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ARVO Annual Meeting Abstract June 2024

Diverse Ancestry Analysis: The IAMDGC 2.0

Michelle Grunin; Mathias Gorski; Nicholas Wheeler; William S Bush; Yeunjoo E Song; Xiaofeng Zhu; Susan Blanton; Margaret A Pericak-Vance; Iris M Heid; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4247.

ARVO Annual Meeting Abstract June 2024

Multivariate Genome-wide Association Study of OCT-derived biomarkers for AMD in the Amish Eye Study

Yeunjoo E. Song; Jessica Cooke Bailey; Farid Rajabli; Muneeswar Gupta Nittala; Renee A Laux; Kristy Miskimen; Daniel A Dorfsman; SriniVas R Sadda; Dwight Stambolian; Margaret A Pericak-Vance; William K Scott; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4241.

ARVO Annual Meeting Abstract June 2024

Resistance to AMD pathology after age 75 is suggestively linked and associated with a region on chromosome 2q12.2 in the Amish Eye Study

William K Scott; Farid Rajabli; Jessica Cooke Bailey; Daniel A Dorfsman; Yeunjoo E. Song; Muneeswar Gupta Nittala; SriniVas R Sadda; Dwight E Stambolian; Jonathan L Haines; Margaret A Pericak-Vance

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4230.

ARVO Annual Meeting Abstract June 2023

Genetic and pathologic predictors of progression from early to advanced age-related macular degeneration

William K Scott; Susan H. Slifer; Kyle M. Scott; Stephen G Schwartz; Jaclyn L. Kovach; SriniVas R Sadda; Muneeswar Gupta Nittala; Jonathan L Haines; Margaret A Pericak-Vance

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):488.

ARVO Annual Meeting Abstract June 2023

Assessment of hyperreflective foci using multimodal imaging in eyes with age-related macular degeneration

Deniz Oncel; Giulia Corradetti; Ye He; Maryam Ashrafkhorasani; Muneeswar Gupta Nittala; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines; SriniVas R Sadda

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2173.

ARVO Annual Meeting Abstract June 2023

Identifying X-Chromosome Variants Associated with Age-Related Macular Degeneration

Michelle Grunin; Robert P Igo; Yeunjoo E Song; Susan Blanton; Margaret A Pericak-Vance; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2789.

ARVO Annual Meeting Abstract June 2023

Longitudinal evaluation of the distribution of intraretinal hyper-reflective foci in eyes with intermediate age-related macular degeneration.

Aditya Verma; Giulia Corradetti; Ye He; Muneeswar Gupta Nittala; Marco Nassisi; Swetha B Velaga; Jonathan L Haines; Margaret A Pericak-Vance; Dwight Stambolian; SriniVas R Sadda

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2174.

Genetics August 2022

Consequences of a Rare Complement Factor H Variant for Age-Related Macular Degeneration in the Amish

PDF

Andrea R. Waksmunski; Kristy Miskimen; Yeunjoo E. Song; Michelle Grunin; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Larry D. Adams; Laura Caywood; Michael Prough; Dwight Stambolian; William K. Scott; Margaret A. Pericak-Vance; Jonathan L. Haines
TAGS: age-related macular degeneration, alleles, complement factor h, proteins, c-reactive protein, rna
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):8. https://doi.org/10.1167/iovs.63.9.8

Includes: Supplemental Content

Genetics July 2022

Genomewide Association Study of Retinal Traits in the Amish Reveals Loci Influencing Drusen Development and Link to Age-Related Macular Degeneration

PDF

Michael D. Osterman; Yeunjoo E. Song; Muneeswar Nittala; SriniVas R. Sadda; William K. Scott; Dwight Stambolian; Margaret A. Pericak-Vance; Jonathan L. Haines
TAGS: age-related macular degeneration, drusen, genetics, genome-wide association study, genetic risk
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):17. https://doi.org/10.1167/iovs.63.8.17

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Effect of OCT B-scan Density on Sensitivity for Detection of Intraretinal Hyperreflective Foci

Deniz Oncel; Navid Manafi; Muneeswar Gupta nittala; Swetha Bindu Velga; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines; Srinivas R Sadda

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4079 – F0043.

ARVO Annual Meeting Abstract June 2022

Longitudinal Assessment of Area of Reticular Pseudodrusen in Eyes with Age-Related Macular Degeneration

Swetha Bindu Velaga; Muneeswar Gupta nittala; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines; Srinivas R Sadda

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1026 – F0273.

ARVO Annual Meeting Abstract June 2021

Whole genome sequencing and UMI-4C provide novel insights into the genetic architecture and mechanisms underlying North Carolina macular dystrophy, a cis -regulatory disease

Stijn Van de Sompele; Eva D'haene; Thijs Van der Snickt; Sarah Vergult; Petra Liskova; Fadi Shaya; Karen Nuytemans; Jeffery M Vance; Margaret A Pericak-Vance; Andrea L Vincent; Steven Agemy; Kent W Small; Elfride De Baere

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3.

ARVO Annual Meeting Abstract June 2021

Investigation of the use of drusen as a biomarker for age-related macular degeneration reveals shared genetic risk in the Amish

Michael David Osterman; Yeunjoo E Song; Muneeswar Nittala; Srinivas R Sadda; William K Scott; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):170.

ARVO Annual Meeting Abstract June 2021

Alterations of the Ganglion Cell Complex in Age-Related Macular Degeneration: an AMISH Eye Study Analysis

Swetha Bindu Velaga; GAGAN SINGH; Muneeswar Nittala; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines; Srinivas R Sadda

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):103.

ARVO Annual Meeting Abstract June 2021

Risk factors for progression of Age-related Macular Degeneration: Amish Eye Study

Muneeswar Gupta Nittala; Jyotsna Maram; Federico Covi; Swetha Bindu Velaga; Jonathan L Haines; Margaret A Pericak-Vance; Dwight Stambolian; Srinivas R Sadda

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):102.

ARVO Annual Meeting Abstract June 2020

A Genome-wide Association Study of Drusen Traits in the Amish

Michael David Osterman; Yeunjoo E Song; Muneeswar G. Nittala; Srinivas Sadda; William K Scott; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2440.

ARVO Annual Meeting Abstract June 2020

Retinal pigment epithelium (RPE) pigmentary changes are associated with progression from early to advanced age-related macular degeneration (AMD) independent of CFH and ARMS2 risk genotypes.

William K Scott; Susan H. Slifer; Jacob K. Welch; Stephen G Schwartz; Jaclyn L Kovach; Srinivas Sadda; Muneeswar G. Nittala; Jonathan L Haines; Margaret A Pericak-Vance

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4189.

ARVO Annual Meeting Abstract July 2019

Metabolomics reveals changes in fatty acid metabolism in age-related macular degeneration patients

Milam A Brantley; Karan Uppal; Chunyu Ma; Anita Agarwal; Margaret A Pericak-Vance; William K Scott; Jonathan L Haines; Dean Jones; Sabrina L Mitchell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1187.

ARVO Annual Meeting Abstract July 2019

Three loci associated with risk of advanced age-related macular degeneration (AMD) also influence anti-VEGF treatment response

William K Scott; Omar García Rodríguez; Patrice Whitehead-Gay; Larry D. Adams; Jacob K. Welch; Renee Laux; Milam A Brantley; Jaclyn L. Kovach; Stephen G Schwartz; Anita Agarwal; Jonathan L Haines; Margaret A Pericak-Vance

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2968.

ARVO Annual Meeting Abstract July 2019

Genome-wide Association Study of Choroidal Thickness in the Amish

Omar García Rodríguez; Susan Hackleman Slifer; William K Scott; Yeunjoo E. Song; Kristy Miskimen; Muneeswar Gupta Nittala; Srinivas R Sadda; Jonathan L Haines; Margaret A Pericak-Vance; Dwight Stambolian

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2831.

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Diverse Ancestry Analysis: The IAMDGC 2.0

Multivariate Genome-wide Association Study of OCT-derived biomarkers for AMD in the Amish Eye Study

Resistance to AMD pathology after age 75 is suggestively linked and associated with a region on chromosome 2q12.2 in the Amish Eye Study

Genetic and pathologic predictors of progression from early to advanced age-related macular degeneration

Assessment of hyperreflective foci using multimodal imaging in eyes with age-related macular degeneration

Identifying X-Chromosome Variants Associated with Age-Related Macular Degeneration

Longitudinal evaluation of the distribution of intraretinal hyper-reflective foci in eyes with intermediate age-related macular degeneration.

Consequences of a Rare Complement Factor H Variant for Age-Related Macular Degeneration in the Amish

Genomewide Association Study of Retinal Traits in the Amish Reveals Loci Influencing Drusen Development and Link to Age-Related Macular Degeneration

Effect of OCT B-scan Density on Sensitivity for Detection of Intraretinal Hyperreflective Foci

Longitudinal Assessment of Area of Reticular Pseudodrusen in Eyes with Age-Related Macular Degeneration

Whole genome sequencing and UMI-4C provide novel insights into the genetic architecture and mechanisms underlying North Carolina macular dystrophy, a cis -regulatory disease

Investigation of the use of drusen as a biomarker for age-related macular degeneration reveals shared genetic risk in the Amish

Alterations of the Ganglion Cell Complex in Age-Related Macular Degeneration: an AMISH Eye Study Analysis

Risk factors for progression of Age-related Macular Degeneration: Amish Eye Study

A Genome-wide Association Study of Drusen Traits in the Amish

Retinal pigment epithelium (RPE) pigmentary changes are associated with progression from early to advanced age-related macular degeneration (AMD) independent of CFH and ARMS2 risk genotypes.

Metabolomics reveals changes in fatty acid metabolism in age-related macular degeneration patients

Three loci associated with risk of advanced age-related macular degeneration (AMD) also influence anti-VEGF treatment response

Genome-wide Association Study of Choroidal Thickness in the Amish

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