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ARVO Annual Meeting Abstract June 2024

Propranolol demonstrates antifungal activity against Fusarium and Apergillus corneal isolates and in a murine model of fungal keratitis.

Michael E Zegans; Kevin K Fuller; Cecilia Gutierrez-Perez; Chetan Pavuluri; Ruina Bao; Brandon Ross; Galini Poimenidou; N Venkatesh Prajna; K Dharmalingam; Robert Cramer

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1963.

ARVO Annual Meeting Abstract June 2024

Cefiderocol is an effective topical monotherapy for experimental extensively-drug resistant Pseudomonas aeruginosa keratitis.

Eric G Romanowski; Sonya M Mumper; Hazel Q Shanks; Kathleen A Yates; Jonathan B Mandell; Michael E Zegans; Robert M Q Shanks

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2095.

ARVO Annual Meeting Abstract June 2024

Genetic basis, antibiotic susceptibility, and clinical outcomes of lasR mutant Pseudomonas aeruginosa keratitis isolates

Vishal Jhanji; Sarah Atta; Chollapadi Sundar-Raj; John Romanowski; Arman Grewal; Hazel Shanks; Sonya M Mumper; Alex Mammen; Deepinder K. Dhaliwal; Rachel Calvario; Eric G Romanowski; Michael E Zegans; Robert M Q Shanks

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3686.

ARVO Annual Meeting Abstract June 2020

Increasing frequency of sheen isolates detected among Pseudomonas aeruginosa keratitis isolates over the past 20 years

Cholappadi V Sundar-Raj; Hazel Q Shanks; John E Romanowski; Michael E Zegans; Regis P Kowalski; Robert M Q Shanks

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4888.

ARVO Annual Meeting Abstract July 2019

Understanding fungal keratitis pathogenesis through a reverse-translational approach.

Kevin K Fuller; Marina Evette Brown; David Giacalone; Jay Dunlap; Tom Lietman; Robert Cramer; K Dharmalingam; Michael Zegans

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):865.

ARVO Annual Meeting Abstract June 2017

Trends of intravenous drug use associated endogenous endophthalmitis at a tertiary care center

Preston Mackenzie Luong; Edmund Tsui; Nikhil Batra; Michael E Zegans

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5504.

ARVO Annual Meeting Abstract June 2015

Effect of pretreatment with antifungals on clinical outcomes in the Mycotic Ulcer Treatment Trial I

Catherine Sun; Namperumalsamy Venkatesh Prajna; Lalitha Prajna; Muthiah Srinivasan; Michael E Zegans; Stephen D McLeod; Nisha Acharya; Thomas M Lietman; Jennifer Rose-Nussbaumer; Mycotic Ulcer Treatment Trial Group

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1882.

ARVO Annual Meeting Abstract June 2015

Pseudomonas aeruginosa isolates with lasR mutations were associated with worse visual outcomes in the Steroids For Corneal Ulcer Trial (SCUT)

Michael E Zegans; Kathryn Ray; Wesley Hebert; Amanda Naimie; John H Hammond; Lalitha Prajna; Deborah Hogan; Antonio DiGiandomenico; Thomas M Lietman; Muthiah Srinivasan; Steroids for Corneal Ulcers Trial Study Group

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4847.

Clinical Trials January 2012

Pseudomonas aeruginosa Keratitis: Outcomes and Response to Corticosteroid Treatment

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Aileen Sy; Muthiah Srinivasan; Jeena Mascarenhas; Prajna Lalitha; Revathi Rajaraman; Meenakshi Ravindran; Catherine E. Oldenburg; Kathryn J. Ray; David Glidden; Michael E. Zegans; Stephen D. McLeod; Thomas M. Lietman; Nisha R. Acharya
TAGS: adrenal corticosteroids, glucocorticoids, keratitis, mineralocorticoids, pseudomonas aeruginosa, ulcer, placebos, cicatrix
Invest. Ophthalmol. Vis. Sci.. 2012; 53(1):267-272. https://doi.org/10.1167/iovs.11-7840

ARVO Annual Meeting Abstract April 2011

Diphosphonium Ionic Liquids as a Novel Broad Spectrum Antimicrobial Agents and Their In vivo Use to Prevent Pseudomonas Keratitis

Michael E. Zegans; George A. O'Toole; Michel Wathier; Robert M. Shanks; Regis Kowalski; Mark Grinstaff

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4763.

ARVO Annual Meeting Abstract April 2011

Clinical Differentiation of Organisms in Bacterial Keratitis

Michael C. Chen; Catherine E. Oldenburg; Muthiah Srinivasan; Jeena Mascarenhas; Prajna Lalitha; Kathryn J. Ray; Michael E. Zegans; Stephen D. McLeod; Nisha R. Acharya; Thomas M. Lietman

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5848.

ARVO Annual Meeting Abstract April 2011

An Association between Killer Cell Immunoglobulin-like Receptor (KIR) Genes and Toxoplasmic Retinochoroiditis

David C. Reed; Gary N. Holland; Patrick A. Coady; Ralph D. Levinson; Michael E. Zegans; Tiago E. Arantes; Jose G. Montoya; Ying Qian; Raj Rajalingam; North American Ocular Toxoplasmosis Research Group

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2396.

