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ARVO Annual Meeting Abstract June 2025

T-cell mediated retinal ganglion cell loss is facilitated by mild elevation in intraocular pressure

Jordan Mayberry; Shuyu Xian; Markus H Kuehn

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4897.

ARVO Annual Meeting Abstract June 2025

Magnetic Guidance of Adipose-Derived Mesenchymal Stem Cells in Human Ocular Perfusion Culture

Markus H Kuehn; Yuyza Irizarry; Catherine A A Lee; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3025.

Perspective December 2024

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

PDF

Ted S. Acott; Michael P. Fautsch; Weiming Mao; C. Ross Ethier; Alex S. Huang; Mary J. Kelley; Mini Aga; Sanjoy K. Bhattacharya; Terete Borras; Diane Bovenkamp; Uttio Roy Chowdhury; Abbot F. Clark; Mohammed I. Dibas; Yiqin Du; Michael H. Elliott; Jennifer A. Faralli; Haiyan Gong; Samuel Herberg; Murray A. Johnstone; Paul L. Kaufman; Kate E. Keller; Ruth A. Kelly; David Krizaj; Markus H. Kuehn; Hoi Lam Li; Raquel Lieberman; Shan C. Lin; Yutao Liu; Fiona S. McDonnell; Colleen M. McDowell; Gillian J. McLellan; Philip Mzyk; Kayarat Saidas Nair; Darryl R. Overby; Donna M. Peters; VijayKrishna Raghunathan; Ponugoti Vasantha Rao; Gavin W. Roddy; Najam A. Sharif; Myoung Sup Shim; Yang Sun; Benjamin R. Thomson; Carol B. Toris; Colin E. Willoughby; Hao F. Zhang; Thomas F. Freddo; Rudolf Fuchshofer; Kamisha R. Hill; Alireza Karimi; Krishnakumar Kizhatil; Casey C. Kopcyznski; Paloma Liton; Gaurang Patel; Michael Peng; Padmanabhan P. Pattabiraman; Ganesh Prasanna; Ester Reina-Torres; E. Griffen Samples; John R. Samples; Cynthia L. Steel; Clemens A. Strohmaier; Preeti Subramanian; Chenna Kesavulu Sugali; Joseph van Batenburg-Sherwood; Cydney Wong; Hannah Youngblood; Gulab S. Zode; Elizabeth White; W. Daniel Stamer
TAGS: body tissue, eye, fluid flow, intraocular pressure, perfusion, regulation, organ culture techniques
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):32. https://doi.org/10.1167/iovs.65.14.32

ARVO Annual Meeting Abstract June 2024

Magnetically-steered Human Mesenchymal Stem Cells Lower Intraocular Pressure (IOP) for 9 Months in Mice

C Ross Ethier; M. Reza Bahrani Fard; Jessica T. Chan; A. Thomas Read; Guorong Li; Lin Cheng; Anamik Jhunjhunwala; Babak N. Safa; Seyed Mohammad Siadat; Hans E Grossniklaus; Stanislav Y. Emelianov; W Daniel Stamer; Markus H Kuehn

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6460.

ARVO Annual Meeting Abstract June 2024

Contribution of CD4 and CD8 cells to retinal ganglion cell loss in glaucoma

Jordan Mayberry; Huilan Zeng; Markus H Kuehn

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):572.

ARVO Annual Meeting Abstract June 2024

Reduced abundance of trabecular meshwork stem cells in human donor eyes with POAG

Sarah Brumley; Markus H Kuehn

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5170.

ARVO Annual Meeting Abstract June 2023

Quantifying specificity of stem cell delivery to the trabecular meshwork

M. Reza Bahrani Fard; Jessica Chan; Marybeth Yonk; A. Thomas Read; Shreya R Kuturu; Stanislav Y Emelianov; Markus H Kuehn; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1558.

ARVO Annual Meeting Abstract June 2023

Loss of SARM1 imparts retinal ganglion cell protection in a glaucoma model of chronic IOP elevation

Markus H Kuehn; David Wadkins; Huilan zeng

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1902.

ARVO Annual Meeting Abstract June 2023

Increased T-regulatory cell activity protects retinal ganglion cells in glaucoma

Huilan zeng; Markus H Kuehn

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3922.

