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ARVO Annual Meeting Abstract June 2024

Histone expression profiling and epigenetic signatures in the aging human retinal pigment epithelium

Sushil Kumar Dubey; Rashmi Dubey; Kyung Sik Jung; Wenjian Tian; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1304.

ARVO Annual Meeting Abstract June 2024

Epigenetic Regulation of the MHC Class II Transactivator CIITA in Age-Related Macular Degeneration

Wenjian Tian; Sushil Kumar Dubey; Rashmi Dubey; Kyung Sik Jung; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1303.

ARVO Annual Meeting Abstract June 2023

HDAC1/2 inhibition induces cell-type dependent effects on viability and histone H3 and H4 acetylation

Kyung Sik Jung; Rashmi Dubey; Sushil Kumar Dubey; Nathaniel F Ashley; Wenjian (Vincent) Tian; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2108.

ARVO Annual Meeting Abstract June 2023

Transcriptomic analyses reveal inflammatory and immune-related gene expression changes in the aging mouse retinal pigment epithelium

Rashmi Dubey; Sushil Kumar Dubey; Kyung Sik Jung; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3016.

ARVO Annual Meeting Abstract June 2023

Age-related global histone loss and altered histone acetylation in retinal pigment epithelium

Sushil Kumar Dubey; Rashmi Dubey; Kyung Sik Jung; Subhash Prajapati; Wenjian Tian; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4444.

ARVO Annual Meeting Abstract June 2022

IL6 dysregulation in retinal pigment epithelium of global Cas9 expressing mouse strain

Sushil Kumar Dubey; Kabhilan Mohan; kyung sik jung; Rashmi Dubey; Qing Jun Wang; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):89 – A0062.

ARVO Annual Meeting Abstract June 2022

CCL26 expression is elevated in the retinal pigment epithelium in atrophic AMD

Rashmi Dubey; Sushil Kumar Dubey; kyung sik jung; Kabhilan Mohan; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):28.

ARVO Annual Meeting Abstract June 2022

Acetyl-histone profiling of degenerating RPE after selective HDAC1/2 inhibition

Mark Ellsworth Kleinman; Rashmi Dubey; kyung sik jung; Alex Davila; Sushil Kumar Dubey

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):799 – F0358.

ARVO Annual Meeting Abstract June 2022

Technique Optimization for Long-term Culture of Human Primary Retinal Pigment Epithelium Cells

kyung sik jung; Sushil Kumar Dubey; Rashmi Dubey; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3159 – F0433.

ARVO Annual Meeting Abstract June 2021

Histone deacetylases 1 and 2 regulate chromatin modifying enzymes in mouse retinal pigment epithelium

Sushil Kumar Dubey; Kabhilan Mohan; Kyung-Sik Jung; Jinze Liu; Qing Jun Wang; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3116.

ARVO Annual Meeting Abstract July 2018

withdrawn - Normal Retinal Phenotype in the Aged Global Cas9 Expressing Mouse Strain

Mark Ellsworth Kleinman; Kyung Sik Jung; Sushil Dubey

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):386.

ARVO Annual Meeting Abstract June 2017

Epigenetic regulation of autophagy by histone deacetylases in retinal pigment epithelium

Sushil Kumar Dubey; Dingyuan Lou; Jacob Roney; Kyung Jung; Jennifer Brown; Kabhilan Mohan; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5253.

ARVO Annual Meeting Abstract June 2017

Safety and efficiency of CRISPR-Cas9 gene editing in the retinal pigment epithelium

Mark Ellsworth Kleinman; Sushil Kumar Dubey; Kyung Jung; Jacob Roney; Dingyuan Lou; Jennifer Brown; Kabhilan Mohan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1981.

ARVO Annual Meeting Abstract June 2017

Neutralization of IFNAR1 prevents histone deacetylase inhibitor induced retinal pigment epithelium cell death

kyung sik jung; Kabhilan Mohan; Subhash Prajapati; Sushil Kumar Dubey; Dingyuan Lou; Jacob Roney; Jennifer Brown; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1987.

ARVO Annual Meeting Abstract September 2016

HDAC1/2 are critical for RPE homeostasis and health

Mark Ellsworth Kleinman; Kyung Jung; Jacob Roney; Subhash C Prajapati; Dingyuan Lou; Sushil Dubey; Jennifer Brown; Kabhilan Mohan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3155.

ARVO Annual Meeting Abstract September 2016

The role of IP-10 in RPE degeneration during AMD progression

Jacob Roney; Kabhilan Mohan; Kyung Jung; Dingyuan Lou; Subhash C Prajapati; Jennifer Brown; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6029.

ARVO Annual Meeting Abstract September 2016

Retinal pigment epithelium atrophy in the Cln3 Δex7/8 knock-in mouse model of juvenile neuronal ceroid lipofuscinosis

Kabhilan Mohan; Yu Zhong; Jinpeng Liu; Ahmad Al-Attar; Huijuan Liu; Kyung Jung; Morgan Dow; Jinze Liu; Teresa Fan; Qing Jun Wang; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6030.

ARVO Annual Meeting Abstract June 2015

Histone deacetylase expression and acetylation in the aging retinal pigment epithelium

Subhash C Prajapati; Andre Berner; Kabhilan Mohan; Kyung Jung; Jacob Roney; Dingyuan Lou; Jennifer Brown; Mark Ellsworth Kleinman

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):801.

ARVO Annual Meeting Abstract June 2015

Nucleoside reverse transcriptase inhibitor (NRTI) protection against iron cytotoxicity

Charles B Wright; Younghee Kim; Tetsuhiro Yasuma; Reo Yasuma; Shengjian Li; Benjamin J Fowler; Ana Bastos-Carvalho; Mark Ellsworth Kleinman; Jayakrishna Ambati; Bradley D Gelfand

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4211.

ARVO Annual Meeting Abstract June 2015

Next Generation Sequencing of Mobile Genetic Elements in Dry Age-Related Macular Degeneration

Mark Ellsworth Kleinman; Joel T Lowery; Chen Liu; Benjamin J Fowler; Dingyuan Lou; Subhash C Prajapati; Bradley D Gelfand; Mehdi Keddache; Jinze Liu; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4212.

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