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ARVO Annual Meeting Abstract June 2021

Transcriptomic Analysis of the Mouse Retina after Acute and Chronic Normobaric and Hypobaric Hypoxia

Lynn Jenny Alix Ebner; Marijana Samardzija; Federica Storti; Vyara Todorova; Duygu Karademir; Julian Behr; Fraser Simpson; Markus Thiersch; Christian Grimm

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3007. doi:

ARVO Annual Meeting Abstract June 2021

Single-cell RNA sequencing reveals early responses to degeneration in rods and cones of the rd10 retina

Duygu Karademir; Vyara Todorova; Marijana Samardzija; Lynn Jenny Alix Ebner; Christian Grimm

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):461. doi:

ARVO Annual Meeting Abstract July 2018

HDAC inhibition protects degenerating cones in the cpfl1 mouse by increasing H3K27 and H3K9 tri-methylation

Dragana Trifunovic; Klaudija Masarini; Christian Grimm; Marius Ueffing; Marijana Samardzija

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4447. doi:

ARVO Annual Meeting Abstract July 2018

HIF1A is the responsible factor for cone degeneration and subretinal neovascularization in a mouse model of chronic hypoxia

Maya Barben; Christian Schori; Christian Grimm; Marijana Samardzija

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):965. doi:

ARVO Annual Meeting Abstract September 2016

Slowing and prevention of vision loss in Retinitis Pigmentosa of the 'Protein Logistics Disease' type

Mathias W Seeliger; Susanne C Beck; Marina Garcia Garrido; Vithiyanjali Sothilingam; Regine Muehlfriedel; Marijana Samardzija; Christian Grimm; Peter Humphries; G Jane Farrar; Peter Carmeliet; Naoyuki Tanimoto

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2735. doi:

ARVO Annual Meeting Abstract September 2016

Inactivation of Hif1a rescues rods and cones from degeneration induced by a chronic hypoxia-like response: HIF1A as therapeutic target in AMD?

Christian Grimm; Maya Barben; Divya Ail; Brigitt Kast; Christian Schori; Christina Giger-Lange; Stylianos Michalakis; Marijana Samardzija

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Sodium 4-Phenylbutyrate Improves Cone Survival and Function in a Mouse Model for Leber Congenital Amaurosis

Songhua Li; Marijana Samardzija; Zhihui Yang; Christian Grimm; Minghao Jin

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3623. doi:

Retinal Cell Biology December 2015

Measuring In Vivo Free Radical Production by the Outer Retina

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Bruce A. Berkowitz; Bryce X. Bredell; Christopher Davis; Marijana Samardzija; Christian Grimm; Robin Roberts
TAGS: free radicals, magnetic resonance imaging, oxidative stress, retina, iodates, sodium, superoxides, mice, diabetes mellitus
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):7931-7938. doi: https://doi.org/10.1167/iovs.15-18420

ARVO Annual Meeting Abstract June 2015

A chronic hypoxia-like response leads to cone degeneration

Maya Barben; Christian Schori; Christian Grimm; Marijana Samardzija

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4645. doi:

ARVO Annual Meeting Abstract June 2015

Attempts to increase protein level, membrane-association, and isomerase activity of R91W RPE65 in mouse model

Songhua Li; Marijana Samardzija; Zhihui Yang; Christian Grimm; Minghao Jin

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5454. doi:

Retinal Cell Biology August 2014

A Mouse Model for Studying Cone Photoreceptor Pathologies

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Marijana Samardzija; Christian Caprara; Severin R. Heynen; Sarah Willcox DeParis; Isabelle Meneau; Ghislaine Traber; Cavit Agca; Johannes von Lintig; Christian Grimm
TAGS: mice, retina, retinal cone, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2014; 55(8):5304-5313. doi: https://doi.org/10.1167/iovs.14-14789

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

In Vivo Analysis Reveals Novel Aspects of Retinal Disease Progression in Rsh1-/Y Mice but no Therapeutic Effect of Carbonic Anhydrase Inhibition

Ahmad Zhour; Christian Grimm; Marijana Samardzija; Tobias Peters; Torsten Strasser; Sylvia Bolz; Bernhard H. F. Weber; Eberhart Zrenner; M. Dominik Fischer

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1134. doi:

Retinal Cell Biology July 2011

Normoxic Activation of Hypoxia-Inducible Factors in Photoreceptors Provides Transient Protection against Light-Induced Retinal Degeneration

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Christina Lange; Severin R. Heynen; Naoyuki Tanimoto; Markus Thiersch; Yun-Zheng Le; Isabelle Meneau; Mathias W. Seeliger; Marijana Samardzija; Christian Caprara; Christian Grimm
TAGS: hypoxia, mice, opsin, photoreceptors, retinal degeneration, rod photoreceptors, retina, tissue degeneration, proteins
Invest. Ophthalmol. Vis. Sci.. 2011; 52(8):5872-5880. doi: https://doi.org/10.1167/iovs.11-7204

ARVO Annual Meeting Abstract April 2011

Structural And Functional Characteristics Of A Pigmentary Chorioretinopathy Observed In The Chinese Crested Dog

Kristina Narfstrom; Sari Jalomäki; Freya Mowat; Marijana Samardzija; Christian Grimm

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1835. doi:

ARVO Annual Meeting Abstract April 2011

Deleterious Actions Of Vegf On The Blood Retinal Barrier And Photoreceptor Survival In The Light-damage Model

Maite Cachafeiro; Alexis-Pierre Bemelmans; Marijana Samardzija; Andreas Wenzel; Christian Grimm; Yvan Arsenijevic

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1848. doi:

Retinal Cell Biology April 2011

HIF1A Is Essential for the Development of the Intermediate Plexus of the Retinal Vasculature

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Christian Caprara; Markus Thiersch; Christina Lange; Sandrine Joly; Marijana Samardzija; Christian Grimm
TAGS: hypoxia inducible factor 1, alpha subunit, mice, retinal vasculature, retina
Invest. Ophthalmol. Vis. Sci.. 2011; 52(5):2109-2117. doi: https://doi.org/10.1167/iovs.10-6222

Retinal Cell Biology March 2009

Nonessential Role of β3 and β5 Integrin Subunits for Efficient Clearance of Cellular Debris after Light-Induced Photoreceptor Degeneration

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Sandrine Joly; Marijana Samardzija; Andreas Wenzel; Markus Thiersch; Christian Grimm
TAGS: drug clearance, integrins, light exposure, mice, monocyte chemoattractant protein-1, photoreceptors, tissue degeneration, retina, macrophages, chemokines
Invest. Ophthalmol. Vis. Sci.. 2009; 50(3):1423-1432. doi: https://doi.org/10.1167/iovs.08-2432

Biochemistry and Molecular Biology December 2006

Caspase-1 Ablation Protects Photoreceptors in a Model of Autosomal Dominant Retinitis Pigmentosa

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Marijana Samardzija; Andreas Wenzel; Markus Thiersch; Rico Frigg; Charlotte Remé; Christian Grimm
TAGS: ablation, caspase-1, photoreceptors, retinal degeneration, mice, retinitis pigmentosa, retina, cisplatin/etoposide protocol
Invest. Ophthalmol. Vis. Sci.. 2006; 47(12):5181-5190. doi: https://doi.org/10.1167/iovs.06-0556

Retinal Cell Biology June 2003

The Genetic Modifier Rpe65Leu 450 : Effect on Light Damage Susceptibility in c- Fos -Deficient Mice

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Andreas Wenzel; Christian Grimm; Marijana Samardzija; Charlotte E. Remé
TAGS: disease susceptibility, mice, genetics, transcription factor ap-1, rhodopsin
Invest. Ophthalmol. Vis. Sci.. 2003; 44(6):2798-2802. doi: https://doi.org/10.1167/iovs.02-1134

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Transcriptomic Analysis of the Mouse Retina after Acute and Chronic Normobaric and Hypobaric Hypoxia

Single-cell RNA sequencing reveals early responses to degeneration in rods and cones of the rd10 retina

HDAC inhibition protects degenerating cones in the cpfl1 mouse by increasing H3K27 and H3K9 tri-methylation

HIF1A is the responsible factor for cone degeneration and subretinal neovascularization in a mouse model of chronic hypoxia

Slowing and prevention of vision loss in Retinitis Pigmentosa of the 'Protein Logistics Disease' type

Inactivation of Hif1a rescues rods and cones from degeneration induced by a chronic hypoxia-like response: HIF1A as therapeutic target in AMD?

Sodium 4-Phenylbutyrate Improves Cone Survival and Function in a Mouse Model for Leber Congenital Amaurosis

Measuring In Vivo Free Radical Production by the Outer Retina

A chronic hypoxia-like response leads to cone degeneration

Attempts to increase protein level, membrane-association, and isomerase activity of R91W RPE65 in mouse model

A Mouse Model for Studying Cone Photoreceptor Pathologies

In Vivo Analysis Reveals Novel Aspects of Retinal Disease Progression in Rsh1-/Y Mice but no Therapeutic Effect of Carbonic Anhydrase Inhibition

Normoxic Activation of Hypoxia-Inducible Factors in Photoreceptors Provides Transient Protection against Light-Induced Retinal Degeneration

Structural And Functional Characteristics Of A Pigmentary Chorioretinopathy Observed In The Chinese Crested Dog

Deleterious Actions Of Vegf On The Blood Retinal Barrier And Photoreceptor Survival In The Light-damage Model

HIF1A Is Essential for the Development of the Intermediate Plexus of the Retinal Vasculature

Nonessential Role of β3 and β5 Integrin Subunits for Efficient Clearance of Cellular Debris after Light-Induced Photoreceptor Degeneration

Caspase-1 Ablation Protects Photoreceptors in a Model of Autosomal Dominant Retinitis Pigmentosa

The Genetic Modifier Rpe65Leu 450 : Effect on Light Damage Susceptibility in c- Fos -Deficient Mice

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