentosa

Remote Preconditioning Provides Protection Against Retinal Cell Death From Retinal Detachment

Elevated Very-Long-Chain Ceramides in the Vitreous Humor of Patients With Proliferative Diabetic Retinopathy

ROCK Inhibitor Enhances Resilience Against Metabolic Stress Through Increasing Bioenergetic Capacity in Corneal Endothelial Cells

Pyrimidinergic P2Y1-Like Nucleotide Receptors Are Functional in Rat Conjunctival Goblet Cells

The Short- and Long-Term Perceptual Learning of Clinical Dynamic Visual Acuity Test

Mesenchymal Stem Cells-Derived Exosomal miR-223-3p Alleviates Ocular Surface Damage and Inflammation by Downregulating Fbxw7 in Dry Eye Models

ER Stress and Mitochondrial Perturbations Regulate Cell Death in Retinal Detachment: Exploring the Role of HIF1α

Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT)–Optimizing Stimulation Protocol for Vision Enhancement Using an RCT

Crossing category boundaries: Perceptual hysteresis for scenes even with endpoint preview

Bridging perspectives: a foundational dataset for the empirical aesthetics of bridge design

Beyond PhacoTrainer: Deep Learning for Enhanced Trabecular Meshwork Detection in MIGS Videos

Pigment Epithelium-Derived Factor Binding to VEGFR-1 (Flt-1) Increases the Survival of Retinal Neurons

Longitudinal Molecular Visualization of Choroidal Neovascularization Using Multimodal Photoacoustic Microscopy, OCT, and Fluorescence Imaging

Organic Phosphorescent Nanosensors to Quantify Retinal Hypoxia in Retinal Vascular Occlusion

Differences in Systemic Pulse Waveform Between Individuals With Glaucoma, Glaucoma Suspects, and Healthy Controls

A novel function of optineurin in axonal mitochondria transport for axon integrity and regeneration

Microcurrent electrical stimulation restores corneal nerve density in diabetic keratopathy by promoting axon growth in trigeminal ganglia neurons

Glaucoma Medication Persistence Rates in Ontario – A Retrospective Population-Based Study

Systemic pulse waveform parameters associated with vascular stiffness can predict the rate of functional progression in glaucoma and glaucoma suspects

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