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Lens September 2020

Cohen Syndrome-Associated Cataract Is Explained by VPS13B Functions in Lens Homeostasis and Is Modified by Additional Genetic Factors

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Vincent Lhussiez; Elisabeth Dubus; Quénol Cesar; Niyazi Acar; Emeline F. Nandrot; Manuel Simonutti; Isabelle Audo; Eléonore Lizé; Sylvie Nguyen; Audrey Geissler; André Bouchot; Muhammad Ansar; Serge Picaud; Christel Thauvin-Robinet; Laurence Olivier-Faivre; Laurence Duplomb; Romain Da Costa
TAGS: cataract, lens (device), lens, crystalline, genetic aspects, cohen syndrome, mice, syndrome, homeostasis
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):18. https://doi.org/10.1167/iovs.61.11.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

The development of a therapy for retinitis pigmentosa based on the combined administration of the two products encoded by the nucleoredoxin like-1 gene

Emmanuelle Clerin; Ying Yang; Delphine Pagan; Seiki Achiedo; Julie Degardin; Quénol Cesar; Manuel Simonutti; Géraldine Millet-puel; Frédéric Blond; Najate Ait-Ali; José-Alain Sahel; Thierry Leveillard

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3963.

Retina September 2016

Quantitative and Topographical Analysis of the Losses of Cone Photoreceptors and Retinal Ganglion Cells Under Taurine Depletion

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Wahiba Hadj-Saïd; Nicolas Froger; Ivana Ivkovic; Manuel Jiménez-López; Élisabeth Dubus; Julie Dégardin-Chicaud; Manuel Simonutti; César Quénol; Nathalie Neveux; María Paz Villegas-Pérez; Marta Agudo-Barriuso; Manuel Vidal-Sanz; Jose-Alain Sahel; Serge Picaud; Diego García-Ayuso
TAGS: retina, retinal cone, taurine, retinal degeneration, retinal ganglion cells, mice, opsin
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4692-4703. https://doi.org/10.1167/iovs.16-19535

ARVO Annual Meeting Abstract June 2015

Retinal distribution of cone and retinal ganglion cell degenerations in taurine-depleted mice

Wahiba Hadj Said; Diego García-Ayuso; Nicolas G Froger; Ivana Ivkovic; Manuel Jiménez-López; Julie Degardin; Manuel SIMONUTTI; Manuel Vidal-Sanz; Jose Alain Sahel; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4646.

ARVO Annual Meeting Abstract June 2015

3 months kinetics of Type 1 Diabetes model in Brown Norway rats : Retinal phenotypes and molecular analysis

Provost Alexandra; Brahim El Mathari; Alexandra Trehin; Carine Bernard; Damien Lavier; Annabelle Amiard; Manuel SIMONUTTI; Anais Potey; Samantha Beck; Thomas Debeir

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5182.

ARVO Annual Meeting Abstract June 2015

Cone rescue depends on Rod-derived Cone Viability Factor

Ying Yang; Emmanuelle Clerin; Manuel SIMONUTTI; celine Jaillard; Stephane Fouquet; José-Alain Sahel; Thierry D Leveillard

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5444.

ARVO Annual Meeting Abstract June 2015

Microglial activation in a rat model of NAION

Anne-Laure Remond; Audrey Fel; Manuel SIMONUTTI; Ivana IVKOVIC; Jose Alain Sahel; Phuc LeHoang; Bahram Bodaghi; Serge A Picaud; Valerie Touitou

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5542.

ARVO Annual Meeting Abstract April 2014

Visual phenotyping in mutant mice deleted for the taurine-transporter gene

Wahiba HADJ SAÏD; Nicolas G Froger; Ivana Ivkovic; Manuel Simonutti; Nathalie Neveux; Takashi Ito; Junichi Azuma; José-Alain Sahel; Serge A Picaud

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2362.

ARVO Annual Meeting Abstract April 2014

Minocycline as a neuroprotective agent in a rodent model of NAION

Audrey Fel; Nicolas G Froger; Manuel Simonutti; Steven L Bernstein; Neil Miller; Bahram Bodaghi; Phuc Lehoang; Serge A Picaud; Michel Paques; Valerie Touitou

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5736.

ARVO Annual Meeting Abstract June 2013

The retinal phenotype of an animal model of the HANAC syndrome

Alix Trouillet; Emmanuelle Plaisier; Henri Lorach; Julie Dégardin; Manuel Simonutti; Michel Paques; Jose Sahel; Pierre Ronco; Serge Picaud

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5094.

ARVO Annual Meeting Abstract March 2012

Design of a clinical study of gene therapy for Leber Hereditary Optic Neuropathy

Helene Cwerman-Thibault; Sebastien Augustin; Christophe Lechauve; Jessica Ayache; Manuel Simonutti; Jose-Alain Sahel; Marisol Corral-Debrinski

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1913.

ARVO Annual Meeting Abstract April 2011

Taurine Deficiency Damages Retinal Neurones, Cone Photoreceptors And Retinal Ganglion Cells

David Gaucher; Emilie Arnault; Elisabeth Dubus; Julie Degardin; Manuel Simonutti; Tristan Bourcier; Claude Speeg-Schatz; Jose Alain Sahel; Serge Picaud

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5436.

