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ARVO Annual Meeting Abstract June 2023

Altered Age Related Macular Degeneration-related Gene Expression in iPSC-derived RPE Cells from AMD vs. non-AMD Individuals

Huey Cai; Jie Gong; Lucian V Del Priore; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3189.

ARVO Annual Meeting Abstract June 2023

Phagocytic activity of oxidized photoreceptor rod outer segment (oxROS) in induced pluripotent stem cell (iPSC)-derived retinal pigment epithelial (RPE) cells

Jie Gong; Huey Cai; Lucian V Del Priore; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3188.

ARVO Annual Meeting Abstract June 2022

Oxidative stress-mediated high-throughput screening identifies novel neuroprotective agents that protect RPE and rescues visual function in models of AMD

Jie Gong; Huey Cai; Lucian V Del Priore; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3036 – F0407.

ARVO Annual Meeting Abstract June 2022

Use of iPSC-derived RPE to test the efficacy of elamipretide and SBT-272 in preclinical models of dry AMD

Mark Anthony Fields; Jie Gong; Huey Cai; Lucian Del Priore

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4624 – F0416.

ARVO Annual Meeting Abstract June 2022

iPSC-derived RPE cells from AMD patients display altered mitochondrial function and gene expression on an in vitro model of aged Bruch’s membrane

Huey Cai; Jie Gong; Lucian Del Priore; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4599 – F0391.

ARVO Annual Meeting Abstract June 2021

Differences in gene expression and metabolism among AMD and non-AMD patients arise only after iPSC are differentiated into RPE

Huey Cai; Jie Gong; Lawrence J Rizzolo; Lucian V Del Priore; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):251.

ARVO Annual Meeting Abstract June 2021

Increased Reactive Oxygen Species (ROS) production in Patient-specific iPSC-derived RPE from AMD patients

Jie Gong; Huey Cai; Lucian V Del Priore; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):255.

ARVO Annual Meeting Abstract June 2020

Altered Gene Expression Profile in iPSC-derived RPE Cells from AMD Patients

Huey Cai; Jie Gong; Lawrence J Rizzolo; Lucian V Del Priore; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2276.

ARVO Annual Meeting Abstract June 2020

Decreased phagocytosis of photoreceptor outer segments in patient-specific iPSC-derived RPE on diseased basement membrane

Jie Gong; Huey Cai; Lawrence J Rizzolo; Mark Anthony Fields; Lucian V Del Priore

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4153.

ARVO Annual Meeting Abstract July 2019

Altered Focal-adhesion Pathway Gene Expression Pattern in iPSC-derived RPE Cells derived from AMD Patients

Huey Cai; Jie Gong; Lucian V Del Priore; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1225.

ARVO Annual Meeting Abstract July 2019

High-throughput Screening Identifies Compounds that Protect RPE from Physiological Stressors Present in AMD

Mark Anthony Fields; Huey Cai; Jie Gong; laura abriola; Denton Hoyer; Lucian V Del Priore; Scott Noggle; Daniel Paull

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2990.

ARVO Annual Meeting Abstract July 2019

Decreased ATP production and mitochondrial respiration activity in induced pluripotent stem cell (iPSC)-derived Retinal Pigment Epithelial (RPE) cells from Age-Related Macular degeneration (AMD) patients

Jie Gong; Huey Cai; Mark Anthony Fields; Lucian V Del Priore

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1223.

ARVO Annual Meeting Abstract July 2018

Comparison of phagocytic activity in induced pluripotent Stem Cell (iPSC)-derived retinal pigment epithelial (RPE) cells from age-related macular degeneration (AMD) patients

Jie Gong; Hui Cai; Mark Anthony Fields; Lucian Del Priore

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4588.

ARVO Annual Meeting Abstract July 2018

Synthetic compound MAF20170220-4 Protects Human Retinal Pigment Epithelial Cells from Oxidative Stress-induced Cell Death

Lucian Del Priore; Hui Cai; Jie Gong; Laura Abriola; Mark Anthony Fields

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):768.

ARVO Annual Meeting Abstract July 2018

Aged Basement Membrane Reduces Autophagic Activity in Retinal Pigment Epithelium Through MAPK/ERK Signal Transduction Pathway: Implications for Age-related Macular Degeneration

Hui Cai; Mark Anthony Fields; Jie Gong; Carolyn Cai; Lucian Del Priore

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2481.

