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Retinal Cell Biology December 2018

A Combination Therapy Targeting Endoglin and VEGF-A Prevents Subretinal Fibro-Neovascularization Caused by Induced Müller Cell Disruption

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Weiyong Shen; So-Ra Lee; Michelle Yam; Ling Zhu; Ting Zhang; Victoria Pye; Ashish Easow Mathai; Keiichi Shibagaki; Jin-Zhong Zhang; Takeshi Matsugi; Mark C. Gillies
TAGS: endoglin, antibodies, neovascularization, pathologic, combined modality therapy, vascular endothelial growth factor a
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6075-6088. doi: 10.1167/iovs.18-25628

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Comparison of Ranibizumab and Aflibercept in Patients with Neovascular Age-Related Macular Degeneration treated following a ‘Treat and Extend’ protocol: efficacy variables from the pre-specified 12-month interim analysis of the RIVAL study

Mark C Gillies; Alex Hunyor; Jennifer Arnold; Francois Pecheur; Kathryn Underhill; Robyn H Guymer; Ian McAllister

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):840. doi:

ARVO Annual Meeting Abstract July 2018

Selectively knocking down hexokinase 2 in rods leads to retinal degeneration

Rui Zhang; Weiyong Shen; So-Ra Lee; Michelle X. Yam; Ling Zhu; Ashish Easow Mathai; Ching-Kang Jason Chen; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1003. doi:

ARVO Annual Meeting Abstract July 2018

Tolerating Subretinal Fluid in the Treatment of Neovascular Age-Related Macular Degeneration With Ranibizumab Using a Treat and Extend Regimen

Jennifer Arnold; Caroline Markey; Ian McAllister; Mark C Gillies; Alex Hunyor; Robyn H Guymer

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1461. doi:

ARVO Annual Meeting Abstract July 2018

Trainee-led vs. specialist-led management of neovascular age-related macular degeneration.

Rohan W. Essex; Vuong Nguyen; Vincent Daien; Sarah Steinmann; Richard Walton; Mark C Gillies; Daniel Barthelmes

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1463. doi:

ARVO Annual Meeting Abstract July 2018

Comparison of Serine metabolism in Müller Cells from the Macula and Peripheral Retina

Ting Zhang; Ling Zhu; Michele C Madigan; Weiyong Shen; Bobak Bahrami; Jianhai Du; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1477. doi:

ARVO Annual Meeting Abstract July 2018

The consequences of selectively knocking down key metabolic genes in Müller cells of the mouse retina

Weiyong Shen; So-Ra Lee; Michelle X. Yam; Nigel L Barnett; Ashish Easow Mathai; Rui Zhang; Ling Zhu; James Hurley; Jianhai Du; Pankaj Seth; Yoshio Hirabayashi; Shigeki Furuya; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1492. doi:

ARVO Annual Meeting Abstract July 2018

A Probabilistic Forecast of 12 Month Visual Outcomes of nAMD

Vuong Nguyen; Kelvin Teo; Judy Simpson; Vincent Daien; Daniel Barthelmes; Mark C Gillies; Richard Walton

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):829. doi:

ARVO Annual Meeting Abstract July 2018

Real-world visual outcomes at 24 weeks in patients with diabetic macular edema receiving aflibercept intravitreal injections as per UK license.

Charles Hennings; Mira Deshmukh; Vuong Nguyen; Martin Harris; Riaz Asaria; Daniel Barthelmes; Mark C Gillies; Hemal Mehta

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3616. doi:

ARVO Annual Meeting Abstract July 2018

Genetic variants in microRNA genes and microRNA binding sites associated with diabetic retinopathy

Ebony Liu; Georgia Kaidonis; Bennet McComish; Mark C Gillies; Sotoodeh Abhary; Mark Daniell; Nikolai Petrovsky; Jonathan Gleadle; Jamie E. Craig; Kathryn P Burdon

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3017. doi:

ARVO Annual Meeting Abstract July 2018

Choroidal changes may predict neovascular activity in exudative age related macular degeneration

Alessandro Invernizzi; Eleonora Benatti; Mariano Cozzi; Stefano Erba; Shiva Vaishnavi; Kiran Vupparaboina; Giovanni Staurenghi; Jay Chhablani; Mark C Gillies; Francesco Viola

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3253. doi:

ARVO Annual Meeting Abstract July 2018

Effects of anti-VEGF drugs on human retinal pigment epithelium under oxidative stress

Bobak Bahrami; Ling Zhu; Ting Zhang; Andrew Chang; Mark C Gillies; Weiyong Shen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4000. doi:

ARVO Annual Meeting Abstract July 2018

The outcomes of corneal cross-linking for Keratoconus from routine clinical practice across 3 sites in Australia: Results from the Save Sight Keratoconus Registry

Alex Ferdi; Vuong Nguyen; Jeremy Tan; Yves Kerdraon; John Males; Nigel Morlet; Peter Beckinsale; Richard A Mills; Chris Go; Mark Daniell; Elsie Chan; Daniel Barthelmes; Amparo Herrera-Bond; Marco Garcia; Mark C Gillies; Stephanie L Watson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4380. doi:

ARVO Annual Meeting Abstract July 2018

Using cell reprogramming technology to convert Müller glia into photoreceptors

Raymond Ching Bong Wong; Tu Nguyen; Lucy Lyujie Fang; Camden Lo; Jafar Jabbari; Sandy Hung; Rick Guei-Sheung Liu; Chi D Luu; Mark C Gillies; Alex Hewitt

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4578. doi:

ARVO Annual Meeting Abstract July 2018

Five year outcomes of the Bevordex Study (a multicenter randomized clinical trial of intravitreal bevacizumab versus intravitreal dexamethasone).

Elisa Eleanor Cornish; Kelvin Yi Chong Teo; Mark C Gillies; Lyndell L Lim; Ian McAllister; Sutha Sanmugasundram; Vuong Nguyen; Sanjeewa Wickremasinghe; Hemal Mehta; Samantha Fraser-Bell

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4847. doi:

ARVO Annual Meeting Abstract July 2018

Simvastatin Protects Photoreceptors from all-trans-retinal Induced Oxidative Stress with Up-regulating Interphotoreceptors Retinoid Binding Protein

Ling Zhu; Ting Zhang; Weiyong Shen; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5290. doi:

ARVO Annual Meeting Abstract June 2017

Real-world visual outcomes in patients with neovascular age-related macular degeneration receiving aflibercept (Eylea) intravitreal injections at fixed intervals as per UK license

Mehmet Ozturk; Martin Harris; Vuong Nguyen; Daniel Barthelmes; Mark C Gillies; Hemal Mehta

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):881. doi:

ARVO Annual Meeting Abstract June 2017

Characterization of canonical Wnt signalling changes after induced Müller cell disruption in murine retina

Ling Zhu; Weiyong Shen; Ying Wang; Ting Zhang; Bobak Bahrami; Fanfan Zhou; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):611. doi:

ARVO Annual Meeting Abstract June 2017

The effect of Serine/Glycine metabolism on Müller cells mitochondrial function, redox homeostasis and cells’ survival under oxidative stress

Ting Zhang; Ling Zhu; Weiyong Shen; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):803. doi:

ARVO Annual Meeting Abstract June 2017

Effects of ranibizumab and aflibercept on human Müller cells and photoreceptors under stress

Weiyong Shen; Belinda Yau; SoRa Lee; Ling Zhu; Michelle Yam; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):877. doi:

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A Combination Therapy Targeting Endoglin and VEGF-A Prevents Subretinal Fibro-Neovascularization Caused by Induced Müller Cell Disruption

Comparison of Ranibizumab and Aflibercept in Patients with Neovascular Age-Related Macular Degeneration treated following a ‘Treat and Extend’ protocol: efficacy variables from the pre-specified 12-month interim analysis of the RIVAL study

Selectively knocking down hexokinase 2 in rods leads to retinal degeneration

Tolerating Subretinal Fluid in the Treatment of Neovascular Age-Related Macular Degeneration With Ranibizumab Using a Treat and Extend Regimen

Trainee-led vs. specialist-led management of neovascular age-related macular degeneration.

Comparison of Serine metabolism in Müller Cells from the Macula and Peripheral Retina

The consequences of selectively knocking down key metabolic genes in Müller cells of the mouse retina

A Probabilistic Forecast of 12 Month Visual Outcomes of nAMD

Real-world visual outcomes at 24 weeks in patients with diabetic macular edema receiving aflibercept intravitreal injections as per UK license.

Genetic variants in microRNA genes and microRNA binding sites associated with diabetic retinopathy

Choroidal changes may predict neovascular activity in exudative age related macular degeneration

Effects of anti-VEGF drugs on human retinal pigment epithelium under oxidative stress

The outcomes of corneal cross-linking for Keratoconus from routine clinical practice across 3 sites in Australia: Results from the Save Sight Keratoconus Registry

Using cell reprogramming technology to convert Müller glia into photoreceptors

Five year outcomes of the Bevordex Study (a multicenter randomized clinical trial of intravitreal bevacizumab versus intravitreal dexamethasone).

Simvastatin Protects Photoreceptors from all-trans-retinal Induced Oxidative Stress with Up-regulating Interphotoreceptors Retinoid Binding Protein

Real-world visual outcomes in patients with neovascular age-related macular degeneration receiving aflibercept (Eylea) intravitreal injections at fixed intervals as per UK license

Characterization of canonical Wnt signalling changes after induced Müller cell disruption in murine retina

The effect of Serine/Glycine metabolism on Müller cells mitochondrial function, redox homeostasis and cells’ survival under oxidative stress

Effects of ranibizumab and aflibercept on human Müller cells and photoreceptors under stress

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