ARVO Annual Meeting Abstract April 2011

Long-term Transgene Expression And Safety Of a rAAV2 Approach Of Gene Therapy For Leber Hereditary Optic Neuropathy

Helene Cwerman-Thibault; Sebastien Augustin; Aicha Bouaita; Christophe Lechauve; Soufien Sghari; Manuel Simonutti; Michel Paques; Pierre Rustin; Jose A. Sahel; Marisol C. Debrinsky, IV

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1405.

ARVO Annual Meeting Abstract April 2011

Suitability Of A Novel Human Multimodal Slit-lamp Sd-oct To Image Animal Eyes

Serge G. Rosolen; Sylvie Lavillegrand; Mei-Lyn Riviere; Manuel Simonutti; Jose-Alain Sahel; Serge Picaud; Jean-Francois LeGargasson

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1727.

ARVO Annual Meeting Abstract April 2011

A Neuroprotective Molecule For Retinal Ganglion Cells In Different Cellular And Animal Models Of Glaucoma

Nicolas G. Froger; Julie Dégardin; Dorothée Pain; Elisabeth Dubus; Valérie Forster; Manuel Simonutti; Alexis-Pierre Bemelmans; José-Alain Sahel; Serge Picaud

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1874.

Visual Neuroscience November 2008

A Low-Cost and Simple Imaging Technique of the Anterior and Posterior Segments: Eye Fundus, Ciliary Bodies, Iridocorneal Angle

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Jean-Laurent Guyomard; Serge G. Rosolen; Michel Paques; Marie-Noelle Delyfer; Manuel Simonutti; Yann Tessier; José A. Sahel; Jean-François Legargasson; Serge Picaud
TAGS: ciliary body, diagnostic imaging, eye, endoscopy
Invest. Ophthalmol. Vis. Sci.. 2008; 49(11):5168-5174. https://doi.org/10.1167/iovs.07-1340

Retina June 2007

Panretinal, High-Resolution Color Photography of the Mouse Fundus

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Michel Paques; Jean-Laurent Guyomard; Manuel Simonutti; Michel J. Roux; Serge Picaud; Jean-François LeGargasson; José-Alain Sahel
TAGS: color, mice, photography, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2007; 48(6):2769-2774. https://doi.org/10.1167/iovs.06-1099

Retina February 2004

Microvascular Remodeling after Occlusion-Recanalization of a Branch Retinal Vein in Rats

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Olivier Genevois; Michel Paques; Manuel Simonutti; Richard Sercombe; Jacques Seylaz; Alain Gaudric; Jean-Philippe Brouland; José Sahel; Eric Vicaut
TAGS: blood capillaries, central retinal vein, microvessels, rats, recanalization, venule, retina, lasers, microscopy, confocal, dilatation, pathologic
Invest. Ophthalmol. Vis. Sci.. 2004; 45(2):594-600. https://doi.org/10.1167/iovs.03-0764

Retinal Cell Biology October 1999

Glial Cell Line–Derived Neurotrophic Factor Induces Histologic and Functional Protection of Rod Photoreceptors in the rd/rd Mouse

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Maria Frasson; Serge Picaud; Thierry Léveillard; Manuel Simonutti; Saddek Mohand–Said; Henri Dreyfus; David Hicks; José Sahel
TAGS: glial cell-line derived neurotrophic factor, mice, rod photoreceptors, retina
Invest. Ophthalmol. Vis. Sci.. 1999; 40(11):2724-2734.

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Cohen Syndrome-Associated Cataract Is Explained by VPS13B Functions in Lens Homeostasis and Is Modified by Additional Genetic Factors

The development of a therapy for retinitis pigmentosa based on the combined administration of the two products encoded by the nucleoredoxin like-1 gene

Quantitative and Topographical Analysis of the Losses of Cone Photoreceptors and Retinal Ganglion Cells Under Taurine Depletion

Retinal distribution of cone and retinal ganglion cell degenerations in taurine-depleted mice

3 months kinetics of Type 1 Diabetes model in Brown Norway rats : Retinal phenotypes and molecular analysis

Cone rescue depends on Rod-derived Cone Viability Factor

Microglial activation in a rat model of NAION

Visual phenotyping in mutant mice deleted for the taurine-transporter gene

Minocycline as a neuroprotective agent in a rodent model of NAION

The retinal phenotype of an animal model of the HANAC syndrome

Design of a clinical study of gene therapy for Leber Hereditary Optic Neuropathy

Taurine Deficiency Damages Retinal Neurones, Cone Photoreceptors And Retinal Ganglion Cells

Long-term Transgene Expression And Safety Of a rAAV2 Approach Of Gene Therapy For Leber Hereditary Optic Neuropathy

Suitability Of A Novel Human Multimodal Slit-lamp Sd-oct To Image Animal Eyes

A Neuroprotective Molecule For Retinal Ganglion Cells In Different Cellular And Animal Models Of Glaucoma

A Low-Cost and Simple Imaging Technique of the Anterior and Posterior Segments: Eye Fundus, Ciliary Bodies, Iridocorneal Angle

Panretinal, High-Resolution Color Photography of the Mouse Fundus

Microvascular Remodeling after Occlusion-Recanalization of a Branch Retinal Vein in Rats

Glial Cell Line–Derived Neurotrophic Factor Induces Histologic and Functional Protection of Rod Photoreceptors in the rd/rd Mouse

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