ARVO Annual Meeting Abstract June 2022

Immune cell- mediated experimental RGC loss is correlated with glaucoma donors’ ophthalmic metrics

Huilan zeng; Oliver W Gramlich; David Wadkins; Markus H Kuehn

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):944 – A0413.

ARVO Annual Meeting Abstract June 2022

T-cell profiling of glaucoma patients

Markus H Kuehn; Huilan Zeng; Wallace Alward; Young H Kwon; John H Fingert; Nathan Sears; Randy H Kardon; Oliver W Gramlich

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):942 – A0411.

ARVO Annual Meeting Abstract June 2022

Ethambutol-induced optic atrophy: a mitochondrial fission neuropathy mediated by NO?

Lin Cheng; Hanna Shevalye; Gregory Schmidt; Jessica Skeie; Mark A Greiner; Markus H Kuehn

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1490.

Perspective February 2022

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

PDF

Colleen M. McDowell; Krishnakumar Kizhatil; Michael H. Elliott; Darryl R. Overby; Joseph van Batenburg-Sherwood; J. Cameron Millar; Markus H. Kuehn; Gulab Zode; Ted S. Acott; Michael G. Anderson; Sanjoy K. Bhattacharya; Jacques A. Bertrand; Terete Borras; Diane E. Bovenkamp; Lin Cheng; John Danias; Michael Lucio De Ieso; Yiqin Du; Jennifer A. Faralli; Rudolf Fuchshofer; Preethi S. Ganapathy; Haiyan Gong; Samuel Herberg; Humberto Hernandez; Peter Humphries; Simon W. M. John; Paul L. Kaufman; Kate E. Keller; Mary J. Kelley; Ruth A. Kelly; David Krizaj; Ajay Kumar; Brian C. Leonard; Raquel L. Lieberman; Paloma Liton; Yutao Liu; Katy C. Liu; Navita N. Lopez; Weiming Mao; Timur Mavlyutov; Fiona McDonnell; Gillian J. McLellan; Philip Mzyk; Andrews Nartey; Louis R. Pasquale; Gaurang C. Patel; Padmanabhan P. Pattabiraman; Donna M. Peters; Vijaykrishna Raghunathan; Ponugoti Vasantha Rao; Naga Rayana; Urmimala Raychaudhuri; Ester Reina-Torres; Ruiyi Ren; Douglas Rhee; Uttio Roy Chowdhury; John R. Samples; E. Griffen Samples; Najam Sharif; Joel S. Schuman; Val C. Sheffield; Cooper H. Stevenson; Avinash Soundararajan; Preeti Subramanian; Chenna Kesavulu Sugali; Yang Sun; Carol B. Toris; Karen Y. Torrejon; Amir Vahabikashi; Janice A. Vranka; Ting Wang; Colin E. Willoughby; Chen Xin; Hongmin Yun; Hao F. Zhang; Michael P. Fautsch; Ernst R. Tamm; Abbot F. Clark; C. Ross Ethier; W. Daniel Stamer
TAGS: eye, mice, ocular hypertension, intraocular pressure, perfusion
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):12. https://doi.org/10.1167/iovs.63.2.12

Glaucoma August 2021

iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma

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Shangru Sui; Hongxia Yu; Xiangji Wang; Wenyan Wang; Xuejiao Yang; Xiaojing Pan; Qingjun Zhou; Chen Xin; Rong Du; Shen Wu; Jingxue Zhang; Qilong Cao; Ningli Wang; Markus H. Kuehn; Wei Zhu
TAGS: cell growth, connexin 43, gap junction protein, glaucoma, medication therapy management, mice, trabecular meshwork, myoc gene, coculture techniques, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):28. https://doi.org/10.1167/iovs.62.10.28

Includes: Supplemental Content

Articles May 2021

Xeno- and Feeder-Free Differentiation of Human iPSCs to Trabecular Meshwork-Like Cells by Recombinant Cytokines

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Wenyan Wang; Yongzhen Miao; Shangru Sui; Yanan Wang; Shen Wu; Qilong Cao; Haoyun Duan; Xia Qi; Qingjun Zhou; Xiaojing Pan; Jingxue Zhang; Xuehong Chen; Yantao Han; Ningli Wang; Markus H. Kuehn; Wei Zhu
TAGS: cytokine, culture media, conditioned, reverse transcriptase polymerase chain reaction
Trans. Vis. Sci. Tech.. 2021; 10(6):27. https://doi.org/10.1167/tvst.10.6.27

Includes: Supplemental Content

Glaucoma December 2020

T and B Lymphocyte Deficiency in Rag1−/− Mice Reduces Retinal Ganglion Cell Loss in Experimental Glaucoma

PDF

Oliver W. Gramlich; Cheyanne R. Godwin; Neal D. Heuss; Dale S. Gregerson; Markus H. Kuehn

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):18. https://doi.org/10.1167/iovs.61.14.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Modeling oculodentodigital dysplasia syndrome using human induced pluripotent stem cells

Lin Cheng; Matthew R. Cring; Markus H Kuehn

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2878.

ARVO Annual Meeting Abstract July 2019

T and B Lymphocyte Deficiency in RAG1 Mice Decreases Retinal Ganglion Cell Loss in Experimental Glaucoma

Markus H Kuehn; Oliver W Gramlich; Neal D Heuss; Cheyanne R Godwin; Dale S Gregerson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2849.

Retina June 2019

Blast-Mediated Traumatic Brain Injury Exacerbates Retinal Damage and Amyloidosis in the APPswePSENd19e Mouse Model of Alzheimer's Disease

PDF

Matthew M. Harper; Adam Hedberg-Buenz; Judith Herlein; Eric E. Abrahamson; Michael G. Anderson; Markus H. Kuehn; Randy H. Kardon; Pieter Poolman; Milos D. Ikonomovic
TAGS: alzheimer's disease, amyloidosis, basic local alignment search tool, mice, nerve degeneration, traumatic brain injuries, optic nerve, brain, retina, blast injuries
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2716-2725. https://doi.org/10.1167/iovs.18-26353

ARVO Annual Meeting Abstract July 2018

Transfer of peripheral blood mononuclear cells from human glaucoma patients to NOD/scid gamma mice elicits loss of retinal ganglion cells in recipients

Markus H Kuehn; Oliver W Gramlich; John H Fingert; Young H Kwon; Wallace L M Alward

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3731.

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T-cell mediated retinal ganglion cell loss is facilitated by mild elevation in intraocular pressure

Magnetic Guidance of Adipose-Derived Mesenchymal Stem Cells in Human Ocular Perfusion Culture

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

Magnetically-steered Human Mesenchymal Stem Cells Lower Intraocular Pressure (IOP) for 9 Months in Mice

Contribution of CD4 and CD8 cells to retinal ganglion cell loss in glaucoma

Reduced abundance of trabecular meshwork stem cells in human donor eyes with POAG

Quantifying specificity of stem cell delivery to the trabecular meshwork

Loss of SARM1 imparts retinal ganglion cell protection in a glaucoma model of chronic IOP elevation

Increased T-regulatory cell activity protects retinal ganglion cells in glaucoma

Immune cell- mediated experimental RGC loss is correlated with glaucoma donors’ ophthalmic metrics

T-cell profiling of glaucoma patients

Ethambutol-induced optic atrophy: a mitochondrial fission neuropathy mediated by NO?

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma

Xeno- and Feeder-Free Differentiation of Human iPSCs to Trabecular Meshwork-Like Cells by Recombinant Cytokines

T and B Lymphocyte Deficiency in Rag1−/− Mice Reduces Retinal Ganglion Cell Loss in Experimental Glaucoma

Modeling oculodentodigital dysplasia syndrome using human induced pluripotent stem cells

T and B Lymphocyte Deficiency in RAG1 Mice Decreases Retinal Ganglion Cell Loss in Experimental Glaucoma

Blast-Mediated Traumatic Brain Injury Exacerbates Retinal Damage and Amyloidosis in the APPswePSENd19e Mouse Model of Alzheimer's Disease

Transfer of peripheral blood mononuclear cells from human glaucoma patients to NOD/scid gamma mice elicits loss of retinal ganglion cells in recipients

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