ARVO Annual Meeting Abstract September 2016

Altered Transepithelial Resistance of Induced Pluripotent Stem Cell-derived Retinal Pigment Epithelium Obtained from Age-related Macular Degeneration (AMD) Patients

Ernesto F Moreira; Jie Gong; Sibylle Rosendahl; Amanda Barrett; Mark Anthony Fields; Zsolt Ablonczy; Baerbel Rohrer; Lucian V Del Priore

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6034.

Articles October 2015

Reengineering Human Bruch's Membrane Increases Rod Outer Segment Phagocytosis by Human Retinal Pigment Epithelium

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Ernesto F. Moreira; Hui Cai; Tongalp H. Tezel; Mark A. Fields; Lucian V. Del Priore
TAGS: bruch's basal membrane, nitrites, phagocytosis, retinal pigment epithelium, rod outer segments, detergents, retinal pigment cell, cattle, extracellular matrix, patient isolation
Trans. Vis. Sci. Tech.. 2015; 4(5):10. https://doi.org/10.1167/tvst.4.5.10

Retina July 2015

Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment Epithelium

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Mark A. Fields; Hui Cai; Hannah E. Bowrey; Ernesto F. Moreira; Monika Beck Gooz; Kannan Kunchithapautham; Jie Gong; Emma Vought; Lucian V. Del Priore
TAGS: cd46 antigen, nitrites, vascular endothelial growth factor a, extracellular matrix, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4231-4238. https://doi.org/10.1167/iovs.15-16438

ARVO Annual Meeting Abstract April 2014

Functional Analysis of Human Protein Induced Pluripotent Stem Cell-derived Retinal Pigment Epithelium

Jie Gong; Mark Anthony Fields; Ernesto F Moreira; Yiannis Koutalos; Zsolt Ablonczy; Lucian V Del Priore

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3997.

ARVO Annual Meeting Abstract April 2011

CD46-Mediated Infection of Human Retinal Pigment Epithelium (RPE) with Human Adenovirus Serotype-3 (HAdV3) Induces RPE Death

Hui Cai; Mark A. Fields; Lucian V. Del Priore

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5473.

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Altered Age Related Macular Degeneration-related Gene Expression in iPSC-derived RPE Cells from AMD vs. non-AMD Individuals

Phagocytic activity of oxidized photoreceptor rod outer segment (oxROS) in induced pluripotent stem cell (iPSC)-derived retinal pigment epithelial (RPE) cells

Oxidative stress-mediated high-throughput screening identifies novel neuroprotective agents that protect RPE and rescues visual function in models of AMD

Use of iPSC-derived RPE to test the efficacy of elamipretide and SBT-272 in preclinical models of dry AMD

iPSC-derived RPE cells from AMD patients display altered mitochondrial function and gene expression on an in vitro model of aged Bruch’s membrane

Differences in gene expression and metabolism among AMD and non-AMD patients arise only after iPSC are differentiated into RPE

Increased Reactive Oxygen Species (ROS) production in Patient-specific iPSC-derived RPE from AMD patients

Altered Gene Expression Profile in iPSC-derived RPE Cells from AMD Patients

Decreased phagocytosis of photoreceptor outer segments in patient-specific iPSC-derived RPE on diseased basement membrane

Altered Focal-adhesion Pathway Gene Expression Pattern in iPSC-derived RPE Cells derived from AMD Patients

High-throughput Screening Identifies Compounds that Protect RPE from Physiological Stressors Present in AMD

Decreased ATP production and mitochondrial respiration activity in induced pluripotent stem cell (iPSC)-derived Retinal Pigment Epithelial (RPE) cells from Age-Related Macular degeneration (AMD) patients

Comparison of phagocytic activity in induced pluripotent Stem Cell (iPSC)-derived retinal pigment epithelial (RPE) cells from age-related macular degeneration (AMD) patients

Synthetic compound MAF20170220-4 Protects Human Retinal Pigment Epithelial Cells from Oxidative Stress-induced Cell Death

Aged Basement Membrane Reduces Autophagic Activity in Retinal Pigment Epithelium Through MAPK/ERK Signal Transduction Pathway: Implications for Age-related Macular Degeneration

Altered Transepithelial Resistance of Induced Pluripotent Stem Cell-derived Retinal Pigment Epithelium Obtained from Age-related Macular Degeneration (AMD) Patients

Reengineering Human Bruch's Membrane Increases Rod Outer Segment Phagocytosis by Human Retinal Pigment Epithelium

Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment Epithelium

Functional Analysis of Human Protein Induced Pluripotent Stem Cell-derived Retinal Pigment Epithelium

CD46-Mediated Infection of Human Retinal Pigment Epithelium (RPE) with Human Adenovirus Serotype-3 (HAdV3) Induces RPE Death

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