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Genetics September 2019

MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus

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Ebony Liu; Georgia Kaidonis; Bennet J. McComish; Mark C. Gillies; Sotoodeh Abhary; Rohan W. Essex; John H. Chang; Bishwanath Pal; Mark Daniell; Stewart Lake; Nikolai Petrovsky; Alex W. Hewitt; Alicia Jenkins; Ecosse L. Lamoureux; Jonathan M. Gleadle; Jamie E. Craig; Kathryn P. Burdon
TAGS: diabetes mellitus, type 1, diabetic retinopathy, genes, genetics, micrornas, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3937-3942. doi: 10.1167/iovs.18-25570

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

A bioenergetic crisis in the retinal pigment epithelium contributes to photoreceptor degeneration

Weiyong Shen; Ashish Easow Mathai; Victoria Pye; So-Ra Lee; Michelle X. Yam; Rui Zhang; Ling Zhu; Pankaj Seth; Joshua L Dunaief; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3866. doi:

ARVO Annual Meeting Abstract July 2019

The differential expression of aquaporin-4 (AQP4) in Müller cells from human macular and peripheral retina.

Ling Zhu; Yuyi You; Ting Zhang; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4392. doi:

ARVO Annual Meeting Abstract July 2019

Selectively knocking down insulin receptor in rods disrupts glucose flux and leads to photoreceptor degeneration

Rui Zhang; Weiyong Shen; Victoria Pye; Ashish Easow Mathai; So-Ra Lee; Michelle Yam; Ling Zhu; Ching-Kang Jason Chen; Jianhai Du; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1670. doi:

ARVO Annual Meeting Abstract July 2019

Comparison of Serine Biosynthesis in Human Retinal Pigment Epithelium from the Macula and Periphery

Ting Zhang; Shaoxue Zeng; Ling Zhu; Weiyong Shen; Jiawen Fan; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1701. doi:

ARVO Annual Meeting Abstract July 2019

Ten-Year Treatment Outcomes of Neovascular Age-Related Macular Degeneration

Mark C Gillies; SANJEEB BHANDARI; Benjamin Wolff; Jennifer Joan Arnold; Rohan W Essex; Stephanie Young; David M Squirrell; Daniel Barthelmes; Vuong Nguyen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):111. doi:

ARVO Annual Meeting Abstract July 2019

Outcomes of suspending VEGF inhibitors for neovascular age-related macular degeneration when lesions have been inactive for 3 months

Vuong Nguyen; Anagha Vaze; Samanta Fraser-Bell; Jennifer Joan Arnold; Rohan W Essex; Daniel Barthelmes; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):139. doi:

ARVO Annual Meeting Abstract July 2019

A randomised clinical trial of slow versus fast intravitreal injection of ranibizumab (Lucentis®) and its impact on intraocular pressure (the Speed IOP Study)

Samantha Fraser-Bell; Sophia Zagora; Hemal Mehta; Anna Campain; Hon Seng Wong; Yeung Aaron; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):79. doi:

ARVO Annual Meeting Abstract July 2019

Changes in real world treatment patterns for diabetic macular edema and five year treatment outcomes: data from the Fight Retinal Blindness! Project

SANJEEB BHANDARI; Anne Catherine Biechl; Jennifer Joan Arnold; Stephanie Young; Samanta Fraser-Bell; Hemal Mehta; Mark C Gillies; Daniel Barthelmes; Vuong Nguyen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2602. doi:

ARVO Annual Meeting Abstract July 2019

Twenty-four month outcomes of inflammatory choroidal neovascularization treated with intravitreal anti vascular endothelial growth factors: a comparison between two treatment regimens

Alessandro Invernizzi; Francesco Pichi; Richard Symes; Sophia Zagora; Vuong Nguyen; Stefano Erba; Alba Xhepa; Luca De Simone; Luca Cimino; Mark C Gillies; Peter J McCluskey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3859. doi:

ARVO Annual Meeting Abstract July 2019

Real-world outcomes in patients with macular oedema secondary to central retinal vein occlusion receiving intravitreal anti-VEGF therapy in a UK public hospital setting

Sarah Ah-Moye; Pardis Zalmay; Magnus Theodorsson; Martin Lynn Harris; Riaz Asaria; Adrian Hunt; Daniel Barthelmes; Mark C Gillies; Vuong Nguyen; Hemal Mehta

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4061. doi:

Retinal Cell Biology December 2018

A Combination Therapy Targeting Endoglin and VEGF-A Prevents Subretinal Fibro-Neovascularization Caused by Induced Müller Cell Disruption

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Weiyong Shen; So-Ra Lee; Michelle Yam; Ling Zhu; Ting Zhang; Victoria Pye; Ashish Easow Mathai; Keiichi Shibagaki; Jin-Zhong Zhang; Takeshi Matsugi; Mark C. Gillies
TAGS: endoglin, antibodies, neovascularization, pathologic, combined modality therapy, vascular endothelial growth factor a
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6075-6088. doi: 10.1167/iovs.18-25628

