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ARVO Annual Meeting Abstract June 2022

CCL26 expression is elevated in the retinal pigment epithelium in atrophic AMD

Rashmi Dubey; Sushil Kumar Dubey; kyung sik jung; Kabhilan Mohan; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):28. doi:

ARVO Annual Meeting Abstract June 2022

Acetyl-histone profiling of degenerating RPE after selective HDAC1/2 inhibition

Mark Ellsworth Kleinman; Rashmi Dubey; kyung sik jung; Alex Davila; Sushil Kumar Dubey

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):799 – F0358. doi:

ARVO Annual Meeting Abstract June 2022

Technique Optimization for Long-term Culture of Human Primary Retinal Pigment Epithelium Cells

kyung sik jung; Sushil Kumar Dubey; Rashmi Dubey; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3159 – F0433. doi:

ARVO Annual Meeting Abstract June 2022

IL6 dysregulation in retinal pigment epithelium of global Cas9 expressing mouse strain

Sushil Kumar Dubey; Kabhilan Mohan; kyung sik jung; Rashmi Dubey; Qing Jun Wang; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):89 – A0062. doi:

ARVO Annual Meeting Abstract June 2021

Histone deacetylases 1 and 2 regulate chromatin modifying enzymes in mouse retinal pigment epithelium

Sushil Kumar Dubey; Kabhilan Mohan; Kyung-Sik Jung; Jinze Liu; Qing Jun Wang; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3116. doi:

ARVO Annual Meeting Abstract July 2018

withdrawn - Normal Retinal Phenotype in the Aged Global Cas9 Expressing Mouse Strain

Mark Ellsworth Kleinman; Kyung Sik Jung; Sushil Dubey

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):386. doi:

ARVO Annual Meeting Abstract June 2017

Epigenetic regulation of autophagy by histone deacetylases in retinal pigment epithelium

Sushil Kumar Dubey; Dingyuan Lou; Jacob Roney; Kyung Jung; Jennifer Brown; Kabhilan Mohan; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5253. doi:

ARVO Annual Meeting Abstract June 2017

Safety and efficiency of CRISPR-Cas9 gene editing in the retinal pigment epithelium

Mark Ellsworth Kleinman; Sushil Kumar Dubey; Kyung Jung; Jacob Roney; Dingyuan Lou; Jennifer Brown; Kabhilan Mohan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1981. doi:

ARVO Annual Meeting Abstract June 2017

Neutralization of IFNAR1 prevents histone deacetylase inhibitor induced retinal pigment epithelium cell death

kyung sik jung; Kabhilan Mohan; Subhash Prajapati; Sushil Kumar Dubey; Dingyuan Lou; Jacob Roney; Jennifer Brown; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1987. doi:

ARVO Annual Meeting Abstract September 2016

Retinal pigment epithelium atrophy in the Cln3 Δex7/8 knock-in mouse model of juvenile neuronal ceroid lipofuscinosis

Kabhilan Mohan; Yu Zhong; Jinpeng Liu; Ahmad Al-Attar; Huijuan Liu; Kyung Jung; Morgan Dow; Jinze Liu; Teresa Fan; Qing Jun Wang; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6030. doi:

ARVO Annual Meeting Abstract September 2016

HDAC1/2 are critical for RPE homeostasis and health

Mark Ellsworth Kleinman; Kyung Jung; Jacob Roney; Subhash C Prajapati; Dingyuan Lou; Sushil Dubey; Jennifer Brown; Kabhilan Mohan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3155. doi:

ARVO Annual Meeting Abstract September 2016

The role of IP-10 in RPE degeneration during AMD progression

Jacob Roney; Kabhilan Mohan; Kyung Jung; Dingyuan Lou; Subhash C Prajapati; Jennifer Brown; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6029. doi:

ARVO Annual Meeting Abstract June 2015

An Acyloxy-Conjugated Caspase Probe for In Vivo Retinal Bio-imaging

Kabhilan Mohan; Laura Sanman; Kyung Jung; Jacob Roney; Dingyuan Lou; Jennifer Brown; Matt Bogyo; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2338. doi:

ARVO Annual Meeting Abstract June 2015

Histone deacetylase expression and acetylation in the aging retinal pigment epithelium

Subhash C Prajapati; Andre Berner; Kabhilan Mohan; Kyung Jung; Jacob Roney; Dingyuan Lou; Jennifer Brown; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):801. doi:

ARVO Annual Meeting Abstract June 2015

Nucleoside reverse transcriptase inhibitor (NRTI) protection against iron cytotoxicity

Charles B Wright; Younghee Kim; Tetsuhiro Yasuma; Reo Yasuma; Shengjian Li; Benjamin J Fowler; Ana Bastos-Carvalho; Mark Ellsworth Kleinman; Jayakrishna Ambati; Bradley D Gelfand

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4211. doi:

ARVO Annual Meeting Abstract June 2015

Next Generation Sequencing of Mobile Genetic Elements in Dry Age-Related Macular Degeneration

Mark Ellsworth Kleinman; Joel T Lowery; Chen Liu; Benjamin J Fowler; Dingyuan Lou; Subhash C Prajapati; Bradley D Gelfand; Mehdi Keddache; Jinze Liu; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4212. doi:

ARVO Annual Meeting Abstract April 2014

Enhanced Alu RNA stability due to iron-mediated DICER1 impairment causes NLRP3 inflammasome priming

Charles B Wright; Younghee Kim; Tetsuhiro Yasuma; Shengjian Li; Benjamin J Fowler; Mark Ellsworth Kleinman; Jayakrishna Ambati; Bradley D Gelfand

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2187. doi:

ARVO Annual Meeting Abstract April 2014

Histone Deacetylase Expression and Inhibition in Age Related Macular Degeneration

Mark Ellsworth Kleinman; Andre Berner; Kablian Mohan; Ding-Yuan Lou; Jennifer Brown; Justin West; Rei Kono; Ilene Sugino; Marco Zarbin; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3457. doi:

ARVO Annual Meeting Abstract April 2014

RPE Cytotoxicity and Caspase Activation after Treatment with Valproic Acid

Andre Berner; Kablian Mohan; Ding-Yuan Lou; Jennifer Brown; Justin West; Rei Kono; Ilene K Sugino; Marco A Zarbin; Jayakrishna Ambati; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5991. doi:

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