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Articles October 2020

A Ketogenic & Low-Protein Diet Slows Retinal Degeneration in rd10 Mice

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Renee C. Ryals; Samuel J. Huang; Dahlia Wafai; Claire Bernert; William Steele; Makayla Six; Shasank Bonthala; Hope Titus; Paul Yang; Melanie Gillingham; Mark E. Pennesi
TAGS: diet, diet, protein-restricted, mice, proteins, retina, retinal degeneration, electroretinography, serum albumin
Trans. Vis. Sci. Tech.. 2020; 9(11):18. doi: https://doi.org/10.1167/tvst.9.11.18

Includes: Multimedia, Supplemental Content

Articles October 2020

The RUSH2A Study: Best-Corrected Visual Acuity, Full-Field Electroretinography Amplitudes, and Full-Field Stimulus Thresholds at Baseline

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David G. Birch; Peiyao Cheng; Jacque L. Duncan; Allison R. Ayala; Maureen G. Maguire; Isabelle Audo; Janet K. Cheetham; Todd A. Durham; Abigail T. Fahim; Frederick L. Ferris, III; Elise Heon; Rachel M. Huckfeldt; Alessandro Iannaccone; Naheed W. Khan; Eleonora M. Lad; Michel Michaelides; Mark E. Pennesi; Katarina Stingl; Ajoy Vincent; Christina Y. Weng; for the Foundation Fighting Blindness Consortium Investigator Group
TAGS: electroretinography, visual acuity
Trans. Vis. Sci. Tech.. 2020; 9(11):9. doi: https://doi.org/10.1167/tvst.9.11.9

Includes: Supplemental Content

Retina August 2020

Suppression of cGMP-Dependent Photoreceptor Cytotoxicity With Mycophenolate Is Neuroprotective in Murine Models of Retinitis Pigmentosa

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Paul Yang; Rachel Lockard; Hope Titus; Jordan Hiblar; Kyle Weller; Dahlia Wafai; Richard G. Weleber; Robert M. Duvoisin; Catherine W. Morgans; Mark E. Pennesi
TAGS: cyclic gmp, cytotoxicity, mice, photoreceptors, mycophenolate mofetil, retinitis pigmentosa
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):25. doi: https://doi.org/10.1167/iovs.61.10.25

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Multimodal imaging in patients with MYO7A- related Usher syndrome

Leslie Small; Jessica Wong; Mark E Pennesi; Hao Zhou; Ruikang K Wang; Abhishek Chadha; David S Williams; Austin Roorda; Travis Proco; Jacque L Duncan

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):228. doi:

ARVO Annual Meeting Abstract June 2020

Pentosan Polysulfate Maculopathy: Disease Course after Drug Cessation

Rachel Shah; Riley Lyons; Joseph Simonett; Mark E Pennesi; Rajesh C Rao; Nieraj Jain

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1063. doi:

ARVO Annual Meeting Abstract June 2020

Neuroprotective Mechanisms of Dark Rearing on cGMP in rd10 mice

Paul Yang; Hope Titus; Jordan Hiblar; Dahlia Wafai; Robert M Duvoisin; Richard G Weleber; Catherine W Morgans; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2482. doi:

ARVO Annual Meeting Abstract June 2020

Accelerating research in rare inherited retinal disorders (IRDs) through an international consortium

Janet K Cheetham; Allison Ayala; David G Birch; Jacque L Duncan; Todd Durham; Frederick L Ferris; Maureen Maguire; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3356. doi:

ARVO Annual Meeting Abstract June 2020

Baseline visual fields in the RUSH2A study: Associated factors and correlation with measures of disease severity

Jacque L Duncan; Wendi Liang; Isabelle S Audo; David G Birch; Joseph Carroll; Janet K. Cheetham; Laura R Erker; Frederick L Ferris; Elise Heon; Robert Hufnagel; Alessandro Iannaccone; Glenn J Jaffe; Christine N Kay; Maureen Maguire; Michel Michaelides; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3364. doi:

ARVO Annual Meeting Abstract June 2020

The age of patients with retinal degenerative diseases affects the injection pressure required for subretinal gene therapy delivery

Brittni A Scruggs; Huber Martins Vasconcelos Junior; Mark E Pennesi; Steven T Bailey; Andreas K Lauer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4501. doi:

ARVO Annual Meeting Abstract June 2020

Optical coherence tomography artifacts predict adaptive optics scanning light ophthalmoscopy success in achromatopsia

Katie M Litts; Erica N. Woertz; Rachel E Linderman; Byron L Lam; Gerald A Fishman; Mark E Pennesi; Christine N Kay; William W Hauswirth; Joseph Carroll

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5271. doi:

ARVO Annual Meeting Abstract June 2020

Test-retest variability of static perimetry and microperimetry results from the RUSH2A study

Allison Ayala; Wendi Liang; David G Birch; Janet K Cheetham; Elvira N Chegarnov; Jacque L Duncan; Todd Durham; Frederick L Ferris; Eleonora M Lad; Maureen Maguire; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3342. doi:

Review June 2020

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

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Debra A. Thompson; Alessandro Iannaccone; Robin R. Ali; Vadim Y. Arshavsky; Isabelle Audo; James W. B. Bainbridge; Cagri G. Besirli; David G. Birch; Kari E. Branham; Artur V. Cideciyan; Steven P. Daiger; Deniz Dalkara; Jacque L. Duncan; Abigail T. Fahim; John G. Flannery; Roberto Gattegna; John R. Heckenlively; Elise Heon; K. Thiran Jayasundera; Naheed W. Khan; Henry Klassen; Bart P. Leroy; Robert S. Molday; David C. Musch; Mark E. Pennesi; Simon M. Petersen-Jones; Eric A. Pierce; Rajesh C. Rao; Thomas A. Reh; Jose A. Sahel; Dror Sharon; Paul A. Sieving; Enrica Strettoi; Paul Yang; David N. Zacks; The Monaciano Consortium
TAGS: outcome measures, retinal diseases, surrogate endpoints, genetics, vision, natural history, ethics, gene therapy
Trans. Vis. Sci. Tech.. 2020; 9(7):2. doi: https://doi.org/10.1167/tvst.9.7.2

ARVO Annual Meeting Abstract July 2019

Early Treatment with Mycophenolate Reduces Microglial Migration in rd10 mice

Paul Yang; Hope Titus; Kyle Weller; Robert Duvoisin; Richard Weleber; Catherine W Morgans; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):453. doi:

ARVO Annual Meeting Abstract July 2019

An analysis of intraoperative optical coherence tomography findings in subretinal gene therapy surgery

Huber Vasconcelos Junior; Paul Yang; Mark E Pennesi; Brandon J Lujan; Andreas K Lauer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6399. doi:

ARVO Annual Meeting Abstract July 2019

Lipid Nanoparticle Based Messenger RNA Delivery to the Retina

Renee Christine Ryals; Siddharth Patel; Kyle Weller; Mark E Pennesi; Gaurav Sahay

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2916. doi:

ARVO Annual Meeting Abstract July 2019

Neuroprotective Mechanisms of Dark Rearing in rd10 mice

Hope Titus; Kyle Weller; Rachel Lockard; Richard Weleber; Mark E Pennesi; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4887. doi:

ARVO Annual Meeting Abstract July 2019

Natural History of the Progression of RPGR-Associated X-Linked Retinitis Pigmentosa (XOLARIS) Study: Cross-Sectional Analysis of Baseline Characteristics

Moreno Menghini; David G Birch; Camiel Boon; Jacque L Duncan; M Dominik Fischer; Frank G Holz; Carel C B Hoyng; Kamron N Khan; Isabelle Anne Meunier; Mark E Pennesi; Eeva-Marja Kaarina Sankila; Robert E MacLaren

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5168. doi:

ARVO Annual Meeting Abstract July 2019

Expanded clinical spectrum of pentosan polysulfate sodium-associated pigmentary maculopathy

Adam Marcus Hanif; Stanford Taylor; Stephen Armenti; Rachel Shah; Austin Igelman; Mark E Pennesi; Thiran Jayasundera; Paul Yang; Thomas S Hwang; Christina J Flaxel; Rahul Khurana; Joshua D Stein; Nieraj Jain

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3245. doi:

Articles May 2019

Repeatability of Adaptive Optics Automated Cone Measurements in Subjects With Retinitis Pigmentosa and Novel Metrics for Assessment of Image Quality

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Michael J. Gale; Gareth A. Harman; Jimmy Chen; Mark E. Pennesi
TAGS: retinal cone, image quality, retinitis pigmentosa, optics
Trans. Vis. Sci. Tech.. 2019; 8(3):17. doi: https://doi.org/10.1167/tvst.8.3.17

Includes: Supplemental Content

Retina March 2019

Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy

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Dan Jiang; Renee C. Ryals; Samuel J. Huang; Kyle K. Weller; Hope E. Titus; Bryan M. Robb; Firas W. Saad; Ribal A. Salam; Hytham Hammad; Paul Yang; Daniel L. Marks; Mark E. Pennesi
TAGS: fumarates, mice, microglia, retina, retinal degeneration, retinal diseases, light exposure
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1275-1285. doi: https://doi.org/10.1167/iovs.18-24398

Includes: Supplemental Content

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A Ketogenic & Low-Protein Diet Slows Retinal Degeneration in rd10 Mice

The RUSH2A Study: Best-Corrected Visual Acuity, Full-Field Electroretinography Amplitudes, and Full-Field Stimulus Thresholds at Baseline

Suppression of cGMP-Dependent Photoreceptor Cytotoxicity With Mycophenolate Is Neuroprotective in Murine Models of Retinitis Pigmentosa

Multimodal imaging in patients with MYO7A- related Usher syndrome

Pentosan Polysulfate Maculopathy: Disease Course after Drug Cessation

Neuroprotective Mechanisms of Dark Rearing on cGMP in rd10 mice

Accelerating research in rare inherited retinal disorders (IRDs) through an international consortium

Baseline visual fields in the RUSH2A study: Associated factors and correlation with measures of disease severity

The age of patients with retinal degenerative diseases affects the injection pressure required for subretinal gene therapy delivery

Optical coherence tomography artifacts predict adaptive optics scanning light ophthalmoscopy success in achromatopsia

Test-retest variability of static perimetry and microperimetry results from the RUSH2A study

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

Early Treatment with Mycophenolate Reduces Microglial Migration in rd10 mice

An analysis of intraoperative optical coherence tomography findings in subretinal gene therapy surgery

Lipid Nanoparticle Based Messenger RNA Delivery to the Retina

Neuroprotective Mechanisms of Dark Rearing in rd10 mice

Natural History of the Progression of RPGR-Associated X-Linked Retinitis Pigmentosa (XOLARIS) Study: Cross-Sectional Analysis of Baseline Characteristics

Expanded clinical spectrum of pentosan polysulfate sodium-associated pigmentary maculopathy

Repeatability of Adaptive Optics Automated Cone Measurements in Subjects With Retinitis Pigmentosa and Novel Metrics for Assessment of Image Quality

Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy

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