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Comparison of Ranibizumab and Aflibercept in Patients with Neovascular Age-Related Macular Degeneration treated following a ‘Treat and Extend’ protocol: efficacy variables from the pre-specified 12-month interim analysis of the RIVAL study

Mark C Gillies; Alex Hunyor; Jennifer Arnold; Francois Pecheur; Kathryn Underhill; Robyn H Guymer; Ian McAllister

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):840. doi:

ARVO Annual Meeting Abstract July 2018

Selectively knocking down hexokinase 2 in rods leads to retinal degeneration

Rui Zhang; Weiyong Shen; So-Ra Lee; Michelle X. Yam; Ling Zhu; Ashish Easow Mathai; Ching-Kang Jason Chen; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1003. doi:

ARVO Annual Meeting Abstract July 2018

Tolerating Subretinal Fluid in the Treatment of Neovascular Age-Related Macular Degeneration With Ranibizumab Using a Treat and Extend Regimen

Jennifer Arnold; Caroline Markey; Ian McAllister; Mark C Gillies; Alex Hunyor; Robyn H Guymer

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1461. doi:

ARVO Annual Meeting Abstract July 2018

Trainee-led vs. specialist-led management of neovascular age-related macular degeneration.

Rohan W. Essex; Vuong Nguyen; Vincent Daien; Sarah Steinmann; Richard Walton; Mark C Gillies; Daniel Barthelmes

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1463. doi:

ARVO Annual Meeting Abstract July 2018

Comparison of Serine metabolism in Müller Cells from the Macula and Peripheral Retina

Ting Zhang; Ling Zhu; Michele C Madigan; Weiyong Shen; Bobak Bahrami; Jianhai Du; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1477. doi:

ARVO Annual Meeting Abstract July 2018

The consequences of selectively knocking down key metabolic genes in Müller cells of the mouse retina

Weiyong Shen; So-Ra Lee; Michelle X. Yam; Nigel L Barnett; Ashish Easow Mathai; Rui Zhang; Ling Zhu; James Hurley; Jianhai Du; Pankaj Seth; Yoshio Hirabayashi; Shigeki Furuya; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1492. doi:

ARVO Annual Meeting Abstract July 2018

A Probabilistic Forecast of 12 Month Visual Outcomes of nAMD

Vuong Nguyen; Kelvin Teo; Judy Simpson; Vincent Daien; Daniel Barthelmes; Mark C Gillies; Richard Walton

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):829. doi:

ARVO Annual Meeting Abstract July 2018

Real-world visual outcomes at 24 weeks in patients with diabetic macular edema receiving aflibercept intravitreal injections as per UK license.

Charles Hennings; Mira Deshmukh; Vuong Nguyen; Martin Harris; Riaz Asaria; Daniel Barthelmes; Mark C Gillies; Hemal Mehta

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3616. doi:

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MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus

A bioenergetic crisis in the retinal pigment epithelium contributes to photoreceptor degeneration

The differential expression of aquaporin-4 (AQP4) in Müller cells from human macular and peripheral retina.

Selectively knocking down insulin receptor in rods disrupts glucose flux and leads to photoreceptor degeneration

Comparison of Serine Biosynthesis in Human Retinal Pigment Epithelium from the Macula and Periphery

Ten-Year Treatment Outcomes of Neovascular Age-Related Macular Degeneration

Outcomes of suspending VEGF inhibitors for neovascular age-related macular degeneration when lesions have been inactive for 3 months

A randomised clinical trial of slow versus fast intravitreal injection of ranibizumab (Lucentis®) and its impact on intraocular pressure (the Speed IOP Study)

Changes in real world treatment patterns for diabetic macular edema and five year treatment outcomes: data from the Fight Retinal Blindness! Project

Twenty-four month outcomes of inflammatory choroidal neovascularization treated with intravitreal anti vascular endothelial growth factors: a comparison between two treatment regimens

Real-world outcomes in patients with macular oedema secondary to central retinal vein occlusion receiving intravitreal anti-VEGF therapy in a UK public hospital setting

A Combination Therapy Targeting Endoglin and VEGF-A Prevents Subretinal Fibro-Neovascularization Caused by Induced Müller Cell Disruption

Comparison of Ranibizumab and Aflibercept in Patients with Neovascular Age-Related Macular Degeneration treated following a ‘Treat and Extend’ protocol: efficacy variables from the pre-specified 12-month interim analysis of the RIVAL study

Selectively knocking down hexokinase 2 in rods leads to retinal degeneration

Tolerating Subretinal Fluid in the Treatment of Neovascular Age-Related Macular Degeneration With Ranibizumab Using a Treat and Extend Regimen

Trainee-led vs. specialist-led management of neovascular age-related macular degeneration.

Comparison of Serine metabolism in Müller Cells from the Macula and Peripheral Retina

The consequences of selectively knocking down key metabolic genes in Müller cells of the mouse retina

A Probabilistic Forecast of 12 Month Visual Outcomes of nAMD

Real-world visual outcomes at 24 weeks in patients with diabetic macular edema receiving aflibercept intravitreal injections as per UK license.

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