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ARVO Annual Meeting Abstract June 2020

Metabolic alterations during TGFβ2-induced EMT in retinal pigment epithelial (RPE) cells

Daisy Yao Shu; Erik Butcher; Siwei Cai; Ilakya Senthilkumar; Scott Frank; Kiran Kurmi; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3181. doi:

ARVO Annual Meeting Abstract June 2020

Identification of PGC-1β as novel stress response target in neovascular AMD

Siwei Cai; Daisy Yao Shu; Erik Butcher; Ilakya Senthilkumar; Scott Frank; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3537. doi:

ARVO Annual Meeting Abstract June 2020

Anti-angiogenic effects of a novel small molecular activator of PGC-1α

Magali Saint-Geniez; Ilakya Senthilkumar; Siwei Cai; Daisy Yao Shu; Erik Butcher; Scott Frank

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4341. doi:

ARVO Annual Meeting Abstract July 2019

Metabolic normalization protects RPE against TGFβ-induced epithelial-to-mesenchymal transition

Magali Saint-Geniez; Sangeeta Satish; Hannah Philipose; Mariana Aparecida Rosales

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4412. doi:

ARVO Annual Meeting Abstract July 2019

Endomucin regulates Vascular Endothelial Growth Factor (VEGF) induced endothelium functions through its extracellular domain

Zhengping Hu; Michelle LeBlanc; kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Patricia A. D'Amore

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5376. doi:

ARVO Annual Meeting Abstract July 2019

Endomucin and galectin-3 modulate VEGFR2-mediated endothelial functions

Michelle LeBlanc; Issahy Cano; Zhengping Hu; kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Pablo Argueso; Patricia A. D'Amore

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3259. doi:

ARVO Annual Meeting Abstract July 2018

Loss of PGC-1α function in RPE induces EMT and promotes retinal degeneration

Mariana Aparecida Rosales; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1185. doi:

ARVO Annual Meeting Abstract July 2018

Endomucin (EMCN) Regulates Angiogenesis by Controlling VEGFR2 Endocytosis

Michelle LeBlanc; Kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5481. doi:

ARVO Annual Meeting Abstract July 2018

Pharmaceutical induction of PGC-1α protects retinal pigment epithelium from oxidative stress

Magali Saint-Geniez; Sangeeta Satish; Hannah Philipose; Mariana Aparecida Rosales

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2476. doi:

ARVO Annual Meeting Abstract June 2017

Endomucin depletion inhibits pathologic retinal vascularization in vivo

Patricia A D'Amore; Cindy Park-Windhol; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4058. doi:

ARVO Annual Meeting Abstract June 2017

PGC-1beta promotes oxidative damage and dysfunction of the retinal pigment epithelium

Magali Saint-Geniez; Quincy Charles; Mariana Rosales; Arogya Khadka; Gopalan Gnanaguru; Jared Iacovelli

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3381. doi:

ARVO Annual Meeting Abstract June 2017

PGC-1α is required to maintain RPE metabolism, integrity and function.

Mariana Aparecida Brunini Rosales; Sarah Melissa Jacobo; Jared Iacovelli; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3014. doi:

ARVO Annual Meeting Abstract September 2016

Feedback Regulation of IRE1 During Unfolded Protein Response in RPE

Sarah Melissa P. Jacobo; Maximilian J Gerhardt; arogya Khadka; Daniel Diaz-Aguilar; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):254. doi:

ARVO Annual Meeting Abstract September 2016

Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by suppressing VEGFR2 signaling

Patricia A D'Amore; Cindy Park-Windhol; Yin Shan Eric Ng; Jinling Yang; Vincent Primo; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3637. doi:

ARVO Annual Meeting Abstract September 2016

Characterization of Mitochondrial and Metabolic Changes Following Retinal Detachment

Daniel Diaz-Aguilar; Zhaohui Li; Yoko Okunuki; arogya Khadka; Sarah Melissa P. Jacobo; Kip M Connor; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Retinal Cell Biology March 2016

PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity

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Jared Iacovelli; Glenn C. Rowe; Arogya Khadka; Daniel Diaz-Aguilar; Carrie Spencer; Zoltan Arany; Magali Saint-Geniez
TAGS: antioxidants, cell respiration, gene expression, metabolism, proteins, oxidants, cell death, mitochondria, fatty acids, genes
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):1038-1051. doi: https://doi.org/10.1167/iovs.15-17758

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Endomucin Plays a Role in Developmental Retinal Vascularization and in VEGF-Induced Endothelial Cell Migration, Growth, and Morphogenesis In Vitro

Cindy Park-Windhol; Jinling Yang; Vincent Primo; Yin Shan Eric Ng; Magali Saint-Geniez; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3404. doi:

ARVO Annual Meeting Abstract June 2015

Control of human RPE differentiation and metabolism by PGC-1α: implications for AMD

Magali Saint-Geniez; Jared Iacovelli; Glenn Rowe; Zoltan Arany

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):830. doi:

ARVO Annual Meeting Abstract June 2015

Shedding of Endomucin by Endothelial Cells under Inflammatory Conditions: Involvement of Matrix Metalloproteases

Jinling Yang; Magali Saint-Geniez; Yin Shan Eric Ng; Marsha A. Moses; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3104. doi:

ARVO Annual Meeting Abstract April 2014

PGC-1 alpha regulates human RPE oxidative metabolism and anti-oxidant capacity

Jared Iacovelli; Glenn C Rowe; Zoltan Arany; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1740. doi:

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Metabolic alterations during TGFβ2-induced EMT in retinal pigment epithelial (RPE) cells

Identification of PGC-1β as novel stress response target in neovascular AMD

Anti-angiogenic effects of a novel small molecular activator of PGC-1α

Metabolic normalization protects RPE against TGFβ-induced epithelial-to-mesenchymal transition

Endomucin regulates Vascular Endothelial Growth Factor (VEGF) induced endothelium functions through its extracellular domain

Endomucin and galectin-3 modulate VEGFR2-mediated endothelial functions

Loss of PGC-1α function in RPE induces EMT and promotes retinal degeneration

Endomucin (EMCN) Regulates Angiogenesis by Controlling VEGFR2 Endocytosis

Pharmaceutical induction of PGC-1α protects retinal pigment epithelium from oxidative stress

Endomucin depletion inhibits pathologic retinal vascularization in vivo

PGC-1beta promotes oxidative damage and dysfunction of the retinal pigment epithelium

PGC-1α is required to maintain RPE metabolism, integrity and function.

Feedback Regulation of IRE1 During Unfolded Protein Response in RPE

Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by suppressing VEGFR2 signaling

Characterization of Mitochondrial and Metabolic Changes Following Retinal Detachment

PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity

Endomucin Plays a Role in Developmental Retinal Vascularization and in VEGF-Induced Endothelial Cell Migration, Growth, and Morphogenesis In Vitro

Control of human RPE differentiation and metabolism by PGC-1α: implications for AMD

Shedding of Endomucin by Endothelial Cells under Inflammatory Conditions: Involvement of Matrix Metalloproteases

PGC-1 alpha regulates human RPE oxidative metabolism and anti-oxidant capacity

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