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ARVO Annual Meeting Abstract June 2020

Towards retinal regeneration: Reprogramming retinal glial cells into photoreceptors using CRISPRa

Raymond Wong; Tu Nguyen; Lyujie Fang; Sam Lukowski; Camden Lo; Sandy Hung; Chi D Luu; Mark C Gillies; Alex W Hewitt

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2497. doi:

ARVO Annual Meeting Abstract June 2020

PD98059 inhibits the activation of mitogen-activated protein kinase in stressed Müller cells and protects photoreceptor from degeneration

Shaoxue Zeng; Ting Zhang; Michele C Madigan; Riccardo Carlo Natoli; Junjun Zhang; Nilisha Fernando; Joshua Aaron Chu-Tan; Ling Zhu; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3219. doi:

ARVO Annual Meeting Abstract June 2020

Comparison of glucose metabolism in human macula and peripheral retina

Ting Zhang; Shaoxue Zeng; Michele C Madigan; Meidong Zhu; Jianhai Du; Weiyong Shen; Ling Zhu; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3539. doi:

ARVO Annual Meeting Abstract June 2020

Association between anatomical and clinical outcomes in patients treated with anti-vascular endothelial growth factor for neovascular age-related macular degeneration

Mark C Gillies; Vuong Nguyen; Calvo Pilar; Martin Puzo; Pierre-Henry GABRIELLE; Catherine P Creuzot Garcher; Florian Baudin; Benjamin Wolff; Louise O’ Toole; Laurent Castelnovo; Michel Guillaume; Daniel Barthelmes

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4214. doi:

ARVO Annual Meeting Abstract June 2020

Ranibizumab or Aflibercept for Diabetic Macular Edema: One-Year Comparison of Real-World Outcomes from Fight Retinal Blindness! Registry.

SANJEEB BHANDARI; Vuong Nguyen; Samantha Fraser-Bell; Hemal Mehta; Francesco Viola; Florian Baudin; Pierre-Henry Gabrielle; Catherine P Creuzot Garcher; Mark C Gillies; Daniel Barthelmes

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3289. doi:

ARVO Annual Meeting Abstract June 2020

Disease Activity Assessments with Brolucizumab vs Aflibercept in Patients with nAMD in HAWK and HARRIER

Rishi P Singh; Robin Hamilton; Jeffrey S Heier; Carl Regillo; Mark C Gillies; Georges Weissgerber; Jahangir Alam; Pravin U Dugel

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1158. doi:

Genetics September 2019

MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus

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Ebony Liu; Georgia Kaidonis; Bennet J. McComish; Mark C. Gillies; Sotoodeh Abhary; Rohan W. Essex; John H. Chang; Bishwanath Pal; Mark Daniell; Stewart Lake; Nikolai Petrovsky; Alex W. Hewitt; Alicia Jenkins; Ecosse L. Lamoureux; Jonathan M. Gleadle; Jamie E. Craig; Kathryn P. Burdon
TAGS: diabetes mellitus, type 1, diabetic retinopathy, genes, genetics, micrornas, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3937-3942. doi: https://doi.org/10.1167/iovs.18-25570

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Ten-Year Treatment Outcomes of Neovascular Age-Related Macular Degeneration

Mark C Gillies; SANJEEB BHANDARI; Benjamin Wolff; Jennifer Joan Arnold; Rohan W Essex; Stephanie Young; David M Squirrell; Daniel Barthelmes; Vuong Nguyen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):111. doi:

ARVO Annual Meeting Abstract July 2019

Outcomes of suspending VEGF inhibitors for neovascular age-related macular degeneration when lesions have been inactive for 3 months

Vuong Nguyen; Anagha Vaze; Samanta Fraser-Bell; Jennifer Joan Arnold; Rohan W Essex; Daniel Barthelmes; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):139. doi:

ARVO Annual Meeting Abstract July 2019

Changes in real world treatment patterns for diabetic macular edema and five year treatment outcomes: data from the Fight Retinal Blindness! Project

SANJEEB BHANDARI; Anne Catherine Biechl; Jennifer Joan Arnold; Stephanie Young; Samanta Fraser-Bell; Hemal Mehta; Mark C Gillies; Daniel Barthelmes; Vuong Nguyen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2602. doi:

ARVO Annual Meeting Abstract July 2019

Twenty-four month outcomes of inflammatory choroidal neovascularization treated with intravitreal anti vascular endothelial growth factors: a comparison between two treatment regimens

Alessandro Invernizzi; Francesco Pichi; Richard Symes; Sophia Zagora; Vuong Nguyen; Stefano Erba; Alba Xhepa; Luca De Simone; Luca Cimino; Mark C Gillies; Peter J McCluskey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3859. doi:

ARVO Annual Meeting Abstract July 2019

Real-world outcomes in patients with macular oedema secondary to central retinal vein occlusion receiving intravitreal anti-VEGF therapy in a UK public hospital setting

Sarah Ah-Moye; Pardis Zalmay; Magnus Theodorsson; Martin Lynn Harris; Riaz Asaria; Adrian Hunt; Daniel Barthelmes; Mark C Gillies; Vuong Nguyen; Hemal Mehta

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4061. doi:

ARVO Annual Meeting Abstract July 2019

Selectively knocking down insulin receptor in rods disrupts glucose flux and leads to photoreceptor degeneration

Rui Zhang; Weiyong Shen; Victoria Pye; Ashish Easow Mathai; So-Ra Lee; Michelle Yam; Ling Zhu; Ching-Kang Jason Chen; Jianhai Du; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1670. doi:

ARVO Annual Meeting Abstract July 2019

Comparison of Serine Biosynthesis in Human Retinal Pigment Epithelium from the Macula and Periphery

Ting Zhang; Shaoxue Zeng; Ling Zhu; Weiyong Shen; Jiawen Fan; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1701. doi:

ARVO Annual Meeting Abstract July 2019

A bioenergetic crisis in the retinal pigment epithelium contributes to photoreceptor degeneration

Weiyong Shen; Ashish Easow Mathai; Victoria Pye; So-Ra Lee; Michelle X. Yam; Rui Zhang; Ling Zhu; Pankaj Seth; Joshua L Dunaief; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3866. doi:

ARVO Annual Meeting Abstract July 2019

The differential expression of aquaporin-4 (AQP4) in Müller cells from human macular and peripheral retina.

Ling Zhu; Yuyi You; Ting Zhang; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4392. doi:

ARVO Annual Meeting Abstract July 2019

A randomised clinical trial of slow versus fast intravitreal injection of ranibizumab (Lucentis®) and its impact on intraocular pressure (the Speed IOP Study)

Samantha Fraser-Bell; Sophia Zagora; Hemal Mehta; Anna Campain; Hon Seng Wong; Yeung Aaron; Mark C Gillies

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):79. doi:

Retinal Cell Biology December 2018

A Combination Therapy Targeting Endoglin and VEGF-A Prevents Subretinal Fibro-Neovascularization Caused by Induced Müller Cell Disruption

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Weiyong Shen; So-Ra Lee; Michelle Yam; Ling Zhu; Ting Zhang; Victoria Pye; Ashish Easow Mathai; Keiichi Shibagaki; Jin-Zhong Zhang; Takeshi Matsugi; Mark C. Gillies
TAGS: endoglin, neovascularization, pathologic, vascular endothelial growth factor a, antibodies, combined modality therapy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6075-6088. doi: https://doi.org/10.1167/iovs.18-25628

Includes: Supplemental Content

Retina August 2018

Choroidal Structural Changes Correlate With Neovascular Activity in Neovascular Age Related Macular Degeneration

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Alessandro Invernizzi; Eleonora Benatti; Mariano Cozzi; Stefano Erba; Shiva Vaishnavi; Kiran Kumar Vupparaboina; Giovanni Staurenghi; Jay Chhablani; Mark Gillies; Francesco Viola
TAGS: age-related macular degeneration, choroid, choroidal neovascularization, cortical blindness, eye, follow-up
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3836-3841. doi: https://doi.org/10.1167/iovs.18-23960

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract July 2018

Comparison of Ranibizumab and Aflibercept in Patients with Neovascular Age-Related Macular Degeneration treated following a ‘Treat and Extend’ protocol: efficacy variables from the pre-specified 12-month interim analysis of the RIVAL study

Mark C Gillies; Alex Hunyor; Jennifer Arnold; Francois Pecheur; Kathryn Underhill; Robyn H Guymer; Ian McAllister

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):840. doi:

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Towards retinal regeneration: Reprogramming retinal glial cells into photoreceptors using CRISPRa

PD98059 inhibits the activation of mitogen-activated protein kinase in stressed Müller cells and protects photoreceptor from degeneration

Comparison of glucose metabolism in human macula and peripheral retina

Association between anatomical and clinical outcomes in patients treated with anti-vascular endothelial growth factor for neovascular age-related macular degeneration

Ranibizumab or Aflibercept for Diabetic Macular Edema: One-Year Comparison of Real-World Outcomes from Fight Retinal Blindness! Registry.

Disease Activity Assessments with Brolucizumab vs Aflibercept in Patients with nAMD in HAWK and HARRIER

MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus

Ten-Year Treatment Outcomes of Neovascular Age-Related Macular Degeneration

Outcomes of suspending VEGF inhibitors for neovascular age-related macular degeneration when lesions have been inactive for 3 months

Changes in real world treatment patterns for diabetic macular edema and five year treatment outcomes: data from the Fight Retinal Blindness! Project

Twenty-four month outcomes of inflammatory choroidal neovascularization treated with intravitreal anti vascular endothelial growth factors: a comparison between two treatment regimens

Real-world outcomes in patients with macular oedema secondary to central retinal vein occlusion receiving intravitreal anti-VEGF therapy in a UK public hospital setting

Selectively knocking down insulin receptor in rods disrupts glucose flux and leads to photoreceptor degeneration

Comparison of Serine Biosynthesis in Human Retinal Pigment Epithelium from the Macula and Periphery

A bioenergetic crisis in the retinal pigment epithelium contributes to photoreceptor degeneration

The differential expression of aquaporin-4 (AQP4) in Müller cells from human macular and peripheral retina.

A randomised clinical trial of slow versus fast intravitreal injection of ranibizumab (Lucentis®) and its impact on intraocular pressure (the Speed IOP Study)

A Combination Therapy Targeting Endoglin and VEGF-A Prevents Subretinal Fibro-Neovascularization Caused by Induced Müller Cell Disruption

Choroidal Structural Changes Correlate With Neovascular Activity in Neovascular Age Related Macular Degeneration

Comparison of Ranibizumab and Aflibercept in Patients with Neovascular Age-Related Macular Degeneration treated following a ‘Treat and Extend’ protocol: efficacy variables from the pre-specified 12-month interim analysis of the RIVAL study

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