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ARVO Annual Meeting Abstract June 2020

Dissecting the function of IQCB1/NPHP5, associated with retinal ciliopathies, by targeting its endogenous interactome

Ideke J.C. Lamers; Filine van den Bosch; Kim Klarenaar; Lisa Elze; Marius Ueffing; Karsten Boldt; Ronald Roepman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4008. doi:

Articles December 2019

Chromatic Full-Field Stimulus Threshold and Pupillography as Functional Markers for Late-Stage, Early-Onset Retinitis Pigmentosa Caused by CRB1 Mutations

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Krunoslav T. Stingl; Laura Kuehlewein; Nicole Weisschuh; Saskia Biskup; Frans P. M. Cremers; M. Imran Khan; Carina Kelbsch; Tobias Peters; Marius Ueffing; Barbara Wilhelm; Eberhart Zrenner; Katarina Stingl
TAGS: eye, illness length, mutation, pupil reaction, retinitis pigmentosa
Trans. Vis. Sci. Tech.. 2019; 8(6):45. doi: https://doi.org/10.1167/tvst.8.6.45

ARVO Annual Meeting Abstract July 2019

Complement factor H (CFH) loss leads to a local complement system activation and impaired cell balance in the RPE cells

Angela Armento; Sabina Honisch; Anke Jacob; Dragana Trifunovic; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1242. doi:

ARVO Annual Meeting Abstract July 2019

Effects of Subretinal AAV8 Gene Therapy on Microperimetry in CNGA3 Achromatopsia Patients

G. Alex Ochakovski; Ahmad Zhour; Laura Kuehlewein; Susanne Kohl; Andrea Rindtorff; Karl Ulrich Bartz-Schmidt; Marius Ueffing; Eberhart Zrenner; Stylianos Michalakis; Martin Biel; Bernd Wissinger; Tobias Peters; Barbara Wilhelm; M. Dominik Fischer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2921. doi:

ARVO Annual Meeting Abstract July 2019

Human Retina-on-a-Chip: Merging retinal organoids with Organ-on-a-Chip technology

Kevin Achberger; Christopher Probst; Jasmin Haderspeck; Sylvia Bolz; Virginia Cora; Johanna Chuchuy; Lena Antkowiak; Wadood Haq; Marius Ueffing; Peter Loskill; Stefan Liebau

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3317. doi:

ARVO Annual Meeting Abstract July 2019

Inhibition of VCP structurally and functionally reconstitutes photoreceptor cells in Rh P23H organotypic retina cultures

Blanca Arango-Gonzalez; Merve Sen; Tsui-Fen Chou; Ray Deshaies; Sylvia Bolz; Wadood Haq; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4878. doi:

ARVO Annual Meeting Abstract July 2019

Dipeptidyl deptidase-IV inhibition by sitagliptin slows down retinal neurodegeneration in rd10 mice retinas.

Oksana Kutsyr; Blanca Arango-Gonzalez; Laura Fernandez-Sanchez; Victoria Maneu; Pedro Lax; Antonio F Ambrosio; Marius Ueffing; Nicolas Cuenca

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4879. doi:

ARVO Annual Meeting Abstract July 2019

Pharmacological interference in the VCP/ERAD/proteasome axis rescues photoreceptor degeneration in Rh P23H

Merve Sen; Oksana Kutsyr; Sylvia Bolz; Tsui-Fen Chou; Ray Deshaies; Blanca Arango-Gonzalez; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4881. doi:

ARVO Annual Meeting Abstract July 2019

ARMS2 particularly interacts with modulators of ECM affecting migration behavior of human RPE cells.

Sabina Honisch; Angela Armento; Tina Beyer; Selen Ulusoy; Anke Jacob; Karsten Boldt; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4894. doi:

ARVO Annual Meeting Abstract July 2019

Secondary cone degeneration is prevented by HDAC inhibition

Dragana Trifunovic; Klaudija Masarini; Angela Armento; Jerome E. Roger; Marius Ueffing

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5180. doi:

Articles December 2018

Combined Targeted Analysis of Metabolites and Proteins in Tear Fluid With Regard to Clinical Applications

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Sascha Dammeier; Peter Martus; Franziska Klose; Michael Seid; Dario Bosch; Janina D‘Alvise; Focke Ziemssen; Spyridon Dimopoulos; Marius Ueffing
TAGS: metabolites, proteins, eye
Trans. Vis. Sci. Tech.. 2018; 7(6):22. doi: https://doi.org/10.1167/tvst.7.6.22

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Precision medicine using primary human foetal retinal pigment epithelial cells: effects of zinc supplementation

Eszter Emri; Sascha Dammeier; Franziska Klose; Lajos Csincsik; Marius Ueffing; Imre Lengyel

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3989. doi:

ARVO Annual Meeting Abstract July 2018

HDAC inhibition protects degenerating cones in the cpfl1 mouse by increasing H3K27 and H3K9 tri-methylation

Dragana Trifunovic; Klaudija Masarini; Christian Grimm; Marius Ueffing; Marijana Samardzija

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4447. doi:

ARVO Annual Meeting Abstract July 2018

Delivery and deployment of a ciliary actin dynamics module by PCARE drives the neogenesis of phototransductive membrane disks

Rob W J Collin; Julio Cesar Corral Serrano; Jeroen van Reeuwijk; Anita DM Hoogendoorn; Renate AA Ruigrok; Adem Yildirim; Stef JF Letteboer; Lonneke Duijkers; Sanae Sakami; Krzysztof Palczewski; Karsten Boldt; Uwe Wolfrum; Marius Ueffing; Alex Garanto; Ronald Roepman