ARVO Annual Meeting Abstract April 2010

Alteration of Lipopolysaccharide Biosynthesis Impacts Polysorbate 80 Mediated Biofilm Inhibition of Pseudomonas aeruginosa

M. E. Zegans; J. Lam; C. Toutain-Kidd; J. H. Hammond

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):3900.

ARVO Annual Meeting Abstract April 2009

Inhibition of Biofilm Formation of Pseudomonas aeruginosa by Polysorbate 80: A role of the Secretin, XcpQ

C. M. Toutain-Kidd; M. E. Zegans

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):3104.

ARVO Annual Meeting Abstract May 2008

Bacteriophage DMS3 Inhibits Biofilm Formation and Swarming of Pseudomonas aeruginosa in a CRISPR Dependent Manner

M. E. Zegans; K. C. Cady; J. Wagner; J. H. Hammond; D. Murphy; R. T. Allar; A. A. Borquez; G. A. O'Toole

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4486.

ARVO Annual Meeting Abstract May 2007

Inhibition of Pseudomonas Aeruginosa Biofilm Formation by Polysorbate 80, a Common Additive to Eye Drops

M. E. Zegans; C. T. Bramante; C. M. Toutain

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):5986.

ARVO Annual Meeting Abstract May 2006

Steroids for Corneal Ulcers Treatment – SCUT Pilot Study Results

N. Acharya; M. Srinivasan; R. Mahalakshmi; D. Jayashree; L. Prajna; J. House; S. Mcleod; J. Whitcher; M. Zegans; T. Lietman

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):4752.

ARVO Annual Meeting Abstract May 2006

Analysis of Digital Images of Corneal Ulcers in the Pilot Study for the Steroid Corneal Ulcer Trial (SCUT)

M.E. Zegans; C. Toutain; P. Saine; M. Srinivasan; D. Jayashree; R. Mahalakshmi; V. Moorthy; V. Akki; T. Lietman

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):1885.

ARVO Annual Meeting Abstract May 2005

Characteristics of Mooren's Ulcer in Surgical vs. Non–Surgical Patients

N. Acharya; M. Srinivasan; M. Zegans; T. Magone; T. Lietman; E. Cunningham; J. Whitcher

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):5008.

ARVO Annual Meeting Abstract May 2004

A mutant of Pseudomonas aeruginosa PA14 defective in biofilm formation and corneal virulence.

M.E. Zegans; C.M. Toutain; G.A. O'Toole

Invest. Ophthalmol. Vis. Sci.. 2004; 45(13):4637.

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Propranolol demonstrates antifungal activity against Fusarium and Apergillus corneal isolates and in a murine model of fungal keratitis.

Cefiderocol is an effective topical monotherapy for experimental extensively-drug resistant Pseudomonas aeruginosa keratitis.

Genetic basis, antibiotic susceptibility, and clinical outcomes of lasR mutant Pseudomonas aeruginosa keratitis isolates

Increasing frequency of sheen isolates detected among Pseudomonas aeruginosa keratitis isolates over the past 20 years

Understanding fungal keratitis pathogenesis through a reverse-translational approach.

Trends of intravenous drug use associated endogenous endophthalmitis at a tertiary care center

Effect of pretreatment with antifungals on clinical outcomes in the Mycotic Ulcer Treatment Trial I

Pseudomonas aeruginosa isolates with lasR mutations were associated with worse visual outcomes in the Steroids For Corneal Ulcer Trial (SCUT)

Pseudomonas aeruginosa Keratitis: Outcomes and Response to Corticosteroid Treatment

Diphosphonium Ionic Liquids as a Novel Broad Spectrum Antimicrobial Agents and Their In vivo Use to Prevent Pseudomonas Keratitis

Clinical Differentiation of Organisms in Bacterial Keratitis

An Association between Killer Cell Immunoglobulin-like Receptor (KIR) Genes and Toxoplasmic Retinochoroiditis

Alteration of Lipopolysaccharide Biosynthesis Impacts Polysorbate 80 Mediated Biofilm Inhibition of Pseudomonas aeruginosa

Inhibition of Biofilm Formation of Pseudomonas aeruginosa by Polysorbate 80: A role of the Secretin, XcpQ

Bacteriophage DMS3 Inhibits Biofilm Formation and Swarming of Pseudomonas aeruginosa in a CRISPR Dependent Manner

Inhibition of Pseudomonas Aeruginosa Biofilm Formation by Polysorbate 80, a Common Additive to Eye Drops

Steroids for Corneal Ulcers Treatment – SCUT Pilot Study Results

Analysis of Digital Images of Corneal Ulcers in the Pilot Study for the Steroid Corneal Ulcer Trial (SCUT)

Characteristics of Mooren's Ulcer in Surgical vs. Non–Surgical Patients

A mutant of Pseudomonas aeruginosa PA14 defective in biofilm formation and corneal virulence.

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