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Anatomy and Pathology/Oncology June 2025

Studies of All- trans Retinoic Acid Transport in the Eye

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Saptarshi Chatterjee; Ankana Roy; Jianshi Yu; Arthur Thomas Read; Melissa R. Bentley-Ford; Machelle T. Pardue; Maureen A. Kane; M. G. Finn; C. Ross Ethier
TAGS: tretinoin, proteins, fluorescence
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):84. https://doi.org/10.1167/iovs.66.6.84

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2025

All-trans retinoic acid (atRA) transport in myopigenesis

Mariia Dvoriashyna; Melissa Bentley-Ford; Jianshi Yu; Machelle T Pardue; Maureen A Kane; Rodolfo Repetto; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4563.

ARVO Annual Meeting Abstract June 2025

Deep-Learning segmentation of the Retina, Choroid, and Sclera from Mice OCT Scans

Gabriela Sanchez; Linjiang Lou; Machelle T Pardue; Andrew J. Feola

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1731.

ARVO Annual Meeting Abstract June 2025

Sustained benefit of acute levodopa treatment on ERG oscillatory potentials in early diabetic retinopathy (DR)

Dane Rubenstein; Stephen Philips; Francesca Moore; Caleigh Cullinan; Christina Young; Andrew J. Feola; Risha Patel; Mary Rhee; Hendrick Andrew; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5585.

ARVO Annual Meeting Abstract June 2025

LDOPA treatment provides functional neurovascular benefit in diabetic mice with dose-sensitive sustained effect

Eli Chlan; Harish Kalyan; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4838.

ARVO Annual Meeting Abstract June 2025

Effect of violet light supplementation on mouse refractive development

Shruti Balamurugan; Teele Palumaa; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4559.

ARVO Annual Meeting Abstract June 2025

Validation and Characterization of Refractive Development in a Novel Gnat2 Knockout Mouse Allele

Linjiang Lou; Melissa Bentley-Ford; Micah A Chrenek; Ramnath Saminath Gandhi; Teele Palumaa; Elena Demers; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4542.

ARVO Annual Meeting Abstract June 2025

Techniques for studying all- trans retinoic acid (atRA) transport in myopigenesis

C Ross Ethier; Saptarshi Chatterjee; Ankana Roy; Jianshi Yu; A. Thomas Read; Melissa Bentley-Ford; Machelle T Pardue; Maureen A Kane; M.G. Finn

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2835.

ARVO Annual Meeting Abstract June 2025

Influence of text contrast on axial length in virtual reality, establishing a benchmark for myopia studies

Santiago Arconada Alvarez; Linjiang Lou; Ramnath Saminath Gandhi; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2115.

ARVO Annual Meeting Abstract June 2025

Extended environmental light-dark cycle induces myopic changes in adult mice with implications of cholinergic and GABAergic pathways

Teele Palumaa; Shruti Balamurugan; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):947.

ARVO Annual Meeting Abstract June 2025

Treadmill exercise protects retinal vascular integrity and alters circulating immune factors in mice undergoing light-induced retinal degeneration

Katie Bales; Hayden Haupt; John M Nickerson; Jeffrey H Boatright; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1254.

ARVO Annual Meeting Abstract June 2025

Exercise-induced TrkB signaling preserves retinal vascular function and morphology in light-induced retinal degeneration

Connor Douglas Malloch; Hayden Haupt; Jackson A Banks; Teresa E Anderson; Andrew J. Feola; Jeffrey H Boatright; Machelle T Pardue; Katie Bales

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1243.

ARVO Annual Meeting Abstract June 2025

Topical 2-amino-4-phosphonobutyrate (APB) as a Tool to Modulate ON-pathways

Morgan L Bade; Reece Mazade; Machelle T Pardue; Ming-fai Fong

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2323.

ARVO Annual Meeting Abstract June 2025

Long-term effects of acute levodopa treatment on retinal thickness in preclinical diabetic retinopathy

Francesca Moore; Stephen Phillips; Dane Rubenstein; Caleigh Cullinan; Christina Young; Andrew J. Feola; Risha Patel; Mary Rhee; Hendrick Andrew; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2802.

Visual Neuroscience March 2025

Modulation of All- Trans Retinoic Acid by Light and Dopamine in the Murine Eye

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Sarah Talwar; Reece Mazade; Melissa Bentley-Ford; Jianshi Yu; Nageswara Pilli; Maureen A. Kane; C. Ross Ethier; Machelle T. Pardue
TAGS: eye, mice, tretinoin, retinoids, lighting, dopamine, light exposure
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):37. https://doi.org/10.1167/iovs.66.3.37

Artificial Intelligence February 2025

RetOCTNet: Deep Learning–Based Segmentation of OCT Images Following Retinal Ganglion Cell Injury

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Gabriela Sanchez-Rodriguez; Linjiang Lou; Machelle T. Pardue; Andrew J. Feola
TAGS: datasets, deep learning, retinal ganglion cells, wounds and injuries, retinal nerve fiber layer, optic disk, eye, training
Trans. Vis. Sci. Tech.. 2025; 14(2):4. https://doi.org/10.1167/tvst.14.2.4

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

LDOPA provides sustained visual function benefit in diabetic mice following treatment cessation

Eli Chlan; Nikita Savant; Ashley Prichard; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):310.

ARVO Annual Meeting Abstract June 2024

Treadmill exercise maintains retinal vascular morphology and function and alters gene expression in a light-induced retinal degeneration mouse model

Hayden Haupt; John M Nickerson; Jeffrey H Boatright; Machelle T Pardue; Katie Bales

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1330.

ARVO Annual Meeting Abstract June 2024

Treadmill exercise decreases recruitment of retinal inflammatory cells, alters retinal miRNA expression profiles and protects against retinal degeneration.

Katie Bales; Hayden Haupt; Teele Palumaa; Gabriela Sanchez; Andrew J. Feola; Joshua Chu-Tan; Riccardo Natoli; John M Nickerson; Machelle T Pardue; Jeffrey H Boatright

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1267.

ARVO Annual Meeting Abstract June 2024

Effects of light exposure and dopamine on all-trans retinoic acid in the murine eye

Sarah Talwar; Reece Mazade; Jianshi Yu; Nageswara Pilli; Maureen A. Kane; C Ross Ethier; Machelle T Pardue

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1166.

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Studies of All- trans Retinoic Acid Transport in the Eye

All-trans retinoic acid (atRA) transport in myopigenesis

Deep-Learning segmentation of the Retina, Choroid, and Sclera from Mice OCT Scans

Sustained benefit of acute levodopa treatment on ERG oscillatory potentials in early diabetic retinopathy (DR)

LDOPA treatment provides functional neurovascular benefit in diabetic mice with dose-sensitive sustained effect

Effect of violet light supplementation on mouse refractive development

Validation and Characterization of Refractive Development in a Novel Gnat2 Knockout Mouse Allele

Techniques for studying all- trans retinoic acid (atRA) transport in myopigenesis

Influence of text contrast on axial length in virtual reality, establishing a benchmark for myopia studies

Extended environmental light-dark cycle induces myopic changes in adult mice with implications of cholinergic and GABAergic pathways

Treadmill exercise protects retinal vascular integrity and alters circulating immune factors in mice undergoing light-induced retinal degeneration

Exercise-induced TrkB signaling preserves retinal vascular function and morphology in light-induced retinal degeneration

Topical 2-amino-4-phosphonobutyrate (APB) as a Tool to Modulate ON-pathways

Long-term effects of acute levodopa treatment on retinal thickness in preclinical diabetic retinopathy

Modulation of All- Trans Retinoic Acid by Light and Dopamine in the Murine Eye

RetOCTNet: Deep Learning–Based Segmentation of OCT Images Following Retinal Ganglion Cell Injury

LDOPA provides sustained visual function benefit in diabetic mice following treatment cessation

Treadmill exercise maintains retinal vascular morphology and function and alters gene expression in a light-induced retinal degeneration mouse model

Treadmill exercise decreases recruitment of retinal inflammatory cells, alters retinal miRNA expression profiles and protects against retinal degeneration.

Effects of light exposure and dopamine on all-trans retinoic acid in the murine eye

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