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4979. doi:

ARVO Annual Meeting Abstract July 2018

Phenotypic heterogeneity of retinal degenerations caused by mutations in CRX examined by multimodal clinical imaging including adaptive optics retinal camera

Katarina Stingl; Laura Kuehlewein; Melanie Kempf; Francoise Sadler; Fadi Nasser; Bernd Wissinger; Susanne Kohl; Nicole Weisschuh; Marius Ueffing; Eberhart Zrenner

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1516. doi:

ARVO Annual Meeting Abstract July 2018

First Gene Supplementation Therapy for CNGA3-linked Achromatopsia

M Dominik Fischer; Stylianos Michalakis; Barbara Wilhelm; Nadine Kahle; Tobias Peters; Karl Ulrich Bartz-Schmidt; Susanne Kohl; Mathias W Seeliger; Nicole Weisschuh; Ditta Zobor; Eberhart Zrenner; Marius Ueffing; Martin Biel; Bernd Wissinger

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2982. doi:

Retina April 2018

Humoral Immune Response After Intravitreal But Not After Subretinal AAV8 in Primates and Patients

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Felix F. Reichel; Tobias Peters; Barbara Wilhelm; Martin Biel; Marius Ueffing; Bernd Wissinger; Karl U. Bartz-Schmidt; Reinhild Klein; Stylianos Michalakis; M. Dominik Fischer; for the RD-CURE Consortium

Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1910-1915. doi: https://doi.org/10.1167/iovs.17-22494

Includes: Supplemental Content

Retina November 2017

Superior Retinal Gene Transfer and Biodistribution Profile of Subretinal Versus Intravitreal Delivery of AAV8 in Nonhuman Primates

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Immanuel P. Seitz; Stylianos Michalakis; Barbara Wilhelm; Felix F. Reichel; G. Alex Ochakovski; Eberhart Zrenner; Marius Ueffing; Martin Biel; Bernd Wissinger; Karl U. Bartz-Schmidt; Tobias Peters; M. Dominik Fischer; for the RD-CURE Consortium
TAGS: cohort studies, disease vectors, dna, gene transfer techniques, genome, injections, primates, spatial vectors, body tissue, surgical procedures, operative
Invest. Ophthalmol. Vis. Sci.. 2017; 58(13):5792-5801. doi: https://doi.org/10.1167/iovs.17-22473

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

How do patients rate their subjective symptoms after CNGA3 gene therapy: First application of the instrument A3-PRO

Barbara Wilhelm; Andreas Koegel; Nadine Kahle; Tobias Peters; Stylianos Michalakis; Martin Biel; Mathias Seeliger; Eberhart Zrenner; Bernd Wissinger; Susanne Kohl; Marius Ueffing; Karl Ulrich Bartz-Schmidt; Dominik M Fischer; Ditta Zobor

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4678. doi:

ARVO Annual Meeting Abstract June 2017

Cell layer specific proteome of the outer retina: laser capture microdissection of drusen and its cellular environment from paraffin embedded sections

Elod Kortvely; Eszter Emri; Sascha Dammeier; Marius Ueffing; Imre Lengyel

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5247. doi:

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Dissecting the function of IQCB1/NPHP5, associated with retinal ciliopathies, by targeting its endogenous interactome

Chromatic Full-Field Stimulus Threshold and Pupillography as Functional Markers for Late-Stage, Early-Onset Retinitis Pigmentosa Caused by CRB1 Mutations

Complement factor H (CFH) loss leads to a local complement system activation and impaired cell balance in the RPE cells

Effects of Subretinal AAV8 Gene Therapy on Microperimetry in CNGA3 Achromatopsia Patients

Human Retina-on-a-Chip: Merging retinal organoids with Organ-on-a-Chip technology

Inhibition of VCP structurally and functionally reconstitutes photoreceptor cells in Rh P23H organotypic retina cultures

Dipeptidyl deptidase-IV inhibition by sitagliptin slows down retinal neurodegeneration in rd10 mice retinas.

Pharmacological interference in the VCP/ERAD/proteasome axis rescues photoreceptor degeneration in Rh P23H

ARMS2 particularly interacts with modulators of ECM affecting migration behavior of human RPE cells.

Secondary cone degeneration is prevented by HDAC inhibition

Combined Targeted Analysis of Metabolites and Proteins in Tear Fluid With Regard to Clinical Applications

Precision medicine using primary human foetal retinal pigment epithelial cells: effects of zinc supplementation

HDAC inhibition protects degenerating cones in the cpfl1 mouse by increasing H3K27 and H3K9 tri-methylation

Delivery and deployment of a ciliary actin dynamics module by PCARE drives the neogenesis of phototransductive membrane disks

Phenotypic heterogeneity of retinal degenerations caused by mutations in CRX examined by multimodal clinical imaging including adaptive optics retinal camera

First Gene Supplementation Therapy for CNGA3-linked Achromatopsia

Humoral Immune Response After Intravitreal But Not After Subretinal AAV8 in Primates and Patients

Superior Retinal Gene Transfer and Biodistribution Profile of Subretinal Versus Intravitreal Delivery of AAV8 in Nonhuman Primates

How do patients rate their subjective symptoms after CNGA3 gene therapy: First application of the instrument A3-PRO

Cell layer specific proteome of the outer retina: laser capture microdissection of drusen and its cellular environment from paraffin embedded sections

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