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ARVO Annual Meeting Abstract July 2018

Loss of PGC-1α function in RPE induces EMT and promotes retinal degeneration

Mariana Aparecida Rosales; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1185. doi:

ARVO Annual Meeting Abstract July 2018

Pharmaceutical induction of PGC-1α protects retinal pigment epithelium from oxidative stress

Magali Saint-Geniez; Sangeeta Satish; Hannah Philipose; Mariana Aparecida Rosales

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2476. doi:

ARVO Annual Meeting Abstract July 2018

Endomucin (EMCN) Regulates Angiogenesis by Controlling VEGFR2 Endocytosis

Michelle LeBlanc; Kahira Saez-Torres; Magali Saint-Geniez; Yin Shan Eric Ng; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5481. doi:

ARVO Annual Meeting Abstract June 2017

PGC-1α is required to maintain RPE metabolism, integrity and function.

Mariana Aparecida Brunini Rosales; Sarah Melissa Jacobo; Jared Iacovelli; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3014. doi:

ARVO Annual Meeting Abstract June 2017

PGC-1beta promotes oxidative damage and dysfunction of the retinal pigment epithelium

Magali Saint-Geniez; Quincy Charles; Mariana Rosales; Arogya Khadka; Gopalan Gnanaguru; Jared Iacovelli

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3381. doi:

ARVO Annual Meeting Abstract June 2017

Endomucin depletion inhibits pathologic retinal vascularization in vivo

Patricia A D'Amore; Cindy Park-Windhol; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4058. doi:

ARVO Annual Meeting Abstract September 2016

Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by suppressing VEGFR2 signaling

Patricia A D'Amore; Cindy Park-Windhol; Yin Shan Eric Ng; Jinling Yang; Vincent Primo; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3637. doi:

ARVO Annual Meeting Abstract September 2016

Feedback Regulation of IRE1 During Unfolded Protein Response in RPE

Sarah Melissa P. Jacobo; Maximilian J Gerhardt; arogya Khadka; Daniel Diaz-Aguilar; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):254. doi:

ARVO Annual Meeting Abstract September 2016

Characterization of Mitochondrial and Metabolic Changes Following Retinal Detachment

Daniel Diaz-Aguilar; Zhaohui Li; Yoko Okunuki; arogya Khadka; Sarah Melissa P. Jacobo; Kip M Connor; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Retinal Cell Biology March 2016

PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity

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Jared Iacovelli; Glenn C. Rowe; Arogya Khadka; Daniel Diaz-Aguilar; Carrie Spencer; Zoltan Arany; Magali Saint-Geniez
TAGS: antioxidants, fatty acids, metabolism, gene expression, mitochondria, cell death, genes, oxidants, proteins, cell respiration, protein overexpression
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):1038-1051. doi: 10.1167/iovs.15-17758

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Shedding of Endomucin by Endothelial Cells under Inflammatory Conditions: Involvement of Matrix Metalloproteases

Jinling Yang; Magali Saint-Geniez; Yin Shan Eric Ng; Marsha A. Moses; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3104. doi:

ARVO Annual Meeting Abstract June 2015

Endomucin Plays a Role in Developmental Retinal Vascularization and in VEGF-Induced Endothelial Cell Migration, Growth, and Morphogenesis In Vitro

Cindy Park-Windhol; Jinling Yang; Vincent Primo; Yin Shan Eric Ng; Magali Saint-Geniez; Patricia A D'Amore

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3404. doi:

ARVO Annual Meeting Abstract June 2015

Control of human RPE differentiation and metabolism by PGC-1α: implications for AMD

Magali Saint-Geniez; Jared Iacovelli; Glenn Rowe; Zoltan Arany

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):830. doi:

ARVO Annual Meeting Abstract April 2014

Synergistic interaction between endothelial cells and retinal pigment epithelium

Magali Saint-Geniez; Carrie Spencer; Stephanie Abend; Kevin McHugh

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):383. doi:

ARVO Annual Meeting Abstract April 2014

PGC-1 alpha regulates human RPE oxidative metabolism and anti-oxidant capacity

Jared Iacovelli; Glenn C Rowe; Zoltan Arany; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1740. doi:

ARVO Annual Meeting Abstract April 2014

Patient-specific modeling of retinal oxygen as a predictor of AMD progression

Kevin McHugh; Leon Kwark; Sina Farsiu; Leo A Kim; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5217. doi:

ARVO Annual Meeting Abstract April 2014

The Alternative Complement Pathway Facilitates Neovessel Regression

Harry Sweigard; Ryoji Yanai; Philipp Gaissert; Magali Saint-Geniez; Keiko Kataoka; Aristomenis Thanos; Kip M Connor

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5372. doi:

Retina March 2014

Direct Effect of Sodium Iodate on Neurosensory Retina

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Jinmei Wang; Jared Iacovelli; Carrie Spencer; Magali Saint-Geniez
TAGS: oxidative stress, gene expression, electroretinography, genes, iodates, phototransduction, lactate dehydrogenase, mice, retina, sodium, cytotoxicity, toxic effect, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1941-1953. doi: 10.1167/iovs.13-13075

Includes: Supplemental Content

Nantotechnology and Regenerative Medicine March 2014

Porous Poly(ε-Caprolactone) Scaffolds for Retinal Pigment Epithelium Transplantation

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Kevin J. McHugh; Sarah L. Tao; Magali Saint-Geniez
TAGS: polyesters, posterior cruciate ligament, transplantation, ptsd checklist, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1754-1762. doi: 10.1167/iovs.13-12833

ARVO Annual Meeting Abstract June 2013

PGC-1 isoforms regulate photoreceptor response to photo-oxidative stress: relevance to retinal degenerative diseases

Jared Iacovelli; Zoltan Arany; Magali Saint-Geniez

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1796. doi:

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Loss of PGC-1α function in RPE induces EMT and promotes retinal degeneration

Pharmaceutical induction of PGC-1α protects retinal pigment epithelium from oxidative stress

Endomucin (EMCN) Regulates Angiogenesis by Controlling VEGFR2 Endocytosis

PGC-1α is required to maintain RPE metabolism, integrity and function.

PGC-1beta promotes oxidative damage and dysfunction of the retinal pigment epithelium

Endomucin depletion inhibits pathologic retinal vascularization in vivo

Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by suppressing VEGFR2 signaling

Feedback Regulation of IRE1 During Unfolded Protein Response in RPE

Characterization of Mitochondrial and Metabolic Changes Following Retinal Detachment

PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity

Shedding of Endomucin by Endothelial Cells under Inflammatory Conditions: Involvement of Matrix Metalloproteases

Endomucin Plays a Role in Developmental Retinal Vascularization and in VEGF-Induced Endothelial Cell Migration, Growth, and Morphogenesis In Vitro

Control of human RPE differentiation and metabolism by PGC-1α: implications for AMD

Synergistic interaction between endothelial cells and retinal pigment epithelium

PGC-1 alpha regulates human RPE oxidative metabolism and anti-oxidant capacity

Patient-specific modeling of retinal oxygen as a predictor of AMD progression

The Alternative Complement Pathway Facilitates Neovessel Regression

Direct Effect of Sodium Iodate on Neurosensory Retina

Porous Poly(ε-Caprolactone) Scaffolds for Retinal Pigment Epithelium Transplantation

PGC-1 isoforms regulate photoreceptor response to photo-oxidative stress: relevance to retinal degenerative diseases

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