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Retina February 2022

Spatial Dissociation of Subretinal Drusenoid Deposits and Impaired Scotopic and Mesopic Sensitivity in AMD

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Yuhua Zhang; SriniVas R. Sadda; David Sarraf; Thomas A. Swain; Mark E. Clark; Kenneth R. Sloan; William E. Warriner; Cynthia Owsley; Christine A. Curcio
TAGS: digestive tract decontamination, dissociation, drusen, eye, photophobia, rod photoreceptors, vision, fovea centralis, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):32. doi: https://doi.org/10.1167/iovs.63.2.32

Includes: Supplemental Content

Special Issue December 2020

Exploring a Structural Basis for Delayed Rod-Mediated Dark Adaptation in Age-Related Macular Degeneration Via Deep Learning

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Aaron Y. Lee; Cecilia S. Lee; Marian S. Blazes; Julia P. Owen; Yelena Bagdasarova; Yue Wu; Theodore Spaide; Ryan T. Yanagihara; Yuka Kihara; Mark E. Clark; MiYoung Kwon; Cynthia Owsley; Christine A. Curcio

Trans. Vis. Sci. Tech.. 2020; 9(2):62. doi: https://doi.org/10.1167/tvst.9.2.62

Includes: Supplemental Content

Retina July 2020

Local Abundance of Macular Xanthophyll Pigment Is Associated with Rod- and Cone-Mediated Vision in Aging and Age-Related Macular Degeneration

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Deepayan Kar; Mark E. Clark; Thomas A. Swain; Gerald McGwin, Jr.; Jason N. Crosson; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: age-related macular degeneration, aging, autofluorescence, lutein, pigment, retinal cone, rod photoreceptors, vision, eye, fovea centralis
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):46. doi: https://doi.org/10.1167/iovs.61.8.46

Articles July 2020

Imaging of Age-Related Macular Degeneration by Adaptive Optics Scanning Laser Ophthalmoscopy in Eyes With Aged Lenses or Intraocular Lenses

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Yuhua Zhang; Xiaolin Wang; Mark E. Clark; Christine A. Curcio; Cynthia Owsley
TAGS: age-related macular degeneration, cataract, diagnostic imaging, eye, intraocular lens implant device, lens (device), lens, crystalline, optics, scanning laser ophthalmoscopy, retinal cone
Trans. Vis. Sci. Tech.. 2020; 9(8):41. doi: https://doi.org/10.1167/tvst.9.8.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Hyperreflective foci and specks are associated with delayed rod-mediated dark adaptation in non-neovascular age-related macular degeneration (AMD)

Christine Curcio; Benjamin Echols; Mark E Clark; Thomas Swain; Ling Chen; Yuhua Zhang; Gerald McGwin; David Kilpatrick; Jason Crosson; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1820. doi:

ARVO Annual Meeting Abstract June 2020

Localized xanthophyll carotenoid abundance is associated with rod-mediated dark adaptation and cone-mediated visual acuity in aging and early and intermediate age-related macular degeneration (AMD)

Deepayan Kar; Mark E Clark; Thomas Swain; Gerald McGwin; Jason Crosson; Cynthia Owsley; Kenneth R Sloan; Christine Curcio

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1826. doi:

ARVO Annual Meeting Abstract June 2017

Association between visual function and macular pigment optical density (MPOD) in older eyes in normal macular health

Anna V Zarubina; Carrie E Huisingh; Mark E. Clark; Gerald McGwin; Christine Curcio; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4710. doi:

ARVO Annual Meeting Abstract June 2017

Optic Nerve Head (ONH) In Vivo Biomechanics Assessed by Quantification of the IOP Fluctuations caused by the Ocular Pulse Pressure (OPP)

Massimo Antonio Fazio; Mark E. Clark; Christopher A Girkin

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2456. doi:

ARVO Annual Meeting Abstract June 2017

Do subretinal drusenoid deposits have a spectral fingerprint?

Yuhua Zhang; Xiaolin Wang; Boyu Gu; Mark E. Clark; C. Douglas Witherspoon; Gerald McGwin Jr.; Cynthia Owsley; Christine Curcio

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):305. doi:

Articles June 2017

Natural History of Rod-Mediated Dark Adaptation over 2 Years in Intermediate Age-Related Macular Degeneration

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Cynthia Owsley; Mark E. Clark; Gerald McGwin, Jr
TAGS: age-related macular degeneration, dark adaptation, eye, natural history, rod photoreceptors
Trans. Vis. Sci. Tech.. 2017; 6(3):15. doi: https://doi.org/10.1167/tvst.6.3.15

ARVO Annual Meeting Abstract September 2016

Racial differences in the minimum rim width of the optic nerve

Christopher A Girkin; Lindsay Anne Rhodes; Mark E Clark; Carrie E Huisingh; Massimo Antonio Fazio; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):839. doi:

ARVO Annual Meeting Abstract September 2016

Dynamism and ultrastructure of subretinal drusenoid deposits revealed by adaptive optics scanning laser ophthalmoscopy over 3.5 years

Yuhua Zhang; Xiaolin Wang; Mark E Clark; Cynthia Owsley; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):78. doi:

ARVO Annual Meeting Abstract September 2016

Reflectivity of cone photoreceptors in outer retinal tubulation (ORT) in age-related macular degeneration (AMD)

Katie M Litts; Xiaolin Wang; Mark E Clark; Christine A Curcio; Yuhua Zhang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):29. doi:

Clinical and Epidemiologic Research April 2016

Visual Function in Older Eyes in Normal Macular Health: Association with Incident Early Age-Related Macular Degeneration 3 Years Later

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Cynthia Owsley; Mark E. Clark; Carrie E. Huisingh; Christine A. Curcio; Gerald McGwin, Jr
TAGS: age-related macular degeneration, eye, health, luminance, photophobia, vision, contrast sensitivity, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1782-1789. doi: https://doi.org/10.1167/iovs.15-18962

Multidisciplinary Ophthalmic Imaging July 2015

RefMoB, a Reflectivity Feature Model-Based Automated Method for Measuring Four Outer Retinal Hyperreflective Bands in Optical Coherence Tomography

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Douglas H. Ross; Mark E. Clark; Pooja Godara; Carrie Huisingh; Gerald McGwin; Cynthia Owsley; Katie M. Litts; Richard F. Spaide; Kenneth R. Sloan; Christine A. Curcio
TAGS: optical coherence tomography, histology
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4166-4176. doi: https://doi.org/10.1167/iovs.14-15256

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Mesopic and Scotopic Microperimetry and Multi-Modal Imaging in Eyes with Sub-retinal Drusenoid Deposits (SDD)

Yuhua Zhang; Xiaolin Wang; Mark E Clark; Christine A Curcio; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2618. doi:

ARVO Annual Meeting Abstract June 2015

Association between subretinal drusenoid deposits (SDD) seen by multimodal imaging and dark adaptation (DA) in normal, early, and intermediate age-related macular degeneration (AMD) eyes

David Neely; Anna V Zarubina; Mark E Clark; Carrie E Huisingh; Gregory R Jackson; Gerald McGwin; Christine A Curcio; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2777. doi:

ARVO Annual Meeting Abstract June 2015

Relating retinal morphology on spectral domain optical coherence tomography (SDOCT) to macular function in aging and early to intermediate age-related macular degeneration (AMD)

Monica Bernadette Sevilla; Gerald McGwin, Jr.; Eleonora Lad; Mark E Clark; Eric Yuan; Sina Farsiu; Christine A Curcio; Cynthia Owsley; Cynthia A Toth

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3955. doi:

ARVO Annual Meeting Abstract June 2015

Estimating the prevalence of subretinal drusenoid deposits (SDD) among older adults with healthy macula and age-related macular degeneration (AMD) with multimodal imaging

Anna V Zarubina; David Neely; Mark E Clark; Carrie E Huisingh; Brian C Samuels; Yuhua Zhang; Gerald McGwin; Cynthia Owsley; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5140. doi:

ARVO Annual Meeting Abstract June 2015

Photoreceptor disorder around subretinal drusenoid deposits and drusen revealed by adaptive optics scanning laser ophthalmoscopy

Xiaolin Wang; Tianjiao Zhang; Pooja Gordara; Alexander Meadway; Mark E Clark; Clark Douglas Witherspoon; Christopher A Girkin; Cynthia Owsley; Christine A Curcio; Yuhua Zhang

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5148. doi:

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Spatial Dissociation of Subretinal Drusenoid Deposits and Impaired Scotopic and Mesopic Sensitivity in AMD

Exploring a Structural Basis for Delayed Rod-Mediated Dark Adaptation in Age-Related Macular Degeneration Via Deep Learning

Local Abundance of Macular Xanthophyll Pigment Is Associated with Rod- and Cone-Mediated Vision in Aging and Age-Related Macular Degeneration

Imaging of Age-Related Macular Degeneration by Adaptive Optics Scanning Laser Ophthalmoscopy in Eyes With Aged Lenses or Intraocular Lenses

Hyperreflective foci and specks are associated with delayed rod-mediated dark adaptation in non-neovascular age-related macular degeneration (AMD)

Localized xanthophyll carotenoid abundance is associated with rod-mediated dark adaptation and cone-mediated visual acuity in aging and early and intermediate age-related macular degeneration (AMD)

Association between visual function and macular pigment optical density (MPOD) in older eyes in normal macular health

Optic Nerve Head (ONH) In Vivo Biomechanics Assessed by Quantification of the IOP Fluctuations caused by the Ocular Pulse Pressure (OPP)

Do subretinal drusenoid deposits have a spectral fingerprint?

Natural History of Rod-Mediated Dark Adaptation over 2 Years in Intermediate Age-Related Macular Degeneration

Racial differences in the minimum rim width of the optic nerve

Dynamism and ultrastructure of subretinal drusenoid deposits revealed by adaptive optics scanning laser ophthalmoscopy over 3.5 years

Reflectivity of cone photoreceptors in outer retinal tubulation (ORT) in age-related macular degeneration (AMD)

Visual Function in Older Eyes in Normal Macular Health: Association with Incident Early Age-Related Macular Degeneration 3 Years Later

RefMoB, a Reflectivity Feature Model-Based Automated Method for Measuring Four Outer Retinal Hyperreflective Bands in Optical Coherence Tomography

Mesopic and Scotopic Microperimetry and Multi-Modal Imaging in Eyes with Sub-retinal Drusenoid Deposits (SDD)

Association between subretinal drusenoid deposits (SDD) seen by multimodal imaging and dark adaptation (DA) in normal, early, and intermediate age-related macular degeneration (AMD) eyes

Relating retinal morphology on spectral domain optical coherence tomography (SDOCT) to macular function in aging and early to intermediate age-related macular degeneration (AMD)

Estimating the prevalence of subretinal drusenoid deposits (SDD) among older adults with healthy macula and age-related macular degeneration (AMD) with multimodal imaging

Photoreceptor disorder around subretinal drusenoid deposits and drusen revealed by adaptive optics scanning laser ophthalmoscopy

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