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ARVO Annual Meeting Abstract June 2020

Metabolic alterations during TGFβ2-induced EMT in retinal pigment epithelial (RPE) cells

Daisy Yao Shu; Erik Butcher; Siwei Cai; Ilakya Senthilkumar; Scott Frank; Kiran Kurmi; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3181. doi:

ARVO Annual Meeting Abstract June 2020

Identification of PGC-1β as novel stress response target in neovascular AMD

Siwei Cai; Daisy Yao Shu; Erik Butcher; Ilakya Senthilkumar; Scott Frank; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3537. doi:

ARVO Annual Meeting Abstract June 2020

Anti-angiogenic effects of a novel small molecular activator of PGC-1α

Magali Saint-Geniez; Ilakya Senthilkumar; Siwei Cai; Daisy Yao Shu; Erik Butcher; Scott Frank

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4341. doi:

ARVO Annual Meeting Abstract July 2019

Endomucin and galectin-3 modulate VEGFR2-mediated endothelial functions

Michelle LeBlanc; Issahy Cano; Zhengping Hu; kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Pablo Argueso; Patricia A. D'Amore

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3259. doi:

ARVO Annual Meeting Abstract July 2019

Metabolic normalization protects RPE against TGFβ-induced epithelial-to-mesenchymal transition

Magali Saint-Geniez; Sangeeta Satish; Hannah Philipose; Mariana Aparecida Rosales

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4412. doi:

ARVO Annual Meeting Abstract July 2019

Endomucin regulates Vascular Endothelial Growth Factor (VEGF) induced endothelium functions through its extracellular domain

Zhengping Hu; Michelle LeBlanc; kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Patricia A. D'Amore

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5376. doi:

ARVO Annual Meeting Abstract July 2018

Endomucin (EMCN) Regulates Angiogenesis by Controlling VEGFR2 Endocytosis

Michelle LeBlanc; Kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5481. doi:

ARVO Annual Meeting Abstract July 2018

Loss of PGC-1α function in RPE induces EMT and promotes retinal degeneration

Mariana Aparecida Rosales; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1185. doi:

ARVO Annual Meeting Abstract July 2018

Pharmaceutical induction of PGC-1α protects retinal pigment epithelium from oxidative stress

Magali Saint-Geniez; Sangeeta Satish; Hannah Philipose; Mariana Aparecida Rosales

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2476. doi:

ARVO Annual Meeting Abstract June 2017

PGC-1α is required to maintain RPE metabolism, integrity and function.

Mariana Aparecida Brunini Rosales; Sarah Melissa Jacobo; Jared Iacovelli; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3014. doi:

ARVO Annual Meeting Abstract June 2017

PGC-1beta promotes oxidative damage and dysfunction of the retinal pigment epithelium

Magali Saint-Geniez; Quincy Charles; Mariana Rosales; Arogya Khadka; Gopalan Gnanaguru; Jared Iacovelli

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3381. doi:

ARVO Annual Meeting Abstract June 2017

Endomucin depletion inhibits pathologic retinal vascularization in vivo

Patricia A D'Amore; Cindy Park-Windhol; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4058. doi:

ARVO Annual Meeting Abstract September 2016

Feedback Regulation of IRE1 During Unfolded Protein Response in RPE

Sarah Melissa P. Jacobo; Maximilian J Gerhardt; arogya Khadka; Daniel Diaz-Aguilar; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):254. doi:

ARVO Annual Meeting Abstract September 2016

Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by suppressing VEGFR2 signaling

Patricia A D'Amore; Cindy Park-Windhol; Yin Shan Eric Ng; Jinling Yang; Vincent Primo; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3637. doi:

ARVO Annual Meeting Abstract September 2016

Characterization of Mitochondrial and Metabolic Changes Following Retinal Detachment

Daniel Diaz-Aguilar; Zhaohui Li; Yoko Okunuki; arogya Khadka; Sarah Melissa P. Jacobo; Kip M Connor; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Retinal Cell Biology March 2016

PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity

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Jared Iacovelli; Glenn C. Rowe; Arogya Khadka; Daniel Diaz-Aguilar; Carrie Spencer; Zoltan Arany; Magali Saint-Geniez
TAGS: antioxidants, cell respiration, gene expression, metabolism, proteins, oxidants, cell death, mitochondria, fatty acids, genes
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):1038-1051. doi: https://doi.org/10.1167/iovs.15-17758

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Shedding of Endomucin by Endothelial Cells under Inflammatory Conditions: Involvement of Matrix Metalloproteases

Jinling Yang; Magali Saint-Geniez; Yin Shan Eric Ng; Marsha A. Moses; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3104. doi:

ARVO Annual Meeting Abstract June 2015

Endomucin Plays a Role in Developmental Retinal Vascularization and in VEGF-Induced Endothelial Cell Migration, Growth, and Morphogenesis In Vitro

Cindy Park-Windhol; Jinling Yang; Vincent Primo; Yin Shan Eric Ng; Magali Saint-Geniez; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3404. doi:

ARVO Annual Meeting Abstract June 2015

Control of human RPE differentiation and metabolism by PGC-1α: implications for AMD

Magali Saint-Geniez; Jared Iacovelli; Glenn Rowe; Zoltan Arany

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):830. doi:

ARVO Annual Meeting Abstract April 2014

PGC-1 alpha regulates human RPE oxidative metabolism and anti-oxidant capacity

Jared Iacovelli; Glenn C Rowe; Zoltan Arany; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1740. doi:

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Metabolic alterations during TGFβ2-induced EMT in retinal pigment epithelial (RPE) cells

Identification of PGC-1β as novel stress response target in neovascular AMD

Anti-angiogenic effects of a novel small molecular activator of PGC-1α

Endomucin and galectin-3 modulate VEGFR2-mediated endothelial functions

Metabolic normalization protects RPE against TGFβ-induced epithelial-to-mesenchymal transition

Endomucin regulates Vascular Endothelial Growth Factor (VEGF) induced endothelium functions through its extracellular domain

Endomucin (EMCN) Regulates Angiogenesis by Controlling VEGFR2 Endocytosis

Loss of PGC-1α function in RPE induces EMT and promotes retinal degeneration

Pharmaceutical induction of PGC-1α protects retinal pigment epithelium from oxidative stress

PGC-1α is required to maintain RPE metabolism, integrity and function.

PGC-1beta promotes oxidative damage and dysfunction of the retinal pigment epithelium

Endomucin depletion inhibits pathologic retinal vascularization in vivo

Feedback Regulation of IRE1 During Unfolded Protein Response in RPE

Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by suppressing VEGFR2 signaling

Characterization of Mitochondrial and Metabolic Changes Following Retinal Detachment

PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity

Shedding of Endomucin by Endothelial Cells under Inflammatory Conditions: Involvement of Matrix Metalloproteases

Endomucin Plays a Role in Developmental Retinal Vascularization and in VEGF-Induced Endothelial Cell Migration, Growth, and Morphogenesis In Vitro

Control of human RPE differentiation and metabolism by PGC-1α: implications for AMD

PGC-1 alpha regulates human RPE oxidative metabolism and anti-oxidant